Ashish Chandra
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View article: Hands-Free Cursor Control Through Eyeball using Python
Hands-Free Cursor Control Through Eyeball using Python Open
This study proposes a revolutionary Human-Computer Interaction (HCI) technology that allows for computer control using eye movements, with a focus on those with physical limitations. Users with limited mobility frequently find themselves u…
View article: Supplementary Table 2 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 2 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 2. Changes in ssGSEA scores from normal kidney tissue to primary ccRCC tumor in normal-primary pairs.
View article: Supplementary Table 6 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 6 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 6. Differential expression analysis by wGII of genes involved in cGAS-STING pathway.
View article: Supplementary Table 10 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 10 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 10. Antibody and incubation procedure for immunohistochemistry (IHC) of CD3 and CD68.
View article: Supplementary Note 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Note 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Inputting information from previous TRACERx Renal studies
View article: Supplementary Table 9 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 9 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 9. Univariate Cox regression results for progression-free survival in the TRACERx Renal cohort based on the expression of each of 613 HERV/LTR elements.
View article: Figure 3 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Figure 3 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Canonical ccRCC subclonal drivers and aneuploidy burden drive specific changes to the tumor transcriptome. A, Illustration of the procedure to analyze the transcriptional association of a subclonal copy number alteration without the…
View article: Supplementary Table 7 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 7 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 7. TCR clones identified applying miXCR to bulk RNA-Sequencing data across 243 ccRCC and kidney-adjacent normal samples in TRACERx Renal.
View article: Figure 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Figure 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Transcriptional inter- and intratumor heterogeneity is pervasive in TRACERx Renal. A, UMAP visualizing the transcriptional variation across 231 tumor samples (gray points). Samples from patients K390, K243, and K153 are highlighted …
View article: Figure 5 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Figure 5 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Spatial diversity of the TCR repertoire suggests heritable nature of the antigenic source in ccRCC. A, TCR and BCR similarity between pairs of samples across 60 TRACERx Renal patients with at least two regions sampled. Dark purple d…
View article: Figure 2 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Figure 2 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Transcriptional evolution mirrors clonal structure and follows recurrent trends. A, Transcriptional distance between primary tumor samples and other primary tumor samples or adjacent normal kidney samples (12 patients with both avai…
View article: Supplementary Table 3 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 3 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 3. Changes in ssGSEA scores from primary to metastasis in primary-metastasis pairs.
View article: Figure 6 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Figure 6 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Greater overall HERV expression, strongly associated with VHL loss of function, correlates with longer progression-free survival in ccRCC. A, Distribution in TRACERx Renal (n = 243 samples) of the median expression across 615…
View article: Supplementary Table 4 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 4 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 4. 50 MSigDB hallmark signatures and corresponding categories.
View article: Supplementary Table 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 1 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 1. Variance in gene expression for 16,716 genes passing expression filtering criteria in the TRACERx Renal study
View article: Supplementary Table 8 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 8 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 8. BCR clones identified applying miXCR to bulk RNA-Sequencing data across 243 ccRCC and kidney-adjacent normal samples in TRACERx Renal.
View article: Supplementary Table 5 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 5 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 5. Changes in ssGSEA scores from early to late clones.
View article: Supplementary Note 2 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Note 2 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Evaluation of the potential to reconstruct TCR repertiore from bulk RNA-Sequencing data
View article: Figure 4 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Figure 4 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Heterogeneity of the TME in ccRCC. A, Association of TME cell abundance estimates from consensus TME and evolutionary trajectory of the tumor from which the sample is taken (in 171 primary tumor samples). Comparisons are one against…
View article: Supplementary Table 11 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Table 11 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Supplementary Table 11. Antibody / Opal combinations, dilutions and positions used for 6 biomarker immunofluorescence panel staining. RTU = Ready to Use.
View article: Data from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Data from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Although the key aspects of genetic evolution and their clinical implications in clear-cell renal cell carcinoma (ccRCC) are well documented, how genetic features coevolve with the phenotype and tumor microenvironment (TME) remains elusive…
View article: Supplementary Figures 1-33 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Supplementary Figures 1-33 from Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
All Supplementary Figures are provided in PDF format with the corresponding legend after each figure. Supplementary Figure 1. Genetic and clinical composition of the TRACERx Renal cohort Supplementary Figure 2. Comparison between transcrip…
View article: Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal
Tracking Nongenetic Evolution from Primary to Metastatic ccRCC: TRACERx Renal Open
Although the key aspects of genetic evolution and their clinical implications in clear-cell renal cell carcinoma (ccRCC) are well documented, how genetic features coevolve with the phenotype and tumor microenvironment (TME) remains elusive…
View article: Practical Approach to Reporting Based on the International System for Serous Fluid Cytopathology
Practical Approach to Reporting Based on the International System for Serous Fluid Cytopathology Open
The International System for Serous Fluid Cytopathology (TIS) is intended for reporting cytological specimens from serous cavities: pleural, abdominal and pericardial cavities. TIS is being adopted into practice in cytology laboratories wo…
View article: Updates in head and neck cytopathology: Insights from European Congress of Pathology Short Course
Updates in head and neck cytopathology: Insights from European Congress of Pathology Short Course Open
Cytological specimens play a pivotal role in head and neck nodule/mass work up and diagnoses. The specimens´ importance has grown with the onset of personalized medicine and the routine use of molecular markers in the diagnostic work up. T…
View article: The International System for Reporting Serous Fluid Cytopathology—An Updated Review
The International System for Reporting Serous Fluid Cytopathology—An Updated Review Open
The International System (TIS) for reporting serous fluid cytopathology was published in December 2020 as a joint project by the International Academy of Cytology and the American Society of Cytopathology. The purpose was to standardize th…
View article: Review of the impact of the International System for Serous Fluid Cytopathology
Review of the impact of the International System for Serous Fluid Cytopathology Open
The International System for Reporting Serous Fluid Cytology (TIS) has been proposed by an expert working team composed of the International Academy of Cytology and the American Society of Cytopathology, following an international survey. …
View article: A brief review of the WHO reporting system for lung cytopathology
A brief review of the WHO reporting system for lung cytopathology Open
The International Academy of Cytology has joined with the International Agency for Research on Cancer to bring together a group of experts in lung cytopathology to develop a WHO Reporting System for Lung Cytopathology (WHO System). This Sy…
View article: The international system for reporting serous fluid cytopathology: The initial project survey
The international system for reporting serous fluid cytopathology: The initial project survey Open
Objective An international panel in the field of body fluid cytology, supported by the International Academy of Cytology and the American Society of Cytopathology, conducted a survey to identify opinions and explore existing practice patte…
View article: Pancreatolithiasis: a case report
Pancreatolithiasis: a case report Open
Introduction: Pancreatolithiasis is a rare medical condition and, most of the time, is a sequelae of chronic pancreatitis. The most common etiology is alcoholism and smoking. While its pathogenesis is not yet clear, two hypotheses explain …