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View article: SLC transporters as metalloptotic gatekeepers in tumorigenesis: From molecular mechanisms to clinical potential
SLC transporters as metalloptotic gatekeepers in tumorigenesis: From molecular mechanisms to clinical potential Open
Solute carrier (SLC) transporters exert a crucial effect on metalloptosis in tumors via governing the translocation of ions and amino acids across cellular and organelle membranes. Disruptions in metal ion homeostasis mediated by SLC trans…
View article: 552 | BRUTON'S TYRONSINE KINASE INHIBITORS VERSUS VENETOCLAX IN CHRONIC LYMPHOCYTIC LEUKEMIA AND SMALL LYMPHOCYTIC LYMPHOMA: A RETROSPECTIVE REAL‐WORLD ANALYSIS.
552 | BRUTON'S TYRONSINE KINASE INHIBITORS VERSUS VENETOCLAX IN CHRONIC LYMPHOCYTIC LEUKEMIA AND SMALL LYMPHOCYTIC LYMPHOMA: A RETROSPECTIVE REAL‐WORLD ANALYSIS. Open
View article: Soybean productivity can be enhanced by understanding rhizosphere microbiota: evidence from metagenomics analysis from diverse agroecosystems
Soybean productivity can be enhanced by understanding rhizosphere microbiota: evidence from metagenomics analysis from diverse agroecosystems Open
Background Microbial communities associated with roots play a crucial role in the growth and health of plants and are constantly influenced by plant development and alterations in the soil environment. Despite extensive rhizosphere microbi…
View article: Effectiveness of nulliparous women’s different childbirth positions during the second stage of labor: A systematic review and network meta-analysis
Effectiveness of nulliparous women’s different childbirth positions during the second stage of labor: A systematic review and network meta-analysis Open
View article: Molecular mechanism of crisaborole combined with erythromycin against methicillin-resistant Staphylococcus aureus in vivo and in vitro
Molecular mechanism of crisaborole combined with erythromycin against methicillin-resistant Staphylococcus aureus in vivo and in vitro Open
The widespread presence of methicillin-resistant Staphylococcus aureus (MRSA) severely threatens convenient therapeutic options in the postantibiotic era. The use of combinations of existing drugs at this stage may be a viable strategy for…
View article: Neonicotinoids and their metabolites in vegetables and fruits in Shenzhen: Human exposure and health risks
Neonicotinoids and their metabolites in vegetables and fruits in Shenzhen: Human exposure and health risks Open
Neonicotinoids (NEOs) are widely present in vegetables and fruits, and their metabolic processes result in the presence of metabolites (m-NEOs) in vegetables and fruits as well. The toxicity of m-NEOs to the human body is comparable to or …
View article: Riboflavin photochemical therapy triggered PANoptosis by inducing mitochondrial damage in circulating colorectal cancer cells
Riboflavin photochemical therapy triggered PANoptosis by inducing mitochondrial damage in circulating colorectal cancer cells Open
View article: A Multimodal Model for Predicting Gastric Cancer Risk and Implementing Precision Stratification Management in Populations Post-Gastroscopy Screening
A Multimodal Model for Predicting Gastric Cancer Risk and Implementing Precision Stratification Management in Populations Post-Gastroscopy Screening Open
View article: Hydroxycitric acid reconstructs damaged articular cartilages by modifying the metabolic cascade in chondrogenic cells
Hydroxycitric acid reconstructs damaged articular cartilages by modifying the metabolic cascade in chondrogenic cells Open
HCA demonstrates promise as an osteoarthritis therapy by enhancing chondrogenic differentiation. Its ability to modulate crucial metabolic pathways and facilitate cartilage repair suggests potential for clinical translation, addressing a c…
View article: Three-Year Outcomes of 6-Month Paliperidone Palmitate in Adults With Schizophrenia
Three-Year Outcomes of 6-Month Paliperidone Palmitate in Adults With Schizophrenia Open
Importance Long-acting injectable (LAI) antipsychotics have the potential to improve adherence and symptom control in patients with schizophrenia, promoting long-term recovery. Paliperidone palmitate (PP) once every 6 months is the first a…
View article: Development and validation of a preoperative prediction model for all-cause mortality in patients following abdominal aortic aneurysm repair
Development and validation of a preoperative prediction model for all-cause mortality in patients following abdominal aortic aneurysm repair Open
To the Editor: Abdominal aortic aneurysm (AAA) is a life-threatening vascular disease. Surgical intervention is typically recommended when the maximum AAA diameter reaches a threshold of 5.5 cm for men and 5.0 cm for women, or when an AAA …
View article: N6-methyladenosine-associated genetic variants in NECTIN2 and HPCAL1 are risk factors for abdominal aortic aneurysm
N6-methyladenosine-associated genetic variants in NECTIN2 and HPCAL1 are risk factors for abdominal aortic aneurysm Open
Although N6-methyladenosine (m6A) modification has been implicated in the pathogenesis of abdominal aortic aneurysm (AAA), the relationship between m6A-associated single nucleotide polymorphisms (m6A-SNPs) and AAA remains unknown. This stu…
View article: Morphological changes in perisynaptic astrocytes induced by dopamine neuronal degeneration in the striatum of rats
Morphological changes in perisynaptic astrocytes induced by dopamine neuronal degeneration in the striatum of rats Open
Hence, perisynaptic astrocytes wrapping striatal glutamatergic synapses exhibit substantial morphological and functional alterations following DA neuronal degeneration making them a potential target for therapeutic interventions in PD.
