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View article: Regulation of Milk Production by the MAPK/ERK Pathway in Water Buffalo ( <i>Bubalus bubalis)</i> : Genomic and Molecular Insights
Regulation of Milk Production by the MAPK/ERK Pathway in Water Buffalo ( <i>Bubalus bubalis)</i> : Genomic and Molecular Insights Open
The MAPK/ERK pathway plays a critical role in the regulation of milk production by controlling cellular processes such as proliferation, differentiation and survival, which are essential for lactogenesis and mammary gland function. Bubalus…
View article: Labor, technology, and growth as determinants of CO2 emissions: evidence from trade-intensive economies
Labor, technology, and growth as determinants of CO2 emissions: evidence from trade-intensive economies Open
This study evaluates the impact of labour force participation rate, advanced technology, and GDP growth on CO2 emissions in highly trade-open economies. The analysis is framed within the Environmental Kuznets Curve and Pollution Haven Hypo…
View article: The Smart Librarian: AI Skills for the Modern Era
The Smart Librarian: AI Skills for the Modern Era Open
Background: The rapid adoption of Artificial Intelligence (AI) is changing the library and information services and automates the main processes and introduces new principles of user interaction and accessibility. This change in technology…
View article: Development of Urdu Version of Gross Motor Family Report (GMF-FR) Scoresheet; Validity and Reliability Analysis in Cerebral Palsy Children
Development of Urdu Version of Gross Motor Family Report (GMF-FR) Scoresheet; Validity and Reliability Analysis in Cerebral Palsy Children Open
Background: Cerebral palsy is the most prevalent physical disability in children, with significant implications for motor function and quality of life. Reliable caregiver-reported outcome measures are important for evaluating function in e…
View article: Investigating the role of FOX gene family in development and stress response in Labeo rohita: A multi-faceted analysis of phylogeny and genome characterization
Investigating the role of FOX gene family in development and stress response in Labeo rohita: A multi-faceted analysis of phylogeny and genome characterization Open
The forkhead box (FOX) gene family of transcription factors regulates muscle development, immune responses, and metabolic processes across species. Despite extensive studies on FOX genes in other organisms, their evolutionary and functiona…
View article: A Study on the Dynamic Impact of Instructional Leadership on Enhancing Elementary School Performance in Baluchistan
A Study on the Dynamic Impact of Instructional Leadership on Enhancing Elementary School Performance in Baluchistan Open
This study explores the dynamic impact of instructional leadership on enhancing the performance of elementary schools in Baluchistan, aligning with Sustainable Development Goal (SDG) 4, which promotes inclusive and equitable quality educat…
View article: Genomic Adaptation, Environmental Challenges, and Sustainable Yak Husbandry in High-Altitude Pastoral Systems
Genomic Adaptation, Environmental Challenges, and Sustainable Yak Husbandry in High-Altitude Pastoral Systems Open
The yak (Bos grunniens) is a key species in high-altitude rangelands of Asia. Despite their ecological and economic importance, yak production faces persistent challenges, including low milk yields, vulnerability to climate changes, emergi…
View article: Environmental relevant concentrations of copper sulphate induce biochemical and molecular toxicity in Labeo rohita
Environmental relevant concentrations of copper sulphate induce biochemical and molecular toxicity in Labeo rohita Open
Copper is an important element involved in the catalysis of many vital reactions in the body of an organism. However, excessive copper causes cellular damage by accelerating the production of reactive oxygen species and disrupting the phys…
View article: Assessing Atraumatic Versus Conventional Restorative Treatment For Dental Caries In Deciduous Molars: A Comparative Study
Assessing Atraumatic Versus Conventional Restorative Treatment For Dental Caries In Deciduous Molars: A Comparative Study Open
Background: Dental caries is common problem seen in children. Treatment options such as atraumatic and conventional restorative techniques are usually performed among such children. This study aimed to determine the success rate associated…
View article: Efficacy of 4% Articaine vs 2% Lidocaine in Mandibular and Maxillary Block and Infiltration Anesthesia in Patients with Irreversible Pulpitis
Efficacy of 4% Articaine vs 2% Lidocaine in Mandibular and Maxillary Block and Infiltration Anesthesia in Patients with Irreversible Pulpitis Open
Background: Achieving effective anesthesia in patients with irreversible pulpitis remains a significant clinical challenge, particularly in mandibular molars, as standard inferior alveolar nerve blocks with lidocaine frequently fail due to…
View article: Clinical Assessment of Bonding Agent Versus Fluoride Varnish in Dental Hypersensitivity
Clinical Assessment of Bonding Agent Versus Fluoride Varnish in Dental Hypersensitivity Open
Background: Dental hypersensitivity is a prevalent condition characterized by transient, sharp pain from exposed dentin, significantly impacting quality of life. Objective: This study aimed to compare the effectiveness, patient satisfactio…
View article: Exploration of Natural Preservative Systems for Enhancing Microbial Stability and Shelf Life in Dairy-Based Food Matrices
Exploration of Natural Preservative Systems for Enhancing Microbial Stability and Shelf Life in Dairy-Based Food Matrices Open
Interest in natural preservative systems has increased due to the need for clean-label and chemical-free food items, especially when it comes to dairy-based food matrices that are extremely vulnerable to microbial spoiling. The many natura…
View article: The Perception of Smile Arc and Buccal Corridor in Medical and Dental Undergraduate Students of Peshawar, Pakistan: A Descriptive Cross-sectional Study
