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View article: Addressing Low Physical Activity in COPD: The Importance of Patients’ Symptom Perception
Addressing Low Physical Activity in COPD: The Importance of Patients’ Symptom Perception Open
The importance of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) is well established, but improving adherence remains a challenge, particularly among patients with low physical activity (PA) despite adequate …
View article: Impact of Low Hand Grip Strength on Quality of Life, Utilization of Healthcare, and Mental Health in Individuals with Airflow Limitation
Impact of Low Hand Grip Strength on Quality of Life, Utilization of Healthcare, and Mental Health in Individuals with Airflow Limitation Open
Overall, low HGS was associated with decreased quality of life and worsening mental health in participants with AFL. Our findings underscore the importance of muscle strength for HRQoL, particularly in those with impaired lung function and…
View article: Impact of the duration of corticosteroid treatment for postoperative acute lung injury following lung cancer surgery
Impact of the duration of corticosteroid treatment for postoperative acute lung injury following lung cancer surgery Open
Short-course corticosteroid treatment was associated with a lower rate of surgical site complications, additional ICU admission, and in-hospital mortality, which suggests the necessity of efforts for reducing the total duration by weighing…
View article: COVID-19 and Long-term Risk of Ischemic Heart Disease in Asthma
COVID-19 and Long-term Risk of Ischemic Heart Disease in Asthma Open
Despite the importance of comorbid ischemic heart disease (IHD) in the prognosis of asthma, the long-term impact of coronavirus disease 2019 (COVID-19) on IHD in adults with asthma remains unclear. This study investigated the long-term eff…
View article: Risk of Stroke in COVID-19 Survivors With Asthma: A Nationwide, Population-Based Cohort Study
Risk of Stroke in COVID-19 Survivors With Asthma: A Nationwide, Population-Based Cohort Study Open
This study highlights a significant association between severe COVID-19 and stroke occurrence in adults with asthma, emphasizing the need for ongoing stroke monitoring to improve long-term asthma outcomes during the COVID-19 endemic period.
View article: Association of moderate-to-vigorous physical activity with reduction of acute exacerbation in COPD patients using a dual ultra-long-acting bronchodilators
Association of moderate-to-vigorous physical activity with reduction of acute exacerbation in COPD patients using a dual ultra-long-acting bronchodilators Open
Inhaler therapy and physical activity (PA) are important methods of chronic obstructive pulmonary disease (COPD) management. This study aimed to investigate the additional benefit of moderate-to-vigorous PA (MVPA) in patients with COPD usi…
View article: Long-term clinical course of <i>Mycobacterium avium</i> complex pulmonary disease patients with treatment failure
Long-term clinical course of <i>Mycobacterium avium</i> complex pulmonary disease patients with treatment failure Open
Despite guideline-based therapy, some patients with Mycobacterium avium complex pulmonary disease (MAC-PD) experience treatment failure. We analyzed the clinical courses of 271 patients with treatment-refractory MAC-PD who discontinued the…
View article: Secondary Immunodeficiency and Non-cystic Fibrosis Bronchiectasis
Secondary Immunodeficiency and Non-cystic Fibrosis Bronchiectasis Open
Bronchiectasis is a chronic respiratory disease characterized by abnormal dilation of the bronchi that causes cough, sputum, and recurrent infections. As it may be associated with various respiratory or systemic diseases, a critical aspect…
View article: Single-cell transcriptomics by clinical course of Mycobacterium avium complex pulmonary disease
Single-cell transcriptomics by clinical course of Mycobacterium avium complex pulmonary disease Open
Mycobacterium avium complex pulmonary disease (MAC-PD) has a heterogeneous clinical course. However, immune profiles associated with MAC-PD clinical course are limited. We performed single-cell RNA sequencing of peripheral blood mononuclea…
View article: <i>In Vitro</i> Activity of Benzimidazole (SPR719) Against Clinical Isolates of Nontuberculous Mycobacteria With and Without Clarithromycin or Amikacin Resistance
<i>In Vitro</i> Activity of Benzimidazole (SPR719) Against Clinical Isolates of Nontuberculous Mycobacteria With and Without Clarithromycin or Amikacin Resistance Open
Limited data are available regarding the in vitro activity of SPR719, a derivative of benzimidazole, against diverse nontuberculous mycobacteria (NTM) species. We investigated the minimum inhibitory concentration (MIC) and minimum bacteric…
View article: Clinical characteristics and outcomes of hypersensitivity pneumonitis in South Korea
Clinical characteristics and outcomes of hypersensitivity pneumonitis in South Korea Open
Hypersensitivity pneumonitis (HP) is an interstitial lung disease (ILD) that results from an immune-mediated reaction involving various antigens in susceptible individuals. However, the clinical characteristics and outcomes of HP in South …
View article: Clinical characteristics and outcomes of hypersensitivity pneumonitis in South Korea
