Sujatha Sistla
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View article: Trichomycosis Axillaris: A Clinicoetiological Study
Trichomycosis Axillaris: A Clinicoetiological Study Open
Background: Trichomycosis axillaris (TA) is the most common superficial bacterial infection of hair shaft, mainly of axillary hairs and producing pigmented concretions around hair shaft caused by various species of corynebacteria. Aims and…
View article: Arrhythmia Recurrence and Rhythm Control Strategies After Catheter Ablation of Newly Diagnosed Atrial Fibrillation (ARRC-AF Study)
Arrhythmia Recurrence and Rhythm Control Strategies After Catheter Ablation of Newly Diagnosed Atrial Fibrillation (ARRC-AF Study) Open
In this study, additional rhythm-control strategies were frequently continued after index ablation. One in 6 patients underwent repeat ablation, with the majority receiving concomitant AAD therapy. These data indicate that a combined strat…
View article: In vitro efficacy of levonadifloxacin against methicillin-resistant Staphylococcus aureus (MRSA) including hVISA isolates collected across India
In vitro efficacy of levonadifloxacin against methicillin-resistant Staphylococcus aureus (MRSA) including hVISA isolates collected across India Open
The present study demonstrated 100 % susceptibility to levonadifloxacin among the tested isolates of MRSA, highlighting its promising clinical potential for treating infections caused by this organism. Furthermore, the study recorded a con…
View article: An insight into Eikenella corrodens infections in humans-experience from a tertiary care centre in South India
An insight into Eikenella corrodens infections in humans-experience from a tertiary care centre in South India Open
Eikenella corrodens is present in the natural microbial community of mucosal surfaces, but it can potentially cause illness in diverse medical contexts. We retrospectively analysed medical records of twelve cases of E. corrodens infection …
View article: Outbreak of Burkholderia cenocepacia in an intensive care unit of a tertiary care hospital identified by pulsed-field gel electrophoresis
Outbreak of Burkholderia cenocepacia in an intensive care unit of a tertiary care hospital identified by pulsed-field gel electrophoresis Open
Nosocomial outbreaks of Burkholderia cepacia complex, transmitted through contaminated medical surfaces or equipment have been reported. Pulsed-field Gel Electrophoresis (PFGE) is recognized as the "gold standard" for molecular subtyping, …
View article: Species distribution and antimicrobial susceptibility of Burkholderia cepacia complex isolates in clinical infections: Experience from a tertiary care hospital, Southern India
Species distribution and antimicrobial susceptibility of Burkholderia cepacia complex isolates in clinical infections: Experience from a tertiary care hospital, Southern India Open
This study provides valuable insights into the prevalence, clinical associations, and antibiotic susceptibility of Bcc in India. It highlights the importance of Bcc as a nosocomial pathogen, especially in vulnerable patient populations. Th…
View article: Utility of quantitative loop mediated isothermal amplification (qLAMP) assay for the diagnosis of invasive pneumococcal disease (IPD)
Utility of quantitative loop mediated isothermal amplification (qLAMP) assay for the diagnosis of invasive pneumococcal disease (IPD) Open
The performance of qLAMP assay can vary based on the specimen type. It has very high specificity and had substantial to almost perfect agreement, and thus may be an alternative to qPCR for the diagnosis of IPD.
View article: Comparative pangenome analysis of major pneumococcal genotypes from India
Comparative pangenome analysis of major pneumococcal genotypes from India Open
Background Pneumococcal genomes are highly dynamic with varying core genome sizes. The genotype classification system, Global Pneumococcal Sequence Clusters, identified patterns within genotype and antibiotic resistance. Few genotypes like…
View article: GPSC pangenome analysis
GPSC pangenome analysis Open
The data represents core genomes of major GPSC types and Indian Pneumococcal Pangenome (file name: coreGenome.*). All the raw data is presented in the supplementary file.
