Sunithi Mani
YOU?
Author Swipe
View article: First Report of Dengue Virus in Sierra Leone: Implications for Arbovirus Surveillance and Control
First Report of Dengue Virus in Sierra Leone: Implications for Arbovirus Surveillance and Control Open
Dengue is the leading mosquito-borne viral cause of human illness and death. More than four billion people globally live at risk of Dengue Virus (DENV) infection and most infections are asymptomatic or present with a non-specific febrile i…
View article: ChatGPT as a Digital Pharmacist: A Systematic Review and Meta-Analysis of Drug-Counselling Accuracy
ChatGPT as a Digital Pharmacist: A Systematic Review and Meta-Analysis of Drug-Counselling Accuracy Open
Background The emergence of Large Language Models (LLMs) like ChatGPT presents significant opportunities for healthcare, yet raises concerns about accuracy, especially in high-risk areas such as medication counseling. A comprehensive evalu…
View article: Comparison between Transcutaneous Bilirubin and Serum Bilirubin levels in Late Preterm and Full-term Neonates in a tertiary care center in rural area of Southern Rajasthan
Comparison between Transcutaneous Bilirubin and Serum Bilirubin levels in Late Preterm and Full-term Neonates in a tertiary care center in rural area of Southern Rajasthan Open
Introduction: Neonatal hyperbilirubinemia is a common and potentially serious condition affecting a large proportion of term and preterm neonates. While total serum bilirubin (TSB) remains the gold standard for diagnosis, transcutaneous bi…
View article: Implications of Self-Construal for Affect and Well Being: An Indian Experience
Implications of Self-Construal for Affect and Well Being: An Indian Experience Open
The present study was conceptualized with a view to understand the differential effects of self-construal on positive and negative affect, life satisfaction, domain satisfaction and psychological wellbeing in Indian adults. Following a cro…
View article: Effectiveness of respiratory care modalities on biophysiological parameters among COPD patients at a tertiary care hospital in Chennai, India
Effectiveness of respiratory care modalities on biophysiological parameters among COPD patients at a tertiary care hospital in Chennai, India Open
Chronic Obstructive Pulmonary Disease (COPD) is one of the prevalent global health problems, with chronic respiratory symptoms and airflow limitation due to anatomic abnormalities primarily in the airways and alveoli. Therefore it is of in…
View article: Posterior Circulation Strokes – Clinico-Radiological Features and Predictors of Outcome at 6 Months
Posterior Circulation Strokes – Clinico-Radiological Features and Predictors of Outcome at 6 Months Open
Introduction: Posterior circulation stroke (PCS) is often diagnosed late and long-term outcomes have not been described in South India. We wished to study clinical features, long-term outcomes, and independent predictors of the same. Mater…
View article: Management of Severe Cerebral Venous Sinus Thrombosis Using Mechanical Balloon Assisted Thrombectomy
Management of Severe Cerebral Venous Sinus Thrombosis Using Mechanical Balloon Assisted Thrombectomy Open
Background Cerebral venous thrombosis is a devastating condition with, despite optimal medical management, a significant proportion deteriorating due to involvement of the deep venous system, worsening intracranial pressures, and hemorrhag…
View article: MRI Patterns in Pediatric CNS Hemophagocytic Lymphohistiocytosis
MRI Patterns in Pediatric CNS Hemophagocytic Lymphohistiocytosis Open
Distinct MR imaging patterns correlating with clinical phenotypes and possible genetic underpinnings were recognized in this cohort of pediatric CNS hemophagocytic lymphohistiocytosis. Disruptive mutations and missense mutations with absen…
View article: Brain networks and medical education
Brain networks and medical education Open
Background: There has been significant progress in understanding the human brain with the development of modalities like functional magnetic resonance imaging (fMRI), positron emission tomography (PET) etc. Education is an important source…
View article: Evaluation of Intracranial Vasculitis in Tuberculous Meningitis using Magnetic Resonance Vessel Wall Imaging Technique
Evaluation of Intracranial Vasculitis in Tuberculous Meningitis using Magnetic Resonance Vessel Wall Imaging Technique Open
