Se Hwan Hwang
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View article: Role of Xylitol Nasal Irrigation in the Management of Chronic Sinusitis: A Systematic Review and Meta‐Analysis
Role of Xylitol Nasal Irrigation in the Management of Chronic Sinusitis: A Systematic Review and Meta‐Analysis Open
Objectives Xylitol, a low‐permeability sugar alcohol, is recommended for treating chronic rhinosinusitis (CRS) due to its ability to decrease liquid salt concentration at the airway surface. This study investigated the efficacy of xylitol …
View article: Efficacy comparison of combined montelukast-antihistamine and montelukast monotherapy in allergic rhinitis: a meta-analysis of randomized controlled trials
Efficacy comparison of combined montelukast-antihistamine and montelukast monotherapy in allergic rhinitis: a meta-analysis of randomized controlled trials Open
Background.Combination therapy with montelukast and oral antihistamines is commonly used in allergic rhinitis (AR), but its comparative benefit over montelukast monotherapy remains unclear. This meta-analysis aimed to evaluate the e…
View article: Clinical Application of Cryotherapy in Intractable Chronic Rhinitis
Clinical Application of Cryotherapy in Intractable Chronic Rhinitis Open
Intranasal cryoablation for chronic rhinitis was first introduced in the 1970s. Initially, the procedure targeted the inferior turbinate and the lower portion of the middle turbinate, the areas rich in vascular sinusoidal tissue and submuc…
View article: Efficacy of Montelukast–Antihistamine Combination Therapy Compared with Antihistamine Monotherapy in Allergic Rhinitis: A Systematic Review and Meta-Analysis
Efficacy of Montelukast–Antihistamine Combination Therapy Compared with Antihistamine Monotherapy in Allergic Rhinitis: A Systematic Review and Meta-Analysis Open
Montelukast-antihistamine combination therapy improves overall symptoms and quality of life compared with antihistamine monotherapy. The magnitude of benefit appears to vary depending on the specific antihistamine used, highlighting the po…
View article: Efficacy and safety of fat graft myringoplasty combined with platelet-rich plasma for managing chronic tympanic membrane perforations: A systemic review and meta-analysis
Efficacy and safety of fat graft myringoplasty combined with platelet-rich plasma for managing chronic tympanic membrane perforations: A systemic review and meta-analysis Open
This study demonstrated a higher success rate and greater hearing improvement with PRP-assisted fat myringoplasty, especially in medium-sized perforations. Both liquid and gel PRP forms were effective, with no significant difference betwee…
View article: Short‐Term Efficacy of Biologics in Recalcitrant Allergic Fungal Rhinosinusitis: A Systematic Review and Meta‐analysis
Short‐Term Efficacy of Biologics in Recalcitrant Allergic Fungal Rhinosinusitis: A Systematic Review and Meta‐analysis Open
Objective Allergic fungal rhinosinusitis (AFRS) is characterized by type I immunoglobulin E (IgE)‐mediated hypersensitivity reactions to fungal antigens. This systematic review and meta‐analysis assessed the efficacy of biologics in the ma…
View article: Efficacy of Additional (Selective) Vidian Neurectomy in Treating Chronic Rhinosinusitis with Nasal Polyp: A Systematic Review and Meta-Analysis
Efficacy of Additional (Selective) Vidian Neurectomy in Treating Chronic Rhinosinusitis with Nasal Polyp: A Systematic Review and Meta-Analysis Open
Introduction: Recently, several reports have been published about the improvement of rhinitis symptoms through posterior nerve ablation. Therefore, we assess the effect of additional (selective) vidian neurectomy in patients with chronic r…
View article: Enhancing Endothelial Differentiation of Mesenchymal Stem Cells Derived from Human Turbinates Using Lab-on-a-Chip Technology
Enhancing Endothelial Differentiation of Mesenchymal Stem Cells Derived from Human Turbinates Using Lab-on-a-Chip Technology Open
Background and Objectives: Endothelial cells are essential to various therapeutic strategies for cardiovascular diseases. Developing efficient methods to generate large quantities of well-defined endothelial cells could improve cardiovascu…
View article: Effectiveness of Septal Swell Body Reduction for Patients With Nasal Airway Obstruction: A Systematic Review and Meta-Analysis
Effectiveness of Septal Swell Body Reduction for Patients With Nasal Airway Obstruction: A Systematic Review and Meta-Analysis Open
Objectives. The septal swell body, a distinct anatomical structure in the anterior nasal septum, is a significant contributor to nasal obstruction and affects airflow dynamics and nasal resistance. This meta-analysis evaluated the impact o…
View article: Efficacy of a Combination Therapy of Montelukast and Antihistamines in Allergic Rhinitis: A Systematic Review and Network Meta-Analysis
