Sung‐Hee Han
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View article: <i>Saccharomyces cerevisiae</i> var. <i>boulardii</i> (HO12) Improves Loperamide-Induced Constipation in Rats <i>via</i> Modulation of Intestinal Neurotransmitters and SCFA Production
<i>Saccharomyces cerevisiae</i> var. <i>boulardii</i> (HO12) Improves Loperamide-Induced Constipation in Rats <i>via</i> Modulation of Intestinal Neurotransmitters and SCFA Production Open
Chronic constipation is a common gastrointestinal disorder characterized by impaired intestinal motility and dysbiosis of the gut microbiota. This study evaluated the therapeutic potential of the probiotic yeast Saccharomyces cerevisiae va…
View article: Effects of Clostridium butyricum on Physiological Parameters and Gut Microbiota in Newborn Hanwoo Calves
Effects of Clostridium butyricum on Physiological Parameters and Gut Microbiota in Newborn Hanwoo Calves Open
A healthy gut microbiota in calves is necessary for optimal performance and development. Considering that probiotics have been shown to improve gut microbiota, the aim of this study was to investigate the effects of Clostridium butyricum o…
View article: Pulsed Field Ablation: A Systematic Review
Pulsed Field Ablation: A Systematic Review Open
Background Atrial fibrillation (AF) is the most prevalent cardiac arrhythmia, leading to significant health and economic burdens. Pulmonary vein isolation (PVI) is a key treatment strategy, with pulsed field ablation (PFA) emerging as a pr…
View article: Early catheter ablation in atrial fibrillation patients recently hospitalized for worsening heart failure
Early catheter ablation in atrial fibrillation patients recently hospitalized for worsening heart failure Open
Background There is still a lack of evidence regarding the benefit of performing atrial fibrillation catheter ablation (AFCA) soon after the hospitalization for worsening heart failure (HF). Objectives To evaluate the effectiveness of AFCA…
View article: Effects of Cr and Al Contents on the Oxide Structures of Ni-Based Superalloys at High Temperatures
Effects of Cr and Al Contents on the Oxide Structures of Ni-Based Superalloys at High Temperatures Open
In this study, the morphology of high-temperature surface oxides in Ni-based superalloys was investigated as a function of Cr and Al content. First, the oxide layer morphologies of various alloys published in the literature were classified…
View article: Anti-fatigue and antioxidative effects of amino acid (Leu, Gln, Cys)-EGCG complex via NRF2 and PGC-1α pathways: insights from cellular, animal, and pilot clinical studies
Anti-fatigue and antioxidative effects of amino acid (Leu, Gln, Cys)-EGCG complex via NRF2 and PGC-1α pathways: insights from cellular, animal, and pilot clinical studies Open
The AA-EGCG mixture enhances mitochondrial biogenesis and antioxidant capacity by activating the NRF2 and PGC-1α pathways, improving physical performance and reducing fatigue. This study highlights its potential as a supplement for managin…
View article: Impact of the probiotic <i>Bacillus coagulans</i> on loperamide-induced delayed bowel movement in Sprague–Dawley rats
Impact of the probiotic <i>Bacillus coagulans</i> on loperamide-induced delayed bowel movement in Sprague–Dawley rats Open
This study investigated the effects of Bacillus coagulans on alleviating loperamide-induced constipation.
View article: Preparation of chitosan oligosaccharides from chitosan of tenebrio molitor and its prebiotic activity
Preparation of chitosan oligosaccharides from chitosan of tenebrio molitor and its prebiotic activity Open
This study aimed to establish the optimal production conditions for mealworm chitosan oligosaccharides (MCOS) using the response surface methodology and measure the prebiotic effect of MCOS prepared on cecal microbiota through in vitro ana…
View article: Lactitol Alleviates Loperamide-Induced Constipation in Sprague Dawley Rats by Regulating Serotonin, Short-Chain Fatty Acids, and Gut Microbiota
Lactitol Alleviates Loperamide-Induced Constipation in Sprague Dawley Rats by Regulating Serotonin, Short-Chain Fatty Acids, and Gut Microbiota Open
The objective of this study was to examine the impact of lactitol on constipation caused by loperamide in Sprague Dawley rats, with a particular emphasis on its underlying mechanisms and potential health advantages. The lactitol effectivel…
View article: Mutation spectrum of <i>NF1</i> gene in Korean unrelated patients with neurofibromatosis 1: Six novel pathogenic variants
Mutation spectrum of <i>NF1</i> gene in Korean unrelated patients with neurofibromatosis 1: Six novel pathogenic variants Open
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View article: Lactobacillus brevis M2-Fermented Whey Protein Hydrolysate Increases Slow-Wave Sleep via GABAA Receptors in Rodent Models
Lactobacillus brevis M2-Fermented Whey Protein Hydrolysate Increases Slow-Wave Sleep via GABAA Receptors in Rodent Models Open
In this study, we investigated the effects of whey protein hydrolysate (WPH) fermented with Lactobacillus brevis on sleep behavior and GABAergic mechanisms in rodent models. Fermentation converted the glutamate in WPH to high (3.15 ± 0.21 …
View article: Yohimbine Inhibits PDGF-Induced Vascular Smooth Muscle Cell Proliferation and Migration via FOXO3a Factor
