Jen‐Sue Chen
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View article: HDAC1 dysregulation promotes pro-inflammatory microglial activation and aggravates post-stroke neuroinflammation
HDAC1 dysregulation promotes pro-inflammatory microglial activation and aggravates post-stroke neuroinflammation Open
HDAC1 acts as a key repressor of NF-κB-driven pro-inflammatory microglial activation and neuroinflammation in stroke. Its loss exacerbates inflammatory cascades, immune cell infiltration, and neuronal injury, underscoring HDAC1 as a potent…
View article: Thermally Activated Negative Differential Resistance VO <sub> <i>x</i> </sub> Memristor with Switchable Rate and Leaky Integrate-and-Fire Spiking Dynamics
Thermally Activated Negative Differential Resistance VO <sub> <i>x</i> </sub> Memristor with Switchable Rate and Leaky Integrate-and-Fire Spiking Dynamics Open
Spiking neural networks (SNNs) require neuron devices that are both compact and capable of supporting continuous-time and event-based dynamics. Here, we demonstrate a VOx-based threshold switching memristor (TSM) that intrinsically enables…
View article: All HfO<sub><i>x</i></sub>-Resistive Switches with the Conducting Oxygen Vacancy Exchange Layer and Self-Limited Oxide Layer
All HfO<sub><i>x</i></sub>-Resistive Switches with the Conducting Oxygen Vacancy Exchange Layer and Self-Limited Oxide Layer Open
Resistive random-access memory based on hafnia is a potential candidate for next-generation memories. However, there are some key challenges to overcome, including the stochastic nature of the filament formation during electroforming and S…
View article: Mitochondrial-dependent apoptosis and STAT3 activation induced by oxidative stress in pemphigus vulgaris
Mitochondrial-dependent apoptosis and STAT3 activation induced by oxidative stress in pemphigus vulgaris Open
In the context of Pemphigus Vulgaris (PV), an autoimmune skin disorder, our study explores the intricate relationship between dyslipidemia, oxidative stress, and mitochondrial-dependent apoptosis in PV. We investigated lipid profiles in PV…
View article: COS2A: Conversion from Sentinel-2 to AVIRIS Hyperspectral Data Using Interpretable Algorithm With Spectral-Spatial Duality
COS2A: Conversion from Sentinel-2 to AVIRIS Hyperspectral Data Using Interpretable Algorithm With Spectral-Spatial Duality Open
The Sentinel-2 satellite, launched by the European Space Agency (ESA), offers extensive spatial coverage and has become indispensable in a wide range of remote sensing applications. However, it just has 12 spectral bands, making substances…
View article: The Applications of Anchoring Effect in Business Activities
The Applications of Anchoring Effect in Business Activities Open
The anchoring effect is an important theory in behavioral economics, which has aroused much attention and been widely utilized in the economic market. By far, much research and experiments have been done to show the mechanism, types and ap…
View article: Interfacial Electronic Charge Trapping and Photonic Carrier Excitation Coupling in Solution-Processed Zinc–Tin Oxide Thin-Film Transistors Applied for Logic Gate Design and Quantized Neural Network
Interfacial Electronic Charge Trapping and Photonic Carrier Excitation Coupling in Solution-Processed Zinc–Tin Oxide Thin-Film Transistors Applied for Logic Gate Design and Quantized Neural Network Open
Components needed in Artificial Intelligence with a higher information capacity are critically needed and have garnered significant attention at the forefront of information technology. This study utilizes solution-processed zinc-tin oxide…
View article: Light‐to‐Spike Encoding Using Indium‐Gallium‐Zinc Oxide Phototransistor for all‐Color Image Recognition with Dynamic Range and Precision Tunability
Light‐to‐Spike Encoding Using Indium‐Gallium‐Zinc Oxide Phototransistor for all‐Color Image Recognition with Dynamic Range and Precision Tunability Open
To enhance the efficiency of machine vision system, physical hardware capable of sensing and encoding is essential. However, sensing and encoding color information has been overlooked. Therefore, this work utilizes an indium‐gallium‐zinc o…
View article: Achieving neuronal dynamics with spike encoding and spatial-temporal summation in vanadium-based threshold switching memristor for asynchronous signal integration
Achieving neuronal dynamics with spike encoding and spatial-temporal summation in vanadium-based threshold switching memristor for asynchronous signal integration Open
This work features a vanadium-based threshold switching memristor with spatial-temporal and spiking encoding capabilities, offering a prospect for the hardware realization of spiking neural networks.
View article: Cholinesterase Inhibitor Reveals Synergistic Potential for Neural Stem Cell-Based Therapy in the 5xFAD Mouse Model of Alzheimer’s Disease
Cholinesterase Inhibitor Reveals Synergistic Potential for Neural Stem Cell-Based Therapy in the 5xFAD Mouse Model of Alzheimer’s Disease Open
Combining ChEIs with NSC transplantation produces synergistic effects in AD treatment. This approach highlights the potential of integrating these therapies to develop more effective strategies for managing Alzheimer's disease.
