Sunil Kumar Yadav
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View article: Comparison of modified varicose vein stripping with gauge packing versus conventional stripping in varicose veins – A prospective study
Comparison of modified varicose vein stripping with gauge packing versus conventional stripping in varicose veins – A prospective study Open
Background: Varicose veins are commonly treated with great saphenous vein (GSV) stripping, traditionally followed by external compression. A modified technique using gauge packing may offer advantages in specific settings. Aims and Objecti…
View article: Williams-Campbell Syndrome: An unusual case presentation.
Williams-Campbell Syndrome: An unusual case presentation. Open
View article: To study the anatomical variations at saphenofemoral junction in varicose veins
To study the anatomical variations at saphenofemoral junction in varicose veins Open
Background: Varicose veins are a common vascular condition affecting a significant proportion of the adult population and can cause symptoms ranging from cosmetic concerns to pain, edema, and ulceration. One of the primary anatomical sites…
View article: CRITICAL APPRAISAL OF LANGHANA THERAPY IN AYURVEDA WITH SPECIAL REFERENCE TO AUTOPHAGY: CELLULAR AND METABOLIC PERSPECTIVES
CRITICAL APPRAISAL OF LANGHANA THERAPY IN AYURVEDA WITH SPECIAL REFERENCE TO AUTOPHAGY: CELLULAR AND METABOLIC PERSPECTIVES Open
View article: A Rare Case of Localized Pigmented Villonodular Synovitis of the Wrist presenting as Carpal Tunnel Syndrome
A Rare Case of Localized Pigmented Villonodular Synovitis of the Wrist presenting as Carpal Tunnel Syndrome Open
Introduction: A form of tenosynovial giant cell tumors (GCTs) that diffusely affects the soft tissue lining of joints and tendons is called pigmented villonodular synovitis or PVNS. About equal percentages of men and women are often affect…
View article: Domestic Violence and Women Empowerment across Religion in India- A study on influence of various Determinants
Domestic Violence and Women Empowerment across Religion in India- A study on influence of various Determinants Open
The paper focus on influence of various determinants viz, General Nature (Religion, type of place of residence, State, Ethnicity, Caste, Education level of partners, justification of beating by women, alcohol consumption, type of relations…
View article: Giant Subcutaneous Fibrosarcoma in Goats
Giant Subcutaneous Fibrosarcoma in Goats Open
View article: Study of factors leading to cancellation of elective surgeries in a tertiary care hospital
Study of factors leading to cancellation of elective surgeries in a tertiary care hospital Open
Background: The postponement of elective surgeries is a major problem that increases the time for patients on surgical waiting lists and can negatively affect psychologically and physically to patients and their families. Cancellation rate…
View article: Chaplain care for health care colleagues: a scoping review
Chaplain care for health care colleagues: a scoping review Open
In addition to supporting patients and their loved ones at critical times, chaplains have long understood that caring for their health care colleagues is an important part of their practice. The Covid-19 pandemic prompted conversations amo…
View article: Comparison of In-Hospital Outcomes of Anterior Wall Versus Inferior Wall ST Elevation Myocardial Infarction Following Percutaneous Coronary Intervention: A Descriptive Cross-Sectional Study
Comparison of In-Hospital Outcomes of Anterior Wall Versus Inferior Wall ST Elevation Myocardial Infarction Following Percutaneous Coronary Intervention: A Descriptive Cross-Sectional Study Open
Introduction ST-elevation myocardial infarction (STEMI) is a critical condition affecting many individuals worldwide, posing significant risks to patient health and outcomes. Different types of STEMI, such as anterior wall and inferior wal…
View article: Ileo-sigmoid knotting presented as a rare cause of intestinal obstruction and bowel ischemia: A case report
Ileo-sigmoid knotting presented as a rare cause of intestinal obstruction and bowel ischemia: A case report Open
Ileosigmoid knotting causing intestinal obstruction is also known as double volvulus or compound volvulus. It is a rare cause of intestinal obstruction. It involves the sigmoid and ileum causing closed-loop intestinal obstruction. The endo…
View article: Ileo-sigmoid knotting presented as a rare cause of intestinal obstruction and bowel ischemia: A case report