Background: Tuberculous meningitis (TBM) is a global health problem with important complications such as acute infarcts secondary to vasculitis contributing to adverse outcomes. The objective of this study is to assess intracranial vasculi…
View article: Clinical Spectrum, Therapeutic Outcomes and Prognostic predictors in Paraneoplastic Neurological Syndromes – Experiences from a Tertiary Care Center in India
Clinical Spectrum, Therapeutic Outcomes and Prognostic predictors in Paraneoplastic Neurological Syndromes – Experiences from a Tertiary Care Center in India Open
Background: Paraneoplastic Neurological Syndromes (PNSs) are a heterogeneous group of immune-mediated disorders that often precede tumor diagnosis. There are few systematic studies on the spectrum and follow-up of PNSs. Objective: To analy…
View article: Development of a Unique Mouse Intervertebral Disc Degeneration Model Using a Simple Novel Tool
Development of a Unique Mouse Intervertebral Disc Degeneration Model Using a Simple Novel Tool Open
Study Design: Animal case control study.Purpose: To create a simple, reproducible disc degeneration model for mouse coccygeal vertebrae. Overview of Literature: Back pain due to disc degeneration is probably the most common problem encount…
View article: Clinical spectrum and outcome of neurosarcoidosis: A retrospective cohort study from a teaching hospital in India
Clinical spectrum and outcome of neurosarcoidosis: A retrospective cohort study from a teaching hospital in India Open
NS is a diverse illness, with a heterogeneous spectrum of clinical presentation, treatment response, and outcome. Cranial neuropathy is the most common presenting feature and has a good prognosis while myelopathy has an unfavorable prognos…
View article: Visual vignette- Nelson’s syndrome: a giant pituitary
Visual vignette- Nelson’s syndrome: a giant pituitary Open
Nelson’s syndrome is an infrequent pituitary mass with an incidence of 8–43% in adults and 25–66% in children that develops following total bilateral adrenalectomy (TBA) for the treatment of Cushing’s disease. It is one of the most challen…
View article: Clinical characteristics and complications of skull base osteomyelitis: A 12-year study in a teaching hospital in South India
Clinical characteristics and complications of skull base osteomyelitis: A 12-year study in a teaching hospital in South India Open
Bacterial infections are the most common cause of SBO. Otogenic SBO is associated with longer duration of diabetes mellitus and higher incidence of cranial nerve palsy. Therapeutic surgical debridement plays an important role in treatment …
View article: A review of extraaxial developmental venous anomalies of the brain involving dural venous flow or sinuses: persistent embryonic sinuses, sinus pericranii, venous varices or aneurysmal malformations, and enlarged emissary veins
A review of extraaxial developmental venous anomalies of the brain involving dural venous flow or sinuses: persistent embryonic sinuses, sinus pericranii, venous varices or aneurysmal malformations, and enlarged emissary veins Open
This paper is a narrative review of extraaxial developmental venous anomalies (eDVAs) of the brain involving dural venous flow or sinuses: persistent embryonic sinuses, sinus pericranii, enlarged emissary veins, and venous varices or aneur…
View article: Role of Noninvasive Imaging of Cerebral Arterial System in Ischemic Stroke: Comparison of Transcranial Color-coded Doppler Sonography with Magnetic Resonance Angiography
Role of Noninvasive Imaging of Cerebral Arterial System in Ischemic Stroke: Comparison of Transcranial Color-coded Doppler Sonography with Magnetic Resonance Angiography Open
Aim: To determine the accuracy of transcranial color-coded Doppler sonography (TCCS) in the evaluation of cerebral arterial system in patients with ischemic stroke attending a tertiary care hospital in South India. Objectives: (1) To descr…
View article: Brain Imaging in Cases with Positive Serology for Dengue with Neurologic Symptoms: A Clinicoradiologic Correlation
Brain Imaging in Cases with Positive Serology for Dengue with Neurologic Symptoms: A Clinicoradiologic Correlation Open
Although not specific, dengue infection has imaging findings that can be used to narrow down the differential list and help in prognostication.
