A. Gupta
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View article: Gastrointestinal Presentation of Eosinophilic Granulomatosis with Polyangiitis, Formerly Churg-Strauss Syndrome: A Case Report
Gastrointestinal Presentation of Eosinophilic Granulomatosis with Polyangiitis, Formerly Churg-Strauss Syndrome: A Case Report Open
Introduction: Some of the most common presentations of gastrointestinal diseases are nausea, vomiting, and generalized abdominal pain. These symptoms could also be associated with other diseases and require a structured approach to the spe…
View article: Identification of Safe Navigation Routes on the South Pole of the Moon using Chandrayaan Images
Identification of Safe Navigation Routes on the South Pole of the Moon using Chandrayaan Images Open
The Moon’s south pole offers extraordinary scientific opportunities, including studying permanently shadowed craters that may contain water ice and areas of constant sunlight ideal for solar power. However, its extreme terrain presents sig…
View article: Identification and Characterization of Abiotic Stress Induced novel UDP-Glucosyltransferase (UGT72L11) Gene from Glycyrrhiza glabra L.
Identification and Characterization of Abiotic Stress Induced novel UDP-Glucosyltransferase (UGT72L11) Gene from Glycyrrhiza glabra L. Open
The present study reports a unique broad spectrum UDP-glycosyltransferase from Glycyrrhiza glabra involved in multiple stress responses and abscisic acid mediated glycosylation. The identified UGT72L11 gene was cytoplasmic with ORF of 1425…
View article: HPLC-PDA Method for Quantification of Bioactive Compounds in Crude Extract and Fractions of Aucklandia costus Falc. and Cytotoxicity Studies against Cancer Cells
HPLC-PDA Method for Quantification of Bioactive Compounds in Crude Extract and Fractions of Aucklandia costus Falc. and Cytotoxicity Studies against Cancer Cells Open
Aucklandia costus Falc. (Synonym: Saussurea costus (Falc.) Lipsch.) is a perennial herb of the family Asteraceae. The dried rhizome is an essential herb in the traditional systems of medicine in India, China and Tibet. The important pharma…
View article: An assessment of the physicochemical characteristics and essential oil composition of Mentha longifolia (L.) Huds. exposed to different salt stress conditions
An assessment of the physicochemical characteristics and essential oil composition of Mentha longifolia (L.) Huds. exposed to different salt stress conditions Open
Salt stress adversely influences growth, development, and productivity in plants, resulting in a limitation on agriculture production worldwide. Therefore, this study aimed to investigate the effect of four different salts, i.e., NaCl, KCl…
View article: Correction: Chrysomycins A–C, antileukemic naphthocoumarins from <i>Streptomyces sporoverrucosus</i>
Correction: Chrysomycins A–C, antileukemic naphthocoumarins from <i>Streptomyces sporoverrucosus</i> Open
Correction for ‘Chrysomycins A–C, antileukemic naphthocoumarins from Streptomyces sporoverrucosus ’ by Shreyans K. Jain et al. , RSC Adv. , 2013, 3 , 21046–21053, https://doi.org/10.1039/c3ra42884b.
View article: Cocculus hirsutus-Derived Phytopharmaceutical Drug Has Potent Anti-dengue Activity
Cocculus hirsutus-Derived Phytopharmaceutical Drug Has Potent Anti-dengue Activity Open
Dengue is a serious public health concern worldwide, with ∼3 billion people at risk of contracting dengue virus (DENV) infections, with some suffering severe consequences of disease and leading to death. Currently, there is no broad use va…
View article: Natural podophyllotoxin analog 4DPG attenuates EMT and colorectal cancer progression via activation of checkpoint kinase 2
Natural podophyllotoxin analog 4DPG attenuates EMT and colorectal cancer progression via activation of checkpoint kinase 2 Open
Epithelial–mesenchymal transition (EMT) is critical for the metastatic dissemination of cancer cells and contributes to drug resistance. In this study, we observed that epithelial colorectal cancer (CRC) cells transiently exposed to 5-fluo…
View article: Enhanced in vitro production of diosgenin in shoot cultures of Dioscorea deltoidea by elicitation and precursor feeding
Enhanced in vitro production of diosgenin in shoot cultures of Dioscorea deltoidea by elicitation and precursor feeding Open
Background: Dioscorea deltoidea (Family: Dioscoreaceae) is a critically endangered medicinal plant widely used in traditional medicine and pharmaceutical industries for the preparation of appropriate drugs. The present study was conducted …
View article: <i>Cocculus hirsutus</i>-derived phytopharmaceutical drug has potent anti-dengue activity
<i>Cocculus hirsutus</i>-derived phytopharmaceutical drug has potent anti-dengue activity Open
Background Dengue is a serious public health concern worldwide, with ~3 billion people at risk of contracting dengue virus (DENV) infections. Currently, no effective vaccine or drug is available for the prevention or treatment of dengue, w…
View article: Enhanced in vitro production of diosgenin in shoot cultures of Dioscorea deltoidea by elicitation and precursor feeding
Enhanced in vitro production of diosgenin in shoot cultures of Dioscorea deltoidea by elicitation and precursor feeding Open
Background Dioscorea deltoidea (Family: Dioscoreaceae) is a critically endangered medicinal plant widely used in traditional medicine and pharmaceutical industries for the preparation of appropriate drugs. The present study was conducted t…
View article: FORMULATION AND CHARACTERIZATION OF MICROSPHERES OF NITAZOXANIDE BY CHEMICAL CROSSLINKING METHOD
FORMULATION AND CHARACTERIZATION OF MICROSPHERES OF NITAZOXANIDE BY CHEMICAL CROSSLINKING METHOD Open
The work investigated the design and evaluation of microspheres of Nitazoxanide by Ionotropic gelation technique met. 32 Factorial designs were used and concentration of polymer carbopol-934 (X1) and Ethyl cellulose (X2) were selected as t…
View article: Corrigendum: Mannitol Stress Directs Flavonoid Metabolism toward Synthesis of Flavones via Differential Regulation of Two Cytochrome P450 Monooxygenases in Coleus forskohlii
Corrigendum: Mannitol Stress Directs Flavonoid Metabolism toward Synthesis of Flavones via Differential Regulation of Two Cytochrome P450 Monooxygenases in Coleus forskohlii Open
[This corrects the article on p. 985 in vol. 7, PMID: 27458469.].
View article: Molecular and functional characterization of two isoforms of chalcone synthase and their expression analysis in relation to flavonoid constituents in Grewia asiatica L
Molecular and functional characterization of two isoforms of chalcone synthase and their expression analysis in relation to flavonoid constituents in Grewia asiatica L Open
Chalcone synthase constitutes a functionally diverse gene family producing wide range of flavonoids by catalyzing the initial step of the phenylpropanoid pathway. There is a pivotal role of flavonoids in pollen function as they are imperat…
View article: Mannitol Stress Directs Flavonoid Metabolism toward Synthesis of Flavones via Differential Regulation of Two Cytochrome P450 Monooxygenases in Coleus forskohlii
Mannitol Stress Directs Flavonoid Metabolism toward Synthesis of Flavones via Differential Regulation of Two Cytochrome P450 Monooxygenases in Coleus forskohlii Open
Cytochrome P450 monooxygenases (CYP450s) are known to play important roles in biosynthesis of all secondary metabolites, including flavonoids. Despite this, few CYP450s have been functionally characterized in model plants and roles of fewe…
View article: Functional Promiscuity of Two Divergent Paralogs of Type III Plant Polyketide Synthases
Functional Promiscuity of Two Divergent Paralogs of Type III Plant Polyketide Synthases Open
Plants effectively defend themselves against biotic and abiotic stresses by synthesizing diverse secondary metabolites, including health-protective flavonoids. These display incredible chemical diversity and ubiquitous occurrence and confe…