Sudeep Shrestha
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View article: Exploring maternal healthcare services and child feeding practices in Nepal: A scoping review
Exploring maternal healthcare services and child feeding practices in Nepal: A scoping review Open
Background: Maternal healthcare services (MHS) include antenatal care (ANC), natal and postnatal care (PNC). Women engage with healthcare providers for self-care throughout the antenatal, natal and postnatal periods and receive guidance on…
View article: Budget and Schedule-Related Critical Success Factors for Design-Build Water and Wastewater Projects: Principal Component Analysis
Budget and Schedule-Related Critical Success Factors for Design-Build Water and Wastewater Projects: Principal Component Analysis Open
The United States confronts significant challenges within the water and wastewater sectors. According to the American Water Works Association (AWWA), a capital investment of $1.3 trillion is necessary for the repair and replacement of wate…
View article: A rare case of symmetric quadriplegia in a patient with Japanese encephalitis: a case report
A rare case of symmetric quadriplegia in a patient with Japanese encephalitis: a case report Open
Introduction and importance: Acute flaccid paralysis is a rare neurological complication of Japanese encephalitis (JE) infection, which may involve one or multiple limbs. Symmetric involvement of upper and lower limbs such as in this case …
View article: Prospective Association of Symptoms of Depression and Anxiety with Pornography Viewing Frequency Among Young Adults
Prospective Association of Symptoms of Depression and Anxiety with Pornography Viewing Frequency Among Young Adults Open
View article: Author Correction: Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation
Author Correction: Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation Open
View article: Navigating a Pandemic: A Qualitative Study of Knowledge, Sources of Information, and COVID-19-Related Precautions Taken by HBCU Students
Navigating a Pandemic: A Qualitative Study of Knowledge, Sources of Information, and COVID-19-Related Precautions Taken by HBCU Students Open
View article: Empirical Anthelmintic Therapy for Patients with Eosinophilia in Nepal: A Prospective Cohort Study
Empirical Anthelmintic Therapy for Patients with Eosinophilia in Nepal: A Prospective Cohort Study Open
Eosinophilia is common in low-resource countries and usually implies helminthiasis. Since helminthiasis is a common cause of eosinophilia and its diagnosis is cumbersome, we hypothesized that broad-spectrum anthelmintic therapy may decreas…
View article: Retinal Haemorrhage in Newborns in Tertiary Care Hospital
Retinal Haemorrhage in Newborns in Tertiary Care Hospital Open
Background Retinal haemorrhage in new-born is a clinically common neonatal fundus condition. Although, it usually does not affect the development of visual function, entities like macular haemorrhages may lead to amblyopia causing deterior…
View article: Study on Patient’s Perception on Medication Counseling at Community Pharmacy in Sub-urban Area of Nepal
Study on Patient’s Perception on Medication Counseling at Community Pharmacy in Sub-urban Area of Nepal Open
Background Community pharmacists are the primary contact point in a healthcare system who provide medication information to the patients and enable them to make appropriate decision regarding their therapy. Hence, this study explored patie…
View article: Drug Utilization Study in Outpatient Department of Ophthalmology in Tertiary Care Hospital
Drug Utilization Study in Outpatient Department of Ophthalmology in Tertiary Care Hospital Open
Background The advancement in drug development and availability of newer drugs has improved overall health services including decrease in mortality and hospital stay. Along, it has brought negative impacts such as polypharmacy and associat…
View article: An audit of patients admitted to hospital in Nepal for COPD exacerbation
An audit of patients admitted to hospital in Nepal for COPD exacerbation Open
Objectives: Chronic obstructive pulmonary disease is a large and increasing problem in low- and middle-income countries; Nepal is no exception. We aimed to obtain information on patient characteristics and the level of care provided to pat…