Ileo-sigmoid knotting presented as a rare cause of intestinal obstruction and bowel ischemia: A case report Open
Ileosigmoid knotting causing intestinal obstruction is also known as double volvulus or compound volvulus. It is a rare cause of intestinal obstruction. It involves the sigmoid and ileum causing closed-loop intestinal obstruction. The endo…
View article: AN ANATOMICAL VARIATION OF GREAT SAPHENOUS VEIN : A RARE CASE REPORT
AN ANATOMICAL VARIATION OF GREAT SAPHENOUS VEIN : A RARE CASE REPORT Open
The longest vein in the body and a superficial vein of the leg is called the great saphenous vein (GSV, also known as the "long saphenous vein"). Blood is being brought back from the foot, leg, and thigh to the deep femoral vein at the sap…
View article: Evaluation of Pressure Pain Threshold for Marma Therapy Using Pressure Algometer: A Survey Study
Evaluation of Pressure Pain Threshold for Marma Therapy Using Pressure Algometer: A Survey Study Open
Marma Chikitsa is a gem of Ayurveda, a non-invasive therapy in which a very gentle stimulation of Marma points is done to instigate the flow of Prana which was occluded due to disturbed flow of Vata. To perform this therapy, a particular a…
View article: Isolated Gastric Perforation following Blunt Trauma Abdomen not to be Missed: A Case Series
Isolated Gastric Perforation following Blunt Trauma Abdomen not to be Missed: A Case Series Open
Abdominal trauma is a commonly encountered emergency which may be because of roadside accidents, assaults, or falls from height. Blunt injury to the abdomen is far more common than penetrating injury. Gastric perforation commonly occurs fo…
View article: Mechanistic basis for rescuing hypertrophic cardiomyopathy with myosin regulatory light chain phosphorylation
Mechanistic basis for rescuing hypertrophic cardiomyopathy with myosin regulatory light chain phosphorylation Open
We investigated the impact of the phosphomimetic (Ser15 → Asp15) myosin regulatory light chain (S15D‐RLC) on the Super‐Relaxed (SRX) state of myosin using previously characterized transgenic (Tg) S15D‐D166V rescue mice, comparing them to t…
View article: Acute Kidney Injury among Neonates with Perinatal Asphyxia in a Tertiary Care Centre
Acute Kidney Injury among Neonates with Perinatal Asphyxia in a Tertiary Care Centre Open
Introduction: Perinatal asphyxia is a very common cause of morbidity and mortality in both term and preterm neonates and ranks the second most important cause of neonatal death. The incidence and importance of acute kidney injury in the ne…
View article: Unraveling the nexus between educational deprivation and crime: An empirical study of the intersection of slum culture and social deviation in Daya Basti, India
Unraveling the nexus between educational deprivation and crime: An empirical study of the intersection of slum culture and social deviation in Daya Basti, India Open
View article: Serum Procalcitonin as a Biomarker for Diagnosing Neonatal Sepsis in a Tertiary Care Hospital of Eastern Nepal
Serum Procalcitonin as a Biomarker for Diagnosing Neonatal Sepsis in a Tertiary Care Hospital of Eastern Nepal Open
Background: Sepsis is the main cause of morbidity and mortality in neonates. Early diagnosis and appropriate treatment can reduce the mortality rate. Blood culture is the gold standard for diagnosis of bacterial sepsis, but it requires 3-5…
View article: Evaluation of Use of Fast Track Surgery
Evaluation of Use of Fast Track Surgery Open
Despite surgical and anesthetic advances, many studies show complications after major gastrointestinal surgery in a subset of patients. Studies have also shown that the main focus must be developing new therapies for postoperative benefit.…
View article: Profitability Analysis Of Selected IT Companies In India Using Data Envelopment Analysis (DEA): A Comprehensive Study
Profitability Analysis Of Selected IT Companies In India Using Data Envelopment Analysis (DEA): A Comprehensive Study Open
The IT sector in India plays a vital role in driving the country's economy, contributing significantly to its growth and employment landscape. As of 2023, it constitutes around 8% of India's total GDP, employing over 4.5 million profession…
View article: Prevalence of Iron Deficiency Anemia among Under Five Years Children in a Tertiary Health Care Center of Nepal
Prevalence of Iron Deficiency Anemia among Under Five Years Children in a Tertiary Health Care Center of Nepal Open
