Suzanne Bruce
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View article: Red light photodynamic therapy with 10% aminolevulinic acid gel showed efficacy for treatment of superficial basal cell carcinoma in a randomized, vehicle controlled, double-blind, multicenter phase III study
Red light photodynamic therapy with 10% aminolevulinic acid gel showed efficacy for treatment of superficial basal cell carcinoma in a randomized, vehicle controlled, double-blind, multicenter phase III study Open
10% ALA gel showed significantly higher clearance rates than vehicle with unproblematic safety and positive esthetic outcome.
View article: Safe and Effective Restoration of Jawline Definition With Hyaluronic Acid Injectable Gel VYC-25L: Results From a Randomized Controlled Study
Safe and Effective Restoration of Jawline Definition With Hyaluronic Acid Injectable Gel VYC-25L: Results From a Randomized Controlled Study Open
Background A well-defined jawline improves overall facial aesthetics, motivating patients to seek jawline augmentation. Objectives In this study we evaluated the safety and effectiveness of the hyaluronic acid injectable gel VYC-25L for re…
View article: Efficacy of Roflumilast Foam, 0.3%, in Patients With Seborrheic Dermatitis
Efficacy of Roflumilast Foam, 0.3%, in Patients With Seborrheic Dermatitis Open
Importance Current topical treatment options for seborrheic dermatitis are limited by efficacy and/or safety. Objective To assess safety and efficacy of roflumilast foam, 0.3%, in adult patients with seborrheic dermatitis affecting the sca…
View article: Safety, Pharmacodynamic Response, and Treatment Satisfaction With OnabotulinumtoxinA 40 U, 60 U, and 80 U in Subjects With Moderate to Severe Dynamic Glabellar Lines
Safety, Pharmacodynamic Response, and Treatment Satisfaction With OnabotulinumtoxinA 40 U, 60 U, and 80 U in Subjects With Moderate to Severe Dynamic Glabellar Lines Open
Background OnabotulinumtoxinA 20 U reduces glabellar line (GL) severity at maximum frown for approximately 3 to 4 months. Small studies have suggested that >20-U doses may increase the efficacy and duration of response for GLs. Objectiv…
View article: Phase 2 randomized, dose-ranging trial of CTP-543, a selective Janus Kinase inhibitor, in moderate-to-severe alopecia areata
Phase 2 randomized, dose-ranging trial of CTP-543, a selective Janus Kinase inhibitor, in moderate-to-severe alopecia areata Open
Patients treated with CTP-543 (8 or 12 mg, twice daily) had a significant reduction in the severity of AA.
View article: A Randomized, Double-blind, Vehicle-Controlled Phase 2a Study Evaluating Once Daily Roflumilast Foam 0.3% in Patients With Moderate to Severe Seborrheic Dermatitis
A Randomized, Double-blind, Vehicle-Controlled Phase 2a Study Evaluating Once Daily Roflumilast Foam 0.3% in Patients With Moderate to Severe Seborrheic Dermatitis Open
N/A
View article: Setipiprant for Androgenetic Alopecia in Males: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 2a Trial
Setipiprant for Androgenetic Alopecia in Males: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 2a Trial Open
Setipiprant 1000 mg BID was safe and well tolerated but did not demonstrate efficacy versus placebo for scalp hair growth in men with AGA.
View article: Once-Daily Oral Sarecycline 1.5 mg/kg/day is Effective for Moderate to Severe Acne Vulgaris: Results from Two 12-Week, Phase 3, Randomized, Double-Blind Clinical Trials
Once-Daily Oral Sarecycline 1.5 mg/kg/day is Effective for Moderate to Severe Acne Vulgaris: Results from Two 12-Week, Phase 3, Randomized, Double-Blind Clinical Trials Open
not available.
View article: Tirbanibulin Ointment 1%, a Novel Inhibitor of Tubulin Polymerization and Src Kinase Signaling , for the Treatment of Actinic Keratosis (AK): Results from Two Pivotal Phase III Studies
Tirbanibulin Ointment 1%, a Novel Inhibitor of Tubulin Polymerization and Src Kinase Signaling , for the Treatment of Actinic Keratosis (AK): Results from Two Pivotal Phase III Studies Open
not available.