Efficacy of a Combination Therapy of Montelukast and Antihistamines in Allergic Rhinitis: A Systematic Review and Network Meta-Analysis Open
Allergic rhinitis (AR) significantly impairs quality of life and often necessitates combination therapies for optimal symptom control. This study aimed to evaluate the efficacy of montelukast-antihistamine combination therapy in patients w…
View article: A Review of the Long-Term Efficacy of Submucosal Medpor Implantation for Empty Nose Syndrome: A Short Communication
A Review of the Long-Term Efficacy of Submucosal Medpor Implantation for Empty Nose Syndrome: A Short Communication Open
To evaluate the long-term effects of submucosal Medpor implants in patients with empty nose syndrome (ENS), using the Sinonasal Outcome Test (SNOT) score as a measure of clinical improvement. A comprehensive search of six databases was con…
View article: Human Nasal Turbinate-Derived Stem Cells for Tissue Engineering and Regenerative Medicine
Human Nasal Turbinate-Derived Stem Cells for Tissue Engineering and Regenerative Medicine Open
Mesenchymal stem cells (MSCs) are multipotent progenitor cells present in adult tissues that are recognized as promising candidates for cell therapy due to their ease of access, straightforward isolation, and capacity for bio-preservation …
View article: The Development of a Human Respiratory Mucosa-on-a-Chip Using Human Turbinate-Derived Mesenchymal Stem Cells
The Development of a Human Respiratory Mucosa-on-a-Chip Using Human Turbinate-Derived Mesenchymal Stem Cells Open
Background and Objectives: This study aimed to investigate the influence of a respiratory mucosa-on-a-chip on the respiratory epithelial differentiation potential of human nasal inferior turbinate-derived stem cells (hNTSCs). Materials and…
View article: Effect of the BiZact™ Low-Temperature Dissecting Device on Intra- and Postoperative Morbidities Related to Tonsillectomy—A Systematic Review and Meta-Analysis
Effect of the BiZact™ Low-Temperature Dissecting Device on Intra- and Postoperative Morbidities Related to Tonsillectomy—A Systematic Review and Meta-Analysis Open
Background and Objectives: We investigated the effects of using a BiZact™ device for tonsillectomy on operating time, intraoperative blood loss, postoperative bleeding rate, and pain through a meta-analysis of the relevant literature. Mate…
View article: Effectiveness of ClariFix (Cryoablation) of the Posterior Nasal Nerve on Nasal Symptoms in Patients With Chronic Rhinitis: A Systematic Review and Meta-Analysis
Effectiveness of ClariFix (Cryoablation) of the Posterior Nasal Nerve on Nasal Symptoms in Patients With Chronic Rhinitis: A Systematic Review and Meta-Analysis Open
Background and Objectives: The present study evaluated the efficacy of cryoablation of the posterior nasal nerve in alleviating symptoms associated with chronic rhinitis.Methods: A systematic review of pertinent literature sourced from Pub…
View article: Perinatal Risk Factors for Asthma and Allergic Rhinitis in Children and Adolescents
Perinatal Risk Factors for Asthma and Allergic Rhinitis in Children and Adolescents Open
Objectives. In this study, we evaluated the associations between birth-related exposures, postnatal factors, and the risk of allergic rhinitis and asthma in children and adolescents.Methods. We performed a comprehensive search of five lite…
View article: Efficacy of Platelet-Rich Plasma in the Treatment of Persistent Olfactory Impairment After COVID-19: A Systematic Review and Meta-Analysis
Efficacy of Platelet-Rich Plasma in the Treatment of Persistent Olfactory Impairment After COVID-19: A Systematic Review and Meta-Analysis Open
Background and Objectives: This study aimed to evaluate the impact of topical platelet-rich plasma (PRP) injection on persistent refractory olfactory dysfunction after COVID-19 infection.Methods: A systematic review was conducted, focusing…
View article: Does Desmopressin Reduce Intraoperative Bleeding in Patients Who Undergo Nasal Surgery? A Systematic Review and Meta-Analysis
Does Desmopressin Reduce Intraoperative Bleeding in Patients Who Undergo Nasal Surgery? A Systematic Review and Meta-Analysis Open
Background and Objectives: This study aimed to determine the efficacy of prophylactic desmopressin administered via the intranasal or intravenous route in reducing intraoperative bleeding during nasal surgery. We conducted a meta-analysis …
View article: Two Cases of Cerebrospinal Fluid Rhinorrhea Repair Surgery Using TachoComb
Two Cases of Cerebrospinal Fluid Rhinorrhea Repair Surgery Using TachoComb Open
Cerebrospinal fluid (CSF) rhinorrhea is a rare condition characterized by the leakage of CSF through the nose. The diagnosis is established through comprehensive history taking, brain imaging, and nasal endoscopy. Surgical intervention is …
