Suguru Hasegawa
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View article: Underwater Pressure Lumen Expansion: A Novel Method to Overcome Lumen Collapse in Submucosal Endoscopy and Animal Endoscopic Full‐thickness Resection Models
Underwater Pressure Lumen Expansion: A Novel Method to Overcome Lumen Collapse in Submucosal Endoscopy and Animal Endoscopic Full‐thickness Resection Models Open
In endoscopic full‐thickness resection (EFTR), luminal collapse can occur due to communication between the gastrointestinal lumen and peritoneal cavity, making visualization and procedural continuity difficult. We propose the underwater pr…
View article: Site‐Specific Mutations on <scp><i>KRAS</i></scp>, <scp><i>NRAS</i></scp>, and <scp><i>BRAF</i></scp> Corelate With the Frequency of <scp>ctDNA</scp> in Colorectal Cancer
Site‐Specific Mutations on <span><i>KRAS</i></span>, <span><i>NRAS</i></span>, and <span><i>BRAF</i></span> Corelate With the Frequency of <span>ctDNA</span> in Colorectal Cancer Open
Background Early prediction of metastatic risk after tumor resection for colorectal cancer (CRC) is critical to improve treatment outcomes. Although circulating tumor DNA (ctDNA) is an important biomarker in CRC patients, positivity is var…
View article: Computer‐aided detection for esophageal achalasia (with video)
Computer‐aided detection for esophageal achalasia (with video) Open
Objectives Achalasia is an esophageal motility disorder that impairs quality of life and is often missed (20–50%) on endoscopy. A newly developed computer‐aided detection (CAD) software has shown high accuracy for achalasia diagnosis in pr…
View article: Euglycemic Diabetic Ketoacidosis With Sepsis and Acute Kidney Injury in Critically Ill Patients: A Case Series
Euglycemic Diabetic Ketoacidosis With Sepsis and Acute Kidney Injury in Critically Ill Patients: A Case Series Open
View article: Antireflux myoplasty: Endoscopic myoplasty with bilateral sling fiber plication for refractory gastroesophageal reflux disease
Antireflux myoplasty: Endoscopic myoplasty with bilateral sling fiber plication for refractory gastroesophageal reflux disease Open
Endoscopic antireflux therapy is a novel endoscopic treatment for refractory gastroesophageal reflux disease. We developed antireflux myoplasty (AR‐MP), a modified version of antireflux mucoplasty (ARM‐P), in which exposed bilateral sling …
View article: A Simple Procedure for Mesh Suture Fixation in Robotic Inguinal Hernia Repair: A Technical Report
A Simple Procedure for Mesh Suture Fixation in Robotic Inguinal Hernia Repair: A Technical Report Open
View article: A Rare Case of Streptococcal Toxic Shock Syndrome Associated With Pneumonia
A Rare Case of Streptococcal Toxic Shock Syndrome Associated With Pneumonia Open
View article: A Rare Case of Severe Pulmonary Embolism Complicated by the Rupture of a Pancreaticoduodenal Artery Aneurysm Due to Median Arcuate Ligament Syndrome and Left-sided Inferior Vena Cava
A Rare Case of Severe Pulmonary Embolism Complicated by the Rupture of a Pancreaticoduodenal Artery Aneurysm Due to Median Arcuate Ligament Syndrome and Left-sided Inferior Vena Cava Open
A 70-year-old man with a history of left-sided renal donation surgery 11 days earlier developed rupture of a pancreaticoduodenal artery (PDA) aneurysm caused by median arcuate ligament syndrome (MALS). The patient also had a congenital ano…
View article: Efficacy of peroral endoscopic myotomy for improving sleep problems in patients with achalasia
Efficacy of peroral endoscopic myotomy for improving sleep problems in patients with achalasia Open
Objectives Achalasia is an esophageal motility disorder of unknown etiology. However, no studies have determined the populations in which sleep problems occur and whether they are improved by peroral endoscopic myotomy (POEM). We investiga…
View article: Preventable diagnostic errors of lower gastrointestinal perforation: a secondary analysis of a large-scale multicenter retrospective study
Preventable diagnostic errors of lower gastrointestinal perforation: a secondary analysis of a large-scale multicenter retrospective study Open
