Suxia Lin
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View article: Deep learning algorithms for identifying developmental dysplasia of the hip based on sonographic images: a retrospective, prospective, multicenter study in China
Deep learning algorithms for identifying developmental dysplasia of the hip based on sonographic images: a retrospective, prospective, multicenter study in China Open
1. Guangdong High-level Hospital Construction Fund (SZGSP012), 2. Shenzhen Clinical Research Center (20220819113341005) "Shenzhen Clinical Research Center for Child Health and Disease (szcrc2024_005)", 3. Guangdong Medical Research Funded …
View article: Magnetic Resonance Imaging and [<scp>18F</scp>]‐Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography‐Guided Therapy Improves Survival in Upper Aerodigestive Tract <scp>NK</scp>/T‐Cell Lymphoma, Nasal Type: A Prospective Cohort Study
Magnetic Resonance Imaging and [<span>18F</span>]‐Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography‐Guided Therapy Improves Survival in Upper Aerodigestive Tract <span>NK</span>/T‐Cell Lymphoma, Nasal Type: A Prospective Cohort Study Open
Background To investigate the value of pretreatment nasopharyngeal and neck magnetic resonance imaging (NN‐MRI) combined with positron emission tomography (PET)/CT‐guided therapy for improving survival in upper aerodigestive tract NK/T‐cel…
View article: Primary intestinal diffuse large B-cell lymphoma: novel insights and clinical perception
Primary intestinal diffuse large B-cell lymphoma: novel insights and clinical perception Open
Background Extranodal Non-Hodgkin lymphoma (NHL) is more prevalent in the gastrointestinal (GI) tract than in other sites. This study aimed to explore the clinical features and prognostic factors of primary intestinal diffuse large B-cell …
View article: Angioimmunoblastic T-cell lymphoma involving the nasopharynx: An easily misdiagnosed disease with atypical histopathological features
Angioimmunoblastic T-cell lymphoma involving the nasopharynx: An easily misdiagnosed disease with atypical histopathological features Open
Nasopharyngeal involvement is common in AITL but can be easily misdiagnosed because of its atypical pathologic pattern, especially when a lymph node biopsy is unavailable. However, the patient's clinical presentation, PET/CT manifestations…
View article: P1140: COMBINATION ANTI-PD1 ANTIBODY AND RITUXIMAB FOLLOWED BY R-CHOP FOR NEWLY DIAGNOSED DLBCL IN ELDERLY PATIENTS: ANALYSIS OF THE PHASE II TREND TRIAL
P1140: COMBINATION ANTI-PD1 ANTIBODY AND RITUXIMAB FOLLOWED BY R-CHOP FOR NEWLY DIAGNOSED DLBCL IN ELDERLY PATIENTS: ANALYSIS OF THE PHASE II TREND TRIAL Open
Topic: 19. Aggressive Non-Hodgkin lymphoma - Clinical Background: Patients with diffuse large B-cell lymphoma (DLBCL) in the elderly face challenges in treatment due to comorbidities and tolerance of chemotherapy. Besides, increased propor…
View article: Multifunctional Mesoporous Silica-Coated Gold Nanorods Mediate Mild Photothermal Heating-Enhanced Gene/Immunotherapy for Colorectal Cancer
Multifunctional Mesoporous Silica-Coated Gold Nanorods Mediate Mild Photothermal Heating-Enhanced Gene/Immunotherapy for Colorectal Cancer Open
Colorectal cancer (CRC) is the third most common cancer worldwide and the second leading cause of cancer-related deaths in the world. It is urgent to search for safe and effective therapies to address the CRC crisis. The siRNA-based RNA in…
View article: Targeting TET2 as a Therapeutic Approach for Angioimmunoblastic T Cell Lymphoma
Targeting TET2 as a Therapeutic Approach for Angioimmunoblastic T Cell Lymphoma Open
Angioimmunoblastic T-cell lymphoma (AITL), a type of malignant lymphoma with unique genomic aberrations, significant clinicopathological features, and poor prognosis, is characterized by immune system dysregulation. Recent sequencing studi…
View article: Thymic Extranodal Marginal-Zone Lymphoma of Mucosa-Associated Lymphoid Tissue: Pathological Features, 18F-FDG PET/CT Findings and Prognosis in 12 Cases
Thymic Extranodal Marginal-Zone Lymphoma of Mucosa-Associated Lymphoid Tissue: Pathological Features, 18F-FDG PET/CT Findings and Prognosis in 12 Cases Open
Purpose Primary thymic extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) lymphoma is a rare type of MALT lymphoma. We aim to investigate the clinicopathologic features, 18 F-FDG PET/CT findings and outcomes for …
View article: Mesoporous silica-coated silver nanoparticles as ciprofloxacin and siRNA co-delivery multifunctional platform for accelerated infected wound healing
