Susan J. Diem
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View article: Addressing omission bias in the treatment of osteoporosis: evidence from a cross-sectional study and a randomized experiment
Addressing omission bias in the treatment of osteoporosis: evidence from a cross-sectional study and a randomized experiment Open
Findings elucidate the role of decision making biases in the treatment of osteoporosis and highlight the need for further intervention work in this area.
View article: Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study
Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study Open
View article: Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study
Correction to: Comparison of fracture risk assessment tools in older men without prior hip or spine fracture: the MrOS study Open
View article: Complementary and Alternative Therapies for Genitourinary Syndrome of Menopause
Complementary and Alternative Therapies for Genitourinary Syndrome of Menopause Open
Agency for Healthcare Research and Quality and Patient-Centered Outcomes Research Institute. (PROSPERO: CRD42023400684).
View article: Hormonal Treatments and Vaginal Moisturizers for Genitourinary Syndrome of Menopause
Hormonal Treatments and Vaginal Moisturizers for Genitourinary Syndrome of Menopause Open
Agency for Healthcare Research and Quality and Patient-Centered Outcomes Research Institute. (PROSPERO: CRD42023400684).
View article: Reimagining How We Synthesize Information to Impact Clinical Care, Policy, and Research Priorities in Real Time: Examples and Lessons Learned from COVID-19
Reimagining How We Synthesize Information to Impact Clinical Care, Policy, and Research Priorities in Real Time: Examples and Lessons Learned from COVID-19 Open
View article: American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation
American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation Open
INTRODUCTION: Chronic idiopathic constipation (CIC) is a common disorder associated with significant impairment in quality of life. This clinical practice guideline, jointly developed by the American Gastroenterological Association and the…
View article: American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation
American Gastroenterological Association-American College of Gastroenterology Clinical Practice Guideline: Pharmacological Management of Chronic Idiopathic Constipation Open
View article: Drive Time and Receipt of Guideline-Recommended Screening, Diagnosis, and Treatment
Drive Time and Receipt of Guideline-Recommended Screening, Diagnosis, and Treatment Open
Importance Many patients do not receive recommended services. Drive time to health care services may affect receipt of guideline-recommended care, but this has not been comprehensively studied. Objective To assess associations between driv…
View article: COVID-19 postacute care major organ damage: a systematic review
COVID-19 postacute care major organ damage: a systematic review Open
Background Major organ complications have been reported in patients hospitalised for COVID-19; most studies lacked controls. Objective Examine major organ damage postdischarge among adults hospitalised for COVID-19 versus non-COVID-19 cont…
View article: Lower Leg Power and Grip Strength Are Associated With Increased Fall Injury Risk in Older Men: The Osteoporotic Fractures in Men Study
Lower Leg Power and Grip Strength Are Associated With Increased Fall Injury Risk in Older Men: The Osteoporotic Fractures in Men Study Open
Background Past research has not investigated both lower-extremity power and upper-extremity strength in the same fall injury study, particularly nonfracture fall injuries. Methods In the Osteoporotic Fractures in Men Study (baseline: N = …
View article: Are serum estrogen concentrations associated with menopausal symptom bother among postmenopausal women? Baseline results from two MsFLASH clinical trials
Are serum estrogen concentrations associated with menopausal symptom bother among postmenopausal women? Baseline results from two MsFLASH clinical trials Open
These findings do not support the clinical utility of a single measurement of serum of E1, E2, or SHBG concentrations in differentiating between women who are bothered by a given menopausal symptom and those who are n…
View article: Care Coordination Models and Tools—Systematic Review and Key Informant Interviews
Care Coordination Models and Tools—Systematic Review and Key Informant Interviews Open
View article: <scp>Life‐space</scp> mobility and healthcare costs and utilization in older men
<span>Life‐space</span> mobility and healthcare costs and utilization in older men Open
Objectives To determine the association of life‐space score with subsequent healthcare costs and utilization. Design Prospective cohort study (Osteoporotic Fracture in Men [MrOS]). Setting Six U.S. sites. Participants A total of 1555 commu…
View article: Effects of pharmacologic and nonpharmacologic interventions on menopause-related quality of life: a pooled analysis of individual participant data from four MsFLASH trials
Effects of pharmacologic and nonpharmacologic interventions on menopause-related quality of life: a pooled analysis of individual participant data from four MsFLASH trials Open
Objective: The Menopause Strategies: Finding Lasting Answers for Symptoms and Health network conducted three randomized clinical trials (RCTs) testing six interventions treating vasomotor symptoms (VMS), and also collected menopause-relate…
View article: Table of Contents
Table of Contents Open
View article: Association between post-stroke disability and 5-year hip-fracture risk: The Women's Health Initiative
Association between post-stroke disability and 5-year hip-fracture risk: The Women's Health Initiative Open
View article: Time to Osteoporosis and Major Fracture in Older Men
Time to Osteoporosis and Major Fracture in Older Men Open
For older men who undergo bone mineral density (BMD) testing, the optimal osteoporosis screening schedule is unknown. Time-to-disease estimates are necessary to inform screening intervals.