Clinical characteristics and outcomes of hypersensitivity pneumonitis in South Korea Open
Background: Hypersensitivity pneumonitis (HP) is an interstitial lung disease (ILD) that results from an immune-mediated reaction involving various antigens in susceptible individuals. However, the clinical characteristics and outcomes of …
View article: Nondiagnostic, radial‐probe endobronchial ultrasound‐guided biopsy for peripheral lung lesions: The added value of radiomics from ultrasound imaging for predicting malignancy
Nondiagnostic, radial‐probe endobronchial ultrasound‐guided biopsy for peripheral lung lesions: The added value of radiomics from ultrasound imaging for predicting malignancy Open
Objectives This study investigated whether radiomic features extracted from radial‐probe endobronchial ultrasound (radial EBUS) images can assist in decision‐making for subsequent clinical management in cases with indeterminate pathologic …
View article: Antibiotic Maintenance and Redevelopment of Nontuberculous Mycobacteria Pulmonary Disease after Treatment of Mycobacterium avium Complex Pulmonary Disease
Antibiotic Maintenance and Redevelopment of Nontuberculous Mycobacteria Pulmonary Disease after Treatment of Mycobacterium avium Complex Pulmonary Disease Open
Limited data are available regarding the impact of the antibiotic maintenance period on the redevelopment of Mycobacterium avium complex-pulmonary (MAC-PD) disease after microbiological cure. To improve treatment outcomes and reduce the re…
View article: Trends and factors associated with influenza vaccination in subjects with asthma: analysis of the Korea National Health and Nutrition Examination Survey between 2010 and 2019
Trends and factors associated with influenza vaccination in subjects with asthma: analysis of the Korea National Health and Nutrition Examination Survey between 2010 and 2019 Open
Background: Despite the importance of influenza vaccination, its rates in subjects with asthma are suboptimal, especially in the young population. Methods: Among 72,843 adults aged ⩾18 years from the Korea National Health and Nutrition Exa…
View article: Change in individual chronic obstructive pulmonary disease assessment test item scores after short-term bronchodilator therapy and its impact on exacerbation in treatment-naïve patients with chronic obstructive pulmonary disease
Change in individual chronic obstructive pulmonary disease assessment test item scores after short-term bronchodilator therapy and its impact on exacerbation in treatment-naïve patients with chronic obstructive pulmonary disease Open
Background: The chronic obstructive pulmonary disease (COPD) assessment test (CAT) measures the health status of patients with COPD. We aimed to investigate the change in individual CAT scores after short-term bronchodilator therapy among …
View article: Clinical Characteristics of COPD Patients According to COPD Assessment Test (CAT) Score Level: Cross-Sectional Study
Clinical Characteristics of COPD Patients According to COPD Assessment Test (CAT) Score Level: Cross-Sectional Study Open
Purpose: The chronic obstructive pulmonary disease (COPD) assessment test (CAT) is widely used to assess the impact of COPD symptoms on health status. Whilst the CAT consists of eight different items, details on the distribution of each it…
View article: Predicting the Risk of Malignancy of Lung Nodules Diagnosed as Indeterminate on Radial Endobronchial Ultrasound-Guided Biopsy
Predicting the Risk of Malignancy of Lung Nodules Diagnosed as Indeterminate on Radial Endobronchial Ultrasound-Guided Biopsy Open
The next diagnostic step in cases of indeterminate radial probe endobronchial ultrasound (radial EBUS)-guided biopsy results remains uncertain. This study aimed to identify risk factors for malignancy based on clinical findings, chest comp…
View article: Tracheobronchopathia osteochondroplastica (TPO) associated with tracheobronchial amyloidosis (TBA)
Tracheobronchopathia osteochondroplastica (TPO) associated with tracheobronchial amyloidosis (TBA) Open
Tracheobronchopathia osteochondroplastica (TPO) is an idiopathic disease involving the cartilage rings of the large airway, characterized by submucosal calcified nodules. Localized tracheobronchial amyloidosis (TBA) is another rare disease…
View article: S-100-Negative malignant pulmonary granular cell tumor: A case report
S-100-Negative malignant pulmonary granular cell tumor: A case report Open
Malignant pulmonary granular cell tumor (GCT) is extremely rare and difficult to distinguish from benign GCT. Most GCTs are neural-type and express S-100. However, a small subset of tumors sub-classified as the non-neural type do not expre…
View article: Surgically intractable bronchopleural fistula treated with endobronchial valve insertion by isolating the tract with indigo carmine: A case report
Surgically intractable bronchopleural fistula treated with endobronchial valve insertion by isolating the tract with indigo carmine: A case report Open
Bronchopleural fistula (BPF) is a communication between the pleural space and the bronchial tree. Herein, we report a patient with persistent air leak after necrotizing pneumonia, where tract of BPF was not apparent in computed tomography …