View article: Predictors of Mortality in COVID-19-Positive Patients On and Off CPAP: A Review From a Tertiary Care Setting in the NHS
Predictors of Mortality in COVID-19-Positive Patients On and Off CPAP: A Review From a Tertiary Care Setting in the NHS Open
View article: Incidence of healthcare-associated infections with invasive devices and surgical procedures in Nepal
Incidence of healthcare-associated infections with invasive devices and surgical procedures in Nepal Open
SETTING: Dhulikhel Hospital, Kathmandu University Hospital, Kathmandu, Nepal. OBJECTIVES: 1) To report the incidence of health-care-associated infections (HAIs), 2) to compare demographic, clinical characteristics and hospital outcomes in …
View article: Surgical antibiotic prophylaxis administration practices
Surgical antibiotic prophylaxis administration practices Open
SETTING: A referral hospital in Kavre, Nepal. OBJECTIVES: To assess 1) compliance with National Antibiotic Treatment Guidelines (NATG), specifically, whether the administration of surgical antibiotic prophylaxis (SAP) (initial dosing and r…
View article: TARGET JNL: Neuropsychiatric Disease and Treatment Clinically Significant Changes in the 17- and 6-Item Hamilton Rating Scales for Depression: A STAR*D Report
TARGET JNL: Neuropsychiatric Disease and Treatment Clinically Significant Changes in the 17- and 6-Item Hamilton Rating Scales for Depression: A STAR*D Report Open
Augustus John Rush, 1– 3 Charles South, 4 Shailesh Jain, 1 Raafae Agha, 1 Mingxu Zhang, 1 Shristi Shrestha, 1 Zershana Khan, 1 Mudasar Hassan, 1 Madhukar H Trivedi 5 1Department of Psychiatry, Texas Tech University Health Science Center, M…
View article: Comparative Efficacy and Safety of Diacerein in Patients with Knee Osteoarthritis: A Pilot Study
Comparative Efficacy and Safety of Diacerein in Patients with Knee Osteoarthritis: A Pilot Study Open
Background Osteoarthritis (OA) is the most common chronic rheumatic disease. The prevalence of OA is skyrocketing with time. Providing a proper treatment regimen for OA is also growing as a major public health challenge. Conventional pharm…
View article: Oral Cysticercosis Presenting as an Innocuous Lesion.
Oral Cysticercosis Presenting as an Innocuous Lesion. Open
Cysticercosis is a parasitic infection with potential of causing significant morbidity especially in developing countries. The larval form of the parasite Taenia Solium, 'Cysticercus Cellulosae' primarily colonizes in the small intestine a…
View article: Virological and Immunological Status of the People Living with HIV Undertaking Highly Active Antiretroviral Therapy.
Virological and Immunological Status of the People Living with HIV Undertaking Highly Active Antiretroviral Therapy. Open
Background The major goal of antiretroviral therapy (ART) is immunological recovery and virological suppression. Immunological and virological response in People Living with HIV (PLHIV) undertaking ART has to be monitored to assess the tre…
View article: Adherence to Iron, Folic Acid and Calcium Supplement and Factors Affecting it among the Antenatal Care Attending Women in a Tertiary Care Hospital: A Cross Sectional Study
Adherence to Iron, Folic Acid and Calcium Supplement and Factors Affecting it among the Antenatal Care Attending Women in a Tertiary Care Hospital: A Cross Sectional Study Open
Background Pregnancy or gestation is the time during which a single or more children grows and develops inside a woman. Antenatal care improves the pregnancy outcomes under which a group of medication i.e. iron, folic acid and calcium are …
View article: Hormonal Contraceptives Use and Their Adverse Effects: A Cross-sectional Study among the Women Visiting Tertiary Care Center
Hormonal Contraceptives Use and Their Adverse Effects: A Cross-sectional Study among the Women Visiting Tertiary Care Center Open
Background Hormonal contraceptives are one of the most commonly used means of contraception. Lack of contraception may lead to large family size, increased preexisting illness on pregnancy, social and economic instability, risk of unsafe a…
View article: Analysis of Antimicrobial Drugs Usage Pattern and it’s Cost Analysis in the Pediatric Department of a Tertiary Care Hospital
