Subhash Yadav
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View article: Sustainable Patient Education in Urology: Evaluating Quick Response (QR) Code-Based Information Delivery
Sustainable Patient Education in Urology: Evaluating Quick Response (QR) Code-Based Information Delivery Open
Background Clear communication and effective dissemination of information remain the mainstay of any clinical appointment. This allows the clinician and the patient to formulate a management plan with informed consent from the patient. The…
View article: Visceral Leishmaniasis without Splenomegaly – Atypical presentation
Visceral Leishmaniasis without Splenomegaly – Atypical presentation Open
Visceral leishmaniasis (kala-azar) is caused by a protozoan parasite of genus Leishmania. India and neighboring countries comprise the largest focus of VL. Moderate to higher degree of fever accompanied by rigor and hepatosplenomegaly is t…
View article: PReCedeNT trial: Phase III randomized-controlled trial of Lutetium − 177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) plus Chemotherapy versus PRRT alone in FDG-avid, Well-differentiated Gastroenteropancreatic neuroendocrine tumors (GEP-NETs)
PReCedeNT trial: Phase III randomized-controlled trial of Lutetium − 177 DOTATATE Peptide Receptor Radionuclide Therapy (PRRT) plus Chemotherapy versus PRRT alone in FDG-avid, Well-differentiated Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) Open
View article: Undifferentiated Carcinoma With Osteoclast-like Giant Cells of the Pancreaticobiliary Tract: A Single Tertiary-Care-Oncology Center Case Series
Undifferentiated Carcinoma With Osteoclast-like Giant Cells of the Pancreaticobiliary Tract: A Single Tertiary-Care-Oncology Center Case Series Open
Context. Undifferentiated carcinomas with osteoclast-like giant cells of the pancreaticobiliary tract (UCOGCs) are rare but distinctive tumors with limited literature. Objective. To study the clinicopathologic characteristics of UCOGCs inc…
View article: Imaging of Pelvic Floor Dysfunction
Imaging of Pelvic Floor Dysfunction Open
The pelvic floor, which is divided into anterior, middle, and posterior compartments, receives support from muscles, endopelvic fascia, and ligaments that support the pelvic organs and prevent organ prolapse. Deficiency in the musculofasci…
View article: Scrotal metastasis of colorectal carcinoma with unusual presentation and late recurrences: A study from a tertiary care oncology center in India
Scrotal metastasis of colorectal carcinoma with unusual presentation and late recurrences: A study from a tertiary care oncology center in India Open
Background: Colorectal carcinoma (CRC) is a common malignancy, frequently metastasizing to the liver, lungs, and regional lymph nodes. However, metastasis to the scrotum is exceedingly rare, with few cases reported in the literature. In th…
View article: Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal Cancer
Response Assessment after Neoadjuvant Chemoradiotherapy in Rectal Cancer Open
Management of locally advanced rectal cancer is complex, and magnetic resonance imaging (MRI) findings play a central role in treatment decisions. While neoadjuvant chemoradiotherapy significantly improved local recurrence rates, newer tre…
View article: Effect of the radioprotector chlorophyllin on graft versus leukemia response in experimental allogeneic hematopoietic stem cell transplantation
Effect of the radioprotector chlorophyllin on graft versus leukemia response in experimental allogeneic hematopoietic stem cell transplantation Open
View article: Effect of Biochar and Bio-inoculants on Yield, Nutrient Content and Uptake of Mungbean
Effect of Biochar and Bio-inoculants on Yield, Nutrient Content and Uptake of Mungbean Open
