Explanipedia

Comparable outcomes with low-dose and standard-dose horse anti-thymocyte globulin in the treatment of severe aplastic anemia Open

Arihant Jain, Aditya Jandial, Thenmozhi Mani, Kamal Kishore, Charanpreet Singh , et al. · 2024

Background The standard dose (SD) of horse anti-thymocyte globulin (hATG) ATGAM (Pfizer, USA) or its biosimilar thymogam (Bharat Serum, India) for the treatment of Aplastic Anemia (AA) is 40 mg/kg/day for 4 days in combination with cyclosp…

ALL-205 Deconvoluting and Characterizing the Newly Incorporated Genetic Subtypes and Treatment Outcomes of Acute Lymphoblastic Leukemia: A Report of 1,021 Indian Patients 5-Year Study Open

Dikshat Gopal Gupta, Neelam Varma, Mihai I. Truica, P. Tanwar, Sarki A. Abdulkadir , et al. · 2023

High-dose hydroxyurea with differentiating agents for treating ultra-high-risk acute promyelocytic leukemia in resource-challenged settings Open

Charanpreet Singh, Sarthak Wadhera, Uday Yanamandra, Parathan Karunakaran, Nishant Jindal , et al. · 2022

Successful Use of High Dose Methotrexate in Treatment of Primary CNS Lymphoma Patients Without Access to Serum Methotrexate Levels Monitoring: Challenges and Outcome Open

Charanpreet Singh, Arihant Jain, Aastha Takkar, Aniruddha Agarwal, Manish Rohilla , et al. · 2021

Efficacy, safety, and quality of life of generic and innovator ibrutinib in Indian CLL patients Open

Charanpreet Singh, Nishant Jindal, Padma Youron, Pankaj Malhotra, Gaurav Prakash , et al. · 2020

Variables affecting the presence of mesenchymal stromal cells in peripheral blood and their relationship with apheresis products Open

Ankur Jain, Alka Khadwal, Man Updesh Singh Sachdeva, Praveen Bose, Deepesh Lad , et al. · 2020

Summary Mesenchymal stromal cells (MSCs) demonstrate the properties of self‐renewal, multipotentiality, and immunosuppression, which are responsible for their widespread clinical applications in tissue repair and regeneration. MSCs have be…

Markers of Thrombin Generation and Inflammation in Patients with Paroxysmal Nocturnal Hemoglobinuria Open

Rishi Dhawan, Jasmina Ahluwalia, Pankaj Malhotra, Manoranjan Mahapatra, Neelam Varma , et al. · 2019

Clinical and hematological correlates of aberrant immunophenotypic profiles in adult and pediatric acute myeloid leukemia at presentation Open

Neelam Varma, Manupriya Sharma, ManUpdesh Singh Sachdeva, Parveen Bose, Subhash Varma · 2019

In summary, CD7 is the most common aberrant lymphoid antigen expressed in AML. FAB subtype AML-M3 is usually not associated with aberrant lymphoid antigen expression. AML cases with CD34 positivity are more likely to express aberrant lymph…

Patterns of geriatric anemia: A hospital-based observational study in North India Open

Dheeraj Sharma, Vikas Suri, Ashok Kumar Pannu, Savita Verma Attri, Neelam Varma , et al. · 2019

In most of the cases, anemia in the elderly had a treatable cause. Thus, a thorough investigation including gastrointestinal endoscopy is warranted. Unexplained progressive or unresponsive anemia requires bone marrow examination.

Multiple Granulocytic Sarcomas: A Rare Presentation of Acute Myeloid Leukemia Open

Kundan Mishra, Aditya Jandial, Yogendra Kumar, Deepesh Lad, Gaurav Prakash , et al. · 2018

A comparative study of 18F-FDG PET/CT with bilateral bone marrow trephine biopsy for assessment of bone marrow infiltration by lymphoma Open

Durairaj Arjunan, Gaurav Prakash, Pankaj Malhotra, Neelam Varma, Subhash Varma , et al. · 2018

Background: Bone marrow trephine biopsy (BMTB) is the gold standard test for identification of marrow infiltration by lymphoma. Literature supports the use of bilateral iliac crest biopsy for appropriate staging of lymphoma.18F-FDG PET/CT …

Impact of bisphosphonate and anti-myeloma therapy on bone turnover markers in multiple myeloma Open

Aditya Jandial, Senn Hj, Kundan Mishra, Sanjay Kumar Bhadada, Anil K. Sood , et al. · 2018

Background: Bone involvement is a defining feature of symptomatic multiple myeloma (MM). There is little information on changes in bone mineral metabolism that occur with bisphosphonates and anti-myeloma medication. Methods: Newly-diagnose…

Reduced Dose Ibrutinib Due to Financial Toxicity in CLL Open

Deepesh Lad, Pankaj Malhotra, Alka Khadwal, Gaurav Prakash, Arihant Jain , et al. · 2018

Anemia in celiac disease is multifactorial in etiology: A prospective study from India Open

