Sunil Bhandari
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View article: A Systematic Review Investigates the Safety and Efficacy of Intravenous Iron Dosing in Peritoneal Dialysis
A Systematic Review Investigates the Safety and Efficacy of Intravenous Iron Dosing in Peritoneal Dialysis Open
Aims/Background Anaemia is a common complication in chronic kidney disease, particularly in people with advanced kidney failure, contributing to increased morbidity and mortality. Iron repletion and erythropoietin-stimulating agents are wi…
View article: Investigating the Impact of Ferric Derisomaltose (FDI) on Patient-Reported Quality-of-Life Outcome Measures in Iron-Deficient but Not Anaemic Patients with Chronic Kidney Disease
Investigating the Impact of Ferric Derisomaltose (FDI) on Patient-Reported Quality-of-Life Outcome Measures in Iron-Deficient but Not Anaemic Patients with Chronic Kidney Disease Open
Background/Objectives: Iron deficiency without anaemia (IDNA) is common in non-dialysis-dependent chronic kidney disease (CKD) and contributes to fatigue, reduced exercise tolerance, and impaired quality of life (QoL). While intravenous (I…
View article: Effect of performing daily fetal movement count on maternal-fetal attachment level among low risk primigravida - A randomised controlled trial
Effect of performing daily fetal movement count on maternal-fetal attachment level among low risk primigravida - A randomised controlled trial Open
Background: Maternal-fetal attachment is the bond that grows over time during the pregnancy via several antenatal practices for a healthy fetus. One such practice is daily fetal movement count which may play a vital part in promoting mater…
View article: Hyperkalaemia in CKD and diabetes
Hyperkalaemia in CKD and diabetes Open
Hyperkalaemia, both acute and chronic, limits the ability to optimally manage people with chronic kidney disease, cardiovascular disease and diabetes with renin angiotensin aldosterone system inhibitors. Data demonstrate the benefits of op…
View article: Insights into Menkes Disease: A Case report on Rare X-Linked Copper Metabolism Disorder Linked to ATP7A Mutation
Insights into Menkes Disease: A Case report on Rare X-Linked Copper Metabolism Disorder Linked to ATP7A Mutation Open
Menkes’ disease (MD) is a X-linked recessive degenerative disorder, involving mutations of ATP7A gene, characterized by impaired copper transport at the intracellular level contributes to nervous system dysfunction. Clinical manifestations…
View article: International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensus
International Consortium to Classify Ageing-related Pathologies (ICCARP) senescence definitions: achieving international consensus Open
With the global increase in ageing populations, a clear understanding of the physiological and pathological changes associated with ageing is vital for advancing research and clinical practice. Following the World Health Organization’s dec…
View article: Digital physical activity intervention via the Kidney BEAM platform in patients with polycystic kidney disease: a randomized controlled trial
Digital physical activity intervention via the Kidney BEAM platform in patients with polycystic kidney disease: a randomized controlled trial Open
Background In people living with polycystic kidney disease (PKD), physical inactivity may contribute to poor health-related quality of life (HRQoL). To date, no research has elucidated the impact of a PKD-specific physical activity program…
View article: HBE BETA-THALASSEMIA IS ASSOCIATED WITH IGA NEPHROPATHY
HBE BETA-THALASSEMIA IS ASSOCIATED WITH IGA NEPHROPATHY Open
Thalassemia are a group of autosomal recessive inherited disorders of haemoglobin synthesis where in mutations of the -globin gene lead to various degrees of defective -chain production, an imbalance in -globin chain synthesis, ineffective…
View article: Intravenous iron in chronic kidney disease without anaemia but iron deficiency: A scoping review
Intravenous iron in chronic kidney disease without anaemia but iron deficiency: A scoping review Open
Iron deficiency (ID) is a prevalent complication of chronic kidney disease (CKD), often managed reactively when associated with anaemia. This scoping review evaluates the evidence supporting intravenous (IV) iron therapy in non-anaemic ind…
View article: Iron management and exercise training in individuals with chronic kidney disease: lived experiences
Iron management and exercise training in individuals with chronic kidney disease: lived experiences Open
Background Non-anaemic iron deficiency is highly prevalent in people living with chronic kidney disease (CKD) but is underdiagnosed and undertreated, especially in earlier stages of CKD. A multicentre trial assessing the effect of intraven…
View article: Roxadustat Efficacy and Safety in Patients Receiving Peritoneal Dialysis: Pooled Analysis of Four Phase 3 Studies
Roxadustat Efficacy and Safety in Patients Receiving Peritoneal Dialysis: Pooled Analysis of Four Phase 3 Studies Open
Background/Objectives: Roxadustat is an oral hypoxia-inducible factor prolyl hydroxylase inhibitor approved to treat anemia of chronic kidney disease (CKD). The efficacy and safety of roxadustat compared with parenteral erythropoiesis-stim…
View article: Exploring How the Kidney BEAM Physical Activity Digital Health Intervention Improved Mental Health-Related Quality of Life for People Living With Kidney Disease
