Subhash Rajpurohit
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View article: <i>Drosophila melanogaster</i> pigmentation demonstrates adaptive phenotypic parallelism over multiple spatiotemporal scales
<i>Drosophila melanogaster</i> pigmentation demonstrates adaptive phenotypic parallelism over multiple spatiotemporal scales Open
Populations are capable of responding to environmental change over ecological timescales via adaptive tracking. However, the translation from patterns of allele frequency change to rapid adaptation of complex traits remains unresolved. We …
View article: Wing spot in a tropical and a temperate drosophilid: C = C enrichment and conserved thermal response
Wing spot in a tropical and a temperate drosophilid: C = C enrichment and conserved thermal response Open
Wings are primarily used in flight but also play a role in mating behaviour in many insects. Drosophila species exhibit a variety of pigmentation patterns on their wings. In some sexually dimorphic Drosophilids, a pigmented spot pattern is…
View article: Pervasive fitness trade-offs revealed by rapid adaptation to shifting population densities in large experimental populations of <i>Drosophila melanogaster</i>
Pervasive fitness trade-offs revealed by rapid adaptation to shifting population densities in large experimental populations of <i>Drosophila melanogaster</i> Open
Trade-offs are an inherent feature of organismal biology that are expected play a fundamental role in the evolution of natural populations. Efforts to quantify trade-offs are largely confined to phenotypic measurements and the identificati…
View article: Structural colouration in Drosophila wings is thermally plastic and exhibits ecological variation
Structural colouration in Drosophila wings is thermally plastic and exhibits ecological variation Open
Introduction Structural colour patterns and their functions in insect wings are less known. Wing interference patterns (WIPs) are colour patterns apparent when wings are viewed against black backgrounds; the angle of incident light and win…
View article: <i>Drosophila melanogaster</i>pigmentation demonstrates adaptive phenotypic parallelism but genomic unpredictability over multiple timescales
<i>Drosophila melanogaster</i>pigmentation demonstrates adaptive phenotypic parallelism but genomic unpredictability over multiple timescales Open
Populations are capable of responding to environmental change over ecological timescales via adaptive tracking. However, the translation from patterns of allele frequency change to rapid adaptation of complex traits remains unresolved. We …
View article: Dynamic Bayesian modeling of the social behavior of<i>Drosophila melanogaster</i>
Dynamic Bayesian modeling of the social behavior of<i>Drosophila melanogaster</i> Open
Organismal behavior has always been a challenge to understand. Insects are one of the amenable systems used to understand behavior. A striking variety of insect behaviors gain support from genetic and physiological studies. Drosophila , a …
View article: Tropical High-Altitude Insects Show Limited Capacity to Handle High Temperatures
Tropical High-Altitude Insects Show Limited Capacity to Handle High Temperatures Open
View article: Tropical High-Altitude Insects Show Limited Capacity to Handle High Temperatures
Tropical High-Altitude Insects Show Limited Capacity to Handle High Temperatures Open
View article: An Interactive Protocol for In-Classroom DNA Extraction
An Interactive Protocol for In-Classroom DNA Extraction Open
Using commonly available materials, this tool allows students to extract DNA, exploring DNA chemistry and the principles of experimental design and execution. We take a “Choose Your Own Adventure” approach encouraging students to explore t…
View article: Clinal variation as a tool to understand climate change
Clinal variation as a tool to understand climate change Open
Clines are observable gradients that reflect continuous change in biological traits of species across geographical ranges. Clinal gradients could vary at geographic scales (latitude and altitude). Since clinal variations represent active g…
View article: Tropical high-altitude insects show limited capacity to handle high temperatures
Tropical high-altitude insects show limited capacity to handle high temperatures Open
Growing summer season and increased anthropogenic activities pose a continual challenge to resident species. Ectotherms like insects are especially vulnerable to rapid climatic changes. High-altitude tropical insect populations have been r…
View article: Correction to: Cuticle darkening correlates with increased body copper content in Drosophila melanogaster
Correction to: Cuticle darkening correlates with increased body copper content in Drosophila melanogaster Open
View article: Direct observation of adaptive tracking on ecological time scales in <i>Drosophila</i>
Direct observation of adaptive tracking on ecological time scales in <i>Drosophila</i> Open
Direct observation of evolution in response to natural environmental change can resolve fundamental questions about adaptation, including its pace, temporal dynamics, and underlying phenotypic and genomic architecture. We tracked the evolu…
View article: <i>Drosophila</i> Evolution over Space and Time (DEST): A New Population Genomics Resource
<i>Drosophila</i> Evolution over Space and Time (DEST): A New Population Genomics Resource Open
Drosophila melanogaster is a leading model in population genetics and genomics, and a growing number of whole-genome data sets from natural populations of this species have been published over the last years. A major challenge is the integ…
View article: Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila Open
To advance our understanding of adaptation to temporally varying selection pressures, we identified signatures of seasonal adaptation occurring in parallel among Drosophila melanogaster populations. Specifically, we estimated allele freque…
View article: Author response: Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila
Author response: Broad geographic sampling reveals the shared basis and environmental correlates of seasonal adaptation in Drosophila Open