Neha Berry, Jahangeer Basha, Neelam Varma, Subhash Varma, Kaushal Kishor Prasad , et al. · 2018

Background and Aims Anemia is one of the most common extraintestinal manifestations of celiac disease (CD), with iron deficiency anemia (IDA) being the predominant cause. However, anemia in CD can have varied etiologies, including mixed nu…

Isolated Splenic Cold Abscesses in an Immunocompetent Individual Open

Deba Prasad Dhibar, Bharath A Chhabria, Nanili Gupta, Subhash Varma · 2018

Tubercular splenic abscess is extremely rare, but are reported commonly in HIV-positive and immunocompromised patients along with miliary or disseminated tuberculosis. Isolated tubercular splenic abscess in an immunocompetent individual is…

Early detection of differentiation syndrome by chest ultrasound in acute promyelocytic leukaemia Open

Parathan Karunakaran, Uday Yanamandra, Ram Vasudevan Nampoothiri, Alka Khadwal, Gaurav Prakash , et al. · 2018

The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.

Balanitis in Acute Lymphoblastic Leukemia: A Rare Etiology and Unusual Presentation Open

Aditya Jandial, Kundan Mishra, Pradeep Tomar, Deepesh Lad, Gaurav Prakash , et al. · 2018

Danazol increases T regulatory cells in patients with aplastic anemia Open

Harshit Khurana, Pankaj Malhotra, Man Updesh Singh Sachdeva, Neelam Varma, Parveen Bose , et al. · 2018

We conclude that Danazol also leads to increase in T-regs in acquired idiopathic AA.

Necrotising Ulcerative Gingivitis: A Rare Manifestation of Pseudomonas Infection Open

Aditya Jandial, Kundan Mishra, Asharam Panda, Deepesh Lad, Gaurav Prakash , et al. · 2018

Primary pyomyositis in North India: a clinical, microbiological, and outcome study Open

Susheel Kumar, Ashish Bhalla, Rajveer Singh, Navneet Sharma, Aman Sharma , et al. · 2018

Primary pyomyositis is not an uncommon disease entity. Patients with comorbidities were more likely to receive initial inappropriate antibiotic therapy. Patients with positive pus culture report had the higher rate of complications. Lower …

A weeping ulcer that vanished with a ‘SMILE’ Open

Ankur Jain, Gaurav Prakash, Amanjit Bal, Pankaj Malhotra, Subhash Varma · 2018

Utility of CD200 expression and CD20 antibody binding capacity in differentiating chronic lymphocytic leukemia from other chronic lymphoproliferative disorders Open

Neelam Varma, Raju Poongodi, Shano Naseem, Parveen Bose, Subhash Varma · 2018

Our results support the fact that CD200 can be added to routine CLPD panel as it is useful in subcategorizing them. However, inclusion of CD20 ABC to routine panel does not seem plausible but may be done for difficult diagnostic cases or w…

Invasive Fungal Infections in Acute Promyelocytic Leukemia on Dual Differentiating Agents: Real World Data Open

Uday Yanamandra, Parathan Karunakaran, Alka Khadwal, Gaurav Prakash, Deepesh Lad , et al. · 2017

“Everything that Glows on PET is not Lymphoma”: An Unheralded Intruder in a Case of Diffuse Large B Cell Lymphoma Open

Aditya Jandial, Uma Nahar Saikia, Kundan Mishra, Mayur Parkhi, Yogendra Kumar , et al. · 2017

Infusion Related Hypersensitivity Reactions with Bio-similar Anti CD-20 Monoclonal Antibody Rituximab in Indian Patients: A Retrospective Study Open

Gaurav Prakash, Pankaj Malhotra, Alka Khadwal, Deepesh Lad, Vikas Suri , et al. · 2017

Acquired Hemophilia A: Experience of a Tertiary Care Institute from North India Open

Narender Kumar, Sweta Rajpal, Jasmina Ahluwalia, Sunil Bose, Varun Uppal , et al. · 2017

Analysis of Clinical Profile and Outcome of Tuberculosis in Patients with Acute Leukemia Open

Arihant Jain, Gaurav Prakash, Charanpreet Singh, Deepesh Lad, Alka Khadwal , et al. · 2017

Complications and management of coagulation disorders in leukemia patients Open

Deepesh Lad, Arihant Jain, Subhash Varma · 2017

Patients with leukemia are predisposed to various coagulation abnormalities. Thrombosis and bleeding continue to be a major cause of morbidity and mortality in leukemias. The pathophysiology of these disorders is unique, and not only the d…

Verrucous Skin Lesions in a Case of Acute Lymphoblastic Leukemia: A Rare Manifestation of Cytomegalovirus Infection Open

Kundan Mishra, Aditya Jandial, Amanjit Bal, Garima Dabas, Nishant Jindal , et al. · 2017

Cost of Treatment of Multiple Myeloma in a Public Sector Tertiary Care Hospital of North India Open

Gunjeet Kaur, Shankar Prinja, Pankaj Malhotra, Deepesh Lad, Gaurav Prakash , et al. · 2017

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