View article: Lights on MsFLASH: a review of contributions
Lights on MsFLASH: a review of contributions Open
Objective: The Menopause Strategies: Finding Lasting Answers for Symptoms and Health clinical trials network was funded by the National Institutes of Health to find new ways to alleviate the most common, bothersome menopausal symptoms by d…
View article: Patient-centered change in the day-to-day impact of postmenopausal vaginal symptoms: results from a multicenter randomized trial
Patient-centered change in the day-to-day impact of postmenopausal vaginal symptoms: results from a multicenter randomized trial Open
View article: Convergent-Divergent Validity and Correlates of the Day-to-Day Impact of Vaginal Aging Domain Scales in the MsFLASH Vaginal Health Trial
Convergent-Divergent Validity and Correlates of the Day-to-Day Impact of Vaginal Aging Domain Scales in the MsFLASH Vaginal Health Trial Open
Introduction Clinical research and management of postmenopausal vaginal symptoms have been limited by the lack of validated measures for assessing symptom impact. Aim To evaluate convergent-divergent validity of the Day-to-Day Impact of Va…
View article: Association of Anticoagulant Therapy With Risk of Fracture Among Patients With Atrial Fibrillation
Association of Anticoagulant Therapy With Risk of Fracture Among Patients With Atrial Fibrillation Open
In this real-world population of 167 275 patients with AF, use of DOACs-particularly apixaban-compared with warfarin use was associated with lower fracture risk. These associations were more pronounced among patients with a diagnosis of os…
View article: Prostate-Specific Antigen Levels During Testosterone Treatment of Hypogonadal Older Men: Data from a Controlled Trial
Prostate-Specific Antigen Levels During Testosterone Treatment of Hypogonadal Older Men: Data from a Controlled Trial Open
Context Prostate-specific antigen (PSA) changes during testosterone treatment of older hypogonadal men have not been rigorously evaluated. Design Double-blinded, placebo-controlled trial. Setting Twelve US academic medical centers. Partici…
View article: Association of Disease Definition, Comorbidity Burden, and Prognosis With Hip Fracture Probability Among Late-Life Women
Association of Disease Definition, Comorbidity Burden, and Prognosis With Hip Fracture Probability Among Late-Life Women Open
Women 80 years and older who have osteoporosis, including those with more comorbidities or poorer prognosis, have a high 5-year probability of hip fracture despite accounting for competing mortality risk. In contrast, among women without o…
View article: Facebook advertising for recruitment of midlife women with bothersome vaginal symptoms: A pilot study
Facebook advertising for recruitment of midlife women with bothersome vaginal symptoms: A pilot study Open
Background The MsFLASH (Menopause Strategies: Finding Lasting Answers for Symptoms and Health) Network recruited into five randomized clinical trials (n = 100–350) through mass mailings. The fifth trial tested two interventions for postmen…
View article: Sexual frequency and pain in a randomized clinical trial of vaginal estradiol tablets, moisturizer, and placebo in postmenopausal women
Sexual frequency and pain in a randomized clinical trial of vaginal estradiol tablets, moisturizer, and placebo in postmenopausal women Open
Objective: To evaluate the efficacy of two common interventions for bothersome postmenopausal vaginal symptoms on improving sexual frequency and pain. Methods: This is a post-hoc analysis of data from a 12-week double-blind placebo-control…
View article: Depressive Symptoms and Total Healthcare Costs: Roles of Functional Limitations and Multimorbidity
Depressive Symptoms and Total Healthcare Costs: Roles of Functional Limitations and Multimorbidity Open
OBJECTIVES Depressive symptoms can be both a cause and a consequence of functional limitations and medical conditions. Our objectives were to determine the association of depressive symptoms with subsequent total healthcare costs in older …
View article: IMPACT OF COMORBIDITY AND PROGNOSIS ON HIP FRACTURE AND MORTALITY INCIDENCE AMONG WOMEN IN LATE LIFE
IMPACT OF COMORBIDITY AND PROGNOSIS ON HIP FRACTURE AND MORTALITY INCIDENCE AMONG WOMEN IN LATE LIFE Open
Concerns about comorbidities and limited life expectancy increase the complexity of managing osteoporosis in late life. To determine effects of comorbidity burden and prognostic information on cumulative incidence of hip fracture among ost…
View article: ASSOCIATION OF DEPRESSIVE SYMPTOMS WITH TOTAL HEALTH CARE COSTS IN OLDER WOMEN
ASSOCIATION OF DEPRESSIVE SYMPTOMS WITH TOTAL HEALTH CARE COSTS IN OLDER WOMEN Open
Whether or not depressive symptoms predict total health care costs (THC) independent of both multimorbidity and functional impairment is unclear. In a prospective cohort of 2510 women (mean age 80.2 years) linked with Medicare claims, we e…
View article: Effects of vaginal estradiol tablets and moisturizer on menopause-specific quality of life and mood in healthy postmenopausal women with vaginal symptoms: a randomized clinical trial
Effects of vaginal estradiol tablets and moisturizer on menopause-specific quality of life and mood in healthy postmenopausal women with vaginal symptoms: a randomized clinical trial Open
Objective: Compare the effects of a vaginal estradiol tablet and a vaginal moisturizer, each to placebo, on menopause-related quality of life and mood in postmenopausal women with moderate–severe vulvovaginal symptoms. Methods: A total of …