Sujata Chaturvedi
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View article: The Ellipsoid Zone Is a Structural Biomarker for Visual Outcomes in Diabetic Macular Edema and Macular Hole Management
The Ellipsoid Zone Is a Structural Biomarker for Visual Outcomes in Diabetic Macular Edema and Macular Hole Management Open
Objectives: The goal was to study the ellipsoid zone (EZ) as a structural biomarker for final visual outcomes after pharmacological intervention in center-involving diabetic macular edema (DME) and surgical intervention for full-thickness …
View article: Serum pro-brain natriuretic peptide correlates with optical coherence tomography indices in diabetic retinopathy.
Serum pro-brain natriuretic peptide correlates with optical coherence tomography indices in diabetic retinopathy. Open
The serum pro-BNP levels were higher in the NPDR group than in the NoDR group and much lower in the PDR group than in the NPDR group, reflecting a lowering of the protective barrier. These results correlated with the changes in various OCT…
View article: Toxoplasma Retinitis: A Picture-Perfect Presentation
Toxoplasma Retinitis: A Picture-Perfect Presentation Open
Toxoplasma Retinitis: A picture-perfect presentation where SD-OCT serves as a crucial supplemental imaging tool for both diagnosing and monitoring patients with ocular toxoplasmosis.
View article: True Aneurysm of Superficial Temporal Artery Presenting as Subcutaneous Scalp Swelling: A Diagnostic Conundrum in Two Cases
True Aneurysm of Superficial Temporal Artery Presenting as Subcutaneous Scalp Swelling: A Diagnostic Conundrum in Two Cases Open
True aneurysms of the superficial temporal artery (STA) are very rarely encountered in clinical practice. Unlike pseudoaneurysms neither they have any preceding history of trauma nor are they associated with atherosclerosis or any other co…
View article: Intraaxial epidermoid cyst: Report of a rare case and review of literature
Intraaxial epidermoid cyst: Report of a rare case and review of literature Open
Intra-axial epidermoid cysts are rare intracranial space occupying lesions, accounting for ∼1% of all intracranial tumours and are commonly located in the cisternal spaces, mainly in the cerebellopontine angle and parasellar cisterns. A pu…
View article: Multiple Primary Bilateral Cerebral Echinococcosis in an Adult: A Neurological Rarity
Multiple Primary Bilateral Cerebral Echinococcosis in an Adult: A Neurological Rarity Open
Although cases of intracranial hydatid cysts are commonly encountered, majority of them are secondary and are seen in children. Primary bilateral multiple intracranial hydatid cysts in adults are a neurological rarity. Intracranial involve…
View article: Histopathological Spectrum of Adult and Paediatric Meningiomas
Histopathological Spectrum of Adult and Paediatric Meningiomas Open
Introduction: Meningiomas are a group of neoplasms showing a spectrum of histopathological variants, mostly corresponding to World Health Organization (WHO) grade I. However, certain histologic variants correspond histologically to WHO gra…
View article: Primary Dural Non-Hodgkin’s Lymphoma as a Diagnostic Pitfall: Report of a Rare Presentation with Review of Literature
Primary Dural Non-Hodgkin’s Lymphoma as a Diagnostic Pitfall: Report of a Rare Presentation with Review of Literature Open
Primary central nervous system lymphomas (PCNSLs) account for 2%–3% of all primary brain tumors. Lymphomas arising from the dura, without brain and other systemic involvement, constitute a tiny fraction of this rare group. Most dural lymph…
View article: Extra-axial adult cerebellopontine angle medulloblastoma: Revisiting a rare entity
Extra-axial adult cerebellopontine angle medulloblastoma: Revisiting a rare entity Open
A purely extra-axial position of medulloblastoma in adults at cerebellopontine (CP) angle is extremely rare. To the best of our knowledge, only ten cases have been reported till date. The authors report a case of extra-axial medulloblastom…
View article: Auditing Histopathology Processes to Augment Reporting Quality: An Objective Analysis in a Tertiary Care Neuropathology Laboratory
Auditing Histopathology Processes to Augment Reporting Quality: An Objective Analysis in a Tertiary Care Neuropathology Laboratory Open
Background: Laboratory audits are an integral component of the continuous quality improvement process and one of the key elements of quality control in the laboratories. These audits are primarily concerned with the everyday aspects of lab…
View article: Gene expression based profiling of pleomorphic xanthoastrocytoma highlights two prognostic subgroups.
