Sunil Kumar Nanda
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View article: Cohort Profile for the Heat in Pregnancy- India (HiP-India) Study
Cohort Profile for the Heat in Pregnancy- India (HiP-India) Study Open
Background Extreme heat exposure — defined as sustained ambient temperatures exceeding local thresholds — has been associated with several adverse pregnancy outcomes, including preterm birth, stillbirth, gestational diabetes and small for …
View article: Cohort Profile for the Heat in Pregnancy- India (HiP-India) Study
Cohort Profile for the Heat in Pregnancy- India (HiP-India) Study Open
Background Extreme heat exposure — defined as sustained ambient temperatures exceeding local thresholds — has been associated with several adverse pregnancy outcomes, including preterm birth, stillbirth, gestational diabetes and small for …
View article: Evaluation of Clinical and Laboratory Parameters in Sepsis Patients with Elevated IL-6 Levels: An observational Analysis
Evaluation of Clinical and Laboratory Parameters in Sepsis Patients with Elevated IL-6 Levels: An observational Analysis Open
View article: Prediction Models for Gestational Diabetes Mellitus: Diagnostic Utility of Clinical and Biochemical Markers
Prediction Models for Gestational Diabetes Mellitus: Diagnostic Utility of Clinical and Biochemical Markers Open
Introduction: The use of oral glucose tolerance test (OGTT) is limited by an inconvenient procedure and poor reproducibility. This study aimed to develop and evaluate prediction models for gestational diabetes mellitus (GDM) diagnosis base…
View article: SHBG and Insulin Resistance - Nexus revisited
SHBG and Insulin Resistance - Nexus revisited Open
Sex hormone binding globulin (SHBG) is a liver-synthesized glycoprotein. Low SHBG levels are associated with insulin resistance (IR). Specific single nucleotide polymorphisms (SNPs) in the SHBG gene are linked to IR. Therefore, it is of in…
View article: Severe respiratory acidosis contributing to refractory hyperkalemia: a case series of COVID-19 patients with renal failure
Severe respiratory acidosis contributing to refractory hyperkalemia: a case series of COVID-19 patients with renal failure Open
Introduction: Respiratory acidosis (RA) is not known to cause severe hyperkalemia. However, an exception to this general rule was observed in three patients with severe COVID-19 complicated with renal failure in our center. Objectives: The…
View article: Calcium levels in acid concentrate are critical - A case series of post-hemodialysis hypercalcemia due to high calcium in acid concentrate
Calcium levels in acid concentrate are critical - A case series of post-hemodialysis hypercalcemia due to high calcium in acid concentrate Open
Introduction: There are very few studies on the discrepancies between prescribed and measured hemodialysis (HD) electrolyte levels, and most of the related studies address discrepancies in dialysate sodium concentrations. To the best of ou…
View article: Plasmapheresis can correct refractoriness of insulin on triglyceride metabolism – A case report of hypertriglyceridemia-induced acute pancreatitis
Plasmapheresis can correct refractoriness of insulin on triglyceride metabolism – A case report of hypertriglyceridemia-induced acute pancreatitis Open
Hypertriglyceridemia associated acute pancreatitis is a medical emergency and it causes significant morbidity and mortality. Here we report a case of 47 years old male with hypertriglyceridemia associated acute pancreatitis. The diagnosis …
View article: Effect of Statins on the Inflammatory Markers in Patients with Coronary Artery Disease
Effect of Statins on the Inflammatory Markers in Patients with Coronary Artery Disease Open
Introduction Atherosclerosis mediated by inflammatory markers is the corner stone in the pathology of coronary artery disease (CAD). Hyperlipidemia, one of the risk factors is treated with statins. Statins also have a pleotropic role in re…
View article: Association of Serum Pentraxin 3 and High-Sensitivity C-Reactive Protein with Severity of Coronary Stenosis
Association of Serum Pentraxin 3 and High-Sensitivity C-Reactive Protein with Severity of Coronary Stenosis Open
Background: Atherosclerosis being the keystone in the pathology of coronary artery disease (CAD) is a chronic inflammation of arterial intima mediated by various inflammatory markers. Pentraxin 3 (PTX3) and high-sensitivity C-reactive prot…
View article: Nell1 as Target Antigen for Mercury Related Membranous Nephropathy: A Case Report
Nell1 as Target Antigen for Mercury Related Membranous Nephropathy: A Case Report Open
Membranous nephropathy constitutes 30% of adult nephrotic syndrome. Of all cases of membranous nephropathy, primary membranous nephropathy is commonest. Mercury is known to be a cause of secondary membranous nephropathy. There is no human …
View article: Variations in Serum Vitamin B12 Levels among Metformin Receiving and Non-Receiving Type 2 Diabetes Mellitus Patients - A Case Control Study in a Tertiary Care Hospital in Puducherry
Variations in Serum Vitamin B12 Levels among Metformin Receiving and Non-Receiving Type 2 Diabetes Mellitus Patients - A Case Control Study in a Tertiary Care Hospital in Puducherry Open
BACKGROUND Metformin is considered as a cornerstone in the treatment of diabetes and is the most frequently prescribed first line therapy for individuals with T2DM. Metformin use in type 2 diabetes mellitus has shown to cause vitamin B12 (…
View article: A Comparative Study on the Diagnostic Utility of Creatine Kinase-MB (Myocardial Band) Mass Estimation Over Its Activity Measurement in Patients with Acute Myocardial Infarction in a Tertiary Care Hospital in Puducherry
A Comparative Study on the Diagnostic Utility of Creatine Kinase-MB (Myocardial Band) Mass Estimation Over Its Activity Measurement in Patients with Acute Myocardial Infarction in a Tertiary Care Hospital in Puducherry Open
BACKGROUND Cardiovascular diseases (CVDs) are one of the major health problems and leading cause of death worldwide. Acute myocardial infarction (AMI) is one of the cardiovascular diseases which has high mortality in early hours of present…
View article: Copeptin: Short term prognostic biomarker in ischemic stroke among Indian - A prospective cohort study
Copeptin: Short term prognostic biomarker in ischemic stroke among Indian - A prospective cohort study Open
Background: Copeptin a precursor of arginine vasopressin is associated with stroke severity and functional outcome among Chinese and Western population. We aimed to evaluate copeptin as a prognostic marker in patients with acute ischemic s…
View article: Cardiovascular risk using WHO-ISH chart among Diabetes and Hypertensive patients in a remote rural area of South India
Cardiovascular risk using WHO-ISH chart among Diabetes and Hypertensive patients in a remote rural area of South India Open
Cardiovascular disease risk assessment using WHO/ISH chart showed an association with poor education, anemia, and chronic kidney disease.