View article: Influence of COVID-19 over seasonal influenza activity in southern India
Influence of COVID-19 over seasonal influenza activity in southern India Open
Basic epidemiological data is urgently needed in order to ascertain the changes brought about by COVID-19 pandemic, and help researchers, clinicians, and policy makers in addressing these issues. Data on influenza positivity from 2009 to 2…
View article: Evaluation of different linezolid susceptibility testing methods and detection of linezolid resistance gene (cfr) in staphylococcal isolates
Evaluation of different linezolid susceptibility testing methods and detection of linezolid resistance gene (cfr) in staphylococcal isolates Open
Linezolid is an effective oxazolidinone antibiotic against multi resistant Gram-positive organisms. Linezolid resistance is an emerging problem and some controversy exists about the reliability of different phenotypic methods of linezolid …
View article: Genome sequences of <i>bla</i> <sub>NDM-1</sub> producing <i>Acinetobacter lactucae</i> isolated from immunocompromised patients in India
Genome sequences of <i>bla</i> <sub>NDM-1</sub> producing <i>Acinetobacter lactucae</i> isolated from immunocompromised patients in India Open
Among the species within Acb- complex, Acinetobacter lactucae has not been frequently isolated from clinical settings, unlike Acinetobacter baumannii , which is an important nosocomial pathogen. We report the genomic sequences of A. lactuc…
View article: Structure Elucidation and Interaction Dynamics of MefA-MsrD Efflux Proteins in <i>Streptococcus pneumoniae</i>: Impact on Macrolide Susceptibility
Structure Elucidation and Interaction Dynamics of MefA-MsrD Efflux Proteins in <i>Streptococcus pneumoniae</i>: Impact on Macrolide Susceptibility Open
Macrolides are empirically used to treat bacterial community-acquired pneumonia (CAP). Streptococcus pneumoniae, being the major pathogen responsible for bacterial CAP with high mortality rates, express MefA-MsrD efflux pumps to hin…
View article: A rare and fatal case of tubo-ovarian abscess due to Burkholderia pseudomallei presenting as puerperal sepsis
A rare and fatal case of tubo-ovarian abscess due to Burkholderia pseudomallei presenting as puerperal sepsis Open
Introduction. Melioidosis is an emerging life-threatening infectious disease caused by the Gram-negative Burkholderia pseudomallei found in contaminated soil and surface ground water. It often presents with varied clinical manifestations a…
View article: <xhtml:span xmlns:xhtml="http://www.w3.org/1999/xhtml" xml:lang="en">A rare and fatal case of tubo-ovarian abscess due to&#160;<em>Burkholderia pseudomallei</em>&#160;presenting as puerperal sepsis</xhtml:span>
A rare and fatal case of tubo-ovarian abscess due to <em>Burkholderia pseudomallei</em> presenting as puerperal sepsis Open
Introduction : Melioidosis is an emerging life threatening infectious disease caused by Gram negative bacilli Burkholderia pseudomallei found in contaminated soil and surface ground water . It often presents with varied clinical manifestat…
View article: Early- vs Late-onset Ventilator-associated Pneumonia in Critically Ill Adults: Comparison of Risk Factors, Outcome, and Microbial Profile
Early- vs Late-onset Ventilator-associated Pneumonia in Critically Ill Adults: Comparison of Risk Factors, Outcome, and Microbial Profile Open
Gunalan A, Sastry AS, Ramanathan V, Sistla S. Early- vs Late-onset Ventilator-associated Pneumonia in Critically Ill Adults: Comparison of Risk Factors, Outcome, and Microbial Profile. Indian J Crit Care Med 2023;27(6):411-415.
View article: Anaerobic Profile of Intra-abdominal Infections – A 23-Year Retrospective Study
Anaerobic Profile of Intra-abdominal Infections – A 23-Year Retrospective Study Open
Obligate anaerobes, which are part of normal intestinal flora are now gaining pathogenic potential by becoming more virulent and causing moderate to severe abdominal infections. Moreover, there is delay in initiation of appropriate antimic…
View article: Clinical Profile and Predictors of Mortality among Patients with Melioidosis
Clinical Profile and Predictors of Mortality among Patients with Melioidosis Open
Introduction: Melioidosis is an under-recognized but important infection with high mortality and morbidity. It is endemic along the coastal regions of the Southern part of India. The present study focuses on the varied clinical manifestati…
View article: Variable Virulence Genes in Clinical Isolates of Burkholderia pseudomallei: Impact on Disease Severity and Outcome in Melioidosis
Variable Virulence Genes in Clinical Isolates of Burkholderia pseudomallei: Impact on Disease Severity and Outcome in Melioidosis Open
Objectives To isolate Burkholderia pseudomallei from clinical specimens and study the association of virulence genes with clinical manifestations and outcome in patients with melioidosis. Materials and Methods Burkholderia pseudomallei iso…
View article: The BinaxNOW antigen detection assay on CSF samples for diagnosis of pneumococcal meningitis
The BinaxNOW antigen detection assay on CSF samples for diagnosis of pneumococcal meningitis Open
Introduction The BinaxNOW pneumococcal antigen detection assay is an immuno-chromatographic technique where the cell wall polysaccharide instead of capsular polysaccharide is the target. Although intended for use on urine samples, its role…
View article: Usefulness of quantitative Loop-Mediated Isothermal Amplification Assay in comparison with real time PCR for the diagnosis of invasive pneumococcal disease
Usefulness of quantitative Loop-Mediated Isothermal Amplification Assay in comparison with real time PCR for the diagnosis of invasive pneumococcal disease Open
Background Quantitative LAMP (qLAMP) assay is one of the recent and emerging diagnostic tests for infectious diseases. Only a few studies exist comparing this assay with quantitative real-time PCR (qPCR) for the diagnosis of invasive pneum…
View article: Rare and unexpected cause for isolated massive pericardial effusion in a patient with end-stage renal disease—Brucellosis
Rare and unexpected cause for isolated massive pericardial effusion in a patient with end-stage renal disease—Brucellosis Open
Brucellosis is one of the most common zoonotic infections with worldwide distribution. The clinical presentation of brucellosis ranges from asymptomatic to severe disease involving haematological, gastrointestinal, neurological and osteoar…
View article: <xhtml:span xmlns:xhtml="http://www.w3.org/1999/xhtml" xml:lang="en">A rare and fatal case of puerperal sepsis due to&#160;<em>Burkholderia pseudomallei</em></xhtml:span>
A rare and fatal case of puerperal sepsis due to <em>Burkholderia pseudomallei</em> Open
Introduction : Melioidosis is an emerging life threatening infectious disease caused by Gram negative bacilli Burkholderia pseudomallei found in contaminated soil and surface ground water . It often presents with varied clinical manifestat…
View article: Emergence of CC17 vancomycin variable <i>Enterococcus faecium</i> in India
Emergence of CC17 vancomycin variable <i>Enterococcus faecium</i> in India Open
Vancomycin variable enterococci (VVE) are those isolates that are susceptible to glycopeptide like vancomycin but harbour the resistance determinants like vanA gene. Globally the emergence of such strains was reported, and from India our c…
View article: Estimation of seroprevalence of melioidosis among adult high risk groups in Southeastern India by indirect Hemagglutination assay
Estimation of seroprevalence of melioidosis among adult high risk groups in Southeastern India by indirect Hemagglutination assay Open
Burkholderia pseudomallei is an environmental saprophyte known to cause melioidosis, a disease endemic in northern Australia and Southeast Asia. With the increasing number of melioidosis cases, there is a lack of data on seroprevalence rat…
View article: Poor Sensorium at the Time of Intubation Predicts Polymicrobial Ventilator Associated Pneumonia
Poor Sensorium at the Time of Intubation Predicts Polymicrobial Ventilator Associated Pneumonia Open
Ramachandran Natarajan,1 Venkateswaran Ramanathan,1 Sujatha Sistla2 1Department of Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India; 2Department of Microbiology, Jawaharlal Institute of Postg…
View article: Detection of vancomycin variable enterococci (VVE) among clinical isolates of Enterococcus faecium collected across India-first report from the subcontinent
Detection of vancomycin variable enterococci (VVE) among clinical isolates of Enterococcus faecium collected across India-first report from the subcontinent Open
Although the prevalence is low, our finding emphasizes the importance of routinely screening for van genes in enterococci that are phenotypically susceptible. Silenced vanA able to escape detection and revert to resistance during vancomyci…
View article: Successful Isolation of Burkholderia pseudomallei from Soil by Extended Incubation of Ashdown’s Agar: A Cross-sectional Study
Successful Isolation of Burkholderia pseudomallei from Soil by Extended Incubation of Ashdown’s Agar: A Cross-sectional Study Open
Introduction: Melioidosis is an infectious disease of humans and animals caused by an environmental saprophyte Burkholderia pseudomallei. Although the organism is associated with soil and water, environmental isolation is rarely successful…
View article: An Eight Year Clinico-Microbiological Retrospective Study on Brain Abscesses in India
An Eight Year Clinico-Microbiological Retrospective Study on Brain Abscesses in India Open
Background: Intracranial abscesses have been a diagnostic and therapeutic challenge since time immemorial for both the microbiologists and the neurosurgeons. There is paucity of detailed studies documenting the infecting organism causing b…
View article: Association between Serum Antibody Titers against Influenza Viruses and the Risk of Influenza in Patients with Chronic Respiratory Diseases - a Prospective, Longitudinal Study
Association between Serum Antibody Titers against Influenza Viruses and the Risk of Influenza in Patients with Chronic Respiratory Diseases - a Prospective, Longitudinal Study Open
Introduction: Patients with respiratory co-morbidities are the primary target group for influenza vaccination as chronic respiratory diseases pose a serious risk for unvaccinated individuals during influenza season. According to Centers fo…