Sunmin Woo
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View article: Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments
Testing the Luedemann hypothesis: the discovery of novel antimicrobials from slow-growing microbes from nutrient-limited environments Open
George Luedemann is known throughout the antimicrobial community as one of the discoverers of the natural product antibiotic gentamicin. He subsequently hypothesized that slow-growing organisms inhabiting inhospitable, nutrient-limited env…
View article: Identification of Punicalagin as a Key Bioactive Compound Responsible for the Antimicrobial Properties of <i>Punica granatum</i> L. Peel Extract against <i>Staphylococcus aureus</i>
Identification of Punicalagin as a Key Bioactive Compound Responsible for the Antimicrobial Properties of <i>Punica granatum</i> L. Peel Extract against <i>Staphylococcus aureus</i> Open
This study highlights the potential of Punica granatum (pomegranate) peel extract (PPE) as a natural antimicrobial alternative to synthetic chemicals. Pomegranate peels, typically considered a byproduct of fruit processing, contain bioacti…
View article: High-Throughput Identification of Crystalline Natural Products from Crude Extracts Enabled by Microarray Technology and microED
High-Throughput Identification of Crystalline Natural Products from Crude Extracts Enabled by Microarray Technology and microED Open
The structural determination of natural products (NPs) can be arduous because of sample heterogeneity. This often demands iterative purification processes and characterization of complex molecules that may be available only in miniscule qu…
View article: Correction: Genetic and chemical markers for authentication of three Artemisia species: A. capillaris, A. gmelinii, and A. fukudo
Correction: Genetic and chemical markers for authentication of three Artemisia species: A. capillaris, A. gmelinii, and A. fukudo Open
[This corrects the article DOI: 10.1371/journal.pone.0264576.].
View article: High-throughput identification of crystalline natural products from crude extracts enabled by microarray technology and microED
High-throughput identification of crystalline natural products from crude extracts enabled by microarray technology and microED Open
The structural determination of natural products (NPs) can be arduous due to sample heterogeneity. This often demands itera-tive purification processes and characterization of complex molecules that may only be available in miniscule quant…
View article: Botanical inhibitors of SARS-CoV-2 viral entry: a phylogenetic perspective
Botanical inhibitors of SARS-CoV-2 viral entry: a phylogenetic perspective Open
Throughout the SARS-CoV-2 pandemic, the use of botanical dietary supplements in the United States has increased, yet their safety and efficacy against COVID-19 remains underexplored. The Quave Natural Product Library is a phylogenetically …
View article: Recent advances in the discovery of plant-derived antimicrobial natural products to combat antimicrobial resistant pathogens: insights from 2018–2022
Recent advances in the discovery of plant-derived antimicrobial natural products to combat antimicrobial resistant pathogens: insights from 2018–2022 Open
Plants produce a wide array of secondary metabolites capable of inhibiting pathways crucial for microbial survival and pathogenicity.
View article: Identification of Botanical Viral Entry Inhibitors for SARS‐CoV‐2
Identification of Botanical Viral Entry Inhibitors for SARS‐CoV‐2 Open
The examination of biodiversity across the world has historically been a critical part of drug development and led to the discovery of common medications for many medical issues including pain management, cancer, heart disease, and infecti…
View article: Genetic and chemical markers for authentication of three Artemisia species: A. capillaris, A. gmelinii, and A. fukudo
Genetic and chemical markers for authentication of three Artemisia species: A. capillaris, A. gmelinii, and A. fukudo Open
The genus Artemisia is an important source of medicines in both traditional and modern pharmaceutics, particularly in East Asia. Despite the great benefits of herbal medicine, quality assessment methods for these medicinal herbs are lackin…
View article: Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression
Linking a Gene Cluster to Atranorin, a Major Cortical Substance of Lichens, through Genetic Dereplication and Heterologous Expression Open
Lichens play significant roles in ecosystem function and comprise about 20% of all known fungi. Polyketide-derived natural products accumulate in the cortical and medullary layers of lichen thalli, some of which play key roles in protectio…
View article: Molecular Networking Reveals the Chemical Diversity of Selaginellin Derivatives, Natural Phosphodiesterase-4 Inhibitors from <i>Selaginella tamariscina</i>
Molecular Networking Reveals the Chemical Diversity of Selaginellin Derivatives, Natural Phosphodiesterase-4 Inhibitors from <i>Selaginella tamariscina</i> Open
Selaginellins are unique pigments found in the genus Selaginella, the largest genus of Lycopodiophyta. Recent studies reported that some selaginellin analogues have potent phosphodiesterase-4 (PDE4) inhibitory activity. In this study, the …
View article: The complete chloroplast genomes of two <i>Taraxacum</i> species, <i>T. platycarpum</i> Dahlst. and <i>T. mongolicum</i> Hand.-Mazz. (Asteraceae)
The complete chloroplast genomes of two <i>Taraxacum</i> species, <i>T. platycarpum</i> Dahlst. and <i>T. mongolicum</i> Hand.-Mazz. (Asteraceae) Open
Taraxacum platycarpum and Taraxacum mongolicum are perennial plants utilized for medicinal purposes in the family Asteraceae. The complete chloroplast genome sequences of the two species were characterized by de novo assembly with whole ge…