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View article: Correction: TyG Index and CBC-derived inflammatory indicators individual and mixed effects on all-cause and cardiovascular disease deaths in patients with CHD
Correction: TyG Index and CBC-derived inflammatory indicators individual and mixed effects on all-cause and cardiovascular disease deaths in patients with CHD Open
[This corrects the article DOI: 10.3389/fcvm.2025.1600097.].
View article: Whole-genome identification and functional analysis of grape bHLH transcription factors: new insights into the regulation of monoterpene biosynthesis
Whole-genome identification and functional analysis of grape bHLH transcription factors: new insights into the regulation of monoterpene biosynthesis Open
Basic/helix-loop-helix (bHLH) transcription factors play critical roles in the regulation of plant secondary metabolism, but the molecular mechanisms involved in monoterpene synthesis by the grape bHLH family have not been systematically r…
View article: The influence of peritumoral edema on the efficacy of radiation therapy in glioblastoma treatment: a retrospective study
The influence of peritumoral edema on the efficacy of radiation therapy in glioblastoma treatment: a retrospective study Open
Background Radiation therapy is a crucial treatment method for glioblastoma (GBM). However, the definition of clinical target volume (CTV) varies across different institution and remains a topic of debate. In this study, we reviewed and an…
View article: TyG index and CBC-derived inflammatory indicators individual and mixed effects on all-cause and cardiovascular disease deaths in patients with CHD
TyG index and CBC-derived inflammatory indicators individual and mixed effects on all-cause and cardiovascular disease deaths in patients with CHD Open
Background and aims Currently, most epidemiological investigations have concentrated on exploring the correlation between a singular indicator and the risk of cardiovascular disease. In clinical practice, a single indicator often fails to …
View article: Hic-5 deficiency attenuates MAFLD by inhibiting neutrophils migration via the CXCL1-CXCR2 axis
Hic-5 deficiency attenuates MAFLD by inhibiting neutrophils migration via the CXCL1-CXCR2 axis Open
The study reveals the role of Hic-5 in regulating neutrophils and indicates that it may be a potential therapeutic target for MAFLD.
View article: High Ratio of Manure Substitution Enhanced Soil Organic Carbon Storage via Increasing Particulate Organic Carbon and Nutrient Availability
High Ratio of Manure Substitution Enhanced Soil Organic Carbon Storage via Increasing Particulate Organic Carbon and Nutrient Availability Open
Replacing partial chemical fertilizers with organic fertilizer can increase organic carbon input, change soil nutrient stoichiometry and microbial metabolism, and then affect soil organic carbon (SOC) storage. A 6-year field experiment was…
View article: Effect of endovascular management and anticoagulation alone on acute deep venous thrombosis in patients with inferior vena cava thrombosis
Effect of endovascular management and anticoagulation alone on acute deep venous thrombosis in patients with inferior vena cava thrombosis Open
This retrospective analysis assesses the effectiveness and safety of pharmacomechanical thrombectomy (PMT) and join CDT (catheter-directed thrombolysis) compared to CDT and with standard anticoagulation therapy for LEDVT (acute lower extre…
View article: Leonurine Attenuates CCl4-Induced Hepatic Fibrosis in Mice via the Hippo-YAP Pathway
Leonurine Attenuates CCl4-Induced Hepatic Fibrosis in Mice via the Hippo-YAP Pathway Open
The findings indicate that Leo may exert a protective effect against liver fibrosis through the inhibition of the Hippo-YAP signaling pathway, underscoring its potential as a therapeutic agent for treating hepatic fibrosis.