View article: A randomized, double blind, vehicle-controlled multicenter phase III study to evaluate the safety and efficacy of BF-200 ALA and narrowband red light in the treatment of superficial basal cell carcinoma (sBCC) with photodynamic therapy (PDT)
A randomized, double blind, vehicle-controlled multicenter phase III study to evaluate the safety and efficacy of BF-200 ALA and narrowband red light in the treatment of superficial basal cell carcinoma (sBCC) with photodynamic therapy (PDT) Open
not available.
View article: OnabotulinumtoxinA for Treatment of Moderate to Severe Crow's Feet Lines: A Review
OnabotulinumtoxinA for Treatment of Moderate to Severe Crow's Feet Lines: A Review Open
Lateral canthal lines or crow's feet lines (CFL) may be treated with onabotulinumtoxinA. We identified several key concepts important to understanding the use of onabotulinumtoxinA for treatment of moderate-to-severe CFL. To contextualize …
View article: Abstract: Polymethylmethacrylate-Collagen for the Correction of Moderate to Severe Atrophic Acne Scars: Results of a Randomized Double-Blind Multicenter Study with 12 Month Follow-Up
Abstract: Polymethylmethacrylate-Collagen for the Correction of Moderate to Severe Atrophic Acne Scars: Results of a Randomized Double-Blind Multicenter Study with 12 Month Follow-Up Open
BACKGROUND: Polymethylmethacrylate (PMMA)-collagen [Bellafill] consists of PMMA microspheres suspended in a carrier of bovine collagen gel.1 A Randomized Double-Blind study demonstrated the safety and effectiveness of this product in corre…
View article: OnabotulinumtoxinA for Treatment of Moderate to Severe Crow's Feet Lines: A Review
OnabotulinumtoxinA for Treatment of Moderate to Severe Crow's Feet Lines: A Review Open
Lateral canthal lines or crow's feet lines (CFL) may be treated with onabotulinumtoxinA. We identified several key concepts important to understanding the use of onabotulinumtoxinA for treatment of moderate-to-severe CFL. To contextualize …
View article: An evaluation of the safety and efficacy of bimatoprost for eyelash growth in pediatric subjects
An evaluation of the safety and efficacy of bimatoprost for eyelash growth in pediatric subjects Open
Bimatoprost was safe and well tolerated in pediatric subjects with eyelash hypotrichosis. In this study with limited sample size, subgroup analyses showed that treatment was effective in healthy adolescents with no concurrent contributing …
View article: <i>dsx<sup>GAL4</sup></i> is expressed in a subset of cells of the midgut.
<i>dsx<sup>GAL4</sup></i> is expressed in a subset of cells of the midgut. Open
(A) The frequency of cells expressing UAS-RedStinger nuclear DsRed reporter (magenta) varies along the length of the anterior midgut from an adult female. Non-expressing nuclei are marked with DAPI alone (blue). Anterior (a) and posterior …
View article: DSX is present in SOP daughters of the foreleg disc.
DSX is present in SOP daughters of the foreleg disc. Open
(A and B) DSX (magenta) is present across the tarsal segment epithelium in male discs at 0 h APF as well as in subsets of cells expressing ase-lacZ (green) in T5 (arrows) and T4 (boxed area). (B) Magnified view of boxed region in (A) shown…
View article: <i>dsx</i> regulates axonal morphology independent of GSO number.
<i>dsx</i> regulates axonal morphology independent of GSO number. Open
(A–F”) fruGAL4 driving UAS-mCD8::GFP (green) labels GRN cell bodies and axons. Forelegs of (A) control male (UAS-mCD8::GFP/SM6; fruGAL4/+ ), (B) male with feminized GRNs (UAS-DSXF/UAS-mCD8::GFP; fruGAL4/+), and (C) control female (UAS-mCD8…
View article: Superior efficacy of calcipotriene and betamethasone dipropionate aerosol foam versus ointment in patients with psoriasis vulgaris – A randomized phase II study
Superior efficacy of calcipotriene and betamethasone dipropionate aerosol foam versus ointment in patients with psoriasis vulgaris – A randomized phase II study Open
Cal/BD aerosol foam demonstrates significantly greater efficacy and similar tolerability compared with Cal/BD ointment for psoriasis treatment.
View article: Safety and Efficacy of Bimatoprost for Eyelash Growth in Postchemotherapy Subjects.
Safety and Efficacy of Bimatoprost for Eyelash Growth in Postchemotherapy Subjects. Open
NCT00907426.