Sunil Nandi
YOU?
Author Swipe
View article: Isolation and Identification of a Potential Cellulose Degrading Bacterium Bacillus sp. Strain BCD1 from Cow Dung Sample
Isolation and Identification of a Potential Cellulose Degrading Bacterium Bacillus sp. Strain BCD1 from Cow Dung Sample Open
Cellulose polysaccharide is comprised with β-1,4 glycosidic linked D-glucose molecules and it became a most abundant organic substance in the environment. These resistant and water insoluble materials are majorly found in cell wall of plan…
View article: PRDM14 is essential for vertebrate gastrulation and safeguards avian germ cell identity
PRDM14 is essential for vertebrate gastrulation and safeguards avian germ cell identity Open
The zinc finger transcription factor PRDM14, part of the PR domain containing protein family, is critical for mammalian primordial germ cell (PGC) specification, epigenetic reprogramming and maintaining naïve pluripotency in stem cells. Ho…
View article: Prdm14 is Essential for Vertebrate Gastrulation and Safeguards Avian Germ Cell Identity
Prdm14 is Essential for Vertebrate Gastrulation and Safeguards Avian Germ Cell Identity Open
View article: The Transcriptome of Chicken Migratory Primordial Germ Cells Reveals Intrinsic Sex Differences and Expression of Hallmark Germ Cell Genes
The Transcriptome of Chicken Migratory Primordial Germ Cells Reveals Intrinsic Sex Differences and Expression of Hallmark Germ Cell Genes Open
Primordial germ cells (PGCs) are germline-restricted embryonic cells that form the functional gametes of the adult animal. The use of avian PGCs in biobanking and producing genetically modified birds has driven research on the in vitro pro…
View article: Estrogen suppresses DMRT1 protein expression during ovarian development in the chicken
Estrogen suppresses DMRT1 protein expression during ovarian development in the chicken Open
Primary sex determination determines the development of a bipotential gonad as a testis or as an ovary. DMRT1 gene is essential for testis development and estrogen has a role in ovariaogenesis. We find that estrogen suppresses DMRT1 protei…
View article: Estrogen suppresses DMRT1 expression during ovarian development in the chicken
Estrogen suppresses DMRT1 expression during ovarian development in the chicken Open
Primary sex determination is the choice between two different developmental fates, a testis or an ovary. This selection is thought to require the action of a master regulator gene that triggers expression of a gene cascade in the bipotenti…
View article: Avian Primordial Germ Cells Are Bipotent for Male or Female Gametogenesis
Avian Primordial Germ Cells Are Bipotent for Male or Female Gametogenesis Open
In birds, males are the homogametic sex (ZZ) and females are the heterogametic sex (ZW). Here, we investigate the role of chromosomal sex and germ cell competition on avian germ cell differentiation. We recently developed genetically steri…
View article: In the chick embryo, estrogen can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex, which supports oogenesis
In the chick embryo, estrogen can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex, which supports oogenesis Open
In chickens, the embryonic ovary differentiates into two distinct domains before meiosis: a steroidogenic core, the female medulla, overlain by the germ cell niche, the cortex. The differentiation of the medulla is a cell autonomous proces…
View article: Investigation of the Guinea fowl and domestic fowl hybrids as potential surrogate hosts for avian cryopreservation programmes
Investigation of the Guinea fowl and domestic fowl hybrids as potential surrogate hosts for avian cryopreservation programmes Open
View article: Reviving rare chicken breeds using genetically engineered sterility in surrogate host birds
Reviving rare chicken breeds using genetically engineered sterility in surrogate host birds Open
Significance In the fields of conservation biology and sustainable agriculture, the ability to cryopreserve and revive animal species is paramount to efforts to preserve genetic diversity. An innovative approach is to use sterile surrogate…
View article: In the chick embryo, estrogen can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex, which supports oogenesis
In the chick embryo, estrogen can induce chromosomally male ZZ left gonad epithelial cells to form an ovarian cortex, which supports oogenesis Open
In chickens, as in most amniotes, the first morphogenetic event in ovary differentiation is the formation of two distinct domains: a steroidogenic core, the medulla, overlain by the germ cell niche, the cortex. This process normally starts…
View article: Efficient TALEN-mediated gene targeting of chicken primordial germ cells
Efficient TALEN-mediated gene targeting of chicken primordial germ cells Open
In this work we use TALE nucleases (TALENs) to target a reporter construct to the DDX4 (vasa) locus in chicken primordial germ cells. Vasa is a key germ cell determinant in many animal species and is posited to control avian germ cell form…
View article: Real-Time Sexing of Chicken Embryos and Compatibility with in ovo Protocols
Real-Time Sexing of Chicken Embryos and Compatibility with in ovo Protocols Open
The chicken embryo is an established model system for studying early vertebrate development. One of the major advantages of this model is the facility to perform manipulations in ovo and then continue incubation and observe the effects on …
View article: Cell-Autonomous Sex Differences in Gene Expression in Chicken Bone Marrow–Derived Macrophages
Cell-Autonomous Sex Differences in Gene Expression in Chicken Bone Marrow–Derived Macrophages Open
We have identified differences in gene expression in macrophages grown from the bone marrow of male and female chickens in recombinant chicken M-CSF (CSF1). Cells were profiled with or without treatment with bacterial LPS for 24 h. Approxi…