Suya Zhang
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View article: Osteoking exerts pro‑osteogenic and anti‑adipogenic effects in promoting bone fracture healing via EGF/EGFR/HDAC1/Wnt/β‑catenin signaling
Osteoking exerts pro‑osteogenic and anti‑adipogenic effects in promoting bone fracture healing via EGF/EGFR/HDAC1/Wnt/β‑catenin signaling Open
Bone fractures, as a global public health issue, lead to disability and reduce the quality of life for patients. Chinese patent drug Osteoking has efficacy in bone fracture therapy. However, its therapeutic properties and underlying mechan…
View article: Single‑cell transcriptomic analysis revealed the tumor‑associated microenvironment of papillary thyroid carcinoma with metastasis
Single‑cell transcriptomic analysis revealed the tumor‑associated microenvironment of papillary thyroid carcinoma with metastasis Open
Papillary thyroid cancer (PTC) is frequently associated with inflammation and lymph node metastasis. Single-cell RNA sequencing (scRNA-seq) is a powerful tool to uncover rare cellular subpopulations and investigate the diverse functions in…
View article: Transoral endoscopic resection of giant intracapsular high-grade ductal carcinoma within ex-pleomorphic adenoma in the parapharyngeal space: A case report and literature review
Transoral endoscopic resection of giant intracapsular high-grade ductal carcinoma within ex-pleomorphic adenoma in the parapharyngeal space: A case report and literature review Open
View article: Osteoking promotes bone formation and bone defect repair through ZBP1–STAT1–PKR–MLKL-mediated necroptosis
Osteoking promotes bone formation and bone defect repair through ZBP1–STAT1–PKR–MLKL-mediated necroptosis Open
Background Osteoking has been used for fracture therapy with a satisfying clinical efficacy. However, its therapeutic properties and the underlying mechanisms remain elusive. Method A bone defect rat model was established to evaluate the p…
View article: Osteoking Promotes Bone Formation and Bone Defect Repair through ZBP1-STAT1-PKR-MLKL-mediated Necroptosis
Osteoking Promotes Bone Formation and Bone Defect Repair through ZBP1-STAT1-PKR-MLKL-mediated Necroptosis Open
Background: Osteoking has been used for fracture therapy with a satisfying clinical efficacy. However, its therapeutic properties and the underlying mechanisms remain elusive. Method: A bone defect rat model was established to evaluate the…
View article: Single-cell transcriptomic analysis revealed the tumor-associated microenvironment of papillary thyroid carcinoma with metastasis
Single-cell transcriptomic analysis revealed the tumor-associated microenvironment of papillary thyroid carcinoma with metastasis Open
Background Papillary thyroid cancer (PTC) is frequently associated with inflammation and lymph node (LN) metastasis. Single-cell RNA sequencing (scRNA-seq) can uncover rare sub-populations of cells and explore functional heterogeneity of t…
View article: Apolipoprotein E Gene Polymorphism Effects on Lipid Metabolism and Risk of Cerebral Infarction in Northwest Han Chinese Population
Apolipoprotein E Gene Polymorphism Effects on Lipid Metabolism and Risk of Cerebral Infarction in Northwest Han Chinese Population Open
This study demonstrated that ε4 allele is independent risk factors for CI among patients in Northwest China. ApoE polymorphism was associated with CI, which was partly mediated through blood lipids and may also be mediated through non-lipi…
View article: Fission-track thermochronological evidence for the Yanshanian tectonic evolution of the northern Junggar Basin, northwest China
Fission-track thermochronological evidence for the Yanshanian tectonic evolution of the northern Junggar Basin, northwest China Open
The Junggar Basin is a multicycle intracontinental sedimentary basin developed on the pre-Mesozoic deformed basement. For a long time, the Junggar Basin and its adjacent Altai orogeny have been a focus of debate for geologists studying the…
View article: Development of a Near-Infrared Fluorescent Probe Based on Nile Red for ONOO<sup>–</sup> and Its Imaging Applications
Development of a Near-Infrared Fluorescent Probe Based on Nile Red for ONOO<sup>–</sup> and Its Imaging Applications Open
