Jung‐Sun Kim
YOU?
Author Swipe
View article: Prognostic value of mayo 2012 vs. european‑modified mayo 2004 staging in AL amyloidosis patients with discordant stage classifications
Prognostic value of mayo 2012 vs. european‑modified mayo 2004 staging in AL amyloidosis patients with discordant stage classifications Open
Background: Systemic AL amyloidosis is a clonal plasma cell disorder characterized by the deposition of misfolded immunoglobulin light chains in vital organs, leading to progressive organ dysfunction. Accurate risk stratification at diagno…
View article: Unveiling the clinical impact of plasma-only mutations in non-small cell lung cancer: a Korean multicenter experience
Unveiling the clinical impact of plasma-only mutations in non-small cell lung cancer: a Korean multicenter experience Open
View article: Integrative Multi-Omics Profiling Identifies Infiltrative HCC as an Immunotherapy-Resistant Subtype with Distinct Molecular Features
Integrative Multi-Omics Profiling Identifies Infiltrative HCC as an Immunotherapy-Resistant Subtype with Distinct Molecular Features Open
Infiltrative HCC is a clinically aggressive and molecularly distinct subtype of advanced HCC. Morphological classification and type IV infiltrative signatures may guide risk stratification and therapeutic decision-making in advanced HCC tr…
View article: Development of a clinical risk scoring system for artesunate treatment failure prediction in malaria patients
Development of a clinical risk scoring system for artesunate treatment failure prediction in malaria patients Open
Parasitemia >5 %, impaired consciousness, and female sex were predictive of artesunate treatment failure as defined by WHO clinical criteria. The developed risk scoring system provides a practical tool for identifying high-risk patients re…
View article: Association of Ezetimibe and Statin Combinations With Recurrent Ischemic Stroke: A Nationwide Study With Dual Design
Association of Ezetimibe and Statin Combinations With Recurrent Ischemic Stroke: A Nationwide Study With Dual Design Open
Background Statin is recommended for patients with ischemic stroke (IS) to lower low‐density lipoprotein cholesterol. Although combining statin with ezetimibe further reduced low‐density lipoprotein cholesterol, its impact on IS recurrence…
View article: Prognostic implication of venoarterial extracorporeal membrane oxygenation in acute myocardial infarction-related cardiogenic shock
Prognostic implication of venoarterial extracorporeal membrane oxygenation in acute myocardial infarction-related cardiogenic shock Open
Background Given the conflicting results regarding the clinical outcomes of venoarterial extracorporeal membrane oxygenation (VA-ECMO) based on etiology, its benefit for patients with cardiogenic shock (CS) remains controversial. This stud…
View article: 335 | THE IMPACT OF CONSOLIDATION TREATMENT AFTER R‐MVP INDUCTION CHEMOTHERAPY IN PATIENTS WITH PRIMARY DIFFUSE LARGE B‐CELL LYMPHOMA OF THE CNS
335 | THE IMPACT OF CONSOLIDATION TREATMENT AFTER R‐MVP INDUCTION CHEMOTHERAPY IN PATIENTS WITH PRIMARY DIFFUSE LARGE B‐CELL LYMPHOMA OF THE CNS Open
View article: Wood-Based Micro-Biochars in a Cement Mixture
Wood-Based Micro-Biochars in a Cement Mixture Open
Immediate action is required to achieve carbon neutrality within the cement industry. The integration of biochar into cement as a component of reinforced concrete has potential to mitigate carbon emissions in the construction sector by ena…
View article: Prognostic Implication of LDL-C Variability and Its Association with Lipid-Lowering Strategies: Insights from the RACING and LODESTAR Trials
Prognostic Implication of LDL-C Variability and Its Association with Lipid-Lowering Strategies: Insights from the RACING and LODESTAR Trials Open
Compared to high-intensity statin therapy, LDL-C variability was not increased with the moderate-intensity statin plus ezetimibe combination therapy; however, it was increased in the treat-to-target strategy. Even among those treated with …
View article: Ticagrelor Monotherapy <i>vs.</i> Ticagrelor With Aspirin in Bleeding and Cardiovascular Events in Acute Coronary Syndrome Patients According to Renal Function: The Subanalysis From the TICO Trial
Ticagrelor Monotherapy <i>vs.</i> Ticagrelor With Aspirin in Bleeding and Cardiovascular Events in Acute Coronary Syndrome Patients According to Renal Function: The Subanalysis From the TICO Trial Open
Regardless of renal function, ticagrelor monotherapy after 3 months of DAPT resulted in a reduced risk of not only NACE but also major or minor bleeding at 1 year compared with ticagrelor-based 12-month DAPT. Irrespective of renal function…
View article: Comparison of Short-term and Standard Duration Dual Antiplatelet Therapy in Elderly Patients: A Pooled Analysis of Five Korean Randomized Clinical Trials
Comparison of Short-term and Standard Duration Dual Antiplatelet Therapy in Elderly Patients: A Pooled Analysis of Five Korean Randomized Clinical Trials Open
ClinicalTrials.gov Identifier: NCT01145079 (RESET), NCT01308281 (IVUS-XPL), NCT01752894 (DETECT-OCT), NCT02494895 (TICO), NCT02513810 (One-Month-DAPT).