View article: Endosomes serve as signaling platforms for RIG-I ubiquitination and activation
Endosomes serve as signaling platforms for RIG-I ubiquitination and activation Open
RIG-I–like receptors (RLRs) are cytosolic RNA sensors critical for antiviral immunity. RLR activation is regulated by polyubiquitination and oligomerization following RNA binding. Yet, little is known about how RLRs exploit subcellular org…
View article: Metal oxide thin film electronics
Metal oxide thin film electronics Open
Metal oxides, once a scientific curiosity, 1 have evolved into a transformative technology for modern electronics. 24][5][6][7] The ability of metal oxides to deliver semiconducting channels in thin-film transistors (TFTs) over large-area …
View article: Harness Background Lighting for Separability Enhancement in Optical Sensing Reservoir for Temporal Signal Processing Utilizing Amorphous IGZO Neuromorphic Transistors
Harness Background Lighting for Separability Enhancement in Optical Sensing Reservoir for Temporal Signal Processing Utilizing Amorphous IGZO Neuromorphic Transistors Open
By drawing inspiration from the human visual system, utilizing optoelectronic devices for processing temporal and unstructured data within an in-sensor reservoir (RC) has gained increasing attention in the field of advanced machine vision …
View article: Unveiling transient current response in bilayer oxide-based physical reservoirs for time-series data analysis
Unveiling transient current response in bilayer oxide-based physical reservoirs for time-series data analysis Open
The proposed memristive device showcases nonlinear current responses and short-term memory behaviors, perfectly functioning as a physical reservoir with the capability to segregate 4-bit input signals and diverse temporal patterns.
View article: Emulating Nociceptive Receptor and LIF Neuron Behavior via ZrO<sub>x</sub>‐based Threshold Switching Memristor
Emulating Nociceptive Receptor and LIF Neuron Behavior via ZrO<sub>x</sub>‐based Threshold Switching Memristor Open
For the progress of artificial neural networks, the imitation of multiple biological functions is indispensable for processing more tasks in a complex working environment. Memristors, which possess these advantages such as uniformity, high…
View article: LumbarNet: A Deep Learning Network for the Automated Detection of Lumbar Spondylolisthesis From X-Ray Images
LumbarNet: A Deep Learning Network for the Automated Detection of Lumbar Spondylolisthesis From X-Ray Images Open
A common spinal condition, spondylolisthesis is the presence of a relative back or forth displacement between the upper and lower vertebra due to one vertebra being oriented away from the smooth curvature of a normal spine. Aging-related i…
View article: Halide perovskite for low‐power consumption neuromorphic devices
Halide perovskite for low‐power consumption neuromorphic devices Open
The rapid emergency of data science, information technology, and artificial intelligence (AI) relies on massive data processing with high computing efficiency and low power consumption. However, the current von‐Neumann architecture system …
View article: Violet-light stimulated synaptic and learning functions in a zinc–tin oxide photoelectric transistor for neuromorphic computation
Violet-light stimulated synaptic and learning functions in a zinc–tin oxide photoelectric transistor for neuromorphic computation Open
Photonic potentiation and electric depression are realized in a ZTO thin film transistor for the application in neuromorphic computation.
View article: Extraction of sub-gap density of states via capacitance–voltage measurement for the erasing process in a TFT charge-trapping memory
Extraction of sub-gap density of states via capacitance–voltage measurement for the erasing process in a TFT charge-trapping memory Open
Charge-trapping memories (CTMs) based on zinc tin oxide (ZTO) semiconductor thin-film transistors (TFTs) can be programmed by a positive gate voltage and erased by a negative gate voltage in conjunction with light illumination. To understa…
View article: Influences of top electrode reduction potential and operation ambient on the switching characteristics of tantalum oxide resistive switching memories
Influences of top electrode reduction potential and operation ambient on the switching characteristics of tantalum oxide resistive switching memories Open
Modulation of the oxygen distribution is liable for the electrical performance of oxide-based devices. When the top electrode (TE) is deposited on the active layer, an oxygen exchange layer (OEL) may be formed at the interface. Oxygen ions…
View article: Ambient Constancy of Passivation-Free Ultra-Thin Zinc Tin Oxide Thin Film Transistor
Ambient Constancy of Passivation-Free Ultra-Thin Zinc Tin Oxide Thin Film Transistor Open
An ultra-thin (5 nm-thick), unpassivated zinc tin oxide (ZTO) thin-film transistor TFT, fabricated with solution process, exhibits a good field-effect mobility (13 ∼ 14 cm2/Vs), small subthreshold swing (∼0.30 V/dec.) and high on/off curre…
View article: Thermal Performance of Cooling Enhancement of Miniature Flat Plate Heat Pipe Under Different Angle
Thermal Performance of Cooling Enhancement of Miniature Flat Plate Heat Pipe Under Different Angle Open
The possibility of cooling enhancement of flat plate heat pipes (FPHPs) by tilting was examined experimentally in this study. All of the FPHPs were made of Al and were partially filled with acetone. They had the same size of 120 mm (length…