Analysis of Antimicrobial Drugs Usage Pattern and it’s Cost Analysis in the Pediatric Department of a Tertiary Care Hospital Open
Background Antimicrobials agents are the most widely and often imprudently used therapeutic drugs globally. The pediatric population comprises 20-25% of the total world population, and various acute and chronic diseases are prone to this g…
View article: Evaluation of inhalation technique in patients using a dry powder device (DPI) at chest clinic in Dhulikhel Hospital – Kathmandu University Hospital, and the effect of patient education on it
Evaluation of inhalation technique in patients using a dry powder device (DPI) at chest clinic in Dhulikhel Hospital – Kathmandu University Hospital, and the effect of patient education on it Open
The mainstay of chronic obstructive pulmonary disorder (COPD), asthma and asthma-COPD overlap syndrome (ACOS) treatment is by inhalational medication(s). Delivery of drugs directly into the airways, achieving higher local concentrations wi…
View article: Evaluation of inhalation technique in patients using a dry powder device (DPI) at chest clinic in Dhulikhel Hospital – Kathmandu University Hospital, and the effect of patient education on it
Evaluation of inhalation technique in patients using a dry powder device (DPI) at chest clinic in Dhulikhel Hospital – Kathmandu University Hospital, and the effect of patient education on it Open
The mainstay of chronic obstructive pulmonary disorder (COPD), asthma and asthma-COPD overlap syndrome (ACOS) treatment is by inhalational medication(s). Delivery of drugs directly into the airways, achieving higher local concentrations wi…
View article: Open label comparative trial of mono versus dual antibiotic therapy for Typhoid Fever in adults
Open label comparative trial of mono versus dual antibiotic therapy for Typhoid Fever in adults Open
Trial registration number: NCT02224040.
View article: Typhoid Fever: Combined vs. Single Antibiotic Therapy v1
Typhoid Fever: Combined vs. Single Antibiotic Therapy v1 Open
Typhoid Fever: Combined vs. Single Antibiotic Therapy
View article: Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation
Melatonin-mediated mitophagy protects against early brain injury after subarachnoid hemorrhage through inhibition of NLRP3 inflammasome activation Open
View article: Study on Corticosteroids use Pattern in Dermatological Practice and Investigating Adverse Effect of Corticosteroids Including its Associated Factors
Study on Corticosteroids use Pattern in Dermatological Practice and Investigating Adverse Effect of Corticosteroids Including its Associated Factors Open
Background Corticosteroids are highly effective drugs with anti-inflammatory and immunosuppressive properties. Due to this, they have become a mainstay of pharmacotherapy in dermatology. However, improper and long term uses are associated …
View article: Study of Pre-disposing Factors of Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Antibiotic Prescribing Pattern with Reference to Antibiotic Sensitivity Test
Study of Pre-disposing Factors of Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Antibiotic Prescribing Pattern with Reference to Antibiotic Sensitivity Test Open
Background Chronic Obstructive Pulmonary Disease (COPD) affects about 329 million people worldwide, which is nearly 5% of the entire global population. In the context of Nepal, COPD accounts for 43% of the non-communicable disease burden a…
View article: A predicted model for postoperative seizure outcomes after the surgical resection of supratentorial cavernous malformations
A predicted model for postoperative seizure outcomes after the surgical resection of supratentorial cavernous malformations Open
To explore a predicted model for postoperative seizure outcomes after the surgical resection of supratentorial cavernous malformations.This study was a retrospective review of consecutive patients with cerebral supratentorial cavernous mal…
View article: Photo-onycholysis Following Two Weeks of Doxycycline.
Photo-onycholysis Following Two Weeks of Doxycycline. Open
Photo-onycholysis is a form of phototoxic reaction characterized by spontaneous separation of the nail plate from the nail bed. It usually follows drug intake and tetracycline is a well-known culprit. We present a case of 19 years gentlema…