View article: Current Status of Lipid Management and Subsequent Cardiovascular Events After Acute Coronary Syndrome in Korea: Real-World Findings From Observational and Survey Studies
Current Status of Lipid Management and Subsequent Cardiovascular Events After Acute Coronary Syndrome in Korea: Real-World Findings From Observational and Survey Studies Open
View article: Comparison of High-Dose versus Low-Dose Paclitaxel Drug-Coated Balloons for Native Femoropopliteal Artery Disease: An Analysis of the K-VIS ELLA Registry
Comparison of High-Dose versus Low-Dose Paclitaxel Drug-Coated Balloons for Native Femoropopliteal Artery Disease: An Analysis of the K-VIS ELLA Registry Open
In this multicenter cohort study of patients with complex FPA disease, there were no significant differences between high-dose DCB and low-dose DCB with respect to freedom from clinically driven TLR, MALE, or all-cause mortality at 12-mont…
View article: Efficient gene deletion of Integrin alpha 4 in primary mouse CD4 T cells using CRISPR RNA pair-mediated fragmentation
Efficient gene deletion of Integrin alpha 4 in primary mouse CD4 T cells using CRISPR RNA pair-mediated fragmentation Open
The functional specialization of CD4 T lymphocytes into various subtypes, including T H 1 and T FH cells, is crucial for effective immune responses. T FH cells facilitate B cell differentiation within germinal centers, while T H 1 cells ar…
View article: Asia–Pacific Real-World Evolocumab Use, LDL-C Reduction, Physician Goals, and Patient Perceptions: HALES Observational Study
Asia–Pacific Real-World Evolocumab Use, LDL-C Reduction, Physician Goals, and Patient Perceptions: HALES Observational Study Open
Real-world, Asia-Pacific data showed that LDL-C reduction after initiating evolocumab was consistent with that observed in other clinical trials and patient populations. Graphical abstract available for this article.·.
View article: Chloroplast genome sequencing and divergence analysis of 18 Pyrus species: insights into intron length polymorphisms and evolutionary processes
Chloroplast genome sequencing and divergence analysis of 18 Pyrus species: insights into intron length polymorphisms and evolutionary processes Open
Pears constitute an essential temperate crop and are primarily produced through interspecific hybridization owing to self-incompatibility that complicates their breeding history. To address this, we sequenced the complete chloroplast (cp) …
View article: Real-World Data on Left Atrial Appendage Occlusion in Asia
Real-World Data on Left Atrial Appendage Occlusion in Asia Open
[Figure: see text]
View article: Predicting Individual Treatment Effects to Determine Duration of Dual Antiplatelet Therapy After Stent Implantation
Predicting Individual Treatment Effects to Determine Duration of Dual Antiplatelet Therapy After Stent Implantation Open
Background After coronary stent implantation, prolonged dual antiplatelet therapy (DAPT) increases bleeding risk, requiring personalization of DAPT duration. The aim of this study was to develop and validate a machine learning model to pre…
View article: Producing a Double Haploid Population Using Microspore Culture and Phenotypic Analysis in <i>Brassica juncea</i>
Producing a Double Haploid Population Using Microspore Culture and Phenotypic Analysis in <i>Brassica juncea</i> Open
View article: Aspirin Monotherapy vs No Antiplatelet Therapy in Stable Patients With Coronary Stents Undergoing Low-to-Intermediate Risk Noncardiac Surgery
Aspirin Monotherapy vs No Antiplatelet Therapy in Stable Patients With Coronary Stents Undergoing Low-to-Intermediate Risk Noncardiac Surgery Open
Among patients undergoing low-to-intermediate risk noncardiac surgery >1 year after stent implantation primarily with a DES, in the setting of lower-than-expected event rates, we failed to identify a significant difference between perioper…
View article: Widespread Use of Imaging-Guided PCI in Asia
Widespread Use of Imaging-Guided PCI in Asia Open
In recent years, a wealth of clinical data has emerged regarding intravascular imaging involving either intravascular ultrasound or optical coherence tomography. This surge in data has propelled the adoption of intravascular imaging-guided…
View article: Effect of rosuvastatin versus atorvastatin on new-onset diabetes mellitus in patients treated with high-intensity statin therapy for coronary artery disease: a post-hoc analysis from the LODESTAR randomized clinical trial