A field experiment was conducted to study the effect of biochar and bio-inoculants on yield attributes and yield of mungbean, and to assess the impact of biochar and bio-inoculants on nutrient content and uptake by mungbean during Kharif 2…
View article: 169TiP Colorectal carcinoma: Low dose immunotherapy in upfront metastatic d/MMR patients (CLOUD study)
169TiP Colorectal carcinoma: Low dose immunotherapy in upfront metastatic d/MMR patients (CLOUD study) Open
View article: IMPROVE: Improving Medical Plausibility without Reliance on HumanValidation -- An Enhanced Prototype-Guided Diffusion Framework
IMPROVE: Improving Medical Plausibility without Reliance on HumanValidation -- An Enhanced Prototype-Guided Diffusion Framework Open
Generative models have proven to be very effective in generating synthetic medical images and find applications in downstream tasks such as enhancing rare disease datasets, long-tailed dataset augmentation, and scaling machine learning alg…
View article: Classification and Morphological Analysis of DLBCL Subtypes in H\&E-Stained Slides
Classification and Morphological Analysis of DLBCL Subtypes in H\&E-Stained Slides Open
We address the challenge of automated classification of diffuse large B-cell lymphoma (DLBCL) into its two primary subtypes: activated B-cell-like (ABC) and germinal center B-cell-like (GCB). Accurate classification between these subtypes …
View article: High-Grade Gastrointestinal Neuroendocrine Carcinomas: Multidisciplinary Approach Can Improve Survival Outcomes
High-Grade Gastrointestinal Neuroendocrine Carcinomas: Multidisciplinary Approach Can Improve Survival Outcomes Open
Purpose There is limited evidence for the presentation patterns and outcomes of patients with high-grade gastrointestinal neuroendocrine carcinomas (HG-NEC). Methods Patients diagnosed with HG-NEC, defined as having a pathological diagnosi…
View article: Statins attenuate Wnt/β-catenin signaling by targeting SATB family proteins in colorectal cancer
Statins attenuate Wnt/β-catenin signaling by targeting SATB family proteins in colorectal cancer Open
Colorectal cancer is the second leading cause of cancer-related deaths worldwide, highlighting the need for improved treatments and advanced molecular research. A recent therapeutic approach focuses on repurposing drugs to target dysregula…
View article: Phase <scp>III</scp> randomized trial comparing palliative systemic therapy to best supportive care in advanced esophageal/<scp>GEJ</scp> cancer
Phase <span>III</span> randomized trial comparing palliative systemic therapy to best supportive care in advanced esophageal/<span>GEJ</span> cancer Open
No study has unequivocally proven that chemotherapy prolongs overall survival (OS) in advanced esophageal cancer. We conducted a Phase III randomized study in first‐line advanced unresectable/metastatic esophageal/GEJ cancer. Patients aged…
View article: Performance of Low-Dose Immunotherapy and Standard-Dose Immunotherapy in Microsatellite Instability-High Metastatic Colorectal Cancer: Real-World Data (CLouD—High Study)
Performance of Low-Dose Immunotherapy and Standard-Dose Immunotherapy in Microsatellite Instability-High Metastatic Colorectal Cancer: Real-World Data (CLouD—High Study) Open
PURPOSE Standard-dose immune checkpoint inhibitors (SD-ICIs) are the standard of care as initial therapy in microsatellite instable-high (MSI-H) advanced/metastatic colorectal adenocarcinomas (mCRC), but there are preclinical data to sugge…
View article: Correction: Deep learning based automated epidermal growth factor receptor and anaplastic lymphoma kinase status prediction of brain metastasis in non-small cell lung cancer
Correction: Deep learning based automated epidermal growth factor receptor and anaplastic lymphoma kinase status prediction of brain metastasis in non-small cell lung cancer Open
[This corrects the article DOI: 10.37349/etat.2023.00158.].
