Subasree Ramakrishnan
YOU?
Author Swipe
View article: Focal cerebral arteriopathy in adults: A single centre experience
Focal cerebral arteriopathy in adults: A single centre experience Open
Background and Objectives Focal cerebral arteriopathy (FCA) is a recognized cause of pediatric stroke, but its presentation in adults is poorly defined, with limited cohorts and scarce advanced imaging data. We aimed to describe the clinic…
View article: Multimodal Imaging and Logistic Weighted Cognitive Scores for Classification of MCI, AD, and FTD Subtypes
Multimodal Imaging and Logistic Weighted Cognitive Scores for Classification of MCI, AD, and FTD Subtypes Open
Background Differentiating between mild cognitive impairment (MCI), Alzheimer’s disease (AD), and frontotemporal dementia (FTD) subtypes remains a clinical challenge due to overlapping cognitive symptoms, structural atrophy, and metabolic …
View article: Clinical profile, atrophy and inheritance patterns of pathogenic MAPT gene mutations in Frontotemporal dementia detected using whole exome sequencing: a single-center first report from India
Clinical profile, atrophy and inheritance patterns of pathogenic MAPT gene mutations in Frontotemporal dementia detected using whole exome sequencing: a single-center first report from India Open
In the Indian context, pathogenic MAPT in FTD is being reported for the first time and notably from a single center by WES. Identifying pathogenic MAPT genes is important in planning mutation-specific clinical trials and understanding ethi…
View article: Intersection of Autoimmunity: NMDA Positivity, Hypertrophic Pachymeningitis, and Primary CNS Angiitis in a Single Patient – A Diagnostic Challenge
Intersection of Autoimmunity: NMDA Positivity, Hypertrophic Pachymeningitis, and Primary CNS Angiitis in a Single Patient – A Diagnostic Challenge Open
View article: Thalamus as a neural marker of cognitive reserve in bilinguals with frontotemporal dementia
Thalamus as a neural marker of cognitive reserve in bilinguals with frontotemporal dementia Open
Bilingualism delays the onset of dementia symptoms and contributes to cognitive reserve. However, the neural basis of this mechanism remains elusive. The few studies that have investigated neural mechanisms of cognitive reserve and bilingu…
View article: Diagnostic value of fluid‐based non‐amyloid biomarkers for Alzheimer's disease and related dementias in a clinic‐based cohort from South Asia
Diagnostic value of fluid‐based non‐amyloid biomarkers for Alzheimer's disease and related dementias in a clinic‐based cohort from South Asia Open
INTRODUCTION The rising dementia burden and limited knowledge of fluid biomarkers in South Asians highlights this study's aim on evaluating their utility for the diagnosis of Alzheimer's disease and related dementias (ADRD). METHODS Partic…
View article: Gain of Function Presenting as Creative Skills in Patients with Progressive Cognitive Dysfunction and their fMRI Correlates: A Descriptive Study
Gain of Function Presenting as Creative Skills in Patients with Progressive Cognitive Dysfunction and their fMRI Correlates: A Descriptive Study Open
Background and Objectives: Patients with neurodegenerative disorders generally lose their acquired cognitive skills. However, a few of our patients showed creative skills in new areas, and we tried to evaluate a possible neural substrate f…
View article: Multiplex connectomics reveal altered networks in frontotemporal dementia: A multisite study
Multiplex connectomics reveal altered networks in frontotemporal dementia: A multisite study Open
A network neuroscience perspective can significantly advance the understanding of neurodegenerative disorders, particularly frontotemporal dementia (FTD). This study employed an innovative multiplex connectomics approach, integrating corti…
View article: Evaluating the potential of teleneurology in a low‐resource setting for dementia: An exploratory study on patient and healthcare provider satisfaction
Evaluating the potential of teleneurology in a low‐resource setting for dementia: An exploratory study on patient and healthcare provider satisfaction Open
Background and Objectives Telemedicine, including teleneurology, has emerged as a valuable tool for providing healthcare services remotely, particularly in situations where distance plays a critical role. Teleneurology has the potential to…
View article: Evaluating the potential of teleneurology in a low‐resource setting for dementia: An exploratory study on patient and healthcare provider satisfaction
Evaluating the potential of teleneurology in a low‐resource setting for dementia: An exploratory study on patient and healthcare provider satisfaction Open