View article: Comparison of Liquid-Based Preparations with Conventional Smears in Thyroid Fine-Needle Aspirates: A Systematic Review and Meta-Analysis
Comparison of Liquid-Based Preparations with Conventional Smears in Thyroid Fine-Needle Aspirates: A Systematic Review and Meta-Analysis Open
Background: To compare conventional smears (CSs) and liquid-based preparations (LBPs) for diagnosing thyroid malignant or suspicious lesions. Methods: Studies in the PubMed, SCOPUS, Embase, Web of Science, and Cochrane database published u…
View article: Efficacy of steroid-impregnated spacers after endoscopic sinus surgery in chronic rhinosinusitis: A systematic review and meta-analysis
Efficacy of steroid-impregnated spacers after endoscopic sinus surgery in chronic rhinosinusitis: A systematic review and meta-analysis Open
View article: Surgical safety and effectiveness of bilateral axillo-breast approach robotic thyroidectomy: a systematic review and meta-analysis
Surgical safety and effectiveness of bilateral axillo-breast approach robotic thyroidectomy: a systematic review and meta-analysis Open
View article: Comparative Effectiveness of Cryotherapy and Radiofrequency Ablation for Chronic Rhinitis: A Systematic Review and Meta-analysis
Comparative Effectiveness of Cryotherapy and Radiofrequency Ablation for Chronic Rhinitis: A Systematic Review and Meta-analysis Open
Objectives. Multiple minimally invasive techniques for chronic rhinitis treatment focus on posterior nasal nerve ablation. We conducted a systematic review and meta-analysis to evaluate the efficacy of cryotherapy and radiofrequency ablati…
View article: Characteristics of Human Nasal Turbinate Stem Cells under Hypoxic Conditions
Characteristics of Human Nasal Turbinate Stem Cells under Hypoxic Conditions Open
This study investigated the influence of hypoxic culture conditions on human nasal inferior turbinate-derived stem cells (hNTSCs), a subtype of mesenchymal stem cells (MSCs). It aimed to discern how hypoxia affected hNTSC characteristics, …
View article: Effect of Infraorbital and/or Infratrochlear Nerve Blocks on Postoperative Care in Patients with Septorhinoplasty: A Meta-Analysis
Effect of Infraorbital and/or Infratrochlear Nerve Blocks on Postoperative Care in Patients with Septorhinoplasty: A Meta-Analysis Open
Background and Objectives: Through a comprehensive meta-analysis of the pertinent literature, this study evaluated the utility and efficacy of perioperative infraorbital and/or infratrochlear nerve blocks in reducing postoperative pain and…
View article: Effectiveness of Dupilumab Treatment to Treat Chronic Rhinosinusitis With Nasal Polyposis: A Systematic Review and Meta-Analysis
Effectiveness of Dupilumab Treatment to Treat Chronic Rhinosinusitis With Nasal Polyposis: A Systematic Review and Meta-Analysis Open
Background and Objectives: Evidence bearing on the safety and efficacy of dupilumab treatment for chronic rhinosinusitis with nasal polyps (CRSwNP) has recently been presented by researchers from various institutions. Therefore, we compare…
View article: Desmopressin improves the intraoperative bleeding and surgical field in patients who underwent nasal surgery: Systematic review and meta analysis
Desmopressin improves the intraoperative bleeding and surgical field in patients who underwent nasal surgery: Systematic review and meta analysis Open
Objectives: The aim of our study was to determine the efficacy of prophylactic desmopressin administered via intranasal or intravenous routes in reducing intraoperative bleeding during nasal surgery. We conducted a meta-analysis of relevan…
View article: Effects of Intraoperative Saline-Soaked Pharyngeal Packing on Nausea, Vomiting, and Throat Pain After Nasal Surgery: A Systematic Review and Meta-Analysis
Effects of Intraoperative Saline-Soaked Pharyngeal Packing on Nausea, Vomiting, and Throat Pain After Nasal Surgery: A Systematic Review and Meta-Analysis Open
Background and Objectives: The purpose of this study was to conduct a meta-analysis of the effects of intraoperative pharyngeal packing on postoperative nausea, vomiting, and sore throat in nasal surgery patients.Methods: Databases were se…
View article: A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual Acuity
A Case of IgG4-Related Disease With Sinonasal Involvement Presenting With Decreased Visual Acuity Open
IgG4-related disease (IgG4-RD) is a systemic inflammatory disease characterized by IgG4-positive plasma cell and T lymphocyte infiltration of multiple organs. It commonly involves the pancreas, lacrimal glands, and salivary glands, and it …
View article: The Safety and Efficacy of Dupilumab for Chronic Rhinosinusitis with Nasal Polyposis: A Meta-Analysis
The Safety and Efficacy of Dupilumab for Chronic Rhinosinusitis with Nasal Polyposis: A Meta-Analysis Open