基于尼罗红类 ONOO -近红外荧光探针的开发及其成像应用 贺晓梦 袁方 张素雅 张健健 * (西北大学化学与材料科学学院 西安 710021) 摘要 过氧亚硝酸根(ONOO -)在氧化应激和炎症过程中的生成与细胞损伤、炎症反应和免疫调节等密切相关, 因此, 开发高灵敏且高度选择性的 ONOO -检测方法对于深入理解疾病发生和发展机制、提高疾病的早期诊断和治疗水平具 有极其重要意义.设计合成了一种选择性检测 ONOO -的新型荧光探针 NR-Pro.该探针通过使用烷基链将 …
View article: Effect of Apolipoprotein E ε4 Allele on the Progression of Carotid Atherosclerosis Through Apolipoprotein Levels
Effect of Apolipoprotein E ε4 Allele on the Progression of Carotid Atherosclerosis Through Apolipoprotein Levels Open
This study provides convincing evidence that ε4 allele, hypertension, ApoA-I, LDL-C and TG levels are independent risk factor for CAS in the ShaanXi Han populations. ApoE polymorphism was associated with CAS and this association was partly…
View article: Apolipoprotein E Gene Polymorphism Effects on Lipid Metabolism and Risk of Cerebral Infarction in Northwest Han Chinese Population
Apolipoprotein E Gene Polymorphism Effects on Lipid Metabolism and Risk of Cerebral Infarction in Northwest Han Chinese Population Open
Background: The apolipoprotein E (ApoE) genetic variation may be involved in the development of Cerebral Infarction (CI). Serum lipid levels are known risk factors for CI, but the effect of the ApoE gene polymorphism on lipid metabolism re…
View article: Reservoir characteristics analysis of Upper Paleozoic Permian He 8 formation in Qingyang area
Reservoir characteristics analysis of Upper Paleozoic Permian He 8 formation in Qingyang area Open
Through field geological survey, combined with outcrop and drilling data, the reservoir characteristics of Upper Paleozoic Permian He 8 formation in Qingyang area are comprehensively analyzed. The results show that the He 8 formation in Qi…
View article: Characteristics of Chang 7 shale in Qingyang area, Ordos Basin
Characteristics of Chang 7 shale in Qingyang area, Ordos Basin Open
Chang-7 shale is the most important source rock of Mesozoic in Ordos Basin. The characteristics of Chang 7 shale in Longdong area of Ordos Basin are analyzed from the aspects of shale thickness, distribution, sedimentation, petrology and o…
View article: Characteristics of paleogeothermal field and its influence on hydrocarbon accumulation in Qingyang area
Characteristics of paleogeothermal field and its influence on hydrocarbon accumulation in Qingyang area Open
Geothermal field has an important influence on hydrocarbon accumulation. The geotemperature field in Qingyang area is studied by vitrinite reflectance and homogenization temperature of inclusions. The results show that the average geotherm…
View article: VSAM-Based Visual Keyword Generation for Image Caption
VSAM-Based Visual Keyword Generation for Image Caption Open
Image caption is to understand and describe the visual content, which is expected to be applied in automatic news reporting in future. In recent years, there has been an increasing interest in an Encoder-Decoder framework for image caption…
View article: Analysis of Performance and Stability Factors of Vehicle Ethanol Gasoline for Motor Vehicle
Analysis of Performance and Stability Factors of Vehicle Ethanol Gasoline for Motor Vehicle Open
Ethanol gasoline is a new type of clean energy which is formed by mixing fuel ethanol and ordinary gasoline in a certain proportion. The use of ethanol gasoline in motor vehicles can reduce the emissions of exhaust pollutants and improve t…
View article: Study on Rock Mechanics Parameters of Benxi Formation in Yanchang gas field, Ordos Basin
Study on Rock Mechanics Parameters of Benxi Formation in Yanchang gas field, Ordos Basin Open
Rock mechanics parameters can reflect the brittleness of the formation and determine the effect of reservoir fracturing, and they are very important for improving unconventional oil and gas production. Triaxial compression test and acousti…
View article: Brittleness Evaluation of Chang7 Reservoir in Longdong Area Based on Mechanical Parameters and Stress-strain
Brittleness Evaluation of Chang7 Reservoir in Longdong Area Based on Mechanical Parameters and Stress-strain Open