Background and Objectives Telemedicine, including teleneurology, has emerged as a valuable tool for providing healthcare services remotely, particularly in situations where distance plays a critical role. Teleneurology has the potential to…
View article: Emerging role of serum biomarkers in neurodegenerative dementias in a diverse context
Emerging role of serum biomarkers in neurodegenerative dementias in a diverse context Open
Background The aetiology of Alzheimer’s Disease and Related dementias (ADRD) in a diverse context is complex, and clinical methods lack sensitivity and specificity due to overlapping symptoms. This underscores the need of novel serum bioma…
View article: Anticoagulation Status and Outcome in Cerebral Venous Thrombosis: A Single-Center Retrospective Study from South India
Anticoagulation Status and Outcome in Cerebral Venous Thrombosis: A Single-Center Retrospective Study from South India Open
Background and Objectives: Early initiation and maintenance of anticoagulation appears to be the mainstay of treatment of cerebral venous thrombosis (CVT), but the evidence supporting the intensity and duration of anticoagulation is limite…
View article: Robotic exoskeleton-assisted gait training in patients with motor incomplete myelopathy
Robotic exoskeleton-assisted gait training in patients with motor incomplete myelopathy Open
Objectives: To assess the effect of gait training with robotic exoskeleton-assisted rehabilitation systems on gait parameters, balance, and overall disability in motor incomplete myelopathy. Design: Prospective pre-post study. Setting: Neu…
View article: Characterization of Event Related Desynchronization in Chronic Stroke Using Motor Imagery Based Brain Computer Interface for Upper Limb Rehabilitation
Characterization of Event Related Desynchronization in Chronic Stroke Using Motor Imagery Based Brain Computer Interface for Upper Limb Rehabilitation Open
Objective: Motor imagery-based brain–computer interface (MI-BCI) is a promising novel mode of stroke rehabilitation. The current study aims to investigate the feasibility of MI-BCI in upper limb rehabilitation of chronic stroke survivors a…
View article: Carotid plaque volume measurement in ischemic stroke: A pilot study
Carotid plaque volume measurement in ischemic stroke: A pilot study Open
Objectives: Carotid atherosclerosis is a significant risk factor for acute ischemic stroke. Three-dimensional (3D) sonography is a new technique that can be used to analyze carotid plaque both quantitatively and qualitatively. The aim was …
View article: Characterization of Ocular Sonography Findings and their Relationship to Clinical Features from a South Indian Cohort of Idiopathic Intracranial Hypertension
Characterization of Ocular Sonography Findings and their Relationship to Clinical Features from a South Indian Cohort of Idiopathic Intracranial Hypertension Open
Background: Idiopathic intracranial hypertension (IIH) typically manifests with headache, accompanied by papilledema and visual loss, and has a higher prevalence in females. In recent years, ocular sonography, particularly, measurement of …
View article: Primary microgliopathy presenting as degenerative dementias: A case series of novel gene mutations from India
Primary microgliopathy presenting as degenerative dementias: A case series of novel gene mutations from India Open
Introduction Microglia exert a crucial role in homeostasis of white matter integrity and several studies highlight the role of microglial dysfunctions in neurodegeneration. Primary microgliopathy are disorders where the pathogenic abnormal…
View article: Variational mode decomposition-based EEG analysis for the classification of disorders of consciousness
Variational mode decomposition-based EEG analysis for the classification of disorders of consciousness Open
Aberrant alterations in any of the two dimensions of consciousness, namely awareness and arousal, can lead to the emergence of disorders of consciousness (DOC). The development of DOC may arise from more severe or targeted lesions in the b…
View article: Platelet ADP receptor (P2RY1) polymorphism and the risk of inadequate platelet response to aspirin: Study in patients with ischemic stroke
Platelet ADP receptor (P2RY1) polymorphism and the risk of inadequate platelet response to aspirin: Study in patients with ischemic stroke Open
An estimated 5–60% of patients experience inadequate antiplatelet effects after taking aspirin. We investigated the gene variants that might determine the outcome of the aspirin response in stroke patients. A total of 293 ischemic stroke p…
View article: Novel Pathogenic Missense <i>NF1</i>-Variant Associated With Cognitive Impairment
