Susan E. Sharp
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View article: Does the addition of fentanyl premedication impact brown fat uptake in children undergoing a warming protocol for FDG PET?
Does the addition of fentanyl premedication impact brown fat uptake in children undergoing a warming protocol for FDG PET? Open
Background Fentanyl is used in some pediatric practices with a goal of suppressing 18F-fluorodeoxyglucose (18F-FDG) uptake in brown fat. Objective The purpose of this study was to examine the frequency, intensity, and distribution of brown…
View article: Impact of upgrading from a 25-cm to a 30-cm z-axis field of view digital PET/CT in a pediatric hospital
Impact of upgrading from a 25-cm to a 30-cm z-axis field of view digital PET/CT in a pediatric hospital Open
Background Increased positron emission tomography (PET) scanner z -axis coverage provides an opportunity in pediatrics to reduce dose, anesthesia, or repeat scans due to motion. Objective Recently, our digital PET scanner was upgraded from…
View article: Proceedings of the Clinical Microbiology Open 2022—assessing clinical laboratory and industry responses to COVID-19 pandemic testing capacity challenges (part 1)
Proceedings of the Clinical Microbiology Open 2022—assessing clinical laboratory and industry responses to COVID-19 pandemic testing capacity challenges (part 1) Open
As the COVID-19 pandemic winds down, clinical and public health laboratories, along with industry partners, reflect on the successes and failures of the pandemic response. To capture the lessons learned and better prepare for the next pand…
View article: Dabrafenib and trametinib in Langerhans cell histiocytosis and other histiocytic disorders
Dabrafenib and trametinib in Langerhans cell histiocytosis and other histiocytic disorders Open
Standard treatment for Langerhans Cell Histiocytosis (LCH) is chemotherapy, with high failure rates. Since MAP-kinase activating mutations are found in most cases, BRAF- and MEKinhibitors have been used successfully to treat patients with …
View article: Imaging of pediatric bone tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper
Imaging of pediatric bone tumors: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper Open
Malignant primary bone tumors are uncommon in the pediatric population, accounting for 3%–5% of all pediatric malignancies. Osteosarcoma and Ewing sarcoma comprise 90% of malignant primary bone tumors in children and adolescents. This pape…
View article: Imaging of pediatric neuroblastoma: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper
Imaging of pediatric neuroblastoma: A COG Diagnostic Imaging Committee/SPR Oncology Committee White Paper Open
Neuroblastoma is the most common extracranial solid neoplasm in children. This manuscript provides consensus‐based imaging recommendations for pediatric neuroblastoma patients at diagnosis and during follow‐up.
View article: Clinical Laboratory Perspective on <i>Streptococcus halichoeri</i>, an Unusual Nonhemolytic, Lancefield Group B Streptococcus Causing Human Infections
Clinical Laboratory Perspective on <i>Streptococcus halichoeri</i>, an Unusual Nonhemolytic, Lancefield Group B Streptococcus Causing Human Infections Open
Streptococcus halichoeri is a relatively newly identified species of pyogenic streptococci that causes zoonotic infection in humans. S. halichoeri was first described in 2004 as indigenous to seals, and only 8 reports of human S. halichoer…
View article: Clinical Laboratory Perspective on <i>Streptococcus halichoeri</i>, an Unusual Nonhemolytic, Lancefield Group B Streptococcus Causing Human Infections
Clinical Laboratory Perspective on <i>Streptococcus halichoeri</i>, an Unusual Nonhemolytic, Lancefield Group B Streptococcus Causing Human Infections Open
Streptococcus halichoeri is a relatively newly identified species of pyogenic streptococci that causes zoonotic infection in humans. S. halichoeri was first described in 2004 as indigenous to seals, and only 8 reports of human S. halichoer…
View article: Expert Opinion on Verification of Antimicrobial Susceptibility Tests
Expert Opinion on Verification of Antimicrobial Susceptibility Tests Open
On behalf of the Clinical and Laboratory Standards Institute (CLSI), the Expert Panel on Microbiology would like to respond to the recent commentary by Kirby and colleagues voicing concerns related to the verification of commercial antimic…
View article: College of American Pathologists (CAP) Microbiology Committee Perspective: the Need for Verification Studies
College of American Pathologists (CAP) Microbiology Committee Perspective: the Need for Verification Studies Open
On behalf of the Microbiology Committee of the College of American Pathologists (CAP), we respond to the recent commentary by Kirby and colleagues on the topic of bringing in new antimicrobial susceptibility testing (1). The authors state …
View article: Reply from Kirn and Sharp to Brecher, ‘EUCAST and CLSI Point-Counterpoint on Susceptibility Breakpoints: Do Two “I Agree”s Miss the Point?’