Exploring How the Kidney BEAM Physical Activity Digital Health Intervention Improved Mental Health-Related Quality of Life for People Living With Kidney Disease Open
Elements of the Kidney BEAM intervention that contributed to the main quantitative trial findings were identified. This will allow researchers and practitioners to maximize the effectiveness of DHIs to enhance healthy behaviors in people l…
View article: 12450 Beyond the Surface: A Deep Dive into Pancreatic Insulinoma
12450 Beyond the Surface: A Deep Dive into Pancreatic Insulinoma Open
Disclosure: S. Bhandari: None. R. Elhag: None. J. Singh: None. N. Rastogi: None. Background: Pancreatic neuroendocrine tumors (NET) are rare lesions that are typically sporadic, solitary and usually <2cm in diameter, with reported incid…
View article: 9355 Thyroid Storm: In the Aftermath of Thyrotropin Stimulated Scan
9355 Thyroid Storm: In the Aftermath of Thyrotropin Stimulated Scan Open
Disclosure: S. Bhandari: None. I. Jamshed: None. A. Bag: None. N. Rastogi: None. A. Ramsetty: None. Introduction: Cases of thyroid storm have been reported in metastatic follicular thyroid cancer following surgery and radioactive iodine tr…
View article: Defining an Ageing-Related Pathology, Disease or Syndrome: International Consensus Statement
Defining an Ageing-Related Pathology, Disease or Syndrome: International Consensus Statement Open
Background Around the world, individuals are living longer, but an increased average lifespan does not always equate to an increased healthspan. With advancing age, the increased prevalence of ageing-related diseases can have a significant…
View article: Cystatin C vs creatinine eGFR in advanced CKD: an analysis of the STOP-ACEi trial
Cystatin C vs creatinine eGFR in advanced CKD: an analysis of the STOP-ACEi trial Open
Background In this secondary analysis of the STOP-ACEi trial, we explored the impact of discontinuing or continuing renin–angiotensin system inhibitor therapy in people with advanced chronic kidney disease on cystatin C estimated glomerula…
View article: Can Ayurveda medicine supplement modern medical treatments in chronic disease management?
Can Ayurveda medicine supplement modern medical treatments in chronic disease management? Open
The editorial highlights the fact that there is limited communication between healthcare providers and patients about complementary and integrative medicine (TCI) like Ayurveda. To address this, healthcare professionals need better educati…
View article: Cystatin C as a Marker of Kidney Function in Children
Cystatin C as a Marker of Kidney Function in Children Open
This review examines the reliability of cystatin C as a biomarker for kidney function in paediatric populations. Chronic kidney disease (CKD) affects a significant number of children globally, leading to severe health complications such as…
View article: Description and Cross-Sectional Analyses of 25,880 Adults and Children in the UK National Registry of Rare Kidney Diseases Cohort
Description and Cross-Sectional Analyses of 25,880 Adults and Children in the UK National Registry of Rare Kidney Diseases Cohort Open
We observed no evidence of systematic biases in recruitment of patients into RaDaR; however, the data provide empirical evidence of negative economic and social consequences (across all ethnicities) experienced by families with children af…
View article: #686 The impact of Ferric Derisomaltose (FDI) on role physical functioning in iron deficient but not anaemic patients with chronic kidney disease
#686 The impact of Ferric Derisomaltose (FDI) on role physical functioning in iron deficient but not anaemic patients with chronic kidney disease Open
Background and Aims Chronic kidney disease (CKD) is a progressive disorder affecting physiological function, specifically iron deficiency. Iron is crucial for red blood cell production, oxygen transport, mitochondrial function, and cardiac…
View article: WCN24-398 REPORT ON STOP-ACEi TRIAL: REVIEWING CYSTATIN C LEVELS IN CKD PATIENTS
WCN24-398 REPORT ON STOP-ACEi TRIAL: REVIEWING CYSTATIN C LEVELS IN CKD PATIENTS Open
In this pre-specified secondary analysis of the STOP-ACEi trial (1-2), we explored the impact of stopping or continuing renin angiotensin system (RAS) inhibitor therapy in people with advanced CKD on serum cystatin C levels.
View article: The clinical value and cost effectiveness of a 6-month digital health intervention to improve physical activity and mental health-related quality of life in people with chronic kidney disease (Kidney BEAM): A multi-centre, randomised controlled trial
The clinical value and cost effectiveness of a 6-month digital health intervention to improve physical activity and mental health-related quality of life in people with chronic kidney disease (Kidney BEAM): A multi-centre, randomised controlled trial Open
There is inequity in provision of physical rehabilitation services for people living with chronic kidney disease (CKD). The Kidney BEAM trial evaluated the clinical value and cost effectiveness of a physical activity digital health interve…
View article: Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort
Effects of rare kidney diseases on kidney failure: a longitudinal analysis of the UK National Registry of Rare Kidney Diseases (RaDaR) cohort Open
RaDaR is funded by the Medical Research Council, Kidney Research UK, Kidney Care UK, and the Polycystic Kidney Disease Charity.