Novel Pathogenic Missense <i>NF1</i>-Variant Associated With Cognitive Impairment Open
View article: Clinicoradiological Features and Long-term Cognitive and Functional Outcome in Patients with Deep Cerebral Venous Thrombosis
Clinicoradiological Features and Long-term Cognitive and Functional Outcome in Patients with Deep Cerebral Venous Thrombosis Open
Background: Deep cerebral venous thrombosis (DCVT) can have long-term functional and cognitive sequelae. Although literature exists on cognitive impairment after arterial stroke, cognitive sequelae after cerebral venous thrombosis (CVT) ar…
View article: Alzheimer’s disease is associated with increased modularity and assortativity: Evidence from structural and metabolic connectivity
Alzheimer’s disease is associated with increased modularity and assortativity: Evidence from structural and metabolic connectivity Open
Background Alzheimer’s disease (AD) is a progressive disorder associated with cognitive dysfunction that alters brain connectivity and assessing these altered connectivity patterns has become a topic of increasing interest. In this study, …
View article: Familial FTD in India
Familial FTD in India Open
Background The burden of dementia in India is estimated to increase by 197% by 2050, and Frontotemporal dementia (FTD) is among the leading causes of young‐onset dementia. With recent advances in molecular pathology, genetic mechanisms and…
View article: Speech and Language characteristics of Kannada and Hindi speaking individuals with Primary Progressive Aphasia
Speech and Language characteristics of Kannada and Hindi speaking individuals with Primary Progressive Aphasia Open
Background Linguistic typology plays an important role in identifying clinical markers of language deficits that characterise Primary Progressive Aphasia (PPA). The current International criteria to diagnose PPA were primarily developed fo…
View article: Genotype Phenotype characterisation, Imaging profile and novel genetic mutations from a large cohort of Frontotemporal Dementia from India
Genotype Phenotype characterisation, Imaging profile and novel genetic mutations from a large cohort of Frontotemporal Dementia from India Open
Background Degenerative dementia like Frontotemporal dementia (FTD) are complex heterogeneous disorders with variable phenotypes, patterns of atrophy and pathogenicity. Advanced genetic studies from India are sparse and earlier techniques …
View article: Vascular risk factors are a major contributor to cognitive impairment and degenerative dementia in India
Vascular risk factors are a major contributor to cognitive impairment and degenerative dementia in India Open
Background The burden of vascular contribution to cognitive impairment and dementia is high in low and middle‐income countries (LMIC) like India. It is crucial to determine burden of vascular contribution to dementia in India, to develop e…
View article: Surgical Management of Vision Loss in Cerebral Venous Thrombosis: Case Series from a Tertiary Care Stroke Center
Surgical Management of Vision Loss in Cerebral Venous Thrombosis: Case Series from a Tertiary Care Stroke Center Open
Background and Purpose: Cerebral venous thrombosis (CVT) presenting as vision loss is uncommon. Raised intracranial tension in CVT is proposed as one of the mechanisms (13.2%). There are still unknown underlying mechanisms to explain visio…
View article: Cerebral Venous Sinus Thrombosis Associated Subdural Hematoma: A Case Series on Clinical Presentation and Management
Cerebral Venous Sinus Thrombosis Associated Subdural Hematoma: A Case Series on Clinical Presentation and Management Open
Diagnosis and treatment of cerebral venous sinus thrombosis (CVT) associated with subdural hematoma (SDH) is challenging with an increased risk of rebleeding on using anticoagulation. There are no guidelines at present due to its rare pres…
View article: Effect of overground gait training with ‘Mobility Assisted Robotic System-MARS’ on gait parameters in patients with stroke: a pre-post study
Effect of overground gait training with ‘Mobility Assisted Robotic System-MARS’ on gait parameters in patients with stroke: a pre-post study Open
View article: Effect of Overground Gait Training with ‘Mobility Assisted Robotic System-MARS’ on Gait Parameters in Patients with Stroke: A Pre-post Study
Effect of Overground Gait Training with ‘Mobility Assisted Robotic System-MARS’ on Gait Parameters in Patients with Stroke: A Pre-post Study Open
Objective To observe the effect of overground gait training with ‘Mobility Assisted Robotic System-MARS’ on gait parameters in patients with stroke Patients & Methods: This prospective pre-post study was conducted in a tertiary teaching re…