Suxia Wang
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View article: Ultrasonographic features of IgG4-related kidney disease: diagnostic value and correlation with clinical-pathological findings
Ultrasonographic features of IgG4-related kidney disease: diagnostic value and correlation with clinical-pathological findings Open
Objective To systematically characterize the ultrasonographic features of biopsy-proven IgG4-related kidney disease (IgG4-RKD) and to evaluate their correlation with key clinicopathological parameters. Methods In this retrospective study, …
View article: Renal interstitial infiltration by non-Hodgkin lymphoma: clinicopathological features, outcomes, and prognostic markers from a Chinese biopsy cohort
Renal interstitial infiltration by non-Hodgkin lymphoma: clinicopathological features, outcomes, and prognostic markers from a Chinese biopsy cohort Open
Renal involvement by non-Hodgkin lymphoma (NHL) is under-recognized and often misdiagnosed as interstitial nephritis. Kidney biopsy remains the gold standard for confirming lymphoma interstitial infiltration. Currently, the histopathologic…
View article: Case Report: A rare case of concurrence of IgG4-related tubulointerstitial nephritis and renal Amyloid A amyloidosis
Case Report: A rare case of concurrence of IgG4-related tubulointerstitial nephritis and renal Amyloid A amyloidosis Open
Immunoglobulin G4-related disease (IgG4-RD) is a systemic immune-mediated fibroinflammatory condition affecting multiple organs. IgG4-related tubulointerstitial nephritis (IgG4-TIN) is the predominant pattern of kidney involvement. Amyloid…
View article: Case Report: Expanding the spectrum of renal involvement in adult-onset still’s disease: a case of focal proliferative glomerulonephritis and ischemic nephropathy
Case Report: Expanding the spectrum of renal involvement in adult-onset still’s disease: a case of focal proliferative glomerulonephritis and ischemic nephropathy Open
Adult-onset Still’s disease (AOSD) is a rare systemic inflammatory disorder characterized by high spiking fever, evanescent rash, and arthritis. Renal involvement in AOSD is uncommon but clinically significant, with varied manifestations s…
View article: Retroperitoneal anastomotic hemangioma with significant steatosis: A case report and literature review
Retroperitoneal anastomotic hemangioma with significant steatosis: A case report and literature review Open
Rationale: Anastomosing hemangioma (AH) is a rare variant of hemangioma that was proposed in 2020. It is primarily located in the genitourinary tract, though it can occasionally be found in the retroperitoneum. Typically, classic hemangiom…
View article: Comparative analysis of clinicopathological characteristics and prognostic outcomes in fumarate hydratase-deficient renal cell carcinoma versus high-grade papillary renal cell carcinoma
Comparative analysis of clinicopathological characteristics and prognostic outcomes in fumarate hydratase-deficient renal cell carcinoma versus high-grade papillary renal cell carcinoma Open
Patients who are younger, have advanced pathological stages, or exhibit sarcomatoid differentiation should undergo mandatory immunohistochemical staining for FH and molecular testing to prevent misdiagnosis as conventional pRCC. Despite it…
View article: Validation of a renal staging system and its association with renal amyloid deposition burden in AL amyloidosis
Validation of a renal staging system and its association with renal amyloid deposition burden in AL amyloidosis Open
These findings suggest that in the renal staging system, eGFR - but not proteinuria - is significantly associated with amyloid deposition and independently affects renal survival.
