Sun Ha Jee
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View article: Sex- and Ethnic-Specific Associations of Serum Lipids with Risk of 12 Cancers: Findings from 506,381 Adults in Two Large Cohorts
Sex- and Ethnic-Specific Associations of Serum Lipids with Risk of 12 Cancers: Findings from 506,381 Adults in Two Large Cohorts Open
The contribution of serum lipids to carcinogenesis, including their effects on inflammation and oxidative stress, remains debated due to inconsistent evidence across populations. This study aimed to elucidate sex- and ethnic-specific assoc…
View article: Adiponectin as a Predictor of Metabolic Dysfunction-Associated Steatotic Liver Disease and Non-Alcoholic Fatty Liver Disease: A 17-Year Korean Cohort Study
Adiponectin as a Predictor of Metabolic Dysfunction-Associated Steatotic Liver Disease and Non-Alcoholic Fatty Liver Disease: A 17-Year Korean Cohort Study Open
Different adiponectin levels revealed distinct risks. This study emphasizes adiponectin's potential as a predictive indicator of MASLD and NAFLD, stressing the need for further investigation across diverse demographic groups.
View article: Biomarkers for non-small cell lung cancer risk using multi-omics approaches: a nested case-control study
Biomarkers for non-small cell lung cancer risk using multi-omics approaches: a nested case-control study Open
The meaningful biomarkers revealed in the current research could be used to enhance the predictive ability for NSCLC risk. Furthermore, we suggest that the protective role of dietary vegetables against NSCLC may be attenuated or absent in …
View article: Cohort profile update: the Korean Cancer Prevention Study-II (KCPS-II) biobank
Cohort profile update: the Korean Cancer Prevention Study-II (KCPS-II) biobank Open
Chronic diseases such as cancer and cardiovascular disease have a substantial impact on mortality and global disease burden. The Korean Cancer Prevention Study-II (KCPS-II) biobank was established to investigate these chronic diseases, wit…
View article: Bilirubin Metabolism and Thyroid Cancer: Insights from ALBI and PALBI Indices
Bilirubin Metabolism and Thyroid Cancer: Insights from ALBI and PALBI Indices Open
Background: This study evaluated the association between bilirubin subtypes (total, indirect, and direct bilirubin) and thyroid cancer risk, with a particular focus on stratified analyses using the ALBI (Albumin-Bilirubin) and PALBI (Plate…
View article: Alcohol consumption and cancer risk in South Korea and the UK: prospective cohort studies
Alcohol consumption and cancer risk in South Korea and the UK: prospective cohort studies Open
Background This study aimed to compare cancer incidence rates between South Korea and the UK, and assess the associated cancer risks due to alcohol consumption. Methods Data were pooled from the Korean Cancer Prevention Study-II and the Ko…
View article: Sex-Specific Associations of Total Bilirubin, ALBI, and PALBI with Lung Cancer Risk: Interactions with Smoking and Alcohol
Sex-Specific Associations of Total Bilirubin, ALBI, and PALBI with Lung Cancer Risk: Interactions with Smoking and Alcohol Open
Background: Bilirubin is a potent endogenous antioxidant that plays a key role in regulating oxidative stress and inflammation, both closely linked to lung carcinogenesis. This study reinterprets the ALBI (Albumin–Bilirubin) and PALBI (Pla…
View article: Discrepancy between Genetically Predicted and Observed Alcohol Intake and Its Impact on Gastric Cancer Susceptibility
Discrepancy between Genetically Predicted and Observed Alcohol Intake and Its Impact on Gastric Cancer Susceptibility Open
Korean drinkers with higher PRS-GC who consume alcohol more than genetically predicted levels are susceptible to GC. PRS-GC and PRS-Alcohol may be beneficial for assessing the impact of alcohol consumption on GC risk in Koreans.
