Susan E. Mackinnon
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View article: The Super-Turbocharged End-to-Side Abductor Digiti Minimi and Anterior Interosseous Double Nerve Transfer Is Associated With Improved Ulnar Intrinsic Function.
The Super-Turbocharged End-to-Side Abductor Digiti Minimi and Anterior Interosseous Double Nerve Transfer Is Associated With Improved Ulnar Intrinsic Function. Open
BACKGROUND: Nerve transfers to reinnervate ulnar intrinsic musculature can restore function in severe ulnar neuropathy, and supercharged end-to-side (SETS) nerve transfers have garnered early adoption. Given the relative expendability of t…
View article: The Super-Turbocharged End-to-Side Abductor Digiti Minimi and Anterior Interosseous Double Nerve Transfer Is Associated With Improved Ulnar Intrinsic Function
The Super-Turbocharged End-to-Side Abductor Digiti Minimi and Anterior Interosseous Double Nerve Transfer Is Associated With Improved Ulnar Intrinsic Function Open
Background: Nerve transfers to reinnervate ulnar intrinsic musculature can restore function in severe ulnar neuropathy, and supercharged end-to-side (SETS) nerve transfers have garnered early adoption. Given the relative expendability of t…
View article: Compression of the Ulnar Nerve by the Arcade of Struthers: Look and You Shall Find.
Compression of the Ulnar Nerve by the Arcade of Struthers: Look and You Shall Find. Open
BACKGROUND: The arcade of Struthers was first proposed by Kane et al in 1973. Clinical investigations of this structure have been limited to small case series, focusing on the arcade as an isolated cause of compressive ulnar neuropathy. Th…
View article: Limited Nerve Regeneration across Acellular Nerve Allografts (ANAs) Coincides with Changes in Blood Vessel Morphology and the Development of a Pro-Inflammatory Microenvironment
Limited Nerve Regeneration across Acellular Nerve Allografts (ANAs) Coincides with Changes in Blood Vessel Morphology and the Development of a Pro-Inflammatory Microenvironment Open
The use of acellular nerve allografts (ANAs) to reconstruct long nerve gaps (>3 cm) is associated with limited axon regeneration. To understand why ANA length might limit regeneration, we focused on identifying differences in the regenerat…
View article: SP56. Effects Of Systemic T Cell Modulation On Nerve Regeneration After Segmental Injury
SP56. Effects Of Systemic T Cell Modulation On Nerve Regeneration After Segmental Injury Open
Purpose: The immune system plays a critical role in peripheral nerve regeneration. Previous work from our lab has shown endogenous CD4 T cells contribute to nerve regeneration after segmental injury. Therefore, we further investigated the …
View article: 71. Peripheral Nerve Injury After Deoxycholic Acid (Kybella) Injection
71. Peripheral Nerve Injury After Deoxycholic Acid (Kybella) Injection Open
Purpose: Deoxycholic acid (Kybella) is a drug commonly injected in non-surgical aesthetic procedures to locally reduce subcutaneous fat. Kybella treatment has been reported to have adverse effects, one of which can cause marginal mandibula…
View article: Compression of the Ulnar Nerve by the Arcade of Struthers: Look and You Shall Find
Compression of the Ulnar Nerve by the Arcade of Struthers: Look and You Shall Find Open
Background: The arcade of Struthers was first proposed by Kane et al in 1973. Clinical investigations of this structure have been limited to small case series, focusing on the arcade as an isolated cause of compressive ulnar neuropathy. Th…
View article: Patient Outcomes After Peripheral Nerve Injury Depend on Bimanual Dexterity and Preserved Use of the Affected Hand
Patient Outcomes After Peripheral Nerve Injury Depend on Bimanual Dexterity and Preserved Use of the Affected Hand Open
Background Little is known about how peripheral nerve injury affects human performance, behavior, and life. Hand use choices are important for rehabilitation after unilateral impairment, but rarely measured, and are not changed by the norm…
View article: Brachial Gunshot Wounds: Injury Patterns and Considerations for Managing the Abnormal Neurological Examination
Brachial Gunshot Wounds: Injury Patterns and Considerations for Managing the Abnormal Neurological Examination Open
Background: Nerve injuries from gunshot wounds (GSWs) to the upper arm can cause significant morbidity and loss of function. However, indications for surgical exploration and nerve reconstruction remain unclear as both low- and high-grade …
View article: The Medial Antebrachial Cutaneous Nerve Is a Low-Morbidity Alternative to the Standard Sural Nerve Autograft
The Medial Antebrachial Cutaneous Nerve Is a Low-Morbidity Alternative to the Standard Sural Nerve Autograft Open
Background: Nerve interposition grafting is an important technique in nerve reconstructive surgery that is used when a primary repair is not feasible without significant tension. This study sought to evaluate the long-term morbidity of the…
View article: Limited recovery following acellular nerve allograft reconstruction in major peripheral nerve injuries
Limited recovery following acellular nerve allograft reconstruction in major peripheral nerve injuries Open
Recent studies suggest that acellular nerve allografts (ANA) have similar efficacy as nerve autografts in certain applications of nerve surgery. However, multiple studies also demonstrate the limitations of nerve allografts, resulting in p…
View article: Therapeutic strategies for peripheral nerve injuries: FK506 and electrostimulation
Therapeutic strategies for peripheral nerve injuries: FK506 and electrostimulation Open