View article: 03.06 Cancer-specific oral microbiotherapy for cancer immunotherapy
03.06 Cancer-specific oral microbiotherapy for cancer immunotherapy Open
Background Immunotherapy with immune checkpoint inhibitors (ICI) has revolutionized cancer treatment for many cancers. However, it is associated with low response rates because many cancers have little immune cell infiltration into tumors …
View article: Oxidative phosphorylation is a pivotal therapeutic target of fibrodysplasia ossificans progressiva
Oxidative phosphorylation is a pivotal therapeutic target of fibrodysplasia ossificans progressiva Open
Heterotopic ossification (HO) is a non-physiological bone formation where soft tissue progenitor cells differentiate into chondrogenic cells. In fibrodysplasia ossificans progressiva (FOP), a rare genetic disease characterized by progressi…
View article: Impact of the gene polymorphisms in the renin-angiotensin system on cardiomyopathy risk: A meta-analysis
Impact of the gene polymorphisms in the renin-angiotensin system on cardiomyopathy risk: A meta-analysis Open
Due to the inconsistent findings from various studies, the role of gene polymorphisms in the renin-angiotensin system in influencing the development of cardiomyopathy remains unclear. In this study, we conducted a systematic review and met…
View article: Errata for <i>J. Oleo Science</i>, Vol.73, No.2, p.187 (2024)
Errata for <i>J. Oleo Science</i>, Vol.73, No.2, p.187 (2024) Open
View article: The Impact of Artificial Intelligence on Recalling in Real-World Clinical Settings: A New Exploration to Reduce Unnecessary Thyroid FNAs
The Impact of Artificial Intelligence on Recalling in Real-World Clinical Settings: A New Exploration to Reduce Unnecessary Thyroid FNAs Open
View article: Earlier Use of Long-Acting Injectable Paliperidone Palmitate Versus Oral Antipsychotics in Patients With Schizophrenia
Earlier Use of Long-Acting Injectable Paliperidone Palmitate Versus Oral Antipsychotics in Patients With Schizophrenia Open
Trial Registration: ClinicalTrials.gov identifiers NCT01157351 (PRIDE), NCT01081769 (PROSIPAL), and NCT02431702 (DREaM).
View article: Potential mechanisms of cancer-associated fibroblasts in therapeutic resistance
Potential mechanisms of cancer-associated fibroblasts in therapeutic resistance Open
Despite continuous improvements in research and new cancer therapeutics, the goal of eradicating cancer remains elusive because of drug resistance. For a long time, drug resistance research has been focused on tumor cells themselves; howev…
View article: Deep Learning–Based Stratification of Gastric Cancer Patients from Hematoxylin and Eosin–Stained Whole Slide Images by Predicting Molecular Features for Immunotherapy Response
Deep Learning–Based Stratification of Gastric Cancer Patients from Hematoxylin and Eosin–Stained Whole Slide Images by Predicting Molecular Features for Immunotherapy Response Open
View article: Alteromonas salexigens sp.nov., isolated from coastal seawater
Alteromonas salexigens sp.nov., isolated from coastal seawater Open
A Gram-negative, aerobic, short rod-shaped bacterium, designated ASW11-19 T , was isolated from a coastal seawater sample of the Yellow Sea, PR China. Strain ASW11-19 T grew optimally at 37°C, 3.0–5.0% (w/v) NaCl and pH 7.5. Phylogenetic a…
View article: Expression characteristics and their functional role of IGFBP gene family in pan-cancer
Expression characteristics and their functional role of IGFBP gene family in pan-cancer Open
View article: Collagen X Is Dispensable for Hypertrophic Differentiation and Endochondral Ossification of Human <scp>iPSC</scp> ‐Derived Chondrocytes
Collagen X Is Dispensable for Hypertrophic Differentiation and Endochondral Ossification of Human <span>iPSC</span> ‐Derived Chondrocytes Open
Collagen X is a non‐fibril collagen produced by hypertrophic chondrocytes and was believed to associate with the calcification process of growth plate cartilage. The homozygous loss of Col10a1 gene in mice, however, demonstrated no remarka…
View article: Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer
Association of mitochondrial homeostasis and dynamic balance with malignant biological behaviors of gastrointestinal cancer Open
View article: Morphological Changes of Perisynaptic Astrocytes Induced by Dopamine Depletion in the Striatum of Rats
Morphological Changes of Perisynaptic Astrocytes Induced by Dopamine Depletion in the Striatum of Rats Open
View article: Additional file 1 of Characterizations of the multi-kingdom gut microbiota in Chinese patients with gouty arthritis
Additional file 1 of Characterizations of the multi-kingdom gut microbiota in Chinese patients with gouty arthritis Open
Additional file 1: Table S1. Comparison of the gut bacteriome between GA patients and healthy controls at the phylum level. Table S2. Comparison of the gut bacteriome between GA patients and healthy controls at the genus level. Table S3. C…
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View article: [Impact of vaginal delivery history on anesthesia management of hysteroscopic surgery under intravenous general anesthesia: a cohort study of 99 patients].
[Impact of vaginal delivery history on anesthesia management of hysteroscopic surgery under intravenous general anesthesia: a cohort study of 99 patients]. Open
A history of vaginal delivery has a significant impact on anesthesia management of patients undergoing hysteroscopic surgery under intravenous general anesthesia without tracheal intubation in terms of hemodynamic changes, anesthetic medic…
View article: Novel Anti-LY6G6D/CD3 T-Cell–Dependent Bispecific Antibody for the Treatment of Colorectal Cancer
Novel Anti-LY6G6D/CD3 T-Cell–Dependent Bispecific Antibody for the Treatment of Colorectal Cancer Open
New therapeutics and combination regimens have led to marked clinical improvements for the treatment of a subset of colorectal cancer. Immune checkpoint inhibitors have shown clinical efficacy in patients with mismatch-repair–deficient or …