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View article: RAB25 modulates pit cell commitment by coordinating transforming growth factor-alpha secretion from gastric epithelial cells
RAB25 modulates pit cell commitment by coordinating transforming growth factor-alpha secretion from gastric epithelial cells Open
EGFR signaling serves as a regulator of lineage commitment in the stomach. A recent study revealed that two different EGFR ligands can induce fate determination of isthmus progenitors in corpus, but the source and regulatory mechanism of t…
View article: Adult K18-hACE2 mice are suitable for studying intranasal SARS-CoV-2 infection but not direct-contact transmission
Adult K18-hACE2 mice are suitable for studying intranasal SARS-CoV-2 infection but not direct-contact transmission Open
The rapid global spread of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) since 2019 emphasizes the need to understand its transmission routes, which mainly comprise airborne and contact transmission. Contact transmission, wh…
View article: A New Murine Liver Fibrosis Model Induced by Polyhexamethylene Guanidine-Phosphate
A New Murine Liver Fibrosis Model Induced by Polyhexamethylene Guanidine-Phosphate Open
Liver fibrosis is part of the wound healing process to help the liver recover from the injuries caused by various liver-damaging insults. However, liver fibrosis often progresses to life-threatening cirrhosis and hepatocellular carcinoma. …
View article: Ex Vivo Live Full-Thickness Porcine Skin Model as a Versatile In Vitro Testing Method for Skin Barrier Research
Ex Vivo Live Full-Thickness Porcine Skin Model as a Versatile In Vitro Testing Method for Skin Barrier Research Open
Since the European Union (EU) announced their animal testing ban in 2013, all animal experiments related to cosmetics have been prohibited, creating a demand for alternatives to animal experiments for skin studies. Here, we investigated wh…