View article: Lipid accumulation product index as visceral obesity indicator in psoriasis: A Case–control Study
Lipid accumulation product index as visceral obesity indicator in psoriasis: A Case–control Study Open
Calculation of LAP index in psoriasis patients helps in identification of more individuals at high risk of cardiovascular morbidity than traditional anthropometric measurements of obesity.
View article: Correlation of Friedewald′s calculated low-density lipoprotein cholesterol levels with direct low-density lipoprotein cholesterol levels in a tertiary care hospital
Correlation of Friedewald′s calculated low-density lipoprotein cholesterol levels with direct low-density lipoprotein cholesterol levels in a tertiary care hospital Open
This study indicates calculated LDL by Friedewalds equation can be used instead of direct LDL in patients who cannot afford direct LDL method.
View article: Evaluation of leptin as a marker of insulin resistance in type 2 diabetes mellitus
Evaluation of leptin as a marker of insulin resistance in type 2 diabetes mellitus Open
Hyperleptinemia reflecting leptin resistance plays an important role in the development of IR in obeseT2DM patients, making leptin a possible biomarker for the same.
View article: Is dilution important: Factitious Total Creatine Kinase in case of Rhabdomyolysis?
Is dilution important: Factitious Total Creatine Kinase in case of Rhabdomyolysis? Open
Factitious test reports may result in incorrect diagnosis and incorrect management. Such incorrect diagnosis can be prevented by a vigilant biochemist. We report a case of Rhabdomyolysis presenting with extremely low total Creatine Kinase …
View article: A Study to Evaluate the Role of Antepartum and Intrapartum Factors Affecting Early Onset Neonatal Sepsis in Rural Medical College
A Study to Evaluate the Role of Antepartum and Intrapartum Factors Affecting Early Onset Neonatal Sepsis in Rural Medical College Open
The study was undertaken to study the maternal risk factors associated in the development of sepsis neonatorum (neonatal sepsis). The study was conducted in 70 neonates. Out of these 70 neonates, 27 were cases of neonatal sepsis and 43 ser…
View article: Prevalence of Metabolic Syndrome in Psoriasis Patients and its Relation to Disease Duration: A Hospital Based Case-Control Study
Prevalence of Metabolic Syndrome in Psoriasis Patients and its Relation to Disease Duration: A Hospital Based Case-Control Study Open
Our findings suggest that metabolic syndrome as well as dyslipidaemia is commoner in psoriasis patients. This underlines the need for screening of all psoriasis patients for early diagnosis and treatment of associated metabolic syndrome to…
View article: High atherogenic index of plasma in subclinical hypothyroidism: Implications in assessment of cardiovascular disease risk
High atherogenic index of plasma in subclinical hypothyroidism: Implications in assessment of cardiovascular disease risk Open
The positive association of dyslipidemia and SH indicates a need for regular screening of these patients to enable early diagnosis and treatment of dyslipidemia. Even in patients who have a normal conventional lipid profile, lipid ratios, …
View article: Agreement of Arterial Sodium and Arterial Potassium Levels with Venous Sodium and Venous Potassium in Patients Admitted to Intensive Care Unit
Agreement of Arterial Sodium and Arterial Potassium Levels with Venous Sodium and Venous Potassium in Patients Admitted to Intensive Care Unit Open
Arterial sodium and arterial potassium can be used instead of venous sodium and venous potassium levels in management of critically ill patients.
View article: A comparative study of serum aminotransferases in chronic kidney disease with and without end-stage renal disease: Need for new reference ranges
A comparative study of serum aminotransferases in chronic kidney disease with and without end-stage renal disease: Need for new reference ranges Open
Levels of serum aminotransferases were low in CKD with and without ESRD and the levels become lower as the severity of CKD increases. Thus, the study established the need for separate reference ranges of serum aminotransferase in different…