Soumen Das
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View article: Study on interval Volterra integral equations via parametric approach of intervals
Study on interval Volterra integral equations via parametric approach of intervals Open
This work investigates the interval Volterra integral equation (IVIE) and its solution techniques through the parametric representation of intervals. First, the general form of the second-kind IVIE is expressed in both lower-upper bound fo…
View article: Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani
Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani Open
The management of Leishmania donovani (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug unresponsiveness, leading to increasing treatment failures. While hypolipidemia characterizes VL,…
View article: Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani
Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani Open
The management of Leishmania donovani (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment failures. While hypolipidemia characterizes VL,…
View article: The Role of Bisphosphonates in Preventing Fragility Fractures: A 10-Year Follow-Up Study
The Role of Bisphosphonates in Preventing Fragility Fractures: A 10-Year Follow-Up Study Open
Bisphosphonates serve as a pharmaceutical treatment to stop fractures among people who have osteoporosis which shows itself through reduced bone mineral density and elevated susceptibility to bone-breaking fractures. The purpose of this re…
View article: Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani
Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani Open
The management of Leishmania donovani (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug unresponsiveness, leading to increasing treatment failures. While hypolipidemia characterizes VL,…
View article: Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani
Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani Open
The management of Leishmania donovani (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment failures. While hypolipidemia characterizes VL,…
View article: Femoral Shortening Osteotomy in Managing Congenital Patellar Dislocation: A Case Report and Review of Literature
Femoral Shortening Osteotomy in Managing Congenital Patellar Dislocation: A Case Report and Review of Literature Open
Introduction: Congenital patellar dislocation is a very rare knee disorder characterized by the lateral dislocation of patella from birth, which cannot be reduced. The disorder affects both knees and is a persistent condition. Bony and sof…
View article: Micro-hydrogel molding-assisted fabrication of a PDMS-based microfluidic concentration-gradient generator for dynamic anticancer drug testing
Micro-hydrogel molding-assisted fabrication of a PDMS-based microfluidic concentration-gradient generator for dynamic anticancer drug testing Open
A frugal microfluidic concentration gradient generator was developed without the requirement of clean-room conditions. Device performance was validated theoretically and experimentally, and drug dose–response analysis was conducted on canc…
View article: Epidermal Growth Factor Receptor (EGFR) and SMAD4 negatively correlated in the progression of gallbladder cancer in Eastern Indian patients
Epidermal Growth Factor Receptor (EGFR) and SMAD4 negatively correlated in the progression of gallbladder cancer in Eastern Indian patients Open
EGFR and SMAD4 expression were found to be negatively correlated in GBC tissue samples. ERBB2 overexpression/amplification was observed in 30% of the GBC samples. We also found a low percentage of GBC samples to show KRAS codon 12 mutation…
View article: Design, Formulation, Physicochemical Characterization and In Vitro Evaluation of Alfuzosin HCL -Loaded Microspheres Using 3d Printing Technology
Design, Formulation, Physicochemical Characterization and In Vitro Evaluation of Alfuzosin HCL -Loaded Microspheres Using 3d Printing Technology Open
Introduction Alfuzosin hydrochloride, is an α₁-adrenergic antagonist, is widely used for the treatment of moderate to severe benign prostatic hyperplasia (BPH). While effective, its immediate-release (IR) formulations require multiple dail…
View article: Beyond Hemostasis: Understanding the Risks of Bone Wax in Orthopedic Surgery – A Case Report
Beyond Hemostasis: Understanding the Risks of Bone Wax in Orthopedic Surgery – A Case Report Open
Introduction: Osseous hemorrhage following a surgical incision or traumatic fracture can be a challenging issue to manage. During orthopedic surgeries, bone wax is frequently utilized as a surgical technique to enhance hemostasis and reduc…
View article: Differential expression of miRNAs between Young-Onset and Late-Onset Indian colorectal carcinoma patients
Differential expression of miRNAs between Young-Onset and Late-Onset Indian colorectal carcinoma patients Open
