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View article: A community-oriented, data-driven resource to improve protocol design for cardiac modelling from human pluripotent stem cells
A community-oriented, data-driven resource to improve protocol design for cardiac modelling from human pluripotent stem cells Open
Protocols for culturing cardiac cells derived from human-induced pluripotent stem cells (hiPSCs) are critical for studying mechanisms of development and disease. This study provides data-driven analysis of a community-oriented database to …
View article: CMPortal: a community-oriented, data-driven resource to inform protocol design for cardiac modelling from human pluripotent stem cells
CMPortal: a community-oriented, data-driven resource to inform protocol design for cardiac modelling from human pluripotent stem cells Open
Protocol design and benchmarking is central to optimising model development using human pluripotent stem cell derived cardiomyocytes (hPSC-CMs). By applying data mining to decades of research and hundreds of peer reviewed studies, we evalu…
View article: A pluripotent stem cell atlas of multilineage differentiation reveals<i>TMEM88</i>as a developmental regulator of mammalian blood pressure
A pluripotent stem cell atlas of multilineage differentiation reveals<i>TMEM88</i>as a developmental regulator of mammalian blood pressure Open
SUMMARY Pluripotent stem cells provide a scalable approach to analyse molecular regulation of cell differentiation across multiple developmental lineage trajectories. In this study, we engineered barcoded iPSCs to generate an atlas of mult…