Gene expression based profiling of pleomorphic xanthoastrocytoma highlights two prognostic subgroups. Open
This is the first comprehensive study highlighting distinct molecular subgroups of PXA. The differentially expressed genes between two clusters may potentially be used for developing histology independent classification schemes, prognostic…
View article: Histopathological Mapping of Meningiomas: A 10-year Retrospective Analysis
Histopathological Mapping of Meningiomas: A 10-year Retrospective Analysis Open
Background Meningiomas are a group of neoplasms showing a spectrum of histopathological variants, mostly corresponding to World Health Organization (WHO) grade I. However, certain histologic variants correspond histologically to WHO grades…
View article: Analysis of Histomorphological/molecular Association and Immune Checkpoint Regulators in Epithelioid Glioblastoma and Pleomorphic Xanthoastrocytoma: Are These Tumors Potential Candidate for Immune Checkpoint Blockade
Analysis of Histomorphological/molecular Association and Immune Checkpoint Regulators in Epithelioid Glioblastoma and Pleomorphic Xanthoastrocytoma: Are These Tumors Potential Candidate for Immune Checkpoint Blockade Open
IntroductionEpithelioid glioblastoma (eGB) was adopted as a provisional entity in the 2016 WHO classification of central nervous tumors. Accurate diagnosis of eGBs and pleomorphic xanthoastrocytoma (PXA) is sometimes challenging owing to o…
View article: Gangliocytic paraganglioma of the spine
Gangliocytic paraganglioma of the spine Open
"Paragangliomas are rare, encapsulated, benign neuroendocrine tumors that can arise from the adrenal medulla or extra-adrenal paraganglia. Extra-adrenal paragangliomas may develop a gangliocytic component with ganglion cells (Gangliocytic …
View article: Historadiological Correlation of Cerebellopontine Angle Tumors: Series of 122 Cases
Historadiological Correlation of Cerebellopontine Angle Tumors: Series of 122 Cases Open
View article: Commentary
Commentary Open
The 2016 “WHO Classification of Tumours of the Central Nervous System” has defined nine molecular groups of ependymoma and their key characteristics. This is likely to have a great bearing on stratification of patients for adjuvant therapy…
View article: Revisiting metastatic central nervous system tumors with unknown primary using clinicopathological findings: A single neurosciences institutional study
Revisiting metastatic central nervous system tumors with unknown primary using clinicopathological findings: A single neurosciences institutional study Open
Detection of the primary site in metastatic CNS tumors is possible by adopting this simple and effective diagnostic approach at centers/hospitals having cost and other constraints.