View article: Cohort profile: the Korean National Health Examination Baseline (KNHEB) cohort for longitudinal health monitoring in South Korea
Cohort profile: the Korean National Health Examination Baseline (KNHEB) cohort for longitudinal health monitoring in South Korea Open
Background The Korean National Health Examination Baseline (KNHEB) cohort was established in 2019 by the Korea Disease Control and Prevention Agency and the National Health Insurance Service to address research gaps and improve standardize…
View article: Association Between Creatinine and Lung Cancer Risk in Men Smokers: A Comparative Analysis with Antioxidant Biomarkers from the KCPS-II Cohort
Association Between Creatinine and Lung Cancer Risk in Men Smokers: A Comparative Analysis with Antioxidant Biomarkers from the KCPS-II Cohort Open
Bilirubin, albumin, and uric acid are established endogenous antioxidant biomarkers, whereas the antioxidant role of creatinine has not yet been fully clarified. As a byproduct of creatine metabolism, creatinine may reflect underlying meta…
View article: Supplementary Figure S7 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S7 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Thyroid cancer in KCPS-II The figure is a Manhattan plot for thyroid cancer using KCPS-II data, showing a polygenic pattern.
View article: Supplementary Table S4 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Table S4 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Mendelian randomization results of the association Telomere length (SCHS East Asian individuals) with Lung cancer SEER stage (KoGES)
View article: Supplementary Figure S19 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S19 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Prostate cancer in KCPS-II The figure is a Manhattan plot for prostate cancer using BBJ data, showing a polygenic pattern.
View article: Supplementary Figure S9 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S9 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Bladder cancer in KCPS-II The figure is a Manhattan plot for bladder cancer using KCPS-II data, showing that there are not many significant signals
View article: Supplementary Table 6 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Table 6 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
List of 11 Telomere-Related SNPs Used in the Final Analysis
View article: Supplementary Figure S16 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S16 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Oral cancer in KCPS-II The figure is a Manhattan plot for oral cancer using KCPS_II data, showing significant signals on chromosomes 6.
View article: Supplementary Figure S25 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S25 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Esophageal cancer in BBJ The figure is a Manhattan plot for esophageal cancer using BBJ data, showing significant signals on chromosomes 4 and 12.
View article: Supplementary Table S2 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Table S2 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Mendelian randomization results of the association Telomere length (SCHS East Asian individuals) with Lung cancer subtype (KoGES)
View article: Supplementary Figure S5 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S5 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Total cancer in KCPS-II The figure is a Manhattan plot for total cancer using KCPS-II data, showing a polygenic pattern
View article: Supplementary Figure S26 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S26 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Stomach cancer in BBJ The figure is a Manhattan plot for stomach cancer using BBJ data, showing a polygenic pattern
View article: Supplementary Figure S2 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S2 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Site specific cancer associated with genetically determined telomere length The figure presents the two-sample MR results for each cancer type across three biobanks. It appears that both positive and negative associations coexist depending…
View article: Supplementary Figure S3 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S3 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Comparison of results on telomere length and lung cancer risk using different MR methods in KCPS-II The figure presents the two-sample MR results for telomere length according to lung cancer subtypes.
View article: Supplementary Table S3 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Table S3 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Mendelian randomization results of the association Telomere length (SCHS East Asian individuals) with Lung cancer SEER stage (KCPS-II)
View article: Supplementary Figure S27 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S27 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Liver cancer in BBJ The figure is a Manhattan plot for liver cancer using BBJ data, showing a polygenic pattern.
View article: Supplementary Figure S6 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S6 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Lung cancer in KCPS-II The figure is a Manhattan plot for lung cancer using KCPS-II data, showing that there are not many significant signals.
View article: Supplementary Figure S23 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S23 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Cervical cancer in BBJ The figure is a Manhattan plot for cervical cancer using BBJ data, showing significant signals on chromosomes 6.
View article: Supplementary Figure S14 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization
Supplementary Figure S14 from The Causal Relationship between Telomere Length and Cancer Risk: A Two-Sample Mendelian Randomization Open
Manhattan plot of the GWAS of Laryngeal cancer in KCPS-II The figure is a Manhattan plot for laryngeal cancer using KCPS-II data, showing that there are not many significant signals.