Sun-Yeon Heo
YOU?
Author Swipe
View article: High production of glycolic acid by Klebsiella pneumoniae: Engineering metabolic pathways and optimizing culture conditions
High production of glycolic acid by Klebsiella pneumoniae: Engineering metabolic pathways and optimizing culture conditions Open
Growing concerns regarding environmental pollution caused by non-biodegradable plastic waste have intensified the demand for sustainable biodegradable bioplastics. Glycolic acid (GA), the monomer of polyglycolic acid (PGA), is a key precur…
View article: Identification and fermentation optimization of a newly isolated strain Bacillus velezensis AmoreLumina for high-yield moranoline production
Identification and fermentation optimization of a newly isolated strain Bacillus velezensis AmoreLumina for high-yield moranoline production Open
Moranoline (1-Deoxynojirimycin), a rare iminosugar with α-glucosidase inhibitory activity, holds promise as a candidate for diabetes treatment due to its pharmacological properties. However, moranoline is typically found in trace amounts i…
View article: Sustainable production of a highly pure (R,R)-2,3-butanediol from crude glycerol using metabolically engineered Klebsiella pneumoniae GEM167 strain
Sustainable production of a highly pure (R,R)-2,3-butanediol from crude glycerol using metabolically engineered Klebsiella pneumoniae GEM167 strain Open
Background Among 2,3-butanediol (2,3-BDO) stereoisomers, (R,R)-2,3-BDO is particularly noteworthy for its application in the agricultural industry. It is an eco-friendly plant immune system stimulant, promoting plant growth and enhancing r…
View article: Evaluation of mathematical models for predicting medicine distribution into breastmilk - considering biological heterogeneity
Evaluation of mathematical models for predicting medicine distribution into breastmilk - considering biological heterogeneity Open
Introduction A significant proportion of mothers take medication during the breastfeeding period, however knowledge of infant safety during continued breastfeeding is often limited. Breastmilk exhibits significant physiological heterogenei…
View article: Selective production of two prebiotic extracellular polysaccharides from an oral probiotic lactic acid bacterium, Streptococcus salivarius SY511
Selective production of two prebiotic extracellular polysaccharides from an oral probiotic lactic acid bacterium, Streptococcus salivarius SY511 Open
Streptococcus salivarius is a lactic acid bacterium and an oral probiotic species. Growth of S. salivarius in a sucrose medium can lead to the production of exopolysaccharides (EPSs) that are potential prebiotics. However, no studies have …
View article: Efficient production of isobutanol from glycerol in Klebsiella pneumoniae: Regulation of acetohydroxyacid synthase, a rate-limiting enzyme in isobutanol biosynthesis
Efficient production of isobutanol from glycerol in Klebsiella pneumoniae: Regulation of acetohydroxyacid synthase, a rate-limiting enzyme in isobutanol biosynthesis Open
Glycerol is an abundant and inexpensive resource that can be used to produce valuable industrial products. Isobutanol is an important industrial chemical that has been studied for biosynthesis from various carbon sources and microorganisms…
View article: Synbiotics production using Lactobacillus reuteri EC01, a strain that produces alternan-type exopolysaccharide
Synbiotics production using Lactobacillus reuteri EC01, a strain that produces alternan-type exopolysaccharide Open
Alternan is an α-glucan polysaccharide with a unique structure that has promise for use as a prebiotic. In this study, we isolated a novel strain of Lactobacillus reuteri BR120 that produces abundant exopolysaccharides (EPSs). Monosacchari…
View article: Efficient production of isobutanol from glycerol in Klebsiella pneumoniae: Regulation of acetohydroxyacid synthase, a rate-limiting enzyme in isobutanol biosynthesis at gene expression level
Efficient production of isobutanol from glycerol in Klebsiella pneumoniae: Regulation of acetohydroxyacid synthase, a rate-limiting enzyme in isobutanol biosynthesis at gene expression level Open
Background: Glycerol is inexpensive and abundant, and can be used for the industrial production of value-added products. Isobutanol is an important industrial chemical that has many applications, and its biosynthesis from different carbon …
View article: The Biocatalytic Production of 3-Hydroxypropionaldehyde and Evaluation of Its Stability
The Biocatalytic Production of 3-Hydroxypropionaldehyde and Evaluation of Its Stability Open
3-Hydroxypropionaldehyde (3-HPA, reuterin) is a broad-spectrum natural antimicrobial agent used in the food industry and other fields. The low yield from the industrial production of 3-HPA using Lactobacillus reuteri and the spontaneous co…
View article: Effective bioconversion of 1,3-propanediol from biodiesel-derived crude glycerol using organic acid resistance–enhanced Lactobacillus reuteri JH83
Effective bioconversion of 1,3-propanediol from biodiesel-derived crude glycerol using organic acid resistance–enhanced Lactobacillus reuteri JH83 Open
Organic acids produced during the fermentation of lactic acid bacteria inhibit cellular growth and the production of 1,3-propanediol (1,3-PDO). Lactobacillus reuteri JH83, which has an increase of 18.6% in organic acid resistance, was obta…
View article: Synthesis of two new lipid mediators from docosahexaenoic acid by combinatorial catalysis involving enzymatic and chemical reaction
Synthesis of two new lipid mediators from docosahexaenoic acid by combinatorial catalysis involving enzymatic and chemical reaction Open
Omega-3 polyunsaturated fatty acids (PUFAs) have been known to have beneficial effects in the prevention of various diseases. Recently, it was identified that the bioactivities of omega-3 are related to lipid mediators, called pro-resolvin…
View article: Enhancement of 1,3-propanediol production from industrial by-product by Lactobacillus reuteri CH53
Enhancement of 1,3-propanediol production from industrial by-product by Lactobacillus reuteri CH53 Open
Background 1,3-propanediol (1,3-PDO) is the most widely studied value-added product that can be produced by feeding glycerol to bacteria, including Lactobacillus sp. However, previous research reported that L . reuteri only produced small …
View article: Simultaneous Overpexpression of Genes Encoding Cellulose- and Xylan-Degrading Enzymes through High Density Culture of a Recombinant Yeast Cell
Simultaneous Overpexpression of Genes Encoding Cellulose- and Xylan-Degrading Enzymes through High Density Culture of a Recombinant Yeast Cell Open
자연계에서 cellulase와 xylanase의 기본 기능은 식물 세포 벽의 주요 구성물질인 cellulose와 xylan의 β-1,4-glycosidic linkage를 절단하여 구성 당으로 분해함으로써 생물체가 에 너지원과 탄소원으로 이용할 수 있도록 하는 것이다[1, 2].따라서 cellulase와 xylanase는 광합성에 의해 고정된 carbon의 recycling에 주요한 역할을 수행한다.자연계에 존 재하는 fix…