View article: No water, no mating: Connecting dots from behaviour to pathways
No water, no mating: Connecting dots from behaviour to pathways Open
Insects hold considerable ecological and agricultural importance making it vital to understand the factors impacting their reproductive output. Environmental stressors are examples of such factors which have a substantial and significant i…
View article: Allelic polymorphism at <i>foxo</i> contributes to local adaptation in <i>Drosophila melanogaster</i>
Allelic polymorphism at <i>foxo</i> contributes to local adaptation in <i>Drosophila melanogaster</i> Open
The insulin/insulin‐like growth factor signalling pathway has been hypothesized as a major determinant of life‐history profiles that vary adaptively in natural populations. In Drosophila melanogaster , multiple components of this pathway v…
View article: Direct observation of adaptive tracking on ecological timescales in<i>Drosophila</i>
Direct observation of adaptive tracking on ecological timescales in<i>Drosophila</i> Open
Direct observation of evolution in response to natural environmental change can resolve fundamental questions about adaptation including its pace, temporal dynamics, and underlying phenotypic and genomic architecture. We tracked evolution …
View article: Long Non-Coding RNAs in Insects
Long Non-Coding RNAs in Insects Open
Only a small subset of all the transcribed RNAs are used as a template for protein translation, whereas RNA molecules that are not translated play a very important role as regulatory non-coding RNAs (ncRNAs). Besides traditionally known RN…
View article: Accurate, ultra-low coverage genome reconstruction and association studies in Hybrid Swarm mapping populations
Accurate, ultra-low coverage genome reconstruction and association studies in Hybrid Swarm mapping populations Open
Genetic association studies seek to uncover the link between genotype and phenotype, and often utilize inbred reference panels as a replicable source of genetic variation. However, inbred reference panels can differ substantially from wild…
View article: <i>Drosophila</i> Evolution over Space and Time (DEST) - A New Population Genomics Resource
<i>Drosophila</i> Evolution over Space and Time (DEST) - A New Population Genomics Resource Open
Drosophila melanogaster is a leading model in population genetics and genomics, and a growing number of whole-genome datasets from natural populations of this species have been published over the last 20 years. A major challenge is the int…
View article: Post‐eclosion temperature effects on insect cuticular hydrocarbon profiles
Post‐eclosion temperature effects on insect cuticular hydrocarbon profiles Open
The insect cuticle is the interface between internal homeostasis and the often harsh external environment. Cuticular hydrocarbons (CHCs) are key constituents of this hard cuticle and are associated with a variety of functions including str…
View article: Cuticle darkening correlates with increased body copper content in Drosophila melanogaster
Cuticle darkening correlates with increased body copper content in Drosophila melanogaster Open
View article: Microbiome composition shapes rapid genomic adaptation of <i>Drosophila melanogaster</i>
Microbiome composition shapes rapid genomic adaptation of <i>Drosophila melanogaster</i> Open
Population genomic data has revealed patterns of genetic variation associated with adaptation in many taxa. Yet understanding the adaptive process that drives such patterns is challenging; it requires disentangling the ecological agents of…
View article: Accurate, ultra-low coverage genome reconstruction and association studies in Hybrid Swarm mapping populations
Accurate, ultra-low coverage genome reconstruction and association studies in Hybrid Swarm mapping populations Open
Genetic association studies seek to uncover the link between genotype and phenotype, and often utilize inbred reference panels as a replicable source of genetic variation. However, inbred reference panels can differ substantially from wild…
View article: A clinal polymorphism in the insulin signaling transcription factor <i>foxo</i> contributes to life‐history adaptation in <i>Drosophila</i> *
A clinal polymorphism in the insulin signaling transcription factor <i>foxo</i> contributes to life‐history adaptation in <i>Drosophila</i> * Open
A fundamental aim of adaptation genomics is to identify polymorphisms that underpin variation in fitness traits. In Drosophila melanogaster, latitudinal life-history clines exist on multiple continents and make an excellent system for diss…
View article: Microbiome composition shapes rapid genomic adaptation of<i>Drosophila melanogaster</i>
Microbiome composition shapes rapid genomic adaptation of<i>Drosophila melanogaster</i> Open
Population genomic data has revealed patterns of genetic variation associated with adaptation in many taxa. Yet understanding the adaptive process that drives such patterns is challenging - it requires disentangling the ecological agents o…
View article: Latitudinal Pigmentation Variation Contradicts Ultraviolet Radiation Exposure: A Case Study in Tropical Indian Drosophila melanogaster
Latitudinal Pigmentation Variation Contradicts Ultraviolet Radiation Exposure: A Case Study in Tropical Indian Drosophila melanogaster Open
The effects of ultraviolet radiation (UV) on the animal body have been reported in many studies, and melanin has emerged as a protective mechanism. In smaller insects such as Drosophila, replicated patterns of geographical variation…
View article: A clinal polymorphism in the insulin signaling transcription factor<i>foxo</i>contributes to life-history adaptation in<i>Drosophila</i>
A clinal polymorphism in the insulin signaling transcription factor<i>foxo</i>contributes to life-history adaptation in<i>Drosophila</i> Open
A fundamental aim of adaptation genomics is to identify polymorphisms that underpin variation in fitness traits. In D. melanogaster latitudinal life-history clines exist on multiple continents and make an excellent system for dissecting th…