Efficacious therapeutics for peripheral nerve injuries remain incompletely described in the literature. However, over the last several decades, delivery of FK506 (Tacrolimus) and electrostimulation have demonstrated great promise for suppl…
View article: Therapeutic strategies for peripheral nerve injuries: FK506 and electrostimulation
Therapeutic strategies for peripheral nerve injuries: FK506 and electrostimulation Open
Efficacious therapeutics for peripheral nerve injuries remain incompletely described in the literature. However, over the last several decades, delivery of FK506 (Tacrolimus) and electrostimulation have demonstrated great promise for suppl…
View article: A feasibility study transplanting macrophages to a segmental nerve injury
A feasibility study transplanting macrophages to a segmental nerve injury Open
Introduction/Aims Promoting regeneration after segmental nerve injury repair is a challenge, but improving angiogenesis could be beneficial. Macrophages facilitate regeneration after injury by promoting angiogenesis. Our aim in this study …
View article: Improving the Care of Our Patients
Improving the Care of Our Patients Open
Background James Barrett Brown was one of the founders of Plastic and Reconstructive Surgery as a specialty in the United States. Susan Mackinnon started the James Barrett Brown Resident Research Day in 1997 in his honor to serve as an ann…
View article: SP04. Abductor Digiti Minimi Turbocharged End-to-side Nerve Transfer is a Novel Technique to Restore Ulnar Motor Function
SP04. Abductor Digiti Minimi Turbocharged End-to-side Nerve Transfer is a Novel Technique to Restore Ulnar Motor Function Open
PURPOSE: Supercharged end-to-side (SETS) anterior interosseous nerve transfer (AIN) to reinnervate the ulnar intrinsic musculature is an increasingly accepted mode of treatment following ulnar nerve injury. However, results can remain subo…
View article: Increasing Awareness of Complications of Nerve Injury Following Shoulder Surgery: Preventing Delays in Referral and Treatment
Increasing Awareness of Complications of Nerve Injury Following Shoulder Surgery: Preventing Delays in Referral and Treatment Open
Background: Nerve injuries remain a challenging complication after shoulder surgery. While most resolve spontaneously, some require surgical intervention. This study describes the characteristics of patients sustaining nerve injuries follo…
View article: At the Interface of Atrocity, Art, and Anatomy: A Review of Eduard Pernkopf’s Atlas of Topographical and Applied Human Anatomy in Surgical Anatomy and Medical Ethics
At the Interface of Atrocity, Art, and Anatomy: A Review of Eduard Pernkopf’s Atlas of Topographical and Applied Human Anatomy in Surgical Anatomy and Medical Ethics Open
PURPOSE: The use of Eduard Pernkopf's Atlas of Topographical and Applied Human Anatomy in operating rooms is an enduring subject of ethical debate. Disturbing details around the atlas' Nazi origins create enormous moral and ethical tension…
View article: Posterior Interosseous Nerve Compression in the Forearm, AKA Radial Tunnel Syndrome: A Clinical Diagnosis
Posterior Interosseous Nerve Compression in the Forearm, AKA Radial Tunnel Syndrome: A Clinical Diagnosis Open
Background: Posterior interosseous nerve (PIN) compression in the forearm without motor paralysis is a challenging clinical diagnosis. This retrospective study evaluated the clinical assessment, diagnostic studies, and outcomes following s…
View article: 134. Dispose With Dish Soap: A Simple And Convenient Method to Increase Proper Opioid Disposal in Postoperative Pediatric Patients
134. Dispose With Dish Soap: A Simple And Convenient Method to Increase Proper Opioid Disposal in Postoperative Pediatric Patients Open
Purpose: The opioid abuse crisis is rampant in the United States. Overprescribing patterns and lack of patient education regarding safe opioid use and disposal have contributed to misuse, dependence, and diversion. Children and adolescents…
View article: 39. NERVE TRANSFERS CAN IMPROVE UPPER EXTREMITY FUNCTION IN CERVICAL SPINAL CORD INJURY: A PROSPECTIVE PROOF-OF-CONCEPT STUDY
39. NERVE TRANSFERS CAN IMPROVE UPPER EXTREMITY FUNCTION IN CERVICAL SPINAL CORD INJURY: A PROSPECTIVE PROOF-OF-CONCEPT STUDY Open
PURPOSE: Restoration of upper extremity (UE) function is important to people living with cervical spinal cord injury (SCI) and nerve transfer surgery (NT) is poised to change the treatment paradigm. In this proof-of-concept study, we hypot…
View article: Revision of Carpal Tunnel Surgery
Revision of Carpal Tunnel Surgery Open
Carpal tunnel release is one of the most commonly performed upper extremity procedures. The majority of patients experience significant improvement or resolution of their symptoms. However, a small but important subset of patients will exp…
View article: Nerve Surgeons’ Assessment of the Role of Eduard Pernkopf ’s Atlas of Topographic and Applied Human Anatomy in Surgical Practice
Nerve Surgeons’ Assessment of the Role of Eduard Pernkopf ’s Atlas of Topographic and Applied Human Anatomy in Surgical Practice Open
Pernkopf's Atlas of Anatomy contains anatomical plates with detailed images of the peripheral nerves. Its use is controversial due to the author's association with the "Third Reich" and the potential depiction of victims of the Holocaust. …
View article: Before and After I Knew: Disclosure, Respect, Gratitude, and Solemnity
Before and After I Knew: Disclosure, Respect, Gratitude, and Solemnity Open
The Pernkopf anatomical atlas has contributed significantly to the specialty of nerve surgery through its infiltration in surgical training and the development of novel procedures due to the accurate depiction of the nervous system. Until …