Explanipedia

Hair Cortisone Levels and the Metabolic Syndrome: Stronger Links in Younger Compared to Older Adults Open

Susanne Kuckuck, Robin Lengton, Julius März, Nina van Gerwen, Dimitris Rizopoulos , et al. · 2025

Background The striking link between Cushing syndrome, the metabolic syndrome (MetS), and cardiovascular disease suggests that long-term exposure to high glucocorticoid levels catalyzes cardiometabolic deterioration. However, the relation …

Alterations of appetite‐regulating hormones in risperidone treated children and adolescents—a post hoc analysis of the SPACe study Open

Jiayi Liang, Brenda C. M. de Winter, Rebecca A. Hermans, Sanne Kloosterboer, Susanne Kuckuck , et al. · 2025

Weight gain and metabolic disruptions are common in children and adolescents treated with antipsychotics, but the underlying mechanisms are unclear, complicating prevention and treatment. This study examines the impact of risperidone on ap…

Long-term hair cortisone and perceived stress are associated with long-term hedonic eating tendencies in patients with obesity Open

Susanne Kuckuck, Eline S. van der Valk, Robin Lengton, Julius März, Manon H. J. Hillegers , et al. · 2024

Long-term psychological and biological stress correlate with hedonic eating tendencies with potentially adverse additive effects on weight management and clinical features of obesity.

Perceived Stress, Hair Cortisol, and Hair Cortisone in Relation to Appetite-Regulating Hormones in Patients with Obesity Open

Susanne Kuckuck, Robin Lengton, Renate E H Meeusen, Eline S. van der Valk, Manon H. J. Hillegers , et al. · 2024

Introduction: Stress predicts unhealthy eating, obesity, and metabolic deterioration, likely mediated by altered levels of appetite-regulating hormones. Yet, evidence regarding the association between long-term stress and levels of appetit…

Neighborhood Characteristics Related to Changes in Anthropometrics During a Lifestyle Intervention for Persons with Obesity Open

B Brouwer, Susanne Kuckuck, Renate E. H. Meeusen, Mostafa Mohseni, Robin Lengton , et al. · 2024

Background Since obesity has emerged as a major public health concern, there is an urgent need to better understand factors related to weight gain and treatment success. Methods This study included 118 persons with obesity who participated…

Long-Term Glucocorticoid Exposure and Incident Cardiovascular Diseases—The Lifelines Cohort Open

Eline S. van der Valk, Mostafa Mohseni, Anand M. Iyer, Maartje J. B. Van den Hurk, Robin Lengton , et al. · 2024

Context Long-term glucocorticoid levels in scalp hair (HairGCs), including cortisol and the inactive form cortisone, represent the cumulative systemic exposure to glucocorticoids over months. HairGCs have repeatedly shown associations with…

Long‐term glucocorticoids in relation to the metabolic syndrome and cardiovascular disease: A systematic review and meta‐analysis Open

Susanne Kuckuck, Robin Lengton, Mariëtte R. Boon, Eric Boersma, Brenda W.J.H. Penninx , et al. · 2023

The striking link of Cushing's syndrome with the metabolic syndrome (MetS) and cardiovascular disease (CVD) suggests that long‐term exposure to extremely high cortisol levels catalyzes cardiometabolic deterioration. However, it remained un…

Determination of cortisone and cortisol in human scalp hair using an improved LC-MS/MS-based method Open

Mina Mirzaian, Sofie K M van Zundert, Wim F. Schilleman, Mostafa Mohseni, Susanne Kuckuck , et al. · 2023

Objectives Human scalp hair is an easily available but complex matrix for determination of cortisone and cortisol, and has been shown to reflect long-term glucocorticoid exposure. Hair glucocorticoid analysis has been used to detect hypo- …

Levels of hormones regulating appetite and energy homeostasis in response to a 1.5-Year combined lifestyle intervention for obesity Open

Susanne Kuckuck, Eline S. van der Valk, A.J.W. Scheurink, Robin Lengton, Mostafa Mohseni , et al. · 2023

Background: Weight loss can induce changes in appetite-regulating hormone levels, possibly linked to increases in appetite and weight regain. However, hormonal changes vary across interventions. Here, we studied levels of appetite-regulati…

Supplementary data to article "Long-term glucocorticoid exposure and incident cardiovascular diseases – the Lifelines cohort" Open

Eline S. van der Valk, Mostafa Mohseni, Anand M. Iyer, Maartje van den Hurk, Robin Lengton , et al. · 2023

Supplementary data to the article "Long-term glucocorticoid exposure and incident cardiovascular diseases – the Lifelines cohort".

Improved Physical and Mental Health After a Combined Lifestyle Intervention with Cognitive Behavioural Therapy for Obesity Open

Mostafa Mohseni, Susanne Kuckuck, Renate E. H. Meeusen, Geranne Jiskoot, Robin Lengton , et al. · 2022

Background: Obesity is a multifactorial, chronic, progressive disease associated with decreased health-related quality of life, comorbidities, and increased mortality risk. Lifestyle interventions, focusing on dietetics, physical exercise,…

Glucocorticoids, stress and eating: The mediating role of appetite‐regulating hormones Open

Susanne Kuckuck, Eline S. van der Valk, A.J.W. Scheurink, Bibian van der Voorn, Anand M. Iyer , et al. · 2022

Summary Disrupted hormonal appetite signaling plays a crucial role in obesity as it may lead to uncontrolled reward‐related eating. Such disturbances can be induced not only by weight gain itself but also by glucocorticoid overexposure, fo…

Improvements in Long-Term Appetite-Regulating Hormones in Response to a Combined Lifestyle Intervention for Obesity Open

Susanne Kuckuck · 2021

Altered levels of hormonal appetite regulators have been observed in obesity (BMI ≥ 30.0 kg/m2), most prominently increases of insulin and leptin (indicating resistance) as well as decreases of adiponectin - all of which are long-term ener…

Susanne Kuckuck YOU? Author Swipe