Suyuan Zhang
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View article: Tracing the origin of testosterone-producing Leydig cells during pubertal development, homeostasis, and regeneration
Tracing the origin of testosterone-producing Leydig cells during pubertal development, homeostasis, and regeneration Open
View article: Improving Urban Streetscape Design Guidelines by Incorporating Street Vendor Factors: A Review
Improving Urban Streetscape Design Guidelines by Incorporating Street Vendor Factors: A Review Open
View article: Impaired ketogenesis in Leydig Cells drives testicular aging
Impaired ketogenesis in Leydig Cells drives testicular aging Open
View article: Treatment patterns and outcomes in HER2-low metastatic breast cancer patients previously treated with chemotherapy: a US real-world cohort study
Treatment patterns and outcomes in HER2-low metastatic breast cancer patients previously treated with chemotherapy: a US real-world cohort study Open
View article: Electrocatalysis in MOF Films for Flexible Electrochemical Sensing: A Comprehensive Review
Electrocatalysis in MOF Films for Flexible Electrochemical Sensing: A Comprehensive Review Open
Flexible electrochemical sensors can adhere to any bendable surface with conformal contact, enabling continuous data monitoring without compromising the surface’s dynamics. Among various materials that have been explored for flexible elect…
View article: Electrocatalysis in MOF Films for Flexible Electrochemical Sensing: A Comprehensive Review
Electrocatalysis in MOF Films for Flexible Electrochemical Sensing: A Comprehensive Review Open
Flexible electrochemical sensors can adhere to any bendable surface with conformal contact, enabling continuous data monitoring without compromising the surface's dynamics. Among various materials that have been explored for flexible …
View article: Impaired ketogenesis in Leydig Cells drives testicular aging
Impaired ketogenesis in Leydig Cells drives testicular aging Open
Testicular aging commonly leads to testosterone deficiency and impaired spermatogenesis, yet the underlying mechanisms remain elusive. Here, a comprehensive analysis of senescence landscapes in mice testes during aging revealed that the Le…
View article: <scp>AAV</scp>‐mediated gene therapy restores natural fertility and improves physical function in the <i>Lhcgr</i>‐deficient mouse model of <scp>Leydig</scp> cell failure
<span>AAV</span>‐mediated gene therapy restores natural fertility and improves physical function in the <i>Lhcgr</i>‐deficient mouse model of <span>Leydig</span> cell failure Open
Leydig cell failure (LCF) caused by gene mutations leads to testosterone deficiency, infertility and reduced physical function. Adeno‐associated virus serotype 8 (AAV8)‐mediated gene therapy shows potential in treating LCF in the Lhcgr‐def…
View article: Precise Correction of <i>Lhcgr</i> Mutation in Stem Leydig Cells by Prime Editing Rescues Hereditary Primary Hypogonadism in Mice
Precise Correction of <i>Lhcgr</i> Mutation in Stem Leydig Cells by Prime Editing Rescues Hereditary Primary Hypogonadism in Mice Open
Hereditary primary hypogonadism (HPH), caused by gene mutation related to testosterone synthesis in Leydig cells, usually impairs male sexual development and spermatogenesis. Genetically corrected stem Leydig cells (SLCs) transplantation m…
View article: Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological features
Early hepatoid adenocarcinoma of the stomach with signet ring cell carcinoma: A case report and clinicopathological features Open
Background Hepatoid adenocarcinoma of the stomach (HAS) is a rare subtype of gastric cancer with poor prognosis, and its clinicopathological features are not well understood, so the pathology from the clinical biopsy is easily misdiagnosed…
View article: AAV-mediated gene therapy produces fertile offspring in the Lhcgr-deficient mouse model of Leydig cell failure
AAV-mediated gene therapy produces fertile offspring in the Lhcgr-deficient mouse model of Leydig cell failure Open
Leydig cell failure (LCF) caused by gene mutation results in testosterone deficiency and infertility. Serum testosterone levels can be recovered via testosterone replacement; however, established therapies have shown limited success in res…
View article: Serum miR-21 predicts the prognosis of patients with primary gastrointestinal diffuse large B-cell lymphoma
Serum miR-21 predicts the prognosis of patients with primary gastrointestinal diffuse large B-cell lymphoma Open
Background: Primary gastrointestinal diffuse large B-cell lymphoma (PGI-DLBCL) lacks specific clinical manifestations and its malignancy renders prognostication and choice of treatment strategy difficult. The aim of this study was to evalu…