View article: Desmoid Fibromatosis of the Oesophagus Creating an Oesophageal Diverticulum in a 2-year-old Girl
Desmoid Fibromatosis of the Oesophagus Creating an Oesophageal Diverticulum in a 2-year-old Girl Open
Extra-abdominal desmoid fibromatosis arising from the oesophagus and the contemporaneous traction diverticula due to an oesophageal tumour is extremely rare. We present this complex situation in a 2-year-old girl which posed a surgical cha…
View article: Spindle Cell Lipoma and Pleomorphic Lipoma in the Head and Neck: A Comprehensive Study of Six Cases With Review of Literature
Spindle Cell Lipoma and Pleomorphic Lipoma in the Head and Neck: A Comprehensive Study of Six Cases With Review of Literature Open
SLs are a rare and uncommon variant of lipoma with a predilection in the head and neck region. They are low-grade neoplasms with a propensity to recur after years. Having knowledge of this tumor can improve surgical outcomes and better pat…
View article: Stubborn Swellings: A Rare Case of Kimura’s Disease Presenting as Parotid Swellings
Stubborn Swellings: A Rare Case of Kimura’s Disease Presenting as Parotid Swellings Open
View article: TB-free Ebeye: Results from integrated TB and noncommunicable disease case finding in Ebeye, Marshall Islands
TB-free Ebeye: Results from integrated TB and noncommunicable disease case finding in Ebeye, Marshall Islands Open
View article: Colorectal Carcinoma metastasizing to Scrotum: A series of five cases with unusual presentation and late recurrences from a single tertiary oncology centre of India
Colorectal Carcinoma metastasizing to Scrotum: A series of five cases with unusual presentation and late recurrences from a single tertiary oncology centre of India Open
Background Colorectal carcinoma (CRC) is a common malignancy, frequently metastasizing to the liver, lungs, and regional lymph nodes. However, metastasis to the scrotum is exceedingly rare, with few cases reported in the literature. In thi…
View article: <i>Withania Somnifera</i> Extract Mitigates Experimental Acute Graft versus Host Disease Without Abrogating Graft Versus Leukemia Effect
<i>Withania Somnifera</i> Extract Mitigates Experimental Acute Graft versus Host Disease Without Abrogating Graft Versus Leukemia Effect Open
Acute graft versus host disease (aGvHD) is the major contributor of nonrelapse mortality in alloHSCT. It is associated with an inflammatory immune response manifesting as cytokine storm with ensuing damage to target organs such as liver, g…
View article: Differentiation of Discordant Lesions on Dual-Tracer PET/CT (<sup>68</sup>Ga-PSMA-11 and<sup>18</sup>F-FDG) in Prostate Carcinoma: Diagnosis of Second Primary Malignancies
Differentiation of Discordant Lesions on Dual-Tracer PET/CT (<sup>68</sup>Ga-PSMA-11 and<sup>18</sup>F-FDG) in Prostate Carcinoma: Diagnosis of Second Primary Malignancies Open
We present 2 cases of metastatic castration-resistant prostate carcinoma with discordant lesions on dual-tracer PET/CT (68Ga-PSMA-11 and 18F-FDG PET/CT), which on subsequent histopathologic evaluation revealed second …
View article: Intratumoural metastasis of primary lung adenocarcinoma to non-invasive follicular thyroid neoplasm with papillary-like nuclear features
Intratumoural metastasis of primary lung adenocarcinoma to non-invasive follicular thyroid neoplasm with papillary-like nuclear features Open
Metastasis to the thyroid gland is very uncommon with an incidence of 2-3% of all thyroid malignancies. A higher incidence is noted in autopsy studies indicating incidental detection. However, tumour-to-tumour metastasis is extremely uncom…
View article: Imaging Recommendations for Diagnosis, Staging, and Management of Peritoneal Malignancies
Imaging Recommendations for Diagnosis, Staging, and Management of Peritoneal Malignancies Open
Peritoneum is a serosal membrane lining the solid viscera and the hollow viscus of the abdomen and is made of a single layer of mesothelial cells. The most common primaries that spread to the peritoneum include gastrointestinal, ovarian, c…
View article: Erdafitinib for tumors with FGFR3 mutation: A promising targeted therapy
Erdafitinib for tumors with FGFR3 mutation: A promising targeted therapy Open
CASE SUMMARY History and examination A 77-year-old gentleman, with no prior comorbidities or a family history of malignancy, presented in October 2021 to the outpatient department of the Tata Memorial Hospital, Mumbai, India, with complain…
View article: Nonsalivary Primary Adenocarcinomas of the Base of the Tongue: A Single Tertiary-Care Oncology Center Series of 6 Cases
Nonsalivary Primary Adenocarcinomas of the Base of the Tongue: A Single Tertiary-Care Oncology Center Series of 6 Cases Open
Context.— Nonsalivary primary adenocarcinomas of the base of the tongue (PABOTs) are extremely rare and worth reporting. Objective.— To study the detailed clinicopathologic features of PABOT. Design.— Cases of PABOT diagnosed on pathology …
View article: Validation of Remote Digital Pathology based diagnostic reporting of Frozen Sections from home
Validation of Remote Digital Pathology based diagnostic reporting of Frozen Sections from home Open
This study validates the role of WSI for remote FS diagnosis for its safe and efficient adoption in clinical use.
View article: Efficient quality control of whole slide pathology images with human-in-the-loop training
Efficient quality control of whole slide pathology images with human-in-the-loop training Open