Reply from Kirn and Sharp to Brecher, ‘EUCAST and CLSI Point-Counterpoint on Susceptibility Breakpoints: Do Two “I Agree”s Miss the Point?’ Open
U ndoubtedly, complete harmonization of antimicrobial susceptibility breakpoints and categorical interpretations worldwide would mean less confusion for laboratorians and doctors and would also simplify global surveillance efforts that rel…
View article: Point-Counterpoint: Differences between the European Committee on Antimicrobial Susceptibility Testing and Clinical and Laboratory Standards Institute Recommendations for Reporting Antimicrobial Susceptibility Results
Point-Counterpoint: Differences between the European Committee on Antimicrobial Susceptibility Testing and Clinical and Laboratory Standards Institute Recommendations for Reporting Antimicrobial Susceptibility Results Open
Antibiotic susceptibility test results are among the most important results issued by clinical microbiology laboratories because they routinely guide critical treatment decisions. Interpretations of MIC or disk diffusion test results, such…
View article: SPR 2018
SPR 2018 Open
Imaging technologists are integral to our work.I am very pleased that, for the third year, there will be a Pediatric Imaging Technologists' Course, renamed from "Radiographers' Course to reflect its broader content.The course is again orga…
View article: Detection of lymph node metastases in pediatric and adolescent/young adult sarcoma: Sentinel lymph node biopsy versus fludeoxyglucose positron emission tomography imaging—A prospective trial
Detection of lymph node metastases in pediatric and adolescent/young adult sarcoma: Sentinel lymph node biopsy versus fludeoxyglucose positron emission tomography imaging—A prospective trial Open
BACKGROUND Lymph node metastases are an important cause of treatment failure for pediatric and adolescent/young adult (AYA) sarcoma patients. Nodal sampling is recommended for certain sarcoma subtypes that have a predilection for lymphatic…
View article: Commentary: Individualized Quality Control Plan (IQCP): Is It Value-Added for Clinical Microbiology?
Commentary: Individualized Quality Control Plan (IQCP): Is It Value-Added for Clinical Microbiology? Open
The Center for Medicaid and Medicare Services (CMS) recently published their Individualized Quality Control Plan (IQCP [ https://www.cms.gov/regulations-and-guidance/legislation/CLIA/Individualized_Quality_Control_Plan_IQCP.html ]), which …
View article: Answer to August 2015 Photo Quiz
Answer to August 2015 Photo Quiz Open
Answer: Borrelia species causing recurrent fever. Borrelia is a Gram-negative bacterium (0.2 to 0.5 μm by 5 to 20 μm) which causes tick-borne relapsing fever (TBRF) and louse-borne relapsing fever. Symptoms consist of recurring episodes of…
View article: Photo Quiz: High Fevers in the High Desert in Oregon
Photo Quiz: High Fevers in the High Desert in Oregon Open
A patient's wife called the Kaiser Permanente clinic and spoke to the advice registered nurse (RN) on behalf of her wife (the 56-year-old patient declined to come to the phone). The patient's wife stated that the patient had persistent fev…