Susan J. Maygarden
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View article: Less Is More: Evaluation of Gross Examination Protocol for Cystectomy Specimens Following Neoadjuvant Chemotherapy
Less Is More: Evaluation of Gross Examination Protocol for Cystectomy Specimens Following Neoadjuvant Chemotherapy Open
Objectives Neoadjuvant chemotherapy (NAC) confers a survival advantage for muscle-invasive bladder cancer and is now recommended for chemotherapy-eligible patients. NAC may result in absent gross tumor, and current cystectomy gross examina…
View article: Neoadjuvant pazopanib and molecular analysis of tissue response in renal cell carcinoma
Neoadjuvant pazopanib and molecular analysis of tissue response in renal cell carcinoma Open
BACKGROUNDSurgery remains the frontline therapy for patients with localized clear cell renal cell carcinoma (ccRCC); however, 20%-40% recur. Angiogenesis inhibitors have improved survival in metastatic patients and may result in responses …
View article: Comparison of ACINUS, caspase-3, and TUNEL as apoptotic markers in determination of tumor growth rates of clinically localized prostate cancer using image analysis
Comparison of ACINUS, caspase-3, and TUNEL as apoptotic markers in determination of tumor growth rates of clinically localized prostate cancer using image analysis Open
The balance between apoptotic and proliferative processes determines the enlargement of a tumor. Accurate measurement of apoptotic and proliferative rates from diagnostic prostate biopsies would allow calculation of tumor growth rates in a…
View article: Establishment of Short-Term Primary Human Prostate Xenografts for the Study of Prostate Biology and Cancer
Establishment of Short-Term Primary Human Prostate Xenografts for the Study of Prostate Biology and Cancer Open
Human tissue xenograft models are currently the only tool for conducting in vivo analyses of intact human tissue. The goal of the present study was to develop reliable methods for successful generation of short-term primary tissue xenograf…
View article: Viral Response to Chemotherapy in Endemic Burkitt Lymphoma
Viral Response to Chemotherapy in Endemic Burkitt Lymphoma Open
Some Epstein-Barr virus (EBV)-directed therapies are predicted to be effective only when lytic viral replication occurs. We studied whether cyclophosphamide chemotherapy induces EBV to switch from latent to lytic phases of infection in a s…
View article: Opinions and Practices of Lung Cancer Screening by Physician Specialty
Opinions and Practices of Lung Cancer Screening by Physician Specialty Open
BACKGROUND In response to the National Lung Screening Trial, numerous professional organizations published guidelines recommending annual lung cancer screening with low-dose computed tomography (LDCT) for high-risk patients. Prior studies …
View article: Phase II trial of palbociclib in patients with metastatic urothelial cancer after failure of first-line chemotherapy
Phase II trial of palbociclib in patients with metastatic urothelial cancer after failure of first-line chemotherapy Open
Palbociclib did not demonstrate meaningful activity in selected patients with platinum-refractory metastatic UC. Further development of palbociclib should only be considered with improved integral biomarker selection or in rational combina…
View article: Issue Information
Issue Information Open
The use of the equivocal and elusive diagnosis of "atypia" in our daily practice cannot be completely eliminated as it continues to be a useful category for filling the gap between what is recognizable as normal (or at least a version of n…
View article: Northern Italy in the American South: Assessing interobserver reliability within the Milan System for Reporting Salivary Gland Cytopathology
Northern Italy in the American South: Assessing interobserver reliability within the Milan System for Reporting Salivary Gland Cytopathology Open
BACKGROUND The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) has been proposed to standardize salivary gland fine‐needle aspiration (FNA) diagnoses. This study assessed salivary gland FNA results and risk of malignancy (…