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SAFEHERE-KM: A prospective multicenter registry-based observational study protocol on the safety of postpartum herbal medicine in Korean medicine clinics Open
Background: Postpartum conditions significantly affect maternal and infant health. In South Korea, herbal medicine (HM) is commonly used for postpartum care in Korean Medicine (KM), but safety data on it remain limited. This study outlines…
Picoliter‐Volume Isothermal Titration Calorimetry Using Parylene Chip Calorimeter Integrated with on‐Demand Droplet Microfluidics Open
Isothermal titration calorimetry (ITC) is a gold‐standard technique for directly quantifying biomolecular interactions, but its broader applicability is limited by large sample consumption and low throughput. To address these challenges, c…
Specificity of Amino Acid Profiles Produced in Soybean Fermentations by Three <i>Bacillus</i> spp. Open
We compared the salt tolerance and proteolytic activity of 120 strains of each of Bacillus subtilis, Bacillus velezensis, and Bacillus licheniformis. Most B. subtilis strains exhibited growth in 12% (w/v) NaCl and showed proteolytic activi…
Class Granularity: How richly does your knowledge graph represent the real world? Open
To effectively manage and utilize knowledge graphs, it is crucial to have metrics that can assess the quality of knowledge graphs from various perspectives. While there have been studies on knowledge graph quality metrics, there has been a…
Effect of roasting and puffing on amino acid contents of Bacillus subtilis-fermented beans Open
Bacillus subtilis로 발효하는 백태, 병아리콩, 누에콩 3종류 콩의 구성아미노산 프로파일에 볶음 및 팽화 처리 도입이 미치는 영향을 검토하였다. 본 연구에서는 시료 처리 후 흡수량에 근거 볶음 온도와 시간을 120oC, 30분으로, 팽화 압력을 588 kPa로 결정하였다. 볶음 및 팽화 처리는 3종류 콩의 구성아미노산 함량비에 통계적으로 유의미한 영향을 미치지 못했지만, 발효는 비처리 대비 arginine, as…
Regulation of anti-inflammatory and antioxidant responses by methanol extract of Mikania cordata (Burm. f.) B. L. Rob. leaves via the inactivation of NF-κB and MAPK signaling pathways and activation of Nrf2 in LPS-induced RAW 264.7 macrophages Open
Mikania cordata (Burm. f.) B.L. Rob. has been traditionally used in tropical countries throughout Asia and Africa to treat gastric ulcers, dyspepsia, and dysentery. However, the mechanisms responsible for its anti-inflammatory and antioxid…
ELVIS: Empowering Locality of Vision Language Pre-training with Intra-modal Similarity Open
Deep learning has shown great potential in assisting radiologists in reading chest X-ray (CXR) images, but its need for expensive annotations for improving performance prevents widespread clinical application. Visual language pre-training …
Genomic insight into the salt tolerance and proteolytic activity of <i>Bacillus subtilis</i> Open
We assessed the salt tolerance and proteolytic activity of 40 genome-published Bacillus subtilis strains isolated from fermented Korean foods to illuminate the genomic background behind the functionality of B. subtilis in high-salt ferment…
Structural Quality Metrics to Evaluate Knowledge Graphs Open
This work presents six structural quality metrics that can measure the quality of knowledge graphs and analyzes five cross-domain knowledge graphs on the web (Wikidata, DBpedia, YAGO, Google Knowledge Graph, Freebase) as well as 'Raftel', …
Anti-inflammatory and antioxidant activities of methanol extract of Piper betle Linn. (Piper betle L.) leaves and stems by inhibiting NF-κB/MAPK/Nrf2 signaling pathways in RAW 264.7 macrophages Open
Oxidative stress and chronic inflammation are closely linked to various diseases. However, previous studies have demonstrated that plant extracts could prevent and alleviate these adverse outcomes. Piper betle Linn. (Piper betle L.) is a c…
FantasyCoref: Coreference Resolution on Fantasy Literature Through Omniscient Writer’s Point of View Open
This paper presents a new corpus and annotation guideline for a novel coreference resolution task on fictional texts, and analyzes its unique characteristics. FantasyCoref contains 211 stories of Grimms' Fairy Tales and 3 other fantasy lit…
Effect of Large Versus Small Range of Motion in the Various Intensities of Eccentric Exercise-Induced Muscle Pain and Strength Open
The purpose was to investigate eccentric (ECC) exercise with full range of motion (FROM) induce a greater magnitude of delayed onset muscle soreness (DOMS), pain, functional limitations compared to partial range of motion (PROM; outer 60° …
Development of high-sensitivity chip calorimeters for cellular metabolic heat sensing Open
Cellular metabolic rate is a good indicator of the physiological state of cells and its changes, which can be measured by total heat flux accompanying metabolism. Chip calorimeters can provide label-free and high throughput measurements of…
PDMS-Parylene Hybrid, Flexible Microfluidics for Real-Time Modulation of 3D Helical Inertial Microfluidics Open
Inertial microfluidics has drawn much attention for its applications for circulating tumor cell separations from blood. The fluid flows and the inertial particle focusing in inertial microfluidic systems are highly dependent on the channel…