View article: Diffuse midline glioma, H3-K27M mutant: Awareness leads to identification
Diffuse midline glioma, H3-K27M mutant: Awareness leads to identification Open
Midline astrocytic neoplasms have distinct molecular characteristics, quite different from astrocytic neoplasms with similar morphology but not located in the midline. It is imperative that neuropathologists should be aware of the existenc…
View article: Intramedullary schwannoma of conus medullaris: rare site for a common tumor with review of literature
Intramedullary schwannoma of conus medullaris: rare site for a common tumor with review of literature Open
View article: Congenital skull anomaly with multiple brain stones and symptomatic meningioma of medial sphenoid wing
Congenital skull anomaly with multiple brain stones and symptomatic meningioma of medial sphenoid wing Open
Intracranial calcifications are not uncommon and are mostly seen with intracerebral hematomas, tuberculomas, and brain tumors. These lesions may be intra- or extra-axial and occasionally pose challenge in the diagnosis. We report a case of…
View article: Assessment of microvascular patterns and density in glioblastoma and their correlation with matrix metalloproteinase-9, p53, glial fibrillary acidic protein, and Ki-67
Assessment of microvascular patterns and density in glioblastoma and their correlation with matrix metalloproteinase-9, p53, glial fibrillary acidic protein, and Ki-67 Open
Background and Aim: Microvascular patterns (MVPs) and microvessel density (MVD) can influence the progression of glioblastomas. This study aims to study MVP and MVD using immunohistochemistry, and examine any correlation with the expressio…
View article: Peripheral neuropathy and the role of nerve biopsy: A revisit
Peripheral neuropathy and the role of nerve biopsy: A revisit Open
With advanced nerve conduction studies available, nerve biopsy is losing its relevance. However, in our experience, nerve biopsy did complement the clinical findings and nerve conduction studies, with which a close correlation is required …
View article: Analysis of molecular markers in glioblastoma and correlation with survival pattern
Analysis of molecular markers in glioblastoma and correlation with survival pattern Open
Objective: The objective of this study was to apply the newly recommended mandatory immunohistochemical (IHC) markers, isocitrate dehydrogenase (IDH) and ATRX, in addition to our previously applied panel of p53, epidermal growth factor rec…
View article: Duchenne muscular dystrophy: A immunohistochemical profile and deletion pattern in dystrophin gene in North Indian population
Duchenne muscular dystrophy: A immunohistochemical profile and deletion pattern in dystrophin gene in North Indian population Open
Background: Duchenne muscular dystrophy (DMD), one of the most common X linked muscular disorder, affecting 1 in 3500 male births and is caused by mutation in dystrophin gene. 65% of DMD cases are caused by large deletion of dystrophin gen…
View article: Spinal tumour: primary cervical extradural meningioma at an unusual location
Spinal tumour: primary cervical extradural meningioma at an unusual location Open
Extradural spinal meningiomas are extremely rare, more so in the cervical region. A purely extradural location as reported in this paper is quite exceptional. The authors report a case of extradural meningioma in a 50-year-old male located…
View article: Intravascular papillary endothelial hyperplasia presenting as a cystic mass in the scalp with underlying bone involvement: A rare entity
Intravascular papillary endothelial hyperplasia presenting as a cystic mass in the scalp with underlying bone involvement: A rare entity Open
Intravascular papillary endothelial hyperplasia (IPEH) also known as Masson's hemangioma is a rare benign reactive vascular lesion of the skin and subcutaneous tissue. It is usually confined to the lumen of preexisting vessels/vascular mal…
View article: Hyper acute demyelinating encephalomyelitis of childhood: A rare entity
Hyper acute demyelinating encephalomyelitis of childhood: A rare entity Open
A young child with catastrophic neurological illness diagnosed as a rare variant of acute demyelinating encephalomyelitis (ADEM). She succumbed to her illness despite of aggressive and appropriate management. Malignant demyelinating enceph…
View article: Giant cell glioblastoma in a child with clinical and family history of neurofibromatosis
Giant cell glioblastoma in a child with clinical and family history of neurofibromatosis Open
We report a case of giant cell glioblastoma (GCG) in a 13-year-old child with clinical features and family history of neurofibromatosis type 1 (NF1). To the best of our knowledge, only two cases of GCG have been reported in a scenario of N…
View article: Enigmatic Weak D antigen: An Experience in a Tertiary Care Hospital of East Delhi
Enigmatic Weak D antigen: An Experience in a Tertiary Care Hospital of East Delhi Open
Considerably high frequency of weak D antigen was noticed in study samples of this hospital. With this data based information, it is felt worthwhile to perform weak D testing routinely of those individuals who are negative with saline anti…
View article: Extra-axial medulloblastoma in the cerebellopontine angle: Report of a rare entity with review of literature
Extra-axial medulloblastoma in the cerebellopontine angle: Report of a rare entity with review of literature Open
With only 33 cases reported so far, a purely extra-axial position of medulloblastoma at cerebellopontine (CP) angle is quite exceptional. We report a case of extra-axial medulloblastoma in a 15-year-old male child located in the CP angle t…