Sagar S. Patel
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View article: Orca-T versus allogeneic hematopoietic stem cell transplantation (PRECISION-T): a multicenter, randomized phase 3 trial
Orca-T versus allogeneic hematopoietic stem cell transplantation (PRECISION-T): a multicenter, randomized phase 3 trial Open
To prevent graft-versus-host disease (GVHD) in patients undergoing myeloablative allogeneic hematopoietic stem cell transplantation (alloHSCT), a calcineurin inhibitor plus methotrexate is routinely used. Early phase studies suggested impr…
View article: Orca-T improves chronic graph-versus-host disease free in patients with a broad range of demographic and clinical variables: Results of randomized, Phase 3 trial
Orca-T improves chronic graph-versus-host disease free in patients with a broad range of demographic and clinical variables: Results of randomized, Phase 3 trial Open
BACKGROUND Orca-T is an investigational allogeneic T-cell immunotherapy using purified donor regulatory T cells to prevent graft-versus-host disease (GvHD). The randomized phase 3 Precision-T trial (NCT05316701) showed improved moderate-to…
View article: Predictors of In-Hospital Mortality Among Patients With Acute Stroke: Insights From the Healthcare Cost and Utilization Project (HCUP) Nationwide Readmission Database
Predictors of In-Hospital Mortality Among Patients With Acute Stroke: Insights From the Healthcare Cost and Utilization Project (HCUP) Nationwide Readmission Database Open
View article: Navigating Blame: Examining Prevalent Mother-Blame Attitudes in Epigenetic Discourse
Navigating Blame: Examining Prevalent Mother-Blame Attitudes in Epigenetic Discourse Open
View article: Analysis of Neurosyphilis Imaging Methods and Treatment: A Focused Review
Analysis of Neurosyphilis Imaging Methods and Treatment: A Focused Review Open
View article: Supplementary Figure S4 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S4 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CTX131 construct
View article: Supplementary Table S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Table S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Summary of Treatment-Related TEAEs in Safety Analysis Set by Dose Level
View article: Supplementary Table S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Table S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Flow Cytometry Antibody Panel
View article: Supplementary Figure S3 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S3 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CTX130 construct
View article: Supplementary Figure S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Cytokine secretion during CAR T-cell activation upon coculture with CD70+ RCC cells
View article: Supplementary Figure S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Cytokine secretion during CAR T-cell activation upon coculture with CD70+ RCC cells
View article: Supplementary Table S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Table S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Summary of Treatment-Related TEAEs in Safety Analysis Set by Dose Level
View article: Supplementary Table S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Table S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Flow Cytometry Antibody Panel
View article: Supplementary Figure S4 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S4 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CTX131 construct
View article: Supplementary Figure S6 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S6 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CONSORT flow diagram for COBALT-RCC trial design schematic
View article: Supplementary Figure S5 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S5 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
COBALT-RCC trial design schematic
View article: Supplementary Figure S3 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S3 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CTX130 construct
View article: Supplementary Figure S6 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S6 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CONSORT flow diagram for COBALT-RCC trial design schematic
View article: Supplementary Figure S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Tumor biopsy CD70 H-scores
View article: Supplementary Figure S5 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S5 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
COBALT-RCC trial design schematic
View article: Supplementary Figure S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Tumor biopsy CD70 H-scores
View article: Ultrafiltration Patterns during Automated Peritoneal Dialysis: Findings and Insights to Peritoneal Physiology
Ultrafiltration Patterns during Automated Peritoneal Dialysis: Findings and Insights to Peritoneal Physiology Open
Key Points There is a consistent increase in ultrafiltration volumes achieved per cycle over the course of an automated peritoneal dialysis treatment session. A better understanding of intercycle ultrafiltration trends may inform prescript…
View article: Supplementary Figure S6 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S6 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CONSORT flow diagram for COBALT-RCC trial design schematic
View article: Supplementary Figure S4 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S4 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CTX131 construct
View article: Supplementary Figure S6 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S6 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CONSORT flow diagram for COBALT-RCC trial design schematic
View article: Supplementary Table S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Table S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Summary of Treatment-Related TEAEs in Safety Analysis Set by Dose Level
View article: Supplementary Figure S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S1 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Tumor biopsy CD70 H-scores
View article: Supplementary Table S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Table S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Flow Cytometry Antibody Panel
View article: Supplementary Figure S4 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S4 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
CTX131 construct
View article: Supplementary Figure S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma
Supplementary Figure S2 from CD70-Targeted Allogeneic CAR T-Cell Therapy for Advanced Clear Cell Renal Cell Carcinoma Open
Cytokine secretion during CAR T-cell activation upon coculture with CD70+ RCC cells