View article: Preventable diagnostic errors of lower gastrointestinal perforation: a secondary analysis of a large-scale multicenter retrospective study
Preventable diagnostic errors of lower gastrointestinal perforation: a secondary analysis of a large-scale multicenter retrospective study Open
Background: Lower gastrointestinal perforation is an acute abdominal condition associated with a high mortality rate. Timely and accurate diagnosis is crucial. Nevertheless, a diagnostic delay has been estimated to occur in approximately o…
View article: Treatment outcomes and esophageal cancer incidence by disease type in achalasia patients undergoing peroral endoscopic myotomy: Retrospective study
Treatment outcomes and esophageal cancer incidence by disease type in achalasia patients undergoing peroral endoscopic myotomy: Retrospective study Open
Objectives This retrospective study aimed to compare treatment outcomes and postoperative courses, including the incidence of esophageal cancer (EC), according to disease types, in 450 achalasia patients who underwent peroral endoscopic my…
View article: Association Between Changes in Plasma Capecitabine Concentrations and Adverse Events in the Treatment of Colorectal Cancer
Association Between Changes in Plasma Capecitabine Concentrations and Adverse Events in the Treatment of Colorectal Cancer Open
View article: Successful Treatment of Complicated Pyogenic Spondylitis Due to Advanced Rectosigmoid Cancer Utilizing Vigorous Antibiotic Therapy and Minimally Invasive Robotic Colorectal Surgery: A Case Report
Successful Treatment of Complicated Pyogenic Spondylitis Due to Advanced Rectosigmoid Cancer Utilizing Vigorous Antibiotic Therapy and Minimally Invasive Robotic Colorectal Surgery: A Case Report Open
View article: Robotic-Assisted Total Gastrectomy for Gastric Cancer After Coronary Artery Bypass Grafting Using the Right Gastroepiploic Artery: A Case Report
Robotic-Assisted Total Gastrectomy for Gastric Cancer After Coronary Artery Bypass Grafting Using the Right Gastroepiploic Artery: A Case Report Open
View article: Practice guidelines on endoscopic surgery for qualified surgeons by the endoscopic surgical skill qualification system: Large intestine
Practice guidelines on endoscopic surgery for qualified surgeons by the endoscopic surgical skill qualification system: Large intestine Open
Laparoscopic surgery for colorectal diseases was first reported by Jacobs et al.1 and Fowler and White2 in 1991 and was introduced in Japan by Watanabe et al. in 1992 for early-stage colorectal cancer.3 This surgery has spread widely since…
View article: Impact of Preoperative Continued Aspirin Therapy on Perioperative Bleeding Complications in Patients Undergoing Gastrectomy for Malignancy
Impact of Preoperative Continued Aspirin Therapy on Perioperative Bleeding Complications in Patients Undergoing Gastrectomy for Malignancy Open
View article: Primary Neuroendocrine Carcinoma with Pagetoid Spread Arising from the Anal Canal: A Case Report
Primary Neuroendocrine Carcinoma with Pagetoid Spread Arising from the Anal Canal: A Case Report Open
症例は69歳の女性で,肛門痛を主訴に当院を受診した.肛門周囲に全周性の発赤とびらんを認め,下部消化管内視鏡検査で肛門管内に隆起性病変を認めた.肛門皮膚のびらんからの生検にて印環細胞癌と診断され,Paget現象を伴う原発性肛門管癌と考えた.造影CTにて右鼠径部にリンパ節の腫大を認め,経会陰内視鏡アプローチ併用腹腔鏡下直腸切断術,右鼠径リンパ節郭清を施行した.病理組織学検査では肛門皮下に異型上皮細胞の充実胞巣と一部に中分化型腺癌を認め,表皮内に印環細胞様形態の癌細胞が進展してい…
View article: Feasibility of robotic-assisted surgery in advanced rectal cancer: a multicentre prospective phase II study (VITRUVIANO trial)
Feasibility of robotic-assisted surgery in advanced rectal cancer: a multicentre prospective phase II study (VITRUVIANO trial) Open
Background The potential benefits of robotic-assisted compared with laparoscopic surgery for locally advanced cancer have not been sufficiently proven by prospective studies. One factor is speculated to be the lack of strict surgeon criter…
View article: Laparoscopic sigmoid colectomy for transverse colonic varices due to an inferior mesenteric arteriovenous fistula
Laparoscopic sigmoid colectomy for transverse colonic varices due to an inferior mesenteric arteriovenous fistula Open
View article: Enzymatic Fat Dissolution Improves Detection of Small Lymph Nodes in Colon Cancer Surgery
Enzymatic Fat Dissolution Improves Detection of Small Lymph Nodes in Colon Cancer Surgery Open
View article: A pilot study on the safety and efficacy of neoadjuvant chemo‑adoptive immunotherapy for locally advanced rectal cancer
A pilot study on the safety and efficacy of neoadjuvant chemo‑adoptive immunotherapy for locally advanced rectal cancer Open
The safety and efficacy of combination therapy of immune cell therapy and chemotherapy [chemo-adoptive immunotherapy (CAIT)] for patients with stage IV or recurrent colorectal cancer have been reported. In the present study, the safety and…
View article: Local Recurrence of Rectal Cancer After Transanal Total Mesorectal Excision and Risk Factors: A Nationwide Multicenter Cohort Study in Japan
Local Recurrence of Rectal Cancer After Transanal Total Mesorectal Excision and Risk Factors: A Nationwide Multicenter Cohort Study in Japan Open
Objective: To investigate the oncological outcomes after transanal total mesorectal excision (TaTME) for rectal cancer and risk factors for local recurrence (LR). Background: A high LR rate with a multifocal pattern early after TaTME has b…
View article: Effect of heating insufflation tube of AirSeal system on laparoscopic surgery
Effect of heating insufflation tube of AirSeal system on laparoscopic surgery Open
The AirSeal system (CONMED, NY, USA) can outstandingly keep pneumoperitoneum stable. However, water droplets form on the access port, impairing the performance of comfortable surgical procedures because of the resultant wet surgical field.…
View article: A Case of Idiopathic Appendiceal Intussusception Difficult to Distinguish from an Appendiceal Tumor
A Case of Idiopathic Appendiceal Intussusception Difficult to Distinguish from an Appendiceal Tumor Open
View article: Safety and Feasibility of Gastrectomy in Super Elderly Patients (Aged ≥ 80): A Propensity Score-Matched Analysis
Safety and Feasibility of Gastrectomy in Super Elderly Patients (Aged ≥ 80): A Propensity Score-Matched Analysis Open
Gastrectomy for elderly patients with GC can be considered safe based on short-term outcomes. In terms of long-term results, elderly patients are not inferior to non-elderly patients if the patients' backgrounds are the same. On the other …
View article: The frequency of ctDNA with KRAS, NRAS, and BRAF mutations in colorectal cancer is associated with the mutation site
The frequency of ctDNA with KRAS, NRAS, and BRAF mutations in colorectal cancer is associated with the mutation site Open
Early prediction of metastatic risk after tumor resection for colorectal cancer (CRC) is critical to improve treatment outcomes. Although circulating tumor DNA (ctDNA) is an important biomarker in CRC patients, methods and cutoff values ha…
View article: Endoscopic ligation technique for refractory gastrotracheal fistula
Endoscopic ligation technique for refractory gastrotracheal fistula Open
Endoscopic therapy has recently undergone remarkable progress, including the use of suturing procedures within the gastrointestinal tract using flexible endoscopes. However, existing suturing techniques primarily involve closure using inst…
View article: Enzymatic fat dissolution improves detection of small lymph nodes in colon cancer surgery
Enzymatic fat dissolution improves detection of small lymph nodes in colon cancer surgery Open
Background Accurate lymph node evaluation is essential for staging colon cancer and guiding postoperative treatment decisions. In this study, we compared the efficacy of a simple enzymatic fat dissolution method with that of the convention…
View article: Trans-anal Minimally Invasive Surgery Combined With a Robotic Anterior Approach for Sleeve Resection of a Huge Rectal Gastrointestinal Stromal Tumor
Trans-anal Minimally Invasive Surgery Combined With a Robotic Anterior Approach for Sleeve Resection of a Huge Rectal Gastrointestinal Stromal Tumor Open
Due to anatomical complexity, large rectal gastrointestinal stromal tumors (GISTs) in the pelvis at the anterior aspect often require extended abdominal surgery to obtain clear surgical margins. Here, we show our trans-anal minimally invas…