Early-Onset Colorectal Carcinoma (EOCRC) is a growing concern as reports indicate a worldwide increase in the incidence of CRC among young adults (55 years old) and screened them to eliminate tumors positive for Microsatellite Instability …
View article: Charge transfer mediated giant photo-amplification in air-stable $α$-CsPbI$_3$ nanocrystals decorated 2D-WS$_2$ photo-FET with asymmetric contacts
Charge transfer mediated giant photo-amplification in air-stable $α$-CsPbI$_3$ nanocrystals decorated 2D-WS$_2$ photo-FET with asymmetric contacts Open
Hybrid heterostructure based phototransistors are attractive owing to their high gain induced by photogating effect. However, the absence of an in-plane built-in electric field in the single channel layer transistor results in a relatively…
View article: Squigglebot: a battery powered spherical rolling robot as a model active matter system to measure its energetics
Squigglebot: a battery powered spherical rolling robot as a model active matter system to measure its energetics Open
Active matter systems use their internal or ambient source of energy and dissipate them at the scale of individual constituent particles to generate motion. Direct measurement of the energy influx for individual particles has not been achi…
View article: Enigmatic Entities of the Acellular World: Viruses, Viroids, and Virusoids
Enigmatic Entities of the Acellular World: Viruses, Viroids, and Virusoids Open
Genetic material confined within the lipid based cellular boundaries was earlier considered synonymous with life. However, with the discovery of viruses in late 19th century, the existence of acellular biological entities was established. …
View article: Transcolostomy colectomy: A stoma revision technique to treat complex stoma prolapse
Transcolostomy colectomy: A stoma revision technique to treat complex stoma prolapse Open
Colostomies are commonly performed operation in colorectal surgery. These are not free of complications which vary from acute retraction, and malfunction to delayed stoma prolapse. Prolapse is an annoying complication that may lead to exco…
View article: Impact of Novel Corona Virus: A Study on Indian Economy
Impact of Novel Corona Virus: A Study on Indian Economy Open
The outbreak of Novel Corona Virus (COVID 19), the new pandemic, has slowed down economic activity all over the world and put most of the economies of the world in front of another recession. The current pandemic situation evolved in Wuhan…
View article: A Novel Bioimpedance-Based Detection of Miltefosine Susceptibility Among Clinical Leishmania donovani Isolates of the Indian Subcontinent Exhibiting Resistance to Multiple Drugs
A Novel Bioimpedance-Based Detection of Miltefosine Susceptibility Among Clinical Leishmania donovani Isolates of the Indian Subcontinent Exhibiting Resistance to Multiple Drugs Open
The extent of susceptibility towards miltefosine (Mil), amphotericin B (AmpB), and paromomycin (Paro) was measured among 19 clinical isolates of Leishmania donovani (LD). Thirteen of these clinical isolates were reported to exhibit low sus…
View article: Substrate Dependent Synergistic Many-Body Effects in Atomically Thin Two Dimensional WS$_2$
Substrate Dependent Synergistic Many-Body Effects in Atomically Thin Two Dimensional WS$_2$ Open
Mott transition has been realized in atomically thin monolayer (ML) of two dimensional semiconductors (WS$_2$) via optically excited carriers above a critical carrier density through many body interactions. The above nonlinear optical tran…
View article: Deregulated molecular genetic pathways in urinary bladder cancer with the importance of molecular biomarkers in diagnosis and follow-up- A comprehensive and updated review
Deregulated molecular genetic pathways in urinary bladder cancer with the importance of molecular biomarkers in diagnosis and follow-up- A comprehensive and updated review Open
This article reviews and compares various currently available non-invasive, molecular biomarker-based tests for bladder cancer (BC) detection, and evaluates other potential molecules that may be used for BC diagnosis and surveillance. Curr…
View article: Fuzzy Logic Controller Design for Voltage, Frequency, Current and Power Control of Three-phase Distributed Generation Based Islanded Microgrid
Fuzzy Logic Controller Design for Voltage, Frequency, Current and Power Control of Three-phase Distributed Generation Based Islanded Microgrid Open
Сьогоднішні екологічно чисті технології, пов'язані з мікромережами, наближаються до розумної системи наномереж. Вона задовольняє попит на електроенергію у всьому світі шляхом належного використання відновлюваних джерел енергії та систем на…
View article: Impact of Thickness and Substrate on Optical Properties of Zno Thin Films
Impact of Thickness and Substrate on Optical Properties of Zno Thin Films Open
During the last decades, ZnO has emerged as the most promising material in optoelectronic and optical applications in the visible region as well as in the infrared and UV region. It is because of the broad direct band gap of 3.37 eV at amb…