Effect of rosuvastatin versus atorvastatin on new-onset diabetes mellitus in patients treated with high-intensity statin therapy for coronary artery disease: a post-hoc analysis from the LODESTAR randomized clinical trial Open
Background The impact of rosuvastatin versus atorvastatin on new-onset diabetes mellitus (NODM) among patients treated with high-intensity statin therapy for coronary artery disease (CAD) remains to be clarified. This study aimed to evalua…
View article: Signal Detection of DPP-IV Inhibitors using Spontaneous Adverse Event Reporting System in Korea
Signal Detection of DPP-IV Inhibitors using Spontaneous Adverse Event Reporting System in Korea Open
Background:The purpose of this study was to detect signals of adverse events (AEs) of DPP-IV inhibitors using the KIDs-Korea Adverse Event Reporting System (KAERS) database.Methods: This study was conducted using AEs reported from January …
View article: Association between coenzyme Q 10-related genetic polymorphisms and statin-associated myotoxicity in Korean stroke patients
Association between coenzyme Q 10-related genetic polymorphisms and statin-associated myotoxicity in Korean stroke patients Open
Introduction The purpose of this study is to identify the relationship between coenzyme Q 10 (CoQ10)-related gene polymorphisms and statin-related myotoxicity (SRM). Methods We retrospectively analyzed prospectively collected samples from …
View article: C-67 | Ticagrelor monotherapy in ST-elevation myocardial infarction: An individual patient-level meta-analysis from TICO and T-PASS trials
C-67 | Ticagrelor monotherapy in ST-elevation myocardial infarction: An individual patient-level meta-analysis from TICO and T-PASS trials Open
Patients with ST-elevation myocardial infarction (STEMI) tend to be excluded or under-represented in randomized clinical trials evaluating the effects of potent P2Y12 inhibitor monotherapy after short-term dual antiplatelet therapy (DAPT).…
View article: Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention for acute myocardial infarction with cardiogenic shock
Intravascular ultrasound-guided versus angiography-guided percutaneous coronary intervention for acute myocardial infarction with cardiogenic shock Open
The benefits of intravascular ultrasonography (IVUS)-guided percutaneous coronary intervention (PCI) in the clinical context of cardiogenic shock (CS) complicating acute myocardial infarction are lacking. We aimed to investigate the impact…
View article: Continuous Renal Replacement Therapy and Extracorporeal Membrane Oxygenation in Patients with Cardiogenic Shock: A Multicenter Observational Study: Results from the RESCUE Registry
Continuous Renal Replacement Therapy and Extracorporeal Membrane Oxygenation in Patients with Cardiogenic Shock: A Multicenter Observational Study: Results from the RESCUE Registry Open
Backgrounds: Cardiogenic shock (CS) frequently leads to multiorgan failure, potentially necessitating either continuous renal replacement therapy (CRRT) or extracorporeal membrane oxygenation (ECMO). However, there is a lack of comprehensi…
View article: Distinct characteristics and changes in liver function of patients with HCC treated with Ate/Bev for more than 1 year
Distinct characteristics and changes in liver function of patients with HCC treated with Ate/Bev for more than 1 year Open
Background/Aims: Since 2020, Atezolizumab plus bevacizumab (Ate/Bev) has been the standard first-line therapy for unresectable hepatocellular carcinoma (HCC), but long-term treatment studies are limited. This study evaluated the clinical c…
View article: Comparative effectiveness of moderate-intensity statin with ezetimibe therapy versus high-intensity statin monotherapy in patients with acute coronary syndrome: a nationwide cohort study
Comparative effectiveness of moderate-intensity statin with ezetimibe therapy versus high-intensity statin monotherapy in patients with acute coronary syndrome: a nationwide cohort study Open
View article: Clinical Outcomes After Drug-Coated Balloon Treatment in Popliteal Artery Disease: K-POP Registry 12-Month Results
Clinical Outcomes After Drug-Coated Balloon Treatment in Popliteal Artery Disease: K-POP Registry 12-Month Results Open
ClinicalTrials.gov Identifier: NCT02698345.