View article: CD38hi macrophages promote fibrotic transition following acute kidney injury by modulating NAD+ metabolism
CD38hi macrophages promote fibrotic transition following acute kidney injury by modulating NAD+ metabolism Open
Acute kidney injury (AKI) encompasses a spectrum of conditions, varying from mild and self-limiting to severe cases that can lead to chronic kidney disease (CKD). Macrophages are crucial in the progression from AKI to CKD, yet the diversit…
View article: Advancing the clinical assessment of glomerular podocyte pathology in kidney biopsies via super-resolution microscopy and angiopoietin-like 4 staining
Advancing the clinical assessment of glomerular podocyte pathology in kidney biopsies via super-resolution microscopy and angiopoietin-like 4 staining Open
Rationale: The tertiary structure of normal podocytes prevents protein from leaking into the urine. However, observing the complexity of podocytes is challenging because of the scale differences in their three-dimensional structure and the…
View article: NLRP3 inflammasome activation and macrophage distribution in kidney tissues from patients with acute oxalate nephropathy
NLRP3 inflammasome activation and macrophage distribution in kidney tissues from patients with acute oxalate nephropathy Open
Background: The current study was initiated to evaluate renal nucleotide-binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome pathway activation and macrophage subtype distribution and thei…
View article: Postpartum Renal Cortical Necrosis: A Case Series
Postpartum Renal Cortical Necrosis: A Case Series Open
We identified key pathologic features in patients with postpartum RCN and atypical hemolytic uremic syndrome, highlighting the necessity for more effective therapeutic options. There is a clear demand for noninvasive biomarkers that can ac…
View article: Determinants and impact of calcium oxalate crystal deposition on renal outcomes in acute kidney injury patients
Determinants and impact of calcium oxalate crystal deposition on renal outcomes in acute kidney injury patients Open
Calcium oxalate (CaOx) crystal deposition in acute kidney injury (AKI) patients is under recognized but impacts renal outcomes. This study investigates its determinants and effects. We studied 814 AKI patients with native kidney biopsies f…
View article: Granulomatosis with polyangiitis presented as multiple cutaneous abscesses after hysterectomy
Granulomatosis with polyangiitis presented as multiple cutaneous abscesses after hysterectomy Open
To the Editor: A 62-year-old woman presented to the dermatology department with a 5-month history of multiple painless cutaneous abscesses and ulcers [Figure 1A], occurring 1 month after a transvaginal hysterectomy due to uterine prolapse.…
View article: Influence of rhythmic-movement activity intervention on hot executive function of 5- to 6-year-old children
Influence of rhythmic-movement activity intervention on hot executive function of 5- to 6-year-old children Open
Hot Executive Function (hot EF) refers to cognitive process involved in high emotion or motivation, and the operation of this function is related to the activities of the ventromedial prefrontal lobe and orbitofrontal lobe. Meanwhile, rhyt…
View article: Light-chain proximal tubulopathy: a retrospective study from a single Chinese nephrology referral center
Light-chain proximal tubulopathy: a retrospective study from a single Chinese nephrology referral center Open
Background: Light-chain proximal tubulopathy (LCPT) is a rare disease characterized by the accumulation of monoclonal light chains within proximal tubular cells. This study aimed to investigate the clinical characteristics of LCPT from a s…
View article: Histologic and Clinical Factors Associated with Kidney Outcomes in IgA Vasculitis Nephritis
Histologic and Clinical Factors Associated with Kidney Outcomes in IgA Vasculitis Nephritis Open
Background Nephritis is a common manifestation of IgA vasculitis and is morphologically indistinguishable from IgA nephropathy. While MEST-C scores are predictive of kidney outcomes in IgA nephropathy, their value in IgA vasculitis nephrit…
View article: Late-onset Renal involvement presenting with TMA and tubular injury in cobalamin C disease: a report of three cases and review of the literature
Late-onset Renal involvement presenting with TMA and tubular injury in cobalamin C disease: a report of three cases and review of the literature Open
Background: Mutation of methylmalonic aciduria type C and homocystinuria ( MMACHC ) gene causes inherited cobalamin C disease (cblC), an inborn error of cobalamin metabolism, which presents with methylmalonic aciduria (MMA) and homocystinu…
View article: Characteristics of Complement Protein Deposition in Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition
Characteristics of Complement Protein Deposition in Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposition Open
Background Hypocomplementemia and complement co-deposition with monoclonal immunoglobulins in glomeruli are not rare in proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID). Deposition of monoclonal immunoglobu…
View article: Editorial: Global excellence in nephrology: Asia and Australasia
Editorial: Global excellence in nephrology: Asia and Australasia Open
EDITORIAL article Front. Nephrol., 14 July 2023Sec. Critical Care Nephrology Volume 3 - 2023 | https://doi.org/10.3389/fneph.2023.1248728
View article: Primary membranous nephropathy in two siblings with one combined with anti-glomerular basement membrane disease: a case report
Primary membranous nephropathy in two siblings with one combined with anti-glomerular basement membrane disease: a case report Open
Background The phospholipase A2 receptor (PLA2R) associated with membranous nephropathy (MN) is an organ-specific autoimmune disease associated with PLA2R and human leukocyte antigen ( HLA ) genes. Familial PLA2R-related MN is rarely repor…