Suzanne Abbring
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View article: Induction of endotoxin tolerance in murine monocyte and macrophage cell populations – optimal LPS dose and compartment-specific reversal by β-glucan
Induction of endotoxin tolerance in murine monocyte and macrophage cell populations – optimal LPS dose and compartment-specific reversal by β-glucan Open
Dietary β-glucan has the potential to selectively counteract LPS-induced immunosuppression.
View article: Dietary Intake of Yeast‐Derived β‐Glucan and Rice‐Derived Arabinoxylan Induces Dose‐Dependent Innate Immune Priming in Mice
Dietary Intake of Yeast‐Derived β‐Glucan and Rice‐Derived Arabinoxylan Induces Dose‐Dependent Innate Immune Priming in Mice Open
Beta‐glucans and arabinoxylans are known for their immunostimulatory properties. However, in vivo these have been documented almost exclusively following parenteral administration, underemphasizing oral intake. C57BL/6 mice are fed either …
View article: Raw Milk-Induced Protection against Food Allergic Symptoms in Mice Is Accompanied by Shifts in Microbial Community Structure
Raw Milk-Induced Protection against Food Allergic Symptoms in Mice Is Accompanied by Shifts in Microbial Community Structure Open
The mechanism underlying the allergy-protective effects of raw cow’s milk is still unknown, but the modulation of the gut microbiome may play a role. The effects of consuming raw cow’s milk or processed milk on fecal microbial communities …
View article: The Impact of Milk and Its Components on Epigenetic Programming of Immune Function in Early Life and Beyond: Implications for Allergy and Asthma
The Impact of Milk and Its Components on Epigenetic Programming of Immune Function in Early Life and Beyond: Implications for Allergy and Asthma Open
Specific and adequate nutrition during pregnancy and early life is an important factor in avoiding non-communicable diseases such as obesity, type 2 diabetes, cardiovascular disease, cancers, and chronic allergic diseases. Although epidemi…
View article: Direct Inhibition of the Allergic Effector Response by Raw Cow’s Milk—An Extensive In Vitro Assessment
Direct Inhibition of the Allergic Effector Response by Raw Cow’s Milk—An Extensive In Vitro Assessment Open
The mechanisms underlying the allergy-protective effects of raw cow’s milk are poorly understood. The current focus is mainly on the modulation of T cell responses. In the present study, we investigated whether raw cow’s milk can also dire…
View article: Loss of allergy-protective capacity of raw cow's milk after heat treatment coincides with loss of immunologically active whey proteins
Loss of allergy-protective capacity of raw cow's milk after heat treatment coincides with loss of immunologically active whey proteins Open
Whey proteins denaturing ≤65 °C are important for allergy protection by raw cow's milk.
View article: The potential of raw cow's milk to target allergic diseases: 'Well done, medium or rare?’
The potential of raw cow's milk to target allergic diseases: 'Well done, medium or rare?’ Open
Allergic diseases are a growing public health concern. They affect the lives of more than a billion people worldwide and their prevalence is expected to rise to four billion by 2050. This vast increase is often explained by the loss of rur…
View article: Raw Cow’s Milk Reduces Allergic Symptoms in a Murine Model for Food Allergy—A Potential Role for Epigenetic Modifications
Raw Cow’s Milk Reduces Allergic Symptoms in a Murine Model for Food Allergy—A Potential Role for Epigenetic Modifications Open
Epidemiological studies identified raw cow’s milk consumption as an important environmental exposure that prevents allergic diseases. In the present study, we investigated whether raw cow’s milk has the capacity to induce tolerance to an u…
View article: Suppression of Food Allergic Symptoms by Raw Cow’s Milk in Mice is Retained after Skimming but Abolished after Heating the Milk—A Promising Contribution of Alkaline Phosphatase
Suppression of Food Allergic Symptoms by Raw Cow’s Milk in Mice is Retained after Skimming but Abolished after Heating the Milk—A Promising Contribution of Alkaline Phosphatase Open
Raw cow’s milk was previously shown to suppress allergic symptoms in a murine model for food allergy. In the present study, we investigated the contribution of fat content and heat-sensitive milk components to this allergy-protective effec…
View article: Milk processing increases the allergenicity of cow’s milk—Preclinical evidence supported by a human proof‐of‐concept provocation pilot
Milk processing increases the allergenicity of cow’s milk—Preclinical evidence supported by a human proof‐of‐concept provocation pilot Open
Background Several studies demonstrated the adverse effect of milk processing on the allergy‐protective capacity of raw cow's milk. Whether milk processing also affects the allergenicity of raw milk is hardly investigated. Objective To ass…
View article: Raw Cow’s Milk Prevents the Development of Airway Inflammation in a Murine House Dust Mite-Induced Asthma Model
Raw Cow’s Milk Prevents the Development of Airway Inflammation in a Murine House Dust Mite-Induced Asthma Model Open
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View article: Post‐sensitization administration of non‐digestible oligosaccharides and <i>Bifidobacterium breve</i> M‐16V reduces allergic symptoms in mice
Post‐sensitization administration of non‐digestible oligosaccharides and <i>Bifidobacterium breve</i> M‐16V reduces allergic symptoms in mice Open
To support dietary management of severe cow's milk allergic infants, a synbiotic mixture of non‐digestible oligosaccharides and Bifidobacterium breve M‐16V ( B. breve ) was designed from source materials that are completely cow's milk‐free…