View article: Assessing Safety Risk Management Performance in Chinese Subway Construction Projects: A Multistakeholder Perspective
Assessing Safety Risk Management Performance in Chinese Subway Construction Projects: A Multistakeholder Perspective Open
The rapid development of subway projects in China presents significant safety risks to those involved. Building on the previous empirical research that identified and classified the safety risks of these projects, the aim of this paper is …
View article: Template-free synthesis of non-noble metal single-atom electrocatalyst with N-doped holey carbon matrix for highly efficient oxygen reduction reaction in zinc-air batteries
Template-free synthesis of non-noble metal single-atom electrocatalyst with N-doped holey carbon matrix for highly efficient oxygen reduction reaction in zinc-air batteries Open
View article: Electrocatalytic Reduction Catalysts: Hollow Mesoporous Carbon Sphere Loaded Ni–N<sub>4</sub> Single‐Atom: Support Structure Study for CO<sub>2</sub> Electrocatalytic Reduction Catalyst (Small 41/2020)
Electrocatalytic Reduction Catalysts: Hollow Mesoporous Carbon Sphere Loaded Ni–N<sub>4</sub> Single‐Atom: Support Structure Study for CO<sub>2</sub> Electrocatalytic Reduction Catalyst (Small 41/2020) Open
In article number 2003943, Hongfang Li, Rong Cao, and co-workers successfully synthesize a hollow mesoporous carbon sphere loaded Ni–N4 single-atom catalyst that exhibits superior catalytic activity toward CO2 electrocatalytic reduction. T…
View article: ALK-1-positive inflammatory myofibroblastic tumor of the thyroid complicated by Hashimoto’s thyroiditis: report of a rare case and a literature review
ALK-1-positive inflammatory myofibroblastic tumor of the thyroid complicated by Hashimoto’s thyroiditis: report of a rare case and a literature review Open
View article: Medullary thyroid carcinoma combined with papillary thyroid carcinoma: case report and literature review.
Medullary thyroid carcinoma combined with papillary thyroid carcinoma: case report and literature review. Open
We investigated the clinicopathologic features, immunophenotype, (differential) diagnosis, pathogenesis, treatment, and follow-up of medullary thyroid carcinoma (MTC) combined with papillary thyroid carcinoma (PTC). A retrospective analysi…
View article: Unraveling the Reactivity and Selectivity of Atomically Isolated Metal–Nitrogen Sites Anchored on Porphyrinic Triazine Frameworks for Electroreduction of CO <sub>2</sub>
Unraveling the Reactivity and Selectivity of Atomically Isolated Metal–Nitrogen Sites Anchored on Porphyrinic Triazine Frameworks for Electroreduction of CO <sub>2</sub> Open
Open AccessCCS ChemistryRESEARCH ARTICLE1 Oct 2019Unraveling the Reactivity and Selectivity of Atomically Isolated Metal–Nitrogen Sites Anchored on Porphyrinic Triazine Frameworks for Electroreduction of CO2 Ying Hou, Yuan-Biao Huang, Yu-L…
View article: CCDC 1893955: Experimental Crystal Structure Determination
CCDC 1893955: Experimental Crystal Structure Determination Open
View article: Giant recurrent mixed-type liposarcoma of the retroperitoneum: report of a case and review of literature.
Giant recurrent mixed-type liposarcoma of the retroperitoneum: report of a case and review of literature. Open
Retroperitoneal liposarcoma is a rare tumor with an incidence of 2.5 per million individuals, especially tumors of mixed histologic pattern. We present a case of a 63-year-old woman with a history of slowly increasing abdominal volume over…
View article: Research and Development of the Advanced High Strength Steel for the Mining Machinery
Research and Development of the Advanced High Strength Steel for the Mining Machinery Open
Shougang has developed the advanced high strength steel(AHSS) of SQ690D for the lightweight heavy mining machinery by utilizing low carbon and microalloyed design and two-stage rolling coupled with purposeful heat treatment through quenchi…
View article: Development and application of super heavy gauge high-strength structural steel for high-rise buildings
Development and application of super heavy gauge high-strength structural steel for high-rise buildings Open
This paper presents development of 130mm S460G1-Z35 by using low carbon Nb-Ni-Mo-V-Ti micro-alloying design and two-stage rolling, quenching and tempering process. For the super heavy gauge high-strength structural steel, the yield strengt…
View article: Regional differences of NOX emission and its causes in China
Regional differences of NOX emission and its causes in China Open
There is a significant regional difference of NOX emission in China; the total emission amount of economic developed areas is larger while the economic developing regions are relative smaller.From the point of view of the changes, the tota…