Suresh Subramani
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View article: Differential Expression of Hard Tissue Proteins in Hypomineralized Second Primary Molars in Comparison to Normal Teeth
Differential Expression of Hard Tissue Proteins in Hypomineralized Second Primary Molars in Comparison to Normal Teeth Open
Objective This study aims to identify the proteins in hypomineralized second primary molars (HSPMs) and correlate their function in Amelogenesis. HSPM is a qualitative defect of the enamel of the second primary molars with no clear etiolog…
View article: Sociogenomics: Gene-environment Interactions in Enamel Defects
Sociogenomics: Gene-environment Interactions in Enamel Defects Open
Sociogenomics, an interdisciplinary field at the intersection of genomics and social sciences, offers a unique lens to understand the complex interplay between genetic predispositions and social/environmental influences on human health. Wh…
View article: TOR and heat shock response pathways regulate peroxisome biogenesis during proteotoxic stress
TOR and heat shock response pathways regulate peroxisome biogenesis during proteotoxic stress Open
Peroxisomes are versatile organelles mediating energy homeostasis and redox balance. While peroxisome dysfunction is linked to numerous diseases, the molecular mechanisms and signaling pathways regulating peroxisomes during cellular stress…
View article: Achieving Health Equity and Resilience: Leveraging Information for Sustainable Global Health Solutions
Achieving Health Equity and Resilience: Leveraging Information for Sustainable Global Health Solutions Open
The report explores the transformative potential of data-driven approaches in achieving global health equity and resilience, aligned with the 2030 Agenda for Sustainable Development. The paper emphasizes the interconnections between social…
View article: Bulk and selective autophagy cooperate to remodel a fungal proteome in response to changing nutrient availability
Bulk and selective autophagy cooperate to remodel a fungal proteome in response to changing nutrient availability Open
Cells remodel their proteomes in response to changing environments by coordinating changes in protein synthesis and degradation. In yeast, such degradation involves both proteasomal and vacuolar activity, with a mixture of bulk and selecti…
View article: Automated, image-based quantification of peroxisome characteristics with <i>perox-per-cell</i>
Automated, image-based quantification of peroxisome characteristics with <i>perox-per-cell</i> Open
Summary perox-per-cell automates cumbersome, image-based data collection tasks often encountered in peroxisome research. The software processes microscopy images to quantify peroxisome features in yeast cells. It uses off-the-shelf image p…
View article: Automated, image-based quantification of peroxisome characteristics with<i>perox-per-cell</i>
Automated, image-based quantification of peroxisome characteristics with<i>perox-per-cell</i> Open
perox-per-cell automates cumbersome, image-based data collection tasks often encountered in peroxisome research. The software processes microscopy images to quantify peroxisome features in yeast cells. It uses off-the-shelf image processin…
View article: Aeroplane wing, a new recessive autosomal phenotypic marker in the malaria vector, Anopheles stephensi Liston
Aeroplane wing, a new recessive autosomal phenotypic marker in the malaria vector, Anopheles stephensi Liston Open
View article: Convergent and divergent mechanisms of peroxisomal and mitochondrial division
Convergent and divergent mechanisms of peroxisomal and mitochondrial division Open
Organelle division and segregation are important in cellular homeostasis. Peroxisomes (POs) and mitochondria share a core division machinery and mechanism of membrane scission. The division of each organelle is interdependent not only on t…
View article: Aeroplane wing, a new recessive autosomal phenotypic marker in malaria vector,<i>Anopheles stephensi</i>Liston
Aeroplane wing, a new recessive autosomal phenotypic marker in malaria vector,<i>Anopheles stephensi</i>Liston Open
A novel and distinct mutant, with an aeroplane wing ( ae ) phenotype, is reported for the first time in the urban malaria vector, Anopheles stephensi . The mutant mosquitoes exhibit extended wings that are easily visible to naked eyes in b…
View article: Enrichment of phenotype among biological forms of Anopheles stephensi Liston through establishment of isofemale lines
Enrichment of phenotype among biological forms of Anopheles stephensi Liston through establishment of isofemale lines Open
Background Vector management programs rely on knowledge of the biology and genetic make-up of mosquitoes. Anopheles stephensi is a major invasive urban malaria vector, distributed throughout the Indian subcontinent and Middle East, and has…
View article: Aeroplane Wing, a New Recessive Autosomal Phenotypic Marker in Malaria Vector, Anopheles Stephensi Liston
Aeroplane Wing, a New Recessive Autosomal Phenotypic Marker in Malaria Vector, Anopheles Stephensi Liston Open
View article: Identification of a TNF-TNFR-like system in malaria vectors (Anopheles stephensi) likely to influence Plasmodium resistance
Identification of a TNF-TNFR-like system in malaria vectors (Anopheles stephensi) likely to influence Plasmodium resistance Open
Identification of Plasmodium -resistance genes in malaria vectors remains an elusive goal despite the recent availability of high-quality genomes of several mosquito vectors. Anopheles stephensi, with its three distinctly-identifiable form…
View article: Enrichment of phenotype among biological forms of<i>Anopheles stephensi</i>Liston through establishment of isofemale lines
Enrichment of phenotype among biological forms of<i>Anopheles stephensi</i>Liston through establishment of isofemale lines Open
The success of vector management programs relies on knowledge of the biology and genetic make-up of mosquitoes so that they can be interlaced with modern tools for developing suitable intervention strategies. There are many reports availab…
View article: Identification of a TNF-TNFR-like system in malaria vectors (Anopheles stephensi) likely to influence Plasmodium resistance
Identification of a TNF-TNFR-like system in malaria vectors (Anopheles stephensi) likely to influence Plasmodium resistance Open
