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View article: Role of the tendon circadian clock in tendinopathy and implications for therapeutics
Role of the tendon circadian clock in tendinopathy and implications for therapeutics Open
Tendinopathy or tendon overuse injury is a major clinical problem for individuals and has a significant socio‐economic cost. Its pathophysiology is not yet fully understood and involves multiple factors, including mechanical, cellular and …
View article: Ratio of early transmitral inflow velocity to early diastolic strain rate predicts atrial fibrillation following acute myocardial infarction
Ratio of early transmitral inflow velocity to early diastolic strain rate predicts atrial fibrillation following acute myocardial infarction Open
The ratio of early transmitral filling velocity to early diastolic strain rate (E/SRe) has been proposed as a new non-invasive measurement of left ventricular filling pressure. We aimed to investigate the ability of E/SRe to predict atrial…
View article: Association between cardiac time intervals and incident heart failure after acute coronary syndrome
Association between cardiac time intervals and incident heart failure after acute coronary syndrome Open
Background Cardiac time intervals are sensitive markers of myocardial dysfunction that predisposes to heart failure (HF). Color tissue Doppler imaging (TDI) curved M-mode is a reliable method for measuring cardiac time intervals. Purpose W…
View article: Left atrial functional measurements’ utility in predicting long‐term risk of atrial fibrillation after isolated CABG
Left atrial functional measurements’ utility in predicting long‐term risk of atrial fibrillation after isolated CABG Open
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia following coronary artery bypass grafting (CABG). We hypothesized that measures of left atrial (LA) function would be useful in predicting AF in patients undergoing …
View article: Left atrial reservoir strain predicts ischaemic stroke after coronary artery bypass grafting independent of postoperative atrial fibrillation
Left atrial reservoir strain predicts ischaemic stroke after coronary artery bypass grafting independent of postoperative atrial fibrillation Open
Aims Measures of left atrial (LA) function are known to predict both ischaemic stroke and atrial fibrillation in specific patient groups. The aim of this study was to investigate the value of LA reservoir strain for predicting ischaemic st…
View article: Early diastolic strain rate in relation to long term prognosis following isolated coronary artery bypass grafting
Early diastolic strain rate in relation to long term prognosis following isolated coronary artery bypass grafting Open
Following CABG, preoperative E/e'sr is an independent predictor of all-cause mortality, especially in patients with preserved systolic function and superior to E/e'.
View article: Prognostic value of layer-specific global longitudinal strain in patients undergoing coronary artery bypass grafting
Prognostic value of layer-specific global longitudinal strain in patients undergoing coronary artery bypass grafting Open
Background Recent improvements in speckle tracking echocardiography have made sectionalized quantification of layer-specific global longitudinal strain (GLS) possible. Prior studies have reported prognostic value of GLS in several cardiac …
View article: Prognostic utility of early systolic lengthening by speckle tracking in patients undergoing coronary artery bypass graft
Prognostic utility of early systolic lengthening by speckle tracking in patients undergoing coronary artery bypass graft Open
Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): The Independent Research Fund Denmark Background Early systolic lengthening (ESL), a paradoxical stretch of myocardial fibers…
View article: Left ventricular end-diastolic pressure is associated with left atrial functional measures by echocardiography
Left ventricular end-diastolic pressure is associated with left atrial functional measures by echocardiography Open
Funding Acknowledgements Type of funding sources: Foundation. Main funding source(s): The Danish Heart Foundation Background Assessment of maximal LA volume (LAVmax) is recommended in imaging guidelines but evidence suggests additional val…
View article: Temporal Release of High-Sensitivity Cardiac Troponin T and I and Copeptin After Brief Induced Coronary Artery Balloon Occlusion in Humans
