Susheel Pangeni
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View article: Comprehensive analysis of the role of <i>ASC1</i> and <i>APE2</i> introns on cellular fitness, transcription, and post‐transcriptional dynamics
Comprehensive analysis of the role of <i>ASC1</i> and <i>APE2</i> introns on cellular fitness, transcription, and post‐transcriptional dynamics Open
A splicing‐competent intron has been found to affect the expression of a gene at almost every step between transcription and translation. In this investigation, we performed a comprehensive analysis of the role of an intron from two yeast …
View article: Molecular Modeling of ABHD5 Structure and Ligand Recognition
Molecular Modeling of ABHD5 Structure and Ligand Recognition Open
Alpha/beta hydrolase domain-containing 5 (ABHD5), also termed CGI-58, is the key upstream activator of adipose triglyceride lipase (ATGL), which plays an essential role in lipid metabolism and energy storage. Mutations in ABHD5 disrupt lip…