Mesoporous silica-coated silver nanoparticles as ciprofloxacin and siRNA co-delivery multifunctional platform for accelerated infected wound healing Open
The colonization of bacterial pathogens is a major concern in wound infection and becoming a public health issue. Herein, a core-shell structured Ag@MSN (silver core embedded with mesoporous silica, AM)-based nanoplatform was elaborately f…
View article: A novel prognostic nomogram for patients with extragastric mucosa‐associated lymphoid tissue lymphoma: A multicenter study
A novel prognostic nomogram for patients with extragastric mucosa‐associated lymphoid tissue lymphoma: A multicenter study Open
Background The aim of this study was to explore predictors and construct a nomogram for risk stratification in primary extragastric mucosa‐associated lymphoid tissue (MALT) lymphoma. Methods Extragastric MALT lymphoma cases newly diagnosed…
View article: Efficacy of Adjuvant EGFR Inhibitors and Impact of Clinical Factors in Resected <i>EGFR</i> -mutated non-small-cell Lung Cancer: A Meta-Analysis
Efficacy of Adjuvant EGFR Inhibitors and Impact of Clinical Factors in Resected <i>EGFR</i> -mutated non-small-cell Lung Cancer: A Meta-Analysis Open
Background: The role of adjuvant EGFR tyrosine kinase inhibitors (TKIs) in resected EGFR-mutated non-small-cell lung cancer (NSCLC) remains unclear. Materials & methods: We evaluated pooled hazard ratio and 95% CI for …
View article: H3K27 acetylation activated-COL6A1 promotes osteosarcoma lung metastasis by repressing STAT1 and activating pulmonary cancer-associated fibroblasts: Erratum
H3K27 acetylation activated-COL6A1 promotes osteosarcoma lung metastasis by repressing STAT1 and activating pulmonary cancer-associated fibroblasts: Erratum Open
[This corrects the article DOI: 10.7150/thno.51245.].
View article: Analysis of the tumor microenvironment and mutation burden identifies prognostic features in thymic epithelial tumors.
Analysis of the tumor microenvironment and mutation burden identifies prognostic features in thymic epithelial tumors. Open
Thymic epithelial tumors (TETs) are one of the rarest adult malignancies in the anterior mediastinum. Thymic carcinomas (TCs) are less prevalent among TETs, but they are more clinically aggressive. Immunotherapy has emerged as a promising …
View article: Predictive value of a reduction in the level of high-density lipoprotein-cholesterol in patients with non-small-cell lung cancer undergoing radical resection and adjuvant chemotherapy: a retrospective observational study
Predictive value of a reduction in the level of high-density lipoprotein-cholesterol in patients with non-small-cell lung cancer undergoing radical resection and adjuvant chemotherapy: a retrospective observational study Open
View article: Role of Exosomal microRNAs and lncRNAs in the Follicular Fluid of Women With Polycystic Ovary Syndrome
Role of Exosomal microRNAs and lncRNAs in the Follicular Fluid of Women With Polycystic Ovary Syndrome Open
Polycystic ovary syndrome (PCOS) is a complex class of endocrine disorders with insulin resistance, compensatory hyperinsulinaemia and obesity. However, the pathogenesis and therapies of PCOS have not been fully elucidated. Exosomal miRNAs…
View article: Modification of Pathologic T Classification for Non-small Cell Lung Cancer With Visceral Pleural Invasion
Modification of Pathologic T Classification for Non-small Cell Lung Cancer With Visceral Pleural Invasion Open
View article: PD0325901, an ERK inhibitor, enhances the efficacy of PD-1 inhibitor in non-small cell lung carcinoma
PD0325901, an ERK inhibitor, enhances the efficacy of PD-1 inhibitor in non-small cell lung carcinoma Open
View article: Detection of human papillomavirus distinguishes second primary tumors from lung metastases in patients with squamous cell carcinoma of the cervix
Detection of human papillomavirus distinguishes second primary tumors from lung metastases in patients with squamous cell carcinoma of the cervix Open
Background In patients with squamous cell carcinoma of the cervix (SCCC), a squamous cell carcinoma (SqCC) in the lung represents either a second primary tumor or metastasis. This distinction between second primary tumors and lung metastas…
View article: <p>A New Immunological Prognostic Model Based on Immunohistochemistry for Extranodal Natural Killer/T-Cell Lymphoma Patients After Non-Anthracycline-Based Chemotherapy</p>