Brittleness determines the effect of reservoir fracturing and is the key to improve unconventional oil and gas production. In order to accurately understand the brittleness and fracture parameters of the reservoir, triaxial compression tes…
View article: The study of Yanshanian unconformity tectonic events in Northern Junggar Basin
The study of Yanshanian unconformity tectonic events in Northern Junggar Basin Open
Based on the background of Yanshanian tectonic activity in the northern Junggar basin, the temporal and spatial distribution characteristics of Yanshanian unconformity events in the northern Junggar basin are systematically studied through…
View article: Study on the Controlling Factors of Coal Seam Distribution in Jurassic Yan’an Formation in Longdong Area in Ordos Basin
Study on the Controlling Factors of Coal Seam Distribution in Jurassic Yan’an Formation in Longdong Area in Ordos Basin Open
The distribution characteristics of coal seams and the main controlling factors of coal accumulation of the Middle Jurassic Yan’an Formation in Longdong area are analyzed in this paper based on geophysical logging data, drilling data and s…
View article: The Study on Brittleness Evaluation of Chang 7 Reservoir in Longdong Area in Ordos Basin
The Study on Brittleness Evaluation of Chang 7 Reservoir in Longdong Area in Ordos Basin Open
Brittleness is very important in the fracability evaluation and exploration of unconventional oil and gas. In this paper, the rock mechanics parameter method and the mineral composition method are used in order to calculate the brittleness…
View article: Analysis on Geological Conditions of Chang 7 Shale Gas Accumulation in Longdong Area in Ordos Basin
Analysis on Geological Conditions of Chang 7 Shale Gas Accumulation in Longdong Area in Ordos Basin Open
The geological conditions of Chang 7 shale gas accumulation in Longdong area are analyzed from sedimentology, petrology and organic geochemical characteristics in this paper. The study shows that Chang 7 shale in Longdong area is mainly de…
View article: Brittleness Logging Evaluation of Shihezi Formation in Yanchang Gas Field in Ordos Basin Based on Rock Mechanical Characteristics
Brittleness Logging Evaluation of Shihezi Formation in Yanchang Gas Field in Ordos Basin Based on Rock Mechanical Characteristics Open
Brittleness determines the effect of reservoir fracturing and is important for increasing the production of unconventional oil and gas. The reservoir of Yanchang gas field is characterized by low porosity, low permeability and strong heter…
View article: Study on Rock Mechanics Parameters of Chang 7 Shale in Longdong Area in Ordos Basin
Study on Rock Mechanics Parameters of Chang 7 Shale in Longdong Area in Ordos Basin Open
Rock samples from X-1 and X-2 well of Chang 7 shale in Longdong area in Ordos Basin are studied through triaxial compression test and acoustic wave test in order to obtain accurate data about the mechanical characteristics of the stratum a…
View article: Analysis on the Theory and Practice of Petroleum Exploration Geology in Ordos Basin
Analysis on the Theory and Practice of Petroleum Exploration Geology in Ordos Basin Open
The Ordos Basin is a large inland depression basin.The basin is surrounded by highland denudation zones.The water system extends to the lake basin, forming multiple sets of river-lake phase terrigenous clastic sediments.The lithofacies bel…
View article: MicroRNA profiling in the dentate gyrus in epileptic rats
MicroRNA profiling in the dentate gyrus in epileptic rats Open
This study aimed to explore the role of aberrant miRNA expression in epilepsy and to identify more potential genes associated with epileptogenesis.The miRNA expression profile of GSE49850, which included 20 samples from the rat epileptic d…
View article: Gene expression profile analysis of colorectal cancer to investigate potential mechanisms using&nbsp;bioinformatics
Gene expression profile analysis of colorectal cancer to investigate potential mechanisms using bioinformatics Open
This study aimed to explore the underlying molecular mechanisms of colorectal cancer (CRC) using bioinformatics analysis. Using GSE4107 datasets downloaded from the Gene Expression Omnibus, the differentially expressed genes (DEGs) were sc…