Explanipedia

MDCT Evaluation of Anastomotic Sites in Patients with Whipple Surgery: What Radiologists Need to Know Open

Nitin P. Ghonge, Surabhi Gupta · 2025

Whipple surgery, also known as pancreaticoduodenectomy, is a complex surgery used to treat neoplasms involving the pancreas, duodenum and common bile duct (CBD). It is a ‘resection and anastomosis’ surgery involving resection of the pancre…

Amelioration of lead nitrate induced pulmonary toxicity by Garlic essential oil in inflammatory markers of Swiss albino male mice Open

Surabhi Gupta, Veena Sharma · 2025

Lead is a toxic heavy metal that causes harmful effects on human health. Its prolonged use interferes with the pulmonary tissue, resulting in alterations in the normal level of transcription factors and cytokines. So, to restore these para…

Impact of aging endocrine milieu on prostate stromal-epithelial interactions Open

A Nagesh, Ankit Roy Choudhury, Nandana Devi, Surabhi Gupta, Pankaj Chaturvedi , et al. · 2024

The interplay between stromal and epithelial interactions is pivotal in the development and maintenance of various organs, including the prostate, an essential accessory gland in the male reproductive system. The prostate gland's developme…

Errata Title: Administration of Garlic Essential Oil Restored the Altered Enzymatic and Non-enzymatic Parameters and Pulmonary Histoarchitecture in Mice Subjected to Lead Nitrate Open

Surabhi Gupta, Veena Sharma · 2024

The focus of the current research work was to unfold the therapeutic potential of Garlic Essential Oil (GEO) in altered oxidative stress, biochemical parameters and histoarchitecture of pulmonary tissue of mice intoxicated with the inorgan…

Administration of Garlic Essential Oil Restored the Altered Enzymatic and Non-enzymatic Parameters and Pulmonary Histoarchitecture in Mice Subjected to Lead Nitrate Open

Surabhi Gupta, Veena Sharma · 2024

The focus of the current research work was to unfold the therapeutic potential of Garlic Essential Oil (GEO) in altered oxidative stress, biochemical parameters and histoarchitecture of pulmonary tissue of mice intoxicated with the inorgan…

<i>Calotropis procera</i> extract inhibits prostate cancer through regulation of autophagy Open

Palak Singh, Bodhana Dhole, Jaganmoy Choudhury, A. Tuli, Deepak Pandey , et al. · 2024

Current treatment options available for prostate cancer (PCa) patients have many adverse side effects and hence, new alternative therapies need to be explored. Anticancer potential of various phytochemicals derived from Calotropis procera …

Impact of Aging Endocrine Milieu on Prostate Stromal-Epithelial Interactions Open

A Nagesh, Ankit Roy Choudhury, Nandana Devi, Surabhi Gupta, Pradeep Kumar Chaturvedi , et al. · 2024

Effect of the Standardized ZnO/ZnO-GO Filter Element Substrate driven Advanced Oxidation Process on Textile Industry Effluent Stream: Detailed Analysis of Photocatalytic Degradation Kinetics Open

Kirtiman Singh, Shiwangi Maurya, Surabhi Gupta, Nihar Ranjan, Gurunath Ramanathan , et al. · 2023

A simple process of synthesizing coated filter element substrates (FES) containing zinc oxide (ZnO) nanorods and ZnO graphene-oxide nanocomposite for a pilot-scale industrial dye-effluent treatment plant is proposed. This work reports a de…

Ondansetron-induced QT prolongation among various age groups: a systematic review and meta-analysis Open

Kamaldeep Singh, Arpit Jain, Ishita Panchal, Hritik Madan, Anubhav Gupta , et al. · 2023

Disseminated uterine actinomycosis: A case report and review of literature Open

Nitin P. Ghonge, Surabhi Gupta, Sarika Gupta, Seema Singhal · 2023

Actinomyces - It mainly affects the cervicofacial and abdominopelvic organs. These bacteria are of low virulence and their spread requires breakdown or alteration of the normal tissue barrier, which can be due to any surgery, trauma, or in…

Monosodium Glutamate Perturbs Human Trophoblast Invasion and Differentiation through a Reactive Oxygen Species-Mediated Pathway: An In-Vitro Assessment Open

Indrani Mukherjee, Subhrajit Biswas, Sunil Singh, Joyeeta Talukdar, Mohammed S. Alqahtani , et al. · 2023

The overproduction of reactive oxygen species (ROS) has been associated with various human diseases. ROS exert a multitude of biological effects with both physiological and pathological consequences. Monosodium glutamate (MSG), a sodium sa…

Role of Procalcitonin as a Biomarker in Early Identification of Adverse Events Following Esophageal Atresia Surgery Open

Dhruv Mahajan, Prabudh Goel, Vishesh Jain, Anjan Kumar Dhua, Ajay Verma , et al. · 2023

Introduction: Surgical complication following esophageal atresia repair is one of the several factors known to influence the final outcomes. Early identification of such complications may help in timely institution of therapeutic measures …