BackgroundGlobally 39.8% children under five years old are anemic, with prevalence of childhood anemia in Nepal reported to be 52.7% by 2016. The aim of this study is to analyze the prevalence of anemia among pediatric age group between 2 …
View article: Clinical Profile and Outcome of Children with Empyema Thoracis in Tertiary Hospital
Clinical Profile and Outcome of Children with Empyema Thoracis in Tertiary Hospital Open
Introduction: Empyema thoracis (ET) is an accumulation of pus in the pleural space. It is a common condition in childhood having significant morbidity and mortality. The clinical manifestations of empyema are high grade fever with chills a…
View article: P1364: PHARMACOKINETIC PROFILE OF VARNIMCABTAGENE AUTOLEUCEL (IMN-003A), FIRST-IN-INDIA INDUSTRY CD19-DIRECTED CAR-T CELL THERAPY FOR PATIENTS WITH RELAPSED/ REFRACTORY B CELL MALIGNANCIES (IMAGINE STUDY)
P1364: PHARMACOKINETIC PROFILE OF VARNIMCABTAGENE AUTOLEUCEL (IMN-003A), FIRST-IN-INDIA INDUSTRY CD19-DIRECTED CAR-T CELL THERAPY FOR PATIENTS WITH RELAPSED/ REFRACTORY B CELL MALIGNANCIES (IMAGINE STUDY) Open
Topic: 24. Gene therapy, cellular immunotherapy and vaccination - Biology & Translational Research Background: Varnimcabtagene autoleucel (IMN-003A) is an autologous CD19 directed CAR-T cell product with a 4-1BB co-stimulatory domain and A…
View article: Analysis of Neonatal Admission Patterns and Clinical Profiles in a Tertiary Care Center: Focus on Neonates Transferred from the Delivery Room to the Neonatal Intensive Care Unit
Analysis of Neonatal Admission Patterns and Clinical Profiles in a Tertiary Care Center: Focus on Neonates Transferred from the Delivery Room to the Neonatal Intensive Care Unit Open
Background: Neonatal mortality rate is very high in developing countries despite of advancement in perinatal and neonatal care with reduced neonatal mortality rate in many developed countries. This study aims to identify the reasons of adm…
View article: Clinico-Epidemiological Profile and Outcome of Poisoning in Children Presenting at a Tertiary Care Hospital of Eastern Nepal
Clinico-Epidemiological Profile and Outcome of Poisoning in Children Presenting at a Tertiary Care Hospital of Eastern Nepal Open
Background: Pediatric poisoning is common emergency worldwide and represents major and preventable cause of morbidity and mortality in children. The study describes epidemiology and outcome of acute poisonings in children presenting to Nob…
View article: Sepsis Screen Parameters in Blood Culture Positive Neonatal Sepsis
Sepsis Screen Parameters in Blood Culture Positive Neonatal Sepsis Open
Background: Neonatal sepsis is a clinical syndrome of bacteremia characterized by systemic signs and symptoms of infection in the first 28 days of life. Although, Positive blood culture is the gold standard for the diagnosis of neonatal se…
View article: A Comprehensive Review on Solid Dispersion Technique to Enhance the Solubility and Bioavailability of Poorly Water-Soluble Drugs
A Comprehensive Review on Solid Dispersion Technique to Enhance the Solubility and Bioavailability of Poorly Water-Soluble Drugs Open
The majority of the time, oral administration of medications to patients is chosen. However, many medications have limited uses in oral delivery due to their low solubility. In the pharmaceutical industry, improving a drug's water solubili…
View article: A Critical Review on Ancient and Modern Methodology of Cadaver Preservation with Special Reference to Technique Mentioned by Acharya Sushruta
A Critical Review on Ancient and Modern Methodology of Cadaver Preservation with Special Reference to Technique Mentioned by Acharya Sushruta Open
Medical courses are thought to have a unique defining feature that is learning Anatomy from a dissected cadaver. The study of the human body through cadaver dissection is very helpful in proliferation of medical knowledge possible. This wa…
View article: Diameter reflux relationship in perforating veins of patients with varicose veins and its correlation with clinical severity of disease
Diameter reflux relationship in perforating veins of patients with varicose veins and its correlation with clinical severity of disease Open
Treatment of chronic venous insufficiency requires understanding of the hemodynamics of perforating veins. Color Doppler analysis is the best modality to understand the hemodynamics of perforators. Perforating veins were categorized as com…