A New Immunological Prognostic Model Based on Immunohistochemistry for Extranodal Natural Killer/T-Cell Lymphoma Patients After Non-Anthracycline-Based Chemotherapy Open
This study is the first to validate the prognostic value of nPD-L1 and tumor-infiltrating FoxP3+Tregs in ENKTL; the new immunological prognostic model might be used to stratify ENKTL patients in clinical trials for new therapeutic strategi…
View article: Effects of Vitrification on the Imprinted Gene Snrpn in Neonatal Placental Tissue
Effects of Vitrification on the Imprinted Gene Snrpn in Neonatal Placental Tissue Open
Objective: To investigate the effects of vitrification on the expression of the imprinted gene Snrpn in neonatal placental tissue.Methods: Neonatal placental tissue was collected from women with natural pregnancy (control group) and from w…
View article: Erratum to Inactivation of FOXO1 induces T follicular cell polarization and involves angioimmunoblastic T cell lymphoma
Erratum to Inactivation of FOXO1 induces T follicular cell polarization and involves angioimmunoblastic T cell lymphoma Open
In the published article[1][1], an error appeared in Acknowledgments on page 753. We omitted Natural Science Foundation of Guangdong Province from Acknowledgments, and we updated it as below. We apologize for the errors and for any confusi…
View article: Expression of P63 and its correlation with prognosis in diffuse large B-cell lymphoma: a single center experience
Expression of P63 and its correlation with prognosis in diffuse large B-cell lymphoma: a single center experience Open
View article: Inactivation of FOXO1 induces T follicular cell polarization and involves angioimmunoblastic T cell lymphoma
Inactivation of FOXO1 induces T follicular cell polarization and involves angioimmunoblastic T cell lymphoma Open
Objective Angioimmunoblastic T cell lymphoma (AITL) is an aggressive form of non-Hodgkin lymphoma derived from mature T cells. However, the underlying pathogenesis of AITL remains unresolved. We aimed to explore the role of FOXO1-mediated …
View article: A prognostic index for nasal‐type early‐stage extranodal natural killer/T‐cell lymphoma: A multicenter study
A prognostic index for nasal‐type early‐stage extranodal natural killer/T‐cell lymphoma: A multicenter study Open
Extranodal natural killer/T-cell lymphoma (ENKTL) is a rare, distinctive clinicopathologic disease entity with aggressive clinical features and a strong association with the Epstein–Barr virus (EBV) infection.1, 2 Conventional prognostic i…
View article: Dose-Dense Rituximab-CHOP versus Standard Rituximab-CHOP in Newly Diagnosed Chinese Patients with Diffuse Large B-Cell Lymphoma: A Randomized, Multicenter, Open-Label Phase 3 Trial
Dose-Dense Rituximab-CHOP versus Standard Rituximab-CHOP in Newly Diagnosed Chinese Patients with Diffuse Large B-Cell Lymphoma: A Randomized, Multicenter, Open-Label Phase 3 Trial Open
R-CHOP-14 did not improve the outcome of DLBCL compared to R-CHOP-21 in Asian population. With manageable and similar toxicities, both of the two regimens were suitable for Asian DLBCL patients. For high-risk patients with IPI ≥ 2, new com…
View article: [Clinical characteristics and prognosis in 12 patients with adult T cell leukemia/lymphoma confirmed by HTLV-1 provirus gene detection].
[Clinical characteristics and prognosis in 12 patients with adult T cell leukemia/lymphoma confirmed by HTLV-1 provirus gene detection]. Open
Objective: To analyze the clinical characteristics and prognosis of adult T cell leukemia/lymphoma (ATLL). Methods: Peripheral blood samples from patients who were suspected as ATLL from March, 2013 to July, 2015, were collec…
View article: The Reproductive Toxicity of CdSe/ZnS Quantum Dots on the in vivo Ovarian Function and in vitro Fertilization
The Reproductive Toxicity of CdSe/ZnS Quantum Dots on the in vivo Ovarian Function and in vitro Fertilization Open
Despite the usefulness of quantum dots (QDs) in biomedicine and optoelectronics, their toxicity risks remain a major obstacle for clinical usages. Hence, we studied the reproductive toxicity of CdSe/ZnS QDs on two aspects, (i) in vivo ovar…
View article: Association between angiotensinogen T174M polymorphism and ischemic stroke: A meta-analysis
Association between angiotensinogen T174M polymorphism and ischemic stroke: A meta-analysis Open
In conclusion, the AGT T174M polymorphism may be a susceptible predictor of the risk of IS in Asians. Further, large and well-designed studies are needed to confirm this conclusion.