Yohimbine Inhibits PDGF-Induced Vascular Smooth Muscle Cell Proliferation and Migration via FOXO3a Factor Open
Yohimbine (YHB) has been reported to possess anti-inflammatory, anticancer, and cardiac function-enhancing properties. Additionally, it has been reported to inhibit the proliferation, migration, and neointimal formation of vascular smooth …
View article: Enzyme Activity and Lipogenesis Inhibition by Fermented Grain Using Natural Enzymes
Enzyme Activity and Lipogenesis Inhibition by Fermented Grain Using Natural Enzymes Open
This study aims to compare the effects of three enzyme-rich foods, including one fermented (grain enzyme) and two non-fermented foods (enzyme foods 1 and 2), by investigating their antioxidant, anti-inflammatory, and anti-adipogenic proper…
View article: The Preparation and Physiochemical Characterization of Tenebrio molitor Chitin Using Alcalase
The Preparation and Physiochemical Characterization of Tenebrio molitor Chitin Using Alcalase Open
Chitin is mostly produced from crustaceans, but it is difficult to supply raw materials due to marine pollution, and the commonly used chemical chitin extraction method is not environmentally friendly. Therefore, this study aims to establi…
View article: Protein Hydrolysate from Spirulina platensis Prevents Dexamethasone-Induced Muscle Atrophy via Akt/Foxo3 Signaling in C2C12 Myotubes
Protein Hydrolysate from Spirulina platensis Prevents Dexamethasone-Induced Muscle Atrophy via Akt/Foxo3 Signaling in C2C12 Myotubes Open
Loss of muscle mass is the primary symptom of sarcopenia. Protein intake is recommended to prevent muscle mass loss, and Spirulina platensis, a microalga with high protein content, is a potential protein supplement. Here, we evaluated the …
View article: The Effects of Self-perceived Parenting Attitudes on Visuo-spatial Attention and Mental Rotation Abilities among Adolescents
The Effects of Self-perceived Parenting Attitudes on Visuo-spatial Attention and Mental Rotation Abilities among Adolescents Open
The present study aimed to investigate the effect of adolescents’ perceived negative evaluation of parenting on their visuo-spatial attention and mental rotation abilities. The experimental groups were divided into negatively evaluating gr…
View article: Antioxidant and Immunostimulatory Activities of a Submerged Culture of Cordyceps sinensis Using Spent Coffee
Antioxidant and Immunostimulatory Activities of a Submerged Culture of Cordyceps sinensis Using Spent Coffee Open
Spent coffee grounds (SCG) are inexpensive materials that have been used as a source of antioxidants and polysaccharides with immunostimulatory activity. In this study, we performed a microbial fermentation of SCG using Cordyceps sinensis …
View article: Anti-depressant effects of ethanol extract from <i>Cannabis sativa</i> (hemp) seed in chlorpromazine-induced <i>Drosophila melanogaster</i> depression model
Anti-depressant effects of ethanol extract from <i>Cannabis sativa</i> (hemp) seed in chlorpromazine-induced <i>Drosophila melanogaster</i> depression model Open
Depression is a severe mental illness caused by a deficiency of dopamine and serotonin. Cannabis sativa L. (Cannabaceae) has long been used to treat pain, nausea, and depression. This study investigates the anti-depressant effects of C. sa…
View article: Anti-depressant effects of ethanol extract from <i>Cannabis sativa</i> (hemp) seed in chlorpromazine-induced <i>Drosophila melanogaster</i> depression model
Anti-depressant effects of ethanol extract from <i>Cannabis sativa</i> (hemp) seed in chlorpromazine-induced <i>Drosophila melanogaster</i> depression model Open
Collectively, HE administration alleviates depression-like symptoms by modulating the circadian rhythm-related behaviours, transcript levels of neurotransmitter receptors, and neurotransmitter levels in the CPZ-induced Drosophila model. Ho…
View article: Chemical and biological properties of puffed Dendrobium officinale extracts: Evaluation of antioxidant and anti-fatigue activities
Chemical and biological properties of puffed Dendrobium officinale extracts: Evaluation of antioxidant and anti-fatigue activities Open
Dendrobium officinale (D. officinale, DO) is a traditional medicinal herb used in China. Phytochemicals and its antioxidant activity of puffed dendrobium extract was measured for antioxidant capacity. Physiological mechanism on skeletal mu…
View article: Investigation of Intestinal Microbiota and Fecal Calprotectin in Non-Toxigenic and Toxigenic Clostridioides difficile Colonization and Infection
Investigation of Intestinal Microbiota and Fecal Calprotectin in Non-Toxigenic and Toxigenic Clostridioides difficile Colonization and Infection Open
In this study, we aimed to evaluate the composition of the intestinal microbiota and level of fecal calprotectin in Clostridioides difficile-colonized patients. We included 102 C. difficile non-colonized (group I), 93 C. difficile colonize…
View article: Prevalence of Carbapenem-Resistant Enterobacteriaceae in Seoul, Korea
Prevalence of Carbapenem-Resistant Enterobacteriaceae in Seoul, Korea Open
The prevalence of carbapenem-resistant Enterobacteriaceae (CRE) is increasing globally. However, a few studies have addressed their epidemiology in Seoul, Korea. In this study, we conducted one-year surveillance of CRE among 1,468 clinical…