Temporal Release of High-Sensitivity Cardiac Troponin T and I and Copeptin After Brief Induced Coronary Artery Balloon Occlusion in Humans Open
Background: Cardiac troponins (cTns) are the cornerstone of diagnosing acute myocardial infarction. There is limited knowledge on the duration of ischemia necessary to induce a measurable release of cTns or the very-early-release kinetics …
View article: Echocardiographic Predictors of Mortality in Women With Heart Failure With Reduced Ejection Fraction
Echocardiographic Predictors of Mortality in Women With Heart Failure With Reduced Ejection Fraction Open
Background: Previous studies found that global longitudinal strain is a superior predictor of mortality in male patients with heart failure with reduced ejection fraction (EF). This does not apply to women. Our aim was to investigate sex-s…
View article: 5012Layer specific global longitudinal strain obtained by speckle tracking echocardiography for predicting heart failure and cardiovascular death following STEMI treated with primary PCI
5012Layer specific global longitudinal strain obtained by speckle tracking echocardiography for predicting heart failure and cardiovascular death following STEMI treated with primary PCI Open
Deformation imaging and outcome 1049ence of PSS in the posterior wall was the strongest predictor of both the primary endpoint p=0.006) and all-cause mortality (HR 2.93 95% CI 1.41-6.05,p=0.004).Conclusion: Presence of PSS in the general p…
View article: Insulin‐Like Growth Factor Binding Protein 4 Fragments Provide Incremental Prognostic Information on Cardiovascular Events in Patients With ST‐Segment Elevation Myocardial Infarction
Insulin‐Like Growth Factor Binding Protein 4 Fragments Provide Incremental Prognostic Information on Cardiovascular Events in Patients With ST‐Segment Elevation Myocardial Infarction Open
Background Fragments of insulin‐like growth factor binding protein 4 ( IGFBP ‐4) are potential new biomarkers for cardiac risk assessment. The fragments are generated on specific cleavage by pregnancy‐associated plasma protein‐A, which exe…
View article: Global longitudinal strain predicts incident atrial fibrillation and stroke occurrence after acute myocardial infarction
Global longitudinal strain predicts incident atrial fibrillation and stroke occurrence after acute myocardial infarction Open
Patients with acute myocardial infarction are at increased risk of developing atrial fibrillation. We aimed to evaluate whether speckle tracking echocardiography improves risk stratification for atrial fibrillation in these patients.The st…
View article: Regional Longitudinal Myocardial Deformation Provides Incremental Prognostic Information in Patients with ST-Segment Elevation Myocardial Infarction
Regional Longitudinal Myocardial Deformation Provides Incremental Prognostic Information in Patients with ST-Segment Elevation Myocardial Infarction Open
Regional longitudinal myocardial deformation measures, regardless if determined by TDI or 2DSE, are superior prognosticators to GLS. In addition, impaired longitudinal deformation in the inferior myocardial segment provides prognostic info…
View article: Long-term outcomes in patients with rheumatologic disorders undergoing percutaneous coronary intervention: a BAsel Stent Kosten-Effektivitäts Trial-PROspective Validation Examination (BASKET-PROVE) sub-study
Long-term outcomes in patients with rheumatologic disorders undergoing percutaneous coronary intervention: a BAsel Stent Kosten-Effektivitäts Trial-PROspective Validation Examination (BASKET-PROVE) sub-study Open
The presence of rheumatologic disorders appears to be independently associated with worse outcome in CAD patients undergoing PCI. This calls for further studies and focus on this high-risk group of patients following PCI.
View article: Plasma Neutrophil Gelatinase-Associated Lipocalin Reflects Both Inflammation and Kidney Function in Patients with Myocardial Infarction
Plasma Neutrophil Gelatinase-Associated Lipocalin Reflects Both Inflammation and Kidney Function in Patients with Myocardial Infarction Open
Background/Aims: Neutrophil gelatinase-associated lipocalin (NGAL) has emerged as a marker for acute kidney injury and cardiovascular outcome. However, the relative importance of inflammation versus kidney function on plasma NGAL levels is…