View article: The role of ATF3 in precision medicine of brain arteriovenous malformation: based on endothelial cell proliferation
The role of ATF3 in precision medicine of brain arteriovenous malformation: based on endothelial cell proliferation Open
Background Brain arteriovenous malformation (BAVM) is a destructive high-flow vascular abnormality that can lead to various cerebral hemodynamic disorders. The incidence of BAVM has risen significantly in recent years, yet treatment option…
View article: Investigating Dual Character of Atmospheric Ammonia on Particulate NH4NO3: Reducing Evaporation Versus Promoting Formation
Investigating Dual Character of Atmospheric Ammonia on Particulate NH4NO3: Reducing Evaporation Versus Promoting Formation Open
Ammonium nitrate (NH4NO3) is a major constituent of fine particulate matter (PM2.5), playing a critical role in air quality and atmospheric chemistry. However, the dual regulatory role of ammonia (NH3) in both the formation and volatilizat…
View article: Research hotspots and frontier analysis of the novel immune checkpoint Nectin-4
Research hotspots and frontier analysis of the novel immune checkpoint Nectin-4 Open
Nectin-4 has emerged as a pivotal therapeutic target for antibody-drug conjugates (ADCs), particularly in advanced urothelial carcinoma (aUC) research. Although extensive literature has been reported on Nectin-4, it is worth noting that no…
View article: Multi-omics analysis unravels the dynamics of flavor profile in ‘Queen Nina’ berries and the regulatory mechanism underlying volatile esters
Multi-omics analysis unravels the dynamics of flavor profile in ‘Queen Nina’ berries and the regulatory mechanism underlying volatile esters Open
'Queen Nina' is a popular grape variety, but the fruit flavor profile and its evolution and regulatory mechanism remain unclear. The flavor profile of 'Queen Nina' was systematically investigated by analyzing the soluble sugars, organic ac…
View article: Hepatic endoplasmic reticulum-derived nanodiscs for broad-spectrum drug detoxification
Hepatic endoplasmic reticulum-derived nanodiscs for broad-spectrum drug detoxification Open
Drug overdose is a pressing global public health challenge, with current detoxification treatments often lacking the broad-spectrum efficacy needed for emergency applications. Inspired by the unique advantages of cell membrane-derived nano…
View article: Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation
Single-cell RNA sequencing revealed PPARG promoted osteosarcoma progression: based on osteoclast proliferation Open
Background Osteosarcoma (OS) is one of the most common primary malignant bone tumors, primarily originating from mesenchymal tissue. It is notorious for its high invasiveness, high disability rate, high mortality rate, and poor prognosis. …
View article: Biocontrol of gray spot disease on Polygonatum cyrtonema Hua by Bacillus velezensis GX1
Biocontrol of gray spot disease on Polygonatum cyrtonema Hua by Bacillus velezensis GX1 Open
This study evaluated the biocontrol efficacy of Bacillus velezensis GX1 against gray spot disease (Pestalotiopsis xuefengensis) on the horticultural species, Polygonatum cyrtonema Hua. Results indicated that GX1 effectively inhibited P. xu…
View article: Seasonally Dependent Daytime and Nighttime Formation of Oxalic Acid Vapor and Particulate Oxalate in Tropical Coastal and Marine Atmospheres
Seasonally Dependent Daytime and Nighttime Formation of Oxalic Acid Vapor and Particulate Oxalate in Tropical Coastal and Marine Atmospheres Open
Oxalic acid is the most abundant low-molecular-weight dicarboxylic acid in the atmosphere, and it plays a crucial role in the formation of new particles and cloud condensation nuclei. However, most observational studies have focused on par…
View article: RBIS regulates ribosome biogenesis to affect progression in lung adenocarcinoma
RBIS regulates ribosome biogenesis to affect progression in lung adenocarcinoma Open
Collectively, these studies suggested the close involvement of RBIS in the progression of lung adenocarcinoma, providing new insights for targeted therapeutic interventions involving ribosomes.
View article: Sea State Parameter Prediction Based on Residual Cross-Attention
Sea State Parameter Prediction Based on Residual Cross-Attention Open
The combination of onboard estimation and data-driven methods is widely applied for sea state parameter prediction. However, conventional data-driven approaches often exhibit limited adaptability to this task, resulting in suboptimal predi…
View article: Block Coordinate Descent Methods for Structured Nonconvex Optimization with Nonseparable Constraints: Optimality Conditions and Global Convergence
Block Coordinate Descent Methods for Structured Nonconvex Optimization with Nonseparable Constraints: Optimality Conditions and Global Convergence Open
Coordinate descent algorithms are widely used in machine learning and large-scale data analysis due to their strong optimality guarantees and impressive empirical performance in solving non-convex problems. In this work, we introduce Block…
View article: Correction: Aleem et al. Characterization of SOD and GPX Gene Families in the Soybeans in Response to Drought and Salinity Stresses. Antioxidants 2022, 11, 460
Correction: Aleem et al. Characterization of SOD and GPX Gene Families in the Soybeans in Response to Drought and Salinity Stresses. Antioxidants 2022, 11, 460 Open
In the original publication [...]
View article: Role of macrophage polarization in diabetic foot ulcer healing: A bibliometric study
Role of macrophage polarization in diabetic foot ulcer healing: A bibliometric study Open
BACKGROUND Diabetic foot ulcers (DFUs) are a significant contributor to disability and mortality in diabetic patients. Macrophage polarization and functional regulation are promising areas of research and show therapeutic potential in the …
View article: Characterization of shade tolerance gene network in soybean revealed by forward integrated reverse genetic studies
Characterization of shade tolerance gene network in soybean revealed by forward integrated reverse genetic studies Open
Shade tolerance is a key trait for cultivars in inter/relay-cropped soybeans in maize fields. Our previous genome-wide association study (GWAS) results on southern China soybean germplasm revealed that the shade tolerance was conferred by …