Sudeep Joshi
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View article: Imaging-guided platform for real-time intervention in complex in vitro models
Imaging-guided platform for real-time intervention in complex in vitro models Open
Complex in vitro models (CIVMs), including organoids, spheroids, and bioprinted constructs, have emerged as powerful platforms for recapitulating human tissue architecture and function. However, their inherent heterogeneity and dynamic nat…
View article: Multimodal profiling unveils a reversible breast basal-like cell state in AKT-inhibitor resistant tumours
Multimodal profiling unveils a reversible breast basal-like cell state in AKT-inhibitor resistant tumours Open
The PI3K/AKT/mTOR pathway is central to cell metabolism and growth. However, pharmacological inhibition of the pathway is not uniformly effective across cancer types, or even within a single cancer model. In this study, we leverage oblique…
View article: Low-cost, versatile, and highly reproducible microfabrication pipeline to generate 3D-printed customised cell culture devices with complex designs
Low-cost, versatile, and highly reproducible microfabrication pipeline to generate 3D-printed customised cell culture devices with complex designs Open
Cell culture devices, such as microwells and microfluidic chips, are designed to increase the complexity of cell-based models while retaining control over culture conditions and have become indispensable platforms for biological systems mo…
View article: SOL3D: Soft-lithography on 3D vat polymerised moulds for fast, versatile, and accessible high-resolution fabrication of customised multiscale cell culture devices with complex designs
SOL3D: Soft-lithography on 3D vat polymerised moulds for fast, versatile, and accessible high-resolution fabrication of customised multiscale cell culture devices with complex designs Open
Cell culture devices, such as microwells and microfluidic chips, are designed to increase the complexity of cell-based models whilst retaining control over culture conditions and have become indispensable platforms for biological systems m…
View article: A 3D‐Printed Hybrid Nasal Cartilage with Functional Electronic Olfaction
A 3D‐Printed Hybrid Nasal Cartilage with Functional Electronic Olfaction Open
Advances in biomanufacturing techniques have opened the doors to recapitulate human sensory organs such as the nose and ear in vitro with adequate levels of functionality. Such advancements have enabled simultaneous targeting of two challe…