Identification of Plasmodium -resistance genes in malaria vectors remains an elusive goal despite the recent availability of high-quality genomes of several mosquito vectors. An. stephensi , with its three distinctly-identifiable forms at …
View article: Identification of a TNF-TNFR-like system in malaria vectors (<i>Anopheles stephensi</i>) likely to influence <i>Plasmodium</i> resistance
Identification of a TNF-TNFR-like system in malaria vectors (<i>Anopheles stephensi</i>) likely to influence <i>Plasmodium</i> resistance Open
Identification of Plasmodium -resistance genes in malaria vectors remains an elusive goal despite the recent availability of high-quality genomes of several mosquito vectors. An. stephensi, with its three distinctly-identifiable forms at t…
View article: Author Correction: Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly
Author Correction: Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly Open
View article: OXPHOS deficiencies affect peroxisome proliferation by downregulating genes controlled by the SNF1 signaling pathway
OXPHOS deficiencies affect peroxisome proliferation by downregulating genes controlled by the SNF1 signaling pathway Open
How environmental cues influence peroxisome proliferation, particularly through organelles, remains largely unknown. Yeast peroxisomes metabolize fatty acids (FA), and methylotrophic yeasts also metabolize methanol. NADH and acetyl-CoA, pr…
View article: Author response: OXPHOS deficiencies affect peroxisome proliferation by downregulating genes controlled by the SNF1 signaling pathway
Author response: OXPHOS deficiencies affect peroxisome proliferation by downregulating genes controlled by the SNF1 signaling pathway Open
Article Figures and data Abstract Editor's evaluation Introduction Results Discussion Materials and methods Data availability References Decision letter Author response Article and author information Metrics Abstract How environmental cues…
View article: The genome trilogy of Anopheles stephensi, an urban malaria vector, reveals structure of a locus associated with adaptation to environmental heterogeneity
The genome trilogy of Anopheles stephensi, an urban malaria vector, reveals structure of a locus associated with adaptation to environmental heterogeneity Open
View article: Recognition and Chaperoning by Pex19, Followed by Trafficking and Membrane Insertion of the Peroxisome Proliferation Protein, Pex11
Recognition and Chaperoning by Pex19, Followed by Trafficking and Membrane Insertion of the Peroxisome Proliferation Protein, Pex11 Open
Pex11, an abundant peroxisomal membrane protein (PMP), is required for division of peroxisomes and is robustly imported to peroxisomal membranes. We present a comprehensive analysis of how the Pichia pastoris Pex11 is recognized and chaper…
View article: Molecular Mechanisms and Physiological Significance of Organelle Interactions and Cooperation - Volume II
Molecular Mechanisms and Physiological Significance of Organelle Interactions and Cooperation - Volume II Open
Eukaryotic cells contain distinct membrane-bound organelles, which compartmentalize cellular proteins to fulfil a variety of vital functions. In contrast to being isolated and static entities (e.g., peroxisomes, mitochondria, lipid droplet…
View article: Decision letter: The peroxisomal exportomer directly inhibits phosphoactivation of the pexophagy receptor Atg36 to suppress pexophagy in yeast
Decision letter: The peroxisomal exportomer directly inhibits phosphoactivation of the pexophagy receptor Atg36 to suppress pexophagy in yeast Open
View article: The genome trilogy of <i>Anopheles stephensi</i>, an urban malaria vector, reveals structure of a locus associated with adaptation to environmental heterogeneity
The genome trilogy of <i>Anopheles stephensi</i>, an urban malaria vector, reveals structure of a locus associated with adaptation to environmental heterogeneity Open
Background Anopheles stephensi is the most menacing malaria vector to watch for in newly urbanizing parts of the world. The fitness is reported to be a direct consequence of the vector adapting to laying eggs in over-head water tanks with …
View article: OXPHOS deficiencies affect peroxisome proliferation by downregulating genes controlled by the SNF1 signaling pathway
OXPHOS deficiencies affect peroxisome proliferation by downregulating genes controlled by the SNF1 signaling pathway Open
Summary How environmental cues influence peroxisome proliferation, particularly through other organelles, remains largely unknown. Yeast peroxisomes metabolize all fatty acids (FA), and methylotrophic yeasts also metabolize methanol. NADH …
View article: Knowledge And Attitudes Of Obesity Among Rural People: A Sociological Analysis
Knowledge And Attitudes Of Obesity Among Rural People: A Sociological Analysis Open
Health Is Essential For Organized Social Life. If Societies Are To Function Smoothly And Effectively, The Members Must Be So Healthy As To Engage In Productive Actives. It Is Only When Their Health Is Sound That They Can Engage In Producti…
View article: BiFC Method Based on Intraorganellar Protein Crowding Detects Oleate-Dependent Peroxisomal Targeting of Pichia pastoris Malate Dehydrogenase
BiFC Method Based on Intraorganellar Protein Crowding Detects Oleate-Dependent Peroxisomal Targeting of Pichia pastoris Malate Dehydrogenase Open
The maintenance of intracellular NAD+/NADH homeostasis across multiple, subcellular compartments requires the presence of NADH-shuttling proteins, which circumvent the lack of permeability of organelle membranes to these cofactors. Very li…
View article: Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly
Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly Open
View article: Additional file 5 of Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly
Additional file 5 of Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly Open
Additional file 5: Table S5 Coordinates of putative Y-linked genes supported by multiple uniquely mapping Iso-Seq reads.
View article: Additional file 8 of Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly
Additional file 8 of Hidden genomic features of an invasive malaria vector, Anopheles stephensi, revealed by a chromosome-level genome assembly Open
Additional file 8: Table S8. Classification of putative immune-related proteins of An. stephensi.