View article: Management and Outcome in Patients with Advanced Juvenile Nasopharyngeal Angiofibroma
Management and Outcome in Patients with Advanced Juvenile Nasopharyngeal Angiofibroma Open
Objective To report the management outcome in a series of patients with advanced juvenile nasopharyngeal angiofibroma (JNA). Design Retrospective study. Setting Tertiary care teaching hospital. Participants Forty-five patients classified a…
View article: Spectrum of visual impairment in cerebral venous thrombosis: Importance of tailoring therapies based on pathophysiology
Spectrum of visual impairment in cerebral venous thrombosis: Importance of tailoring therapies based on pathophysiology Open
Visual impairment can complicate cerebral venous thrombosis (CVT). Here, we describe the various pathophysiological mechanisms and treatments available. A retrospective chart review of all patients treated for CVT in a large quaternary tea…
View article: Cavernous sinus melanoma: A rare tumor
Cavernous sinus melanoma: A rare tumor Open
Primay melanoma of the cavernous sinus is very rare with only few cases reported in the literature. We present the cross-sectional imaging findings of this rare tumor. The differential diagnosis for cavernous sinus mass lesion is wide as i…
View article: Role of penumbra mechanical thrombectomy device in acute dural sinus thrombosis
Role of penumbra mechanical thrombectomy device in acute dural sinus thrombosis Open
Background: In dural venous sinus thrombosis (DVST), the mortality ranges 5–30%. Deep venous system involvement and septic dural sinus thrombosis have a higher mortality rate. In acute occlusion, collateral flow may not be established, whi…
View article: Nelson’s syndrome: a giant pituitary
Nelson’s syndrome: a giant pituitary Open
Nelson’s syndrome is a pituitary mass that develops following total bilateral adrenalectomy (TBA) for the treatment of Cushing’s disease. It is one of the most challenging of all endocrine conditions. The frequent aggressiveness of the und…
View article: Pediatric Balint’s Syndrome Variant: A Possible Diagnosis in Children
Pediatric Balint’s Syndrome Variant: A Possible Diagnosis in Children Open
Balint’s syndrome is well described in adults, but not in children. It is caused by bilateral posterior parietal lobe damage and comprises a triad of simultanagnosia (inability to simultaneously see more than a small number of items), opti…
View article: Recurrent pericardial effusion and tamponade in a patient with Erdheim-Chester disease (ECD)
Recurrent pericardial effusion and tamponade in a patient with Erdheim-Chester disease (ECD) Open
Erdheim-Chester disease (ECD) is a rare xanthogranulomatous disorder characterised by the proliferation of lipid laden histiocytes along with infiltration of various organs of the body. Although commonly presenting with bone pains secondar…
View article: Cervical intramedullary schwannoma mimicking a glioma
Cervical intramedullary schwannoma mimicking a glioma Open
We present a case of a cervical intramedullary schwannoma (IS), which resembled a glioma on radiology. Somatic and root pain, the most common presenting complaints of IS, were lacking in our patient, and the characteristic magnetic resonan…
View article: Ornidazole-induced ataxia in an Indian woman: A case report
Ornidazole-induced ataxia in an Indian woman: A case report Open
The nitroimidazole group of antibiotics like metronidazole have been reported to cause cerebellar ataxia as a rare side effect. Ornidazole, the newest derivative of this class, has a long half life and is very rarely known to cause cerebel…
View article: Clinical, imaging and histopathological features of isolated CNS lymphomatoid granulomatosis
Clinical, imaging and histopathological features of isolated CNS lymphomatoid granulomatosis Open
Lymphomatoid granulomatosis is a rare systemic angiocentric/angiodestructive, B cell lymphoproliferative disorder. Central nervous system involvement occurs as part of systemic disease. Isolated central nervous system disease is rare with …
View article: Proximal Interruption of the Pulmonary Artery: A Case Series
Proximal Interruption of the Pulmonary Artery: A Case Series Open
We present a few cases of Proximal Interruption of the Pulmonary Artery, an uncommon developmental anomaly associated with congenital heart disease. The cases had varied clinical presentations. Chest radiograph showed a hypoplastic lung wi…