Sujin Park
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View article: Development of an RT-LAMP−CRISPR/Cas12a assay for rapid and specific detection of Bandavirus dabieense
Development of an RT-LAMP−CRISPR/Cas12a assay for rapid and specific detection of Bandavirus dabieense Open
Bandavirus dabieense, a single-stranded RNA virus, is the causative agent of severe fever with thrombocytopenia syndrome (SFTS), a disease associated with high fatality rates. Early and accurate diagnosis is essential for improving clinica…
View article: Biomimetic Salivary Gland Cancer Spheroid Platform for In Vitro Recapitulation of Three-Dimensional Tumor–Stromal Interactions
Biomimetic Salivary Gland Cancer Spheroid Platform for In Vitro Recapitulation of Three-Dimensional Tumor–Stromal Interactions Open
Salivary gland carcinomas (SGCs) are aggressive malignancies with limited treatment options, primarily due to the complexity of the tumor microenvironment (TME). Cancer-associated fibroblasts (CAFs) remodel the extracellular matrix (ECM), …
View article: In Situ X-ray Diffraction During Ball Milling Reveals Poorly Crystalline Metastable Intermediates During the Formation of Disordered Rocksalt Oxyfluorides
In Situ X-ray Diffraction During Ball Milling Reveals Poorly Crystalline Metastable Intermediates During the Formation of Disordered Rocksalt Oxyfluorides Open
Li-excess transition metal disordered rocksalt oxyfluorides continue to attract attention as next-generation cathode materials for Li-ion batteries. To this end, high-energy ball milling is the most versatile synthesis method for disordere…
View article: In Situ X-ray Diffraction During Ball Milling Reveals Poorly Crystalline Metastable Intermediates During the Formation of Disordered Rocksalt Oxyfluorides
In Situ X-ray Diffraction During Ball Milling Reveals Poorly Crystalline Metastable Intermediates During the Formation of Disordered Rocksalt Oxyfluorides Open
Li-excess transition metal disordered rocksalt oxyfluorides continue to attract attention as next-generation cathode materials for Li-ion batteries. High-energy ball milling is the most versatile synthesis method for disordered rocksalt ca…
View article: Cancer stem cells: landscape, challenges and emerging therapeutic innovations
Cancer stem cells: landscape, challenges and emerging therapeutic innovations Open
Cancer stem cells (CSCs) constitute a highly plastic and therapy-resistant cell subpopulation within tumors that drives tumor initiation, progression, metastasis, and relapse. Their ability to evade conventional treatments, adapt to metabo…
View article: The impact of selcopintide on periodontal regeneration in a class II furcation defect model: a radiographic and histomorphometric analysis
The impact of selcopintide on periodontal regeneration in a class II furcation defect model: a radiographic and histomorphometric analysis Open
Objectives This study investigated the effect of Selcopintide (SCPT) on periodontal regeneration using surgically created class II furcation defects in an animal model, employing both radiographical and histological evaluations. Materials …
View article: Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation
Tm4sf19 inhibition ameliorates inflammation and bone destruction in collagen-induced arthritis by suppressing TLR4-mediated inflammatory signaling and abnormal osteoclast activation Open
Rheumatoid arthritis (RA) is an autoimmune disease characterized by inflammation and abnormal osteoclast activation, leading to bone destruction. We previously demonstrated that the large extracellular loop (LEL) of Tm4sf19 is important fo…
View article: Effects of SGLT2 Inhibitors on Cardiovascular and Lower Limb Events in Patients with Type 2 Diabetes: A Nationwide Population-Based Study
Effects of SGLT2 Inhibitors on Cardiovascular and Lower Limb Events in Patients with Type 2 Diabetes: A Nationwide Population-Based Study Open
In this nationwide, real-world study, SGLT2i use demonstrated a neutral effect on LLEs compared to DPP-4i in patients with type 2 diabetes. However, SGLT2i was associated with a lower risk of all-cause mortality, heart failure, ischemic st…
View article: Empagliflozin Attenuates High-Glucose-Induced Astrocyte Activation and Inflammation via NF-κB Pathway
Empagliflozin Attenuates High-Glucose-Induced Astrocyte Activation and Inflammation via NF-κB Pathway Open
Sodium-glucose cotransporter-2 (SGLT2) inhibitors regulate blood glucose levels in patients with type 2 diabetes mellitus and may also exert anti-inflammatory and anti-atherosclerotic effects by promoting M2 macrophage polarization. Althou…
View article: Gastric-type extremely well-differentiated adenocarcinoma of the stomach: A rare tumor with diagnostic difficulties and high inter-observer variation in endoscopic pinch biopsies
Gastric-type extremely well-differentiated adenocarcinoma of the stomach: A rare tumor with diagnostic difficulties and high inter-observer variation in endoscopic pinch biopsies Open
Extremely well-differentiated gastric-type adenocarcinoma (EWDGA) is a rare type of gastric cancer composed of deceptively bland-looking malignant cells resembling normal foveolar or pyloric epithelium. The histological features of this tu…
View article: Numerical study on the internal ventilation of the engine room of a ship under construction
Numerical study on the internal ventilation of the engine room of a ship under construction Open
Manual welding operations are performed inside the engine room of a liquefied natural gas carrier under construction. The welders are at risk of exposure to welding fumes in case of poor ventilation. Therefore, ventilation fans are install…
View article: Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges
Advances in mass spectrometry-based approaches for characterizing monoclonal antibodies: resolving structural complexity and analytical challenges Open
Mass spectrometry (MS)-based intact mass analysis and structural characterization of biotherapeutic proteins such as monoclonal antibodies (mAbs) are a crucial characterization approach from upstream drug development to downstream product …
View article: Featured Cover
Featured Cover Open
Cover legend: The cover image is based on the Research Article Cpne7 deficiency induces cellular senescence and premature aging of dental pulp by Yoon Seon Lee et al., https://doi.org/10.1111/acel.14061 [Image: see text]
View article: Cpne7 deficiency induces cellular senescence and premature aging of dental pulp
Cpne7 deficiency induces cellular senescence and premature aging of dental pulp Open
Once tooth development is complete, odontoblasts and their progenitor cells in the dental pulp play a major role in protecting tooth vitality from external stresses. Hence, understanding the homeostasis of the mature pulp populations is ju…
View article: The anti‐cancer effect of <scp>epigallocatechin‐3‐</scp> <i>O</i> ‐gallate against multiple myeloma cells is potentiated by 5,7‐dimethoxyflavone
The anti‐cancer effect of <span>epigallocatechin‐3‐</span> <i>O</i> ‐gallate against multiple myeloma cells is potentiated by 5,7‐dimethoxyflavone Open
(−)‐Epigallocatechin‐3‐ O ‐gallate (EGCG) is one of the major components of green tea polyphenol. Previous studies have shown that EGCG induces cancer‐specific cell death in vitro and in vivo without causing severe side effects. However, t…
View article: N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer
N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer Open
KIAA1324 is a transmembrane protein largely reported as a tumor suppressor and favorable prognosis marker in various cancers, including gastric cancer. In this study, we report the role of N-linked glycosylation in KIAA1324 as a functional…
View article: Integrative structural analysis of disease-related proteins using SAXS and X-ray crystallography
Integrative structural analysis of disease-related proteins using SAXS and X-ray crystallography Open
is a very powerful tool for the structural and biophysical study of
View article: N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer
N-linked glycosylation is essential for anti-tumor activities of KIAA1324 in gastric cancer Open
KIAA1324 is a transmembrane protein reported largely as a tumor suppressor and favorable prognosis marker in various cancers, including gastric cancer. In this study, we report the role of N-linked glycosylation in KIAA1324 as a functional…
View article: Data from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78
Data from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78 Open
Recent advances in genome and transcriptome analysis have contributed to the identification of many potential cancer-related genes. Furthermore, biological and clinical investigations of the candidate genes provide us with a better underst…
View article: Supplementary Materials and Methods from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78
Supplementary Materials and Methods from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78 Open
Supplementary Materials and Methods
View article: Supplementary Materials and Methods from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78
Supplementary Materials and Methods from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78 Open
Supplementary Materials and Methods
View article: Supplementary Figures S1-S13 and Table S1 from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78
Supplementary Figures S1-S13 and Table S1 from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78 Open
Supplementary Figures S1-S13 and Table S1. Confirmation of KIAA1324 mRNA expression in primary tissues from gastric cancer (GC) patients and GC cell lines (S1). Analysis of correlation between copy number variation (CNV) and KIAA1324 mRNA …
View article: Supplementary Figures S1-S13 and Table S1 from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78
Supplementary Figures S1-S13 and Table S1 from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78 Open
Supplementary Figures S1-S13 and Table S1. Confirmation of KIAA1324 mRNA expression in primary tissues from gastric cancer (GC) patients and GC cell lines (S1). Analysis of correlation between copy number variation (CNV) and KIAA1324 mRNA …
View article: Data from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78
Data from KIAA1324 Suppresses Gastric Cancer Progression by Inhibiting the Oncoprotein GRP78 Open
Recent advances in genome and transcriptome analysis have contributed to the identification of many potential cancer-related genes. Furthermore, biological and clinical investigations of the candidate genes provide us with a better underst…
View article: Prognostic Significance of Esophagogastric Junction Invasion in Patients with Adenocarcinoma of the Cardia or Subcardia
Prognostic Significance of Esophagogastric Junction Invasion in Patients with Adenocarcinoma of the Cardia or Subcardia Open
Background: There has been no comparison of the prognoses of Korean patients who underwent curative surgery for cancer located at the cardia or subcardia of the stomach. We performed this comparison and further investigated the prognostic …
View article: Dietary replacement of Undaria pinnatifida by Sargassum horneri in feed formulation for abalone Haliotis discus hannai: Effect on growth, gut microbiota, and taste sensory profile
Dietary replacement of Undaria pinnatifida by Sargassum horneri in feed formulation for abalone Haliotis discus hannai: Effect on growth, gut microbiota, and taste sensory profile Open
The necessity for additional macroalgal biomass is warranted amid the ongoing expansion of abalone aquaculture. In the current study, an in-depth investigation of the food value of Sargassum horneri as a replacement for Undaria pinnatifida…