Novel quasi-mesenchymal state of extravillous trophoblasts and its regulation during pregnancy Open

Jaganmoy Choudhury, Kanika Kanika, Pradeep Kumar Chaturvedi, Surabhi Gupta · 2022

An appropriately functional placenta is the key to a successful and healthy pregnancy. During human placentation, the cytotrophoblast cells (CTBs) differentiate into the extravillous trophoblast cells (EVTs) that invade the maternal endome…

Monosodium glutamate (MSG) perturbs trophoblast differentiation and invasion program through a ROS mediated pathway Open

Indrani Mukherjee, Sunil Singh, Subhrajit Biswas, Joyeeta Talukdar, Mohammed S. Alqahtani , et al. · 2022

Monosodium glutamate (MSG) is a flavor-enhancing food additive widely used in Asian cuisine. It is one of the common ingredients used in curry and other tinned food that is believed to bring out the "umami" meat flavor and enhance the savo…

Association of inflammatory markers with the disease & mutation status in pancreatic cancer Open

Nidhi Singh, Surabhi Gupta, Sumaira Rashid, Anoop Saraya · 2022

Background & objectives Inflammation has been studied to be an important contributory factor to carcinogenesis through pro-inflammatory markers such as interleukin (IL)-6 and C-reactive protein (CRP). Furthermore, K-ras mutation is an impo…

Role of Cord Blood Albumin and Bilirubin for Prediction of Significant Neonatal Jaundice Open

Nidhi Gupta, Shachi Jain Taran, Surabhi Gupta, Kewal kishore Arora · 2021

Introduction: Nearly 60-80% of the term and preterm neonates are affected due to rise in bilirubin levels during early postnatal days, and causes readmission of the neonate sometimes with severe jaundice, which can be reduced if neonatal h…

Panel of serum miRNAs as potential non-invasive biomarkers for pancreatic ductal adenocarcinoma Open

Imteyaz Ahmad Khan, Safoora Rashid, Nidhi Singh, Sumaira Rashid, Vishwajeet Singh , et al. · 2021

A Novel Antigonadotropic Role of Thyroid Stimulating Hormone on Leydig Cell-Derived Mouse Leydig Tumor Cells-1 Line Open

Bodhana Dhole, Surabhi Gupta, Skand Shekhar, Anand Kumar · 2020

Subclinical hypothyroid men characterized by a rise in only thyroid stimulating hormone (TSH) levels, and normal thyroid hormone levels showed a fall in their serum progesterone and testosterone levels. This suggested a role of TSH in regu…

SAT-LB9 Anti-Cancer Properties of RISUG Against Prostrate Cancer Cell Line PC-3 -Invitro Study Open

Pankaj Singroul, Palak Singh, Sujoy K. Guha, Surabhi Gupta, Pradeep Kumar Chaturvedi · 2020

Cancer cell lines were initially established for understanding the genetic, functional, and epigenetic properties of cancer cells. The PC3 cell line is a human-derived prostate cancer cell line from the metastatic bone site of the grade IV…

Clinical significance of promoter methylation status of tumor suppressor genes in circulating DNA of pancreatic cancer patients Open

Nidhi Singh, Sumaira Rashid, Safoora Rashid, Nihar Ranjan Dash, Surabhi Gupta , et al. · 2020

Mechanobiology of Cancer Stem Cells and Their Niche Open

Ankit Roy Choudhury, Surabhi Gupta, Pradeep Kumar Chaturvedi, Neeraj Kumar, Deepak Pandey · 2019

Recurrent Abortions Presenting with Congenital Absence of Inferior Vena Cava in a Young Female Open

Surabhi Gupta, Neha Nischal · 2019

Inferior Vena Cava (IVC) agenesis is an unusual cause of deep vein thrombosis, particularly in young individuals. We report a case of a 28-year-old Indian female presenting with recurrent abortions, multiple episodes of deep vein thrombosi…

Triiodothyronine stimulates VEGF expression and secretion via steroids and HIF-1α in murine Leydig cells Open

Bodhana Dhole, Surabhi Gupta, Senthil Kumar Venugopal, Anand Kumar · 2018

8-Br-cAMP: 8-bromo - 3', 5' cyclic adenosine monophosphate; CoCl₂: cobalt chloride; HIF-1α: hypoxia inducible factor -1α; LH: luteinizing hormone; T₃: 3, 5, 3'-L-triiodothyronine; VEGF: vascular endothelial growth fac…

Prognostic significance of plasma matrix metalloprotease-2 in pancreatic cancer patients Open

Nidhi Singh, Surabhi Gupta, Ravindra Mohan Pandey, Peush ‎Sahni, Shyam S. Chauhan , et al. · 2017

Background & objectives: Pancreatic cancer has a propensity for wide stromal invasion. Matrix metalloprotease-2 (MMP-2) is a protease that degrades the peri-tumoural tissue and helps in tumour dissemination. Thus, this study was aimed to a…

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