Explanipedia

SYNTHETIC CONTRACEPTIVES AND THEIR IMPACT ON ENDOMETRIAL THICKNESS AND MENSTRUAL CYCLE REGULATION IN REPRODUCTIVE-AGE WOMEN Open

Saqib Zaheer, Rizwan Ahmed, Poshmal Zahid, Shingraf waseem, Sundus Khalid · 2024

The trial investigated the influence of various synthetic contraceptives on endometrial thickness and menstrual cycle regulation in reproductive-age women using a randomized, double-blind, placebo-controlled design. A total of 150 particip…

ASSOCIATION OF NEPHRIN LEVELS WITH CHRONIC KIDNEY DISEASE IN PATIENTS WITH HYPERTENSION Open

Sundus Khalid, Poshmal Zahid, Sheza Waseem, Saqib Zaheer, Rizwan Ahmed · 2024

Chronic Kidney Disease (CKD), a progressive condition often triggered by poorly managed hypertension, can lead to end-stage renal disease (ESRD) if not identified and treated early. This study aims to explore the role of nephrin as a param…

PERCEPTIONS OF MEDICAL ETHICS AND PROFESSIONALISM AMONG PRACTICING PHYSICIANS OF AZAD JAMMU AND KASHMIR: A MIX-METHOD STUDY OF ETHICAL DILEMMAS Open

Shingraf waseem, Sundus Khalid, Saqib Zaheer, Rizwan Ahmed, Poshmal Zahid , et al. · 2024

Background: The evolving nature of clinical practice, patient interactions, and advancements in medical technology may influence how practicing physicians perceive and apply medical ethics and professionalism. Aim: Therefore, this study as…

EFFECTS OF CLOMIPHENE CITRATE DOSAGE AND EXERCISE MODALITY ON SPERM QUALITY IN HYPO-GONADAL MEN Open

Poshmal Zahid, Sheza Waseem, Sundus Khalid, Saqib Zaheer, Rizwan Ahmed · 2024

Hypogonadism in men is a clinical condition characterized by insufficient production of testosterone leading to infertility.The aim of this study is to investigate the combined effects of varying clomiphene citrate (CC) dosages and differe…

What interventions should we implement in England's mental health services? The mental health implementation network (MHIN) mixed-methods approach to rapid prioritisation Open

Shalini Ahuja, Lawrence D. Phillips, Caroline Smartt, Sundus Khalid, Tina Coldham , et al. · 2023

Introduction Setting mental health priorities helps researchers, policy makers, and service funders improve mental health services. In the context of a national mental health implementation programme in England, this study aims to identify…

Physiologically Based Pharmacokinetic Model To Predict Metoprolol Disposition in Healthy and Disease Populations Open

Ammara Zamir, Muhammad Fawad Rasool, Imran Imran, Hamid Saeed, Sundus Khalid , et al. · 2023

The evolution in the development of drugs has increased the popularity of physiologically based pharmacokinetic (PBPK) models. This study seeks to assess the PK of metoprolol in populations with healthy, chronic kidney disease (CKD), and a…

Application of a physiologically based pharmacokinetic model in predicting captopril disposition in children with chronic kidney disease Open

Sundus Khalid, Muhammad Fawad Rasool, Imran Masood, Imran Imran, Hamid Saeed , et al. · 2023

Self-evaluation and depression in adolescents with a chronic illness: A systematic review Open

Emily Hards, Faith Orchard, Sundus Khalid, C. D'Souza, Flora Cohen , et al. · 2022

Objective To conduct a systematic review to establish what is known about the relationship between depression and self-evaluation in adolescents with a chronic illness. Methods A systematic search was conducted using MEDLINE, EMBASE, PsycI…

A Physiologically Based Pharmacokinetic Model for Predicting Diazepam Pharmacokinetics after Intravenous, Oral, Intranasal, and Rectal Applications Open

Sundus Khalid, Muhammad Fawad Rasool, Imran Imran, Abdul Majeed, Hamid Saeed , et al. · 2021

Diazepam is one of the most prescribed anxiolytic and anticonvulsant that is administered through intravenous (IV), oral, intramuscular, intranasal, and rectal routes. To facilitate the clinical use of diazepam, there is a need to develop …

Development and evaluation of physiologically based pharmacokinetic drug-disease models for predicting captopril pharmacokinetics in chronic diseases Open

Muhammad Fawad Rasool, Shazia Ali, Sundus Khalid, Ramsha Khalid, Abdul Majeed , et al. · 2021

Effect of 4 weeks daily wild blueberry supplementation on symptoms of depression in adolescents Open

J. Fisk, Sundus Khalid, Shirley Reynolds, Claire Williams · 2020

Adolescence is an important period for cognitive maturation and emotional regulation, and this age group is particularly vulnerable to developing depression. Diets rich in fruits and vegetables have been associated with decreased risk of d…

Development and Evaluation of Physiologically Based Pharmacokinetic Drug–Disease Models for Predicting Rifampicin Exposure in Tuberculosis and Cirrhosis Populations Open

Muhammad Fawad Rasool, Sundus Khalid, Abdul Majeed, Hamid Saeed, Imran Imran , et al. · 2019

The physiologically based pharmacokinetic (PBPK) approach facilitates the construction of novel drug–disease models by allowing incorporation of relevant pathophysiological changes. The aim of the present work was to explore and identify t…

Effects of Acute Blueberry Flavonoids on Mood in Children and Young Adults Open

Sundus Khalid, Katie L. Barfoot, Gabrielle May, Daniel J. Lamport, Shirley Reynolds , et al. · 2017

Epidemiological evidence suggests that consumption of flavonoids (usually via fruits and vegetables) is associated with decreased risk of developing depression. One plausible explanation for this association is the well-documented benefici…

Is there an association between diet and depression in children and adolescents? A systematic review Open

Sundus Khalid, Claire Williams, Shirley Reynolds · 2016

This review critically evaluates previous studies investigating the association between dietary intake of children and young people and depression and related mental health problems. A systematic literature search was conducted using elect…

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