The Perception of Smile Arc and Buccal Corridor in Medical and Dental Undergraduate Students of Peshawar, Pakistan: A Descriptive Cross-sectional Study Open
Objective: To compare smile aesthetics perceptions, focusing on components such as smile arc and buccalcorridor, between pre-clinical medical and dental students.Study Design: A descriptive cross-sectional study.Place and Duration of Study…
View article: ISSUES AND CHALLENGES OF SEXUAL HARASSMENT IN WOMEN POLICE: A CROSS-SECTIONAL STUDY OF POLICE IN PAKISTAN
ISSUES AND CHALLENGES OF SEXUAL HARASSMENT IN WOMEN POLICE: A CROSS-SECTIONAL STUDY OF POLICE IN PAKISTAN Open
The purpose of study is to illustrate sexual harassment as one of the burning issues and challenges which the Women Police often encounter in Pakistan. The Design comprises of sample containing cross-section of influencing persons from soc…
View article: Anesthetic Effectiveness of Buccal Infiltration Alone Vs Combined Buccal and Palatal Infiltration on Symptomatic Maxillary Teeth
Anesthetic Effectiveness of Buccal Infiltration Alone Vs Combined Buccal and Palatal Infiltration on Symptomatic Maxillary Teeth Open
Objective: To evaluate the effectiveness of two distinct methods of local anesthesia. The effects of buccal and palatal infiltration with pulpal anesthesia on symptomatic maxillary molars (Maxillary first, and second molar) were compared w…
View article: Trace elements in fish species from the Punjnad headworks: Bioaccumulation and human health risk assessment
Trace elements in fish species from the Punjnad headworks: Bioaccumulation and human health risk assessment Open
Aquatic toxicology, as a result of industrial and agrieqcultural effluences, has become a global concern impacting not only the well-being of aquatic organisms but human health as well. The current study evaluated the impact of four toxic …
View article: Morphological and Genetic Identification of Fish Species of River Ravi, Pakistan
Morphological and Genetic Identification of Fish Species of River Ravi, Pakistan Open
DNA barcoding is a method that examines a specific part of the mitochondrial genome known as the cytochrome c oxidase subunit I (COI) gene, for species identification and biodiversity studies. The current study assessed the effectiveness o…
View article: Management of Diabetic Foot Ulcer - A Case Report
Management of Diabetic Foot Ulcer - A Case Report Open
Due to sedentary lifestyle of today, diabetes mellitus is becoming a common illness. One of the complications of diabetes mellitus, the primary cause of lower limb amputations, is diabetic foot ulcers. It affects 15% of all diabetes mellit…
View article: Governance and Sustainable Development: The Role of Environmental Performance at the Country Level
Governance and Sustainable Development: The Role of Environmental Performance at the Country Level Open
The objective of this study is to examine the role of environmental performance and governance in promoting sustainable development. This study employs secondary data spanning from 2015 to 2022 from different sources, including the World G…
View article: Determinant genetic markers of semen quality in livestock
Determinant genetic markers of semen quality in livestock Open
The reproductive efficiency of livestock is crucial for agricultural productivity and economic sustainability. One critical factor in successful fertilization and the viability of offspring is the quality of semen. Poor semen quality, espe…
View article: Trace Elements in Fish: Assessment of bioaccumulation and associated health risks.
Trace Elements in Fish: Assessment of bioaccumulation and associated health risks. Open
Industrial and agricultural water run-off are polluting the aquatic ecosystem by depositing different toxic trace elements (TTEs) in riverine system. It has become a global concern impacting not only the well-being of aquatic organisms but…
View article: Toxic Effects of Lead Chloride (PbCl2) on Behavioral, Hematological, and Serum Biochemical Parameters in Labeo rohita
Toxic Effects of Lead Chloride (PbCl2) on Behavioral, Hematological, and Serum Biochemical Parameters in Labeo rohita Open
Background. Lead (Pb) is an extremely toxic metal in aqueous environments. Fish are highly susceptible to the lethal effects of lead exposure since it induces toxicity in fish, with oxidative stress causing neurotoxicity. Moreover, lead af…
View article: In vitro study of antioxidant and antimicrobial potential of Moringa oleifera leaves as a green food preservative in chicken burger
In vitro study of antioxidant and antimicrobial potential of Moringa oleifera leaves as a green food preservative in chicken burger Open
Moringa oleifera L. (from the Moringaceae family) is highly valued for its rich nutritional profile, phytochemical composition, and abundance of crucial vitamins and minerals.This study aimed to investigate the impact of bioactive compound…
View article: Introduction to Drug Repurposing: Exploring New Applications for Existing Drugs
Introduction to Drug Repurposing: Exploring New Applications for Existing Drugs Open
This chapter delves into the concept of drug repurposing, which involves identifying new therapeutic applications for existing drugs. Drug repurposing offers a cost-effective and time-efficient approach to drug discovery by leveraging the …
View article: Unraveling the ecotoxicological effects of micro and nano-plastics on aquatic organisms and human health
Unraveling the ecotoxicological effects of micro and nano-plastics on aquatic organisms and human health Open
Plastic pollution ranks among the most severe environmental disasters caused by humans, generating millions of tonnes of waste annually. The extensive and unregulated use of plastics has led to ecotoxicity and environmental imbalance. Micr…
View article: Behavioral and Hematological Alterations in Grass Carp (Ctenopharyngodon idella) Exposed to Bifenthrin
Behavioral and Hematological Alterations in Grass Carp (Ctenopharyngodon idella) Exposed to Bifenthrin Open
Insecticides are used across the world as it is evaluated that poses a risk to aquatic life especially fish, which are very sensitive in response to change in environmental conditions.The current study evaluated the effects of bifenthrin o…