Magdy A. Amin
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View article: Comparison of Clinical Outcome in Surgically Treated Vs Conservatively Manged Rockwood Type III ACJ Dislocation
Comparison of Clinical Outcome in Surgically Treated Vs Conservatively Manged Rockwood Type III ACJ Dislocation Open
Background: Acromioclavicular joint (ACJ) dislocations are frequently encountered shoulder injuries, particularly in active individuals. The management of Rockwood Type III injuries remains contentious, with both surgical and conservative …
View article: Statistical Study of Confined Filament/Prominence Eruptions during Solar Cycle 23
Statistical Study of Confined Filament/Prominence Eruptions during Solar Cycle 23 Open
Filament/prominence eruptions can have a significant impact on Earth's upper atmosphere and space environment, and are the primary drivers of what is now called space weather. To distinguish the different types of filament eruptions we sta…
View article: Draft genome sequence of a prodigiosin-hyperproducing <i>Serratia marcescens</i> strain isolated from Cairo, Egypt
Draft genome sequence of a prodigiosin-hyperproducing <i>Serratia marcescens</i> strain isolated from Cairo, Egypt Open
Serratia marcescens is a Gram-negative bacterium with both environmental and host-associated strains. Pigmentation is reportedly inversely correlated with infection frequency, and prodigiosin is one of Serratia pigments that has medical an…
View article: In-Vitro Inactivation of Sabin-Polioviruses for Development of Safe and Effective Polio Vaccine
In-Vitro Inactivation of Sabin-Polioviruses for Development of Safe and Effective Polio Vaccine Open
After years of global collaboration; we are steps away from a polio-free world. However, the currently conventional inactivated polio vaccine (cIPV) is suboptimal for the post eradication era. cIPV production cost and biosafety hazards hin…
View article: Complete genome sequence and comparative analysis of two potential probiotics Bacillus subtilis isolated from honey and honeybee microbiomes
Complete genome sequence and comparative analysis of two potential probiotics Bacillus subtilis isolated from honey and honeybee microbiomes Open
We introduce complete genome sequence of two new B. subtilis strains HMNig-2 and MENO2 with probiotic potential and as cell factories for the production of levan and other valuable components for pharmaceutical and industrial applications.
View article: Interferon Gamma Release Assay, A Powerful Tool for the Detection of Human and Bovine Tuberculosis in the Greater Cairo Area Compared to Other Diagnostic Tools
Interferon Gamma Release Assay, A Powerful Tool for the Detection of Human and Bovine Tuberculosis in the Greater Cairo Area Compared to Other Diagnostic Tools Open
Rapid detection is essential for the elimination and control of tuberculosis (TB) worldwide. Our study aimed to
\nshow the current and actual patterns of human and bovine TB distribution in the Greater Cairo Area community by the
\napplica…
View article: Acquisition of Colistin Resistance Links Cell Membrane Thickness Alteration with a Point Mutation in the lpxD Gene in Acinetobacter baumannii
Acquisition of Colistin Resistance Links Cell Membrane Thickness Alteration with a Point Mutation in the lpxD Gene in Acinetobacter baumannii Open
Acinetobacter baumannii is one of the most common causes of nosocomial infections in intensive care units. Its ability to acquire diverse mechanisms of resistance limits the therapeutic choices for its treatment. This especially concerns c…
View article: Basil Essential Oil and Its Nanoemulsion Mitigate Non Alcoholic Steatohepatitis in Rat Model with Special Reference to Gut Microbiota
Basil Essential Oil and Its Nanoemulsion Mitigate Non Alcoholic Steatohepatitis in Rat Model with Special Reference to Gut Microbiota Open
The present research evaluated the protective effect of basil essential oil nanoemulsion (BNO) and its parent basil essential oil (BO) towards steatohepatitis. Chemical composition of BO was assessed followed by formulation into different …
View article: Interleukin-28B (IL-28B) and Interferon –Gamma (INF-γ) Levels in Patients with Chronic Hepatitis C Viral (HCV) Infection
Interleukin-28B (IL-28B) and Interferon –Gamma (INF-γ) Levels in Patients with Chronic Hepatitis C Viral (HCV) Infection Open
Objectives: We aimed to studythe effect of Schsitosoma mansoni co-infection with hepatitis C virus (HCV) on IL-28B levels. Design: We collected plasma from107outpatients(range30–81 years old) from six governates of Delta, Egypt attending K…
View article: Comparative Structural Analysis of Different Mycobacteriophage-Derived Mycolylarabinogalactan Esterases (Lysin B)
Comparative Structural Analysis of Different Mycobacteriophage-Derived Mycolylarabinogalactan Esterases (Lysin B) Open
Mycobacteriophage endolysins have emerged as a potential alternative to the current antimycobacterial agents. This study focuses on mycolylarabinogalactan hydrolase (LysB) enzymes of the α/β-hydrolase family, which disrupt the unique mycol…
View article: Emergence of colistin resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli strains isolated from cancer patients
Emergence of colistin resistance in multidrug-resistant Klebsiella pneumoniae and Escherichia coli strains isolated from cancer patients Open
Background Colistin resistance is mainly driven by alterations in the Gram-negative outer membrane lipopolysaccharides and is caused, in most cases, by mutations in mgrB gene. However, the recent emergence of plasmid-encoded colistin resis…
View article: Combination Therapy of Mesenchymal Stromal Cells and Interleukin-4 Attenuates Rheumatoid Arthritis in a Collagen-Induced Murine Model
Combination Therapy of Mesenchymal Stromal Cells and Interleukin-4 Attenuates Rheumatoid Arthritis in a Collagen-Induced Murine Model Open
Rheumatoid arthritis (RA) is a disease of the joints that causes decreased quality of life. Mesenchymal stromal cells (MSCs) have immunosuppressive properties, with possible use in the treatment of RA. Similarly, interleukin (IL)-4 has bee…
View article: Characterization of The Type of Response to Different HCV Antigens and Quantification of Viral Load in Newly Diagnosed Hepatocellular Carcinoma Patients
Characterization of The Type of Response to Different HCV Antigens and Quantification of Viral Load in Newly Diagnosed Hepatocellular Carcinoma Patients Open
Background: Hepatitis C virus (HCV) is a blood born virus that is considered a major cause of chronic liver disease and hepatocellular carcinoma (HCC) worldwide.HCV is thought to induce HCC either indirectly or directly by the effect of it…
View article: Preclinical study of safety and immunogenicity of combined rubella and human papillomavirus vaccines: Towards enhancing vaccination uptake rates in developing countries
Preclinical study of safety and immunogenicity of combined rubella and human papillomavirus vaccines: Towards enhancing vaccination uptake rates in developing countries Open
Rubella vaccine was not part of national immunization programs (NIP) in several countries in the Middle East and North Africa (MENA), South-East Asia (SEA), and South Africa regions until the year 2000. Therefore, immunization coverage of …
View article: Novel blaCTX-M variants and genotype-phenotype correlations among clinical isolates of extended spectrum beta lactamase-producing Escherichia coli
Novel blaCTX-M variants and genotype-phenotype correlations among clinical isolates of extended spectrum beta lactamase-producing Escherichia coli Open
The rapid emergence of multiresistant microbial pathogens, dubbed superbugs, is a serious threat to human health. Extended spectrum beta lactamase (ESBL)-producing Escherichia coli is a superbug causing worldwide outbreaks, necessitating t…
View article: Photometric analysis of newly discovered open clusters SAI 24 and SAI 94 based on PPMXL catalogue
Photometric analysis of newly discovered open clusters SAI 24 and SAI 94 based on PPMXL catalogue Open
In our present work, we studied the photometric characteristics (core radius, limiting radius, reddening... etc.) as well as their dynamical state of the two newly discovered open clusters, SAI 24 and SAI 94. We investigated their photomet…
View article: Molecular Characterization of Aniline Biodegradation by Some Bacterial Isolates having Unexpressed Catechol 2,3-Dioxygenase Gene
Molecular Characterization of Aniline Biodegradation by Some Bacterial Isolates having Unexpressed Catechol 2,3-Dioxygenase Gene Open
Aromatic amines are potential mutagens and carcinogens, so biodegradation of them may protect our environment by safely getting rid of these compounds. In the present study, 5 aniline degrading isolates were recovered from 30 samples of se…
View article: Dissemination of ST101 blaOXA-48 producing Klebsiella pneumoniae at tertiary care setting
Dissemination of ST101 blaOXA-48 producing Klebsiella pneumoniae at tertiary care setting Open
Introduction: The worldwide dissemination of the acquired carbapenemases in Gram-negative bacteria is a strongly expressed demand for the emergence of post antibiotic era. The aim of this study was to test the production of carbapenemase b…
View article: Isolation, Characterization and Bioactivities of an Extracellular Polysaccharide Produced from Streptomyces sp. MOE6
Isolation, Characterization and Bioactivities of an Extracellular Polysaccharide Produced from Streptomyces sp. MOE6 Open
A Streptomyces strain was isolated from soil and the sequence of 1471 nucleotides of its 16S rDNA showed 99% identity to Streptomyces sp. HV10. This newly isolated Streptomyces strain produced an extracellular polysaccharide (EPS) composed…
View article: SCHSITOSOMA MANSONI CO-INFECTION WITH HEPATITIS C VIRUS IS ASSOCIATED WITH INCREASED INTERLEUKIN-28B PLASMA LEVELS IN EGYPTIAN POPULATION
SCHSITOSOMA MANSONI CO-INFECTION WITH HEPATITIS C VIRUS IS ASSOCIATED WITH INCREASED INTERLEUKIN-28B PLASMA LEVELS IN EGYPTIAN POPULATION Open
Intestinal schistosomiasis and hepatitis C viral (HCV) infections are endemic in Egypt with coinfections leading to increased severity of liver diseases.Previous studies characterized the immune responses to treatment in co-infection.Howev…
View article: Complete Genome Sequencing of <i>Streptomyces</i> sp. Strain MOE7, Which Produces an Extracellular Polysaccharide with Antioxidant and Antitumor Activities
Complete Genome Sequencing of <i>Streptomyces</i> sp. Strain MOE7, Which Produces an Extracellular Polysaccharide with Antioxidant and Antitumor Activities Open
Streptomyces sp. strain MOE7 is a Gram-positive filamentous bacterium isolated from agricultural soil in Columbia, Missouri, USA. Strain MOE7 produces an extracellular polysaccharide with antioxidant and antitumor activities. Through PacBi…
View article: Optimization of prodigiosin production by Serratia marcescens using crude glycerol and enhancing production using gamma radiation
Optimization of prodigiosin production by Serratia marcescens using crude glycerol and enhancing production using gamma radiation Open
Prodigiosin is a red pigment produced by Serratia marcescens. Prodigiosin is regarded as a promising drug owing to its reported characteristics of possessing anti-microbial, anti-cancer, and immunosuppressive activity. A factorial design w…
View article: Synergistic Effect of Coadministration of <em>Haemophilus influenzae</em> and <em>Neisseria meningitidis</em> Vaccines on Immune Responses to Meningitis in Mouse Model
Synergistic Effect of Coadministration of <em>Haemophilus influenzae</em> and <em>Neisseria meningitidis</em> Vaccines on Immune Responses to Meningitis in Mouse Model Open
Meningitis is a severe disease associated with death in children under five with highest rates of infections under age of one. Vaccines for Neisseria meningitides and Haemophilus influenza are used to prevent the main causative agents of m…
View article: Development and evaluation of a novel vaccine against prevalent invasive multi-drug resistant strains of<i>Streptococcus pneumoniae</i>
Development and evaluation of a novel vaccine against prevalent invasive multi-drug resistant strains of<i>Streptococcus pneumoniae</i> Open
Streptococcus pneumoniae is a pathogen that causes serious invasive infections, such as septicemia, meningitis and pneumonia in addition to mild upper respiratory tract infections. Protection from pneumococcal diseases is thought to be med…
View article: Cancer derived peptide of vacuolar ATPase ‘a2’ isoform promotes neutrophil migration by autocrine secretion of IL-8
Cancer derived peptide of vacuolar ATPase ‘a2’ isoform promotes neutrophil migration by autocrine secretion of IL-8 Open
Neutrophils play significant regulatory roles within the tumor microenvironment by directly promoting tumor progression that leads to poor clinical outcomes. Identifying the tumor associated molecules that regulate neutrophil infiltration …
View article: Isolation and characterization of two malathiondegrading Pseudomonas sp. in Egypt
Isolation and characterization of two malathiondegrading Pseudomonas sp. in Egypt Open
Pseudomonas aeruginosa and Pseudomonas mendocina degrading malathion were studied. Morphological, biochemical and 16S rRNA genes for bacterial identification were selected. Biodegradation of some organophosphorus compounds with the 2 ba…
View article: Single step biotransformation of corn oil phytosterols to boldenone by a newly isolated Pseudomonas aeruginosa
Single step biotransformation of corn oil phytosterols to boldenone by a newly isolated Pseudomonas aeruginosa Open
A new potent Pseudomonas aeruginosa isolate capable for biotransformation of corn oil phytosterol (PS) to 4-androstene-3, 17-dione (AD), testosterone (T) and boldenone (BOL) was